Title: Book The Best Hotels in Old Appleton, MO for 2025 from CA $91 - Competitive Prices - Expedia.ca [Old Appleton Travel Guide](https://expedia.ca/Old-Appleton.dx553248634983492471)[Vacation Rentals in Old Appleton](https://expedia.ca/Old-Appleton-Vacation-Rentals.d553248634983492471.Travel-Guide-VacationRentals)[Old Appleton Car Rentals](https://expedia.ca/Car-Rentals-In-Old-Appleton.d553248634983492471.Car-Rental-Guide)[Old Appleton Vacation Packages](https://expedia.ca/Old-Appleton.d553248634983492471.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Old Appleton, MO from CA $91 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Old Appleton Pool [](https://www.expedia.ca/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=PETS) ## Check prices for these dates Tonight [Nov 12 - Nov 13](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 13 - Nov 14](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471&startDate=2025-11-13&endDate=2025-11-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 54 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville Perryville 8.4/10 Very good (927) "We had a nice stay and they were pet friendly! The front desk staff was very nice and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacquelin CA $94 CA $108 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1009) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $123 CA $130 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG Perryville 9.2/10 Wonderful (527) "Clean room and pleasant staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $133 CA $152 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/12e65c55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/082d2613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 Perryville 6.6/10 (122) "Nice place would recommend Mary Jane’s if you’re looking for good food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $100 CA $114 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (420) "Room was clean and had a refrigerator and microwave for use if needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry CA $95 CA $102 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars)](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (648) "Stayed on our way south for vacation. It was a clean nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel CA $118 CA $128 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/8b8e9c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville Perryville 6.8/10 (415) "Wonderful desk staff, cozy clean beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mckenna CA $98 CA $112 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (90) "It was very nice and close, really loved the cookies and milk highly recommended" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lee CA $122 CA $139 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (673) "Overall was wonderful customer service and breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $81 CA $91 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (738) "Great area, fast check in, quiet, very spacious" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanne CA $121 CA $131 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27®ionId=553248634983492471&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ## More cheap stays in Old Appleton ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St, Perryville, MO CA $133 CA $152 total Nov 16 - Nov 17 includes taxes & fees 9.2/10 Wonderful! (526 reviews) [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway, Cape Girardeau, MO CA $81 CA $91 total Nov 19 - Nov 20 includes taxes & fees 7/10 Good! (665 reviews) [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr, Cape Girardeau, MO CA $122 CA $139 total Nov 30 - Dec 1 includes taxes & fees 9.4/10 Exceptional! (87 reviews) [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr, Perryville, MO CA $94 CA $108 total Nov 19 - Nov 20 includes taxes & fees 8.4/10 Very Good! (925 reviews) [](https://expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Town House Inn 517 E Jackson Blvd, Jackson, MO CA $95 CA $102 total Nov 13 - Nov 14 includes taxes & fees 7.6/10 Good! (420 reviews) [](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Quality Inn Perryville I-55](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Perryville I-55 1517 S. Perryville Blvd., Perryville, MO CA $100 CA $114 total Nov 19 - Nov 20 includes taxes & fees 6.6/10 (122 reviews) [](https://expedia.ca/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ## Hotels in Old Appleton with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/40000000/39930000/39926100/39926011/1b66adae_w.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Old-Appleton-Hotels.s40-0-d553248634983492471.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_w.jpg) 3 Star Hotels 5 properties [](https://expedia.ca/3Star-Old-Appleton-Hotels.s30-0-d553248634983492471.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_w.jpg) 2 Star Hotels 10 properties [](https://expedia.ca/2Star-Old-Appleton-Hotels.s20-0-d553248634983492471.Travel-Guide-Filter-Hotels) ## Recent reviews of Old Appleton hotels ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 5/5 Excellent "Amaiah at the front desk was amazing! She Answered all my questions and double checked that our room was ready since I was a15 minutes early." A verified traveller stayed at Tru By Hilton Cape Girardeau Posted 3 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 5/5 Excellent "One of the cleanest hotel we’ve stayed at. Extremely friendly personnel, starting at the check in counter, to the employees maintaining the breakfast buffet. When traveling, if there’s a Drury Inn & Suites, we’ll be booking with them every time. " A verified traveller stayed at Drury Inn & Suites Jackson MO Posted 5 days ago [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Hot Tub & Creek Views: Secluded Perryville Cabin](//images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/762b23c1_y.jpg) ### Hot Tub & Creek Views: Secluded Perryville Cabin 5/5 Excellent "We were celebrating a 50th birthday and a ladies reunion with life long friends. The location was perfect! Cell service and internet are spotty which made for a perfect unplugged get away. I wish the hot tub had been a little more secure to get in and out of...but at our ages we are extra careful lol Hoping to make this an annual trip! Just watch out for the walnuts!!! Lol" A verified traveller stayed at Hot Tub & Creek Views: Secluded Perryville Cabin Posted 6 days ago [](https://expedia.ca/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 