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Nov 13 - Nov 15
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Nov 20 - Nov 22
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Recommended hotels in Perryville

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

1. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (645 reviews)
"Excellent stay , couldn't believe the property was 10 years old , it looks like it was just built , great place , highly recommend ."
United States
allan p.
The price is CA $141
CA $162 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Perryville by IHG
A hotel with a Super 8 sign, a covered entrance, and a brick facade.

2. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.6 out of 10, Excellent, (1,005 reviews)
"Nice room, friendly staff."
United States
Matthew
The price is CA $96
CA $110 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Perryville
A building with a sign that reads "The Atrium Boutique Hotel".

3. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (12 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is CA $123
CA $141 total
includes taxes & fees
Nov 21 - Nov 22
The Atrium - A Boutique Hotel
A Days Inn with a covered outdoor seating area and a brick building in the background.

4. Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
7.0 out of 10, Good, (464 reviews)
"Parking was good, smelled terribly"
United States
Jesse
The price is CA $100
CA $114 total
includes taxes & fees
Nov 8 - Nov 9
Days Inn by Wyndham Perryville
A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

5. Perryville RV Resort

Perryville RV Resort
2.0 star property
Perryville
8.8 out of 10, Excellent, (8 reviews)
"Staff is very helpful . beautiful campground"
United States
Kevin
The price is CA $113
CA $130 total
includes taxes & fees
Nov 8 - Nov 9
Perryville RV Resort
A hotel with a clear sign reading "Quality Inn" and "By Choice Hotels".

6. Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.8 out of 10, (145 reviews)
"Nice for a quick stay."
United States
Evelynmaryeka
The price is CA $89
CA $102 total
includes taxes & fees
Nov 26 - Nov 27
Quality Inn Perryville I-55
A building with a sign reading "URBAN LOFTS" and a storefront with a sign that says "STREET BREW."

7. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is CA $282
CA $435 total
includes taxes & fees
Nov 7 - Nov 8
Urban Lofts
A two-story building with a brick facade, large windows, and a storefront with awnings.

8. Downtown Urban Loft #9

Downtown Urban Loft #9
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"The Zen atmosphere made it really relaxing and the spa bathroom was incredible"
United States
Hunter
The price is CA $272
CA $427 total
includes taxes & fees
Nov 9 - Nov 10
Downtown Urban Loft #9
A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

9. The Mediterranean House 1858

The Mediterranean House 1858
2.0 star property
Perryville
The price is CA $612
CA $1,031 total
includes taxes & fees
Nov 11 - Nov 12
The Mediterranean House 1858
A two-story house with a front porch, a small garden, and a metal bench.

10. Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1 review)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is CA $713
CA $1,170 total
includes taxes & fees
Nov 9 - Nov 10
Gorgeous, downtown house!
A balcony with a metal railing overlooking a street with cars and buildings, including a church with a steeple.

11. Downtown Urban Loft #1

Downtown Urban Loft #1
Perryville
The price is CA $272
CA $427 total
includes taxes & fees
Nov 8 - Nov 9
Downtown Urban Loft #1
A wooden deck with a sofa, a hot tub, and string lights.

12. TreeLoft at BaseCamp

TreeLoft at BaseCamp
Perryville
10.0 out of 10, Exceptional, (5 reviews)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
The price is CA $482
CA $737 total
includes taxes & fees
Nov 24 - Nov 25
TreeLoft at BaseCamp
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

13. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
The price is CA $112
CA $118 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Jackson MO
A Holiday Inn Express & Suites hotel with a modern building facade, a covered entrance, and a landscaped lawn.

14. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (628 reviews)
"Cleanest hotel I’ve ever been in. Hotel breakfast was clean, hot, and so good compared to other hotels. The lady at the front desk (blond hair) was SO NICE!"
United States
Brianna
The price is CA $140
CA $155 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
A hotel with a covered entrance, brick exterior, and a parking lot.

15. Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.4 out of 10, Very good, (434 reviews)
"Nice, big building with big, comfy lobby. We were at the end of a long hallway so it was nice and private for us. Woman in charge was very pleasant and competent. Got us checked in right away."
United States
Frederick
The price is CA $110
CA $122 total
includes taxes & fees
Nov 15 - Nov 16
Baymont by Wyndham Chester IL
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

16. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (891 reviews)
"Breakfast was good."
United States
J
The price is CA $112
CA $121 total
includes taxes & fees
Nov 8 - Nov 9
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A row of single-story houses with attached garages, a paved driveway, and a clear sky.

17. Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
Ste Genevieve
8.8 out of 10, Excellent, (681 reviews)
"Great stay and close to all of the things we wanted to do."
United States
Samantha
The price is CA $121
CA $142 total
includes taxes & fees
Nov 15 - Nov 16
Microtel Inn & Suites by Wyndham Sainte Genevieve
A hotel with a modern design, featuring a prominent logo on the building.

18. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
"Had a great stay friendly staff very clean facilities!"
United States
Shannon
The price is CA $119
CA $136 total
includes taxes & fees
Nov 12 - Nov 13
Tru By Hilton Cape Girardeau
A motel with a covered entrance, a flag, and a phone number.

19. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (314 reviews)
"Nice and clean friendly staff"
United States
Bawan
The price is CA $123
CA $134 total
includes taxes & fees
Nov 7 - Nov 8
Madison Inn Lodge
A building with a sign reading "Comfort Suites."

20. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
United States
Jeff
The price is CA $105
CA $114 total
includes taxes & fees
Dec 6 - Dec 7
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Perryville and related destinations

Historic battlefields and the charming downtown district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Centre and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville
A forest of tall pine trees at sunset.

Top reviews in Perryville

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson

10/10 Excellent

Fantastic property! The staff and service were top notch! Definitely our go too place in the area,
Canada
Rodney
Reviewed October 21, 2025
Drury Inn & Suites Jackson MO

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