Perryville Vacation Rentals

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Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Perryville vacation rentals

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

1. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (13 reviews)
"Great place to stay"
United States
Matt
The price is CA $119
CA $240 total
includes taxes & fees
Nov 11 - Nov 12
The Atrium - A Boutique Hotel
A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

2. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is CA $285
CA $439 total
includes taxes & fees
Dec 10 - Dec 11
Urban Lofts
A modern kitchen with dark wood cabinets, a central island, and a brick wall.

3. Downtown Urban Loft #9

Downtown Urban Loft #9
Perryville
10.0 out of 10, Exceptional, (8 reviews)
"The Zen atmosphere made it really relaxing and the spa bathroom was incredible"
United States
Hunter
The price is CA $275
CA $415 total
includes taxes & fees
Nov 16 - Nov 17
Downtown Urban Loft #9
A spacious loft with exposed brick walls, large windows, a kitchen with bar seating, and a ceiling fan.

4. Downtown Urban Loft #1

Downtown Urban Loft #1
Perryville
The price is CA $275
CA $429 total
includes taxes & fees
Nov 11 - Nov 12
Downtown Urban Loft #1
A modern kitchen with stainless steel appliances, a large window, and a breakfast setup on the counter.

5. Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1 review)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is CA $720
CA $1,134 total
includes taxes & fees
Nov 16 - Nov 17
Gorgeous, downtown house!
A bedroom with a bed, a ceiling fan, a window with curtains, and a flat-screen TV on the wall.

6. Charming 3-bedroom Lake House near Perryville

Charming 3-bedroom Lake House near Perryville
Perryville
The price is CA $191
CA $405 total
includes taxes & fees
Nov 16 - Nov 17
Charming 3-bedroom Lake House near Perryville
Exterior

7. Cozy 2-bedroom cottage in charming Ste. Genevieve

Cozy 2-bedroom cottage in charming Ste. Genevieve
Ste. Genevieve
9.8 out of 10, Exceptional, (12 reviews)
"Great location!"
United States
Katie M.
The price is CA $192
CA $228 total
includes taxes & fees
Dec 2 - Dec 3
Cozy 2-bedroom cottage in charming Ste. Genevieve
A white two-story house with a covered porch, a chimney, and a small garden area with chairs and a table.

8. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (296 reviews)
"Absolutely beautiful place to stay!! Very clean!"
United States
Jimmy B.
The price is CA $209
CA $262 total
includes taxes & fees
Nov 24 - Nov 25
Beautiful Modern Loft In Wine Country!
A compact kitchen with a stone floor, a microwave, a stove, and a refrigerator. There are wooden cabinets and a window with blinds.

9. Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake
Murphysboro
10.0 out of 10, Exceptional, (4 reviews)
"Everything was very clean, parking was easy and plenty of room for the truck and boat. Check in was very easy and great contact with very quick responses. Definitely recommend to stay here."
United States
Dustin M.
The price is CA $240
CA $341 total
includes taxes & fees
Nov 24 - Nov 25
Fishing Cabin next to Kinkaid Lake
A hot tub in a covered outdoor area with a view of a swimming pool and a wooden play structure in the background.

10. Charming 2-bedroom country mobile home with game room, hot tub, seasonal pool

Charming 2-bedroom country mobile home with game room, hot tub, seasonal pool
Fredericktown
10.0 out of 10, Exceptional, (15 reviews)
"Host was very kind and every thing we needed was right there . We was to bust with out trip to enjoy the cooking out spot . Highly recommend"
United States
hannah
The price is CA $247
CA $282 total
includes taxes & fees
Nov 14 - Nov 15
Charming 2-bedroom country mobile home with game room, hot tub, seasonal pool
A modern kitchen with grey cabinets, a black refrigerator, and a microwave.

11. "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (32 reviews)
"Very nice stay we enjoyed would definitely stay again"
United States
Ben C.
The price is CA $196
CA $342 total
includes taxes & fees
Nov 16 - Nov 17
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
A hot tub with a wooden deck surrounding it, a window above, and a view of trees outside.

12. Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
Ste. Genevieve
10.0 out of 10, Exceptional, (63 reviews)
"Very comfortable for our party size of 8...and it would have been fine for more as it is advertised for up to 12. It was clean and everything you would need was provided, from towels to toilet paper to air dryer etc. The check-in and check-out process was super simpler and communication from the host was good."
United States
Don D.
The price is CA $381
CA $526 total
includes taxes & fees
Nov 11 - Nov 12
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
A two-story cylindrical building with a covered porch and a welcoming sign.

13. Silo Farm Haus- located in the heart of wine country!

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
10.0 out of 10, Exceptional, (160 reviews)
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
United States
Anthony S.
The price is CA $337
CA $523 total
includes taxes & fees
Nov 14 - Nov 15
Silo Farm Haus- located in the heart of wine country!
A single-story house with a front porch, a garage, and a well-maintained lawn.

14. Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve

Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
Saint Mary
9.8 out of 10, Exceptional, (12 reviews)
"The house was very clean. It's located in a quiet and safe neighborhood. It was well stocked with cooking utensils. It was pet friendly with a secure fenced backyard. The host was responsive and accommodating. We stayed here while we were in town for work and would stay here again."
United States
Deborah H.
The price is CA $179
CA $566 total
includes taxes & fees
Nov 15 - Nov 16
Sleeps 8 | Private Hot Tub + Fenced Yard | Near Historic Ste. Genevieve
A small, single-story building with a porch, a covered outdoor seating area, and a stone foundation.

15. 5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana

5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
Ste. Genevieve
10.0 out of 10, Exceptional, (4 reviews)
"Perfect size cabin to get away and enjoy nature sitting on front porch. Very clean with all the amenities you need. Erin was very nice and prompt response to any of my questions."
United States
Matt H.
The price is CA $268
CA $378 total
includes taxes & fees
Nov 11 - Nov 12
5 Charles Farms Cabin #1 - NEW CABIN - Wineries, Hiking, & Camp Cana
A kitchen with white cabinets, a wooden dining table, a built-in stove, and a trash can.

16. Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.8 out of 10, Exceptional, (37 reviews)
"Super cute house in a great location."
United States
Theresa
The price is CA $152
CA $347 total
includes taxes & fees
Nov 15 - Nov 16
Cozy Three bedroom home in Central Farmington
Interior

17. The Cabin at Charleville

The Cabin at Charleville
Ste. Genevieve
The price is CA $417
CA $529 total
includes taxes & fees
Nov 11 - Nov 12
The Cabin at Charleville
A small, single-story building with a porch, red chairs, and a fan.

18. 5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana

5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
New Offenburg
10.0 out of 10, Exceptional, (2 reviews)
"This was one of the best places I’ve ever stayed. Owner thought of everything and it was so comfortable. The space was perfect, extra blankets, both types of coffee makers, firewood on site. This is a very new property and everything was immaculate and clean. Was easy to navigate check-in and house was so cute! Would definitely recommend to anyone heading to St Gen or any of surrounding areas."
United States
Carole J.
The price is CA $268
CA $378 total
includes taxes & fees
Nov 11 - Nov 12
5 Charles Farms #4 - NEW CABIN - Wineries, Hiking, and Camp Cana
A narrow hallway with a loft bedroom above, a ladder, and a small window.

19. Authentic Train Caboose with Loft & Firepit Near Elephant Rocks

Authentic Train Caboose with Loft & Firepit Near Elephant Rocks
Fredericktown
10.0 out of 10, Exceptional, (4 reviews)
"Our stay was perfect. Tina was a great host, and the caboose was absolutely perfect in every way. The muffins were great. Will definitely plan another visit to this wonderful getaway. Thank you"
United States
Bob A.
The price is CA $339
CA $391 total
includes taxes & fees
Nov 16 - Nov 17
Authentic Train Caboose with Loft & Firepit Near Elephant Rocks
A rural landscape with a red barn, a small white shed, and a dirt road leading to the barn.

20. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is CA $184
CA $282 total
includes taxes & fees
Dec 7 - Dec 8
The Weber Farm - Enjoy a beautiful 100 acre farm!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Perryville Hotel Reviews

A hotel lobby with a reception desk, seating area, and a patterned carpet.
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville

10/10 Excellent

Great Place to Stay! Customer so friendly and nice there!
Canada
Shavanie
Reviewed March 3, 2025
Holiday Inn Express & Suites Perryville by IHG

Find out more about Perryville

Everything you need to know about Perryville vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Perryville vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Perryville vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Perryville vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Perryville. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Perryville vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Perryville vacation rentals we have selected for you start as low as CA $118 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Perryville rentals

At Expedia, we put the best Perryville vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Perryville rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Perryville vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Perryville. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find a vacation rental in Perryville?

Yes, you can find vacation rentals near top local attractions in Perryville, or you can choose a more secluded option if you'd like a relaxing place to stay. Perryville is known for its wineries and golf courses. Make sure you have time to check out the coffeehouses and festivals during your trip.

What are some of the best vacation rentals that Perryville has to offer?

Silo Farm Haus- located in the heart of wine country!: This vacation home rental outside of Perryville is in a rural location and offers a Smart TV to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Perryville?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Perryville stay.

What’s there to see and do in Perryville?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. While here, National Shrine of Our Lady of the Miraculous Medal and Saint Marys Lake are other places worth a visit.

What’s a vacation rental in Perryville like?

Vacation rentals are privately owned properties you can book for short or long periods in Perryville. Vacation rentals offer amenities such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a clean environment, vacation rentals can provide a sense of security away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for family gatherings.