Ohio River Valley Vacation Packages

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    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Top Ohio River Valley Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Virgin Hotels Chicago

Virgin Hotels Chicago

4.5 out of 5
Downtown Chicago
Save 100% on your flight
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip non-stop flight included
Hamilton (YHM) to Chicago (ORD)
9.2/10 Wonderful! (1,334 reviews)
I loved the location of the property, and the overall concept of something fun and funky, but I had a "higher end" room, and it was right near the elevator, so I got a lot of noise on that side, plus the El from the other side. The rug wasn't super clean (although the bedding and the rest of the room were a delight). The most annoying thing was the TV. Anything I turned it to, 10 minutes later to the minute, it went back to the Virgin channel #1, here are all our hotels in the world. I really hated having to stay on top of a show, when usually I want the tv on as background while I'm getting ready, etc. Also, this hotel