Book The Best Hotels in Old Appleton, MO for 2026 from CA $96 - Fully Refundable Options

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Our top choices for Old Appleton hotels

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

1. Drury Inn & Suites Jackson MO

Jackson

Debra S

CA $114

CA $120 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

2. Super 8 by Wyndham Perryville

Perryville

paulette

CA $98

CA $112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

A hotel lobby with a seating area, a reception desk, and a bar.

3. Holiday Inn Express & Suites Perryville by IHG

Perryville

Lisa

CA $144

CA $164 total

includes taxes & fees

Nov 1 - Nov 2

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

CA $115

CA $124 total

includes taxes & fees

Nov 1 - Nov 2

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

5. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

CA $127

CA $145 total

includes taxes & fees

Oct 14 - Oct 15

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

6. Days Inn by Wyndham Perryville

Perryville

"When renting a motel room under 100 bucks you have to remember, you’re not at the Hilton. This is an aging building although it has been kept up, the bed was comfortable. I slept well. The shower was fantastic and plenty of hot water super easy access and parking . The continental breakfast was better than expected. Air conditioning. Heat worked fine and the place was really quiet. They probably could do a little better job with the coffee, just my opinion."

Jeffrey

CA $96

CA $110 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

7. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

CA $108

CA $116 total

includes taxes & fees

Oct 29 - Oct 30

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

8. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

CA $91

CA $104 total

includes taxes & fees

Nov 1 - Nov 2

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

9. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

CA $85

CA $96 total

includes taxes & fees

Nov 1 - Nov 2

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a sign that reads "The Atrium Boutique Hotel".

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

10. The Atrium - A Boutique Hotel

Perryville

Brian

CA $107

CA $227 total

includes taxes & fees

Oct 8 - Oct 9

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

11. Perryville RV Resort

Perryville

Kevin

CA $94

CA $108 total

includes taxes & fees

Oct 14 - Oct 15

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

12. Urban Lofts

Perryville

Grace

CA $286

CA $442 total

includes taxes & fees

Oct 9 - Oct 10

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A room with a white door, a radiator, a blue carpet, and a mural on the wall.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

13. The Mediterranean House 1858

Perryville

CA $665

CA $1,100 total

includes taxes & fees

Oct 15 - Oct 16

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Top Old Appleton Hotel Reviews

The Twisted Sassafras Treehouse

10/10 Excellent

"What a perfect place to celebrate our 1st year wedding anniversary! Beautiful treehouse and very well thought out. Great first time experience. And out of the way yet close to Cape access to restaurants and entertainment if you choose. Will definitely recommend to others"

Drury Inn & Suites Jackson MO

10/10 Excellent

"We were only there for one night, but we SO grateful for a clean, safe and lovely stay! Would recommend it highly!"

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Nice place! Good breakfast!!"

Days Inn by Wyndham Perryville

8/10 Good

Hot Tub & Creek Views: Secluded Perryville Cabin

10/10 Excellent

"Wonderful location with the necessities to enjoy your time without taking away from the beauty of where you are"

Beautiful location in the secluded woods

8/10 Good

"It was good, except the A/C was in the living room and you need to keep the bedroom doors open to get the air."

Big Sky Cabin! Hot Tub! Fire Pit! Pool Table! Private! Can hold Large Groups

10/10 Excellent

"Beautiful home with a great game room. Close to wineries with a private setting. Perfect getaway."

Urban Lofts

10/10 Excellent

"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

More cheap stays in Old Appleton

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

CA $85

CA $96 total

Nov 1 - Nov 2

includes taxes & fees

Days Inn by Wyndham Perryville

1500 Liberty Street Perryville MO

CA $96

CA $110 total

Oct 11 - Oct 12

includes taxes & fees

7/10 Good! (458 reviews)

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

CA $98

CA $112 total

Nov 1 - Nov 2

includes taxes & fees

Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd Jackson MO

CA $108

CA $116 total

Oct 29 - Oct 30

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

CA $127

CA $145 total

Oct 14 - Oct 15

includes taxes & fees

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

CA $151

CA $173 total

Nov 4 - Nov 5

includes taxes & fees

9.2/10 Wonderful! (633 reviews)

Hotels in Old Appleton with star rating

Frequently asked questions

When is the best time to go to Old Appleton?

The best time to visit Old Appleton, Missouri, is during the spring (April to early June) and autumn (September to October) months.These seasons offer pleasant weather, with moderate temperatures and lower humidity, making outdoor activities and exploring the area's natural beauty much more enjoyable. Spring brings blooming wildflowers and lush greenery, while autumn showcases stunning fall foliage.Couples looking for a romantic getaway will appreciate the comfortable conditions for strolls along the Apple Creek or exploring local vineyards without the intense heat of summer. The crisp air and picturesque scenery in spring and autumn create a lovely backdrop for a relaxed trip.For those interested in history and local culture, these seasons also often coincide with various community events and festivals, providing a deeper insight into Old Appleton's heritage.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Old Appleton.

How much is the nightly rate at a Old Appleton hotel?

Prices for hotels in Old Appleton often vary, but you can find a great deal from CA $96 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Book Hotels in Old Appleton on Expedia.com

Find hotels in Old Appleton, MO from CA $96

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Old Appleton

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Old Appleton hotels

1. Drury Inn & Suites Jackson MO

2. Super 8 by Wyndham Perryville

3. Holiday Inn Express & Suites Perryville by IHG

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

5. Tru By Hilton Cape Girardeau

6. Days Inn by Wyndham Perryville

7. Comfort Suites Jackson-Cape Girardeau

8. Quality Inn Perryville I-55

9. Quality Inn Cape Girardeau North

10. The Atrium - A Boutique Hotel

11. Perryville RV Resort

12. Urban Lofts

13. The Mediterranean House 1858

Top Old Appleton Hotel Reviews

The Twisted Sassafras Treehouse

Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Perryville by IHG

Days Inn by Wyndham Perryville

Hot Tub & Creek Views: Secluded Perryville Cabin

Beautiful location in the secluded woods

Big Sky Cabin! Hot Tub! Fire Pit! Pool Table! Private! Can hold Large Groups

Urban Lofts

More cheap stays in Old Appleton

Quality Inn Cape Girardeau North

Days Inn by Wyndham Perryville

Super 8 by Wyndham Perryville

Comfort Suites Jackson-Cape Girardeau

Tru By Hilton Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Hotels in Old Appleton with star rating

Frequently asked questions

Explore a world of travel with Expedia

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