5/5 Excellent "Room was clean and check in was quick and efficient." A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Posted 7 days ago [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](//images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 5/5 Excellent "Clean room and pleasant staff" A verified traveller stayed at Holiday Inn Express & Suites Perryville by IHG Posted 9 days ago [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Town House Inn](//images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 5/5 Excellent "Appears to have been recently remodeled and updated. The room was fairly clean but could use a few cosmetic touches. Staff was courteous. We were only there for one night but this would be a great place to stay for an extended time as it had full kitchen amenities. No breakfast but the cost of the room made up for that. Hardee’s is within walking distance. We would definitely stay here again. " A verified traveller stayed at Town House Inn Posted 9 days ago [](https://expedia.ca/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![The Twisted Sassafras Treehouse ](//images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/55527a20_y.jpg) ### The Twisted Sassafras Treehouse 5/5 Excellent "This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!" A verified traveller stayed at The Twisted Sassafras Treehouse Posted 10 days ago [](https://expedia.ca/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information) ![Beautiful location in the secluded woods ](//images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/193ecf29_y.jpg) ### Beautiful location in the secluded woods 5/5 Excellent "Nestled in the woods, this home is a perfect getaway and a great base for exploring the natural beauty of Southern Illinois! Kevin is an excellent host communicating details for our stay. Great rooms, beds, porch, bath and views to the forest! All super comforable (and exceptionally clean too). I made dinner last night and it was easy to find what I needed in the kitchen. We will definitely come back again!" A verified traveller stayed at Beautiful location in the secluded woods Posted 2 weeks ago [](https://expedia.ca/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ![Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck! ](//images.trvl-media.com/lodging/33000000/32070000/32068400/32068377/725ec117_y.jpg) ### Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck! 5/5 Excellent "House was clean and had everything we needed. Perfect place to stay to enjoy the wineries and relax in the hot tub!! Brian was so helpful and generous and responded promptly to our requests. Great place!! JM" A verified traveller stayed at Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck! Posted 2 weeks ago [](https://expedia.ca/Alto-Pass-Hotels-Rated1-Big-Sky-Cabin-On-The-Wine-Trail-Hot-Tub-FirePit-Pool-Table.h32068377.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Old Appleton? > [La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information), located 17.7 mi (28.5 km) from the heart of Old Appleton, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are [Tru By Hilton Cape Girardeau](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) and [Drury Inn & Suites Jackson MO](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information). See all available [top hotels](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471), or [vacation rentals in Old Appleton](https://www.expedia.ca/Old-Appleton-Vacation-Rentals.d553248634983492471.Travel-Guide-VacationRentals). ### What are some of the best vacation home rentals that Old Appleton has to offer? > [Notting Hill Cottage](https://www.expedia.ca/Alto-Pass-Hotels-Notting-Hill-Cottage.h48991852.Hotel-Information): Visitors like this Old Appleton vacation home rental. It offers a patio, a private yard, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a hot tub. See all [vacation rentals in Old Appleton](https://www.expedia.ca/Old-Appleton-Vacation-Rentals.d553248634983492471.Travel-Guide-VacationRentals). ### If I need to cancel my hotel reservation in Old Appleton, will I receive a refund? > Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=553248634983492471&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Old Appleton. ### What is staying in Old Appleton like? > Visitors to Old Appleton are sure to find plenty to explore and enjoy. There are 54 hotels and other accommodations in the surrounding area. Find out more about [Old Appleton](https://www.expedia.ca/Old-Appleton.dx553248634983492471). ### What should I see while I'm in Old Appleton? > Places to visit in the wider area include [Perryville Country Club](https://www.expedia.ca/Perryville-Country-Club-Perryville.d553248621564822920.Vacation-Attraction), [National Shrine of Our Lady of the Miraculous Medal](https://www.expedia.ca/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Perryville.d553248621561876731.Vacation-Attraction), and [Trail of Tears State Park](https://www.expedia.ca/Trail-Of-Tears-State-Park-Jackson.d553248621532655784.Vacation-Attraction). You'll also find [Missouri's National Veterans Memorial](https://www.expedia.ca/Missouris-National-Veterans-Memorial-Perryville.d620724250067501056.Vacation-Attraction) and [Indian Creek Wild Area](https://www.expedia.ca/Indian-Creek-Wild-Area-Jackson.d911405814471028736.Vacation-Attraction) in the area. Check out what more to see and do in Expedia's [Old Appleton guide](https://www.expedia.ca/Old-Appleton.dx553248634983492471). ### What's the weather like in Old Appleton? > The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Old Appleton is 56 inches. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Advance Hotels](https://www.expedia.ca/Advance-Hotels.d553248634983475122.Travel-Guide-Hotels) - [Belgique Hotels](https://www.expedia.ca/Belgique-Hotels.d553248635975859150.Travel-Guide-Hotels) - [Benton Hotels](https://www.expedia.ca/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Blodgett Hotels](https://www.expedia.ca/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomsdale Hotels](https://www.expedia.ca/Bloomsdale-Hotels.d3000444549.Travel-Guide-Hotels) - [Cabin Rentals in Brazeau Township](https://www.expedia.ca/Brazeau-Township-Cabins.d553248635976430617-aaCabins.Travel-Guide-Accommodation) - [Rv Parks in Cape Girardeau County](https://www.expedia.ca/Cape-Girardeau-County-RV-Parks.d553248635976430467-aaRVParks.Travel-Guide-Accommodation) - [All Inclusive Resorts and in Cape Girardeau](https://www.expedia.ca/Cape-Girardeau-Hotels-All-Inclusive-Hotel.0-0-d820-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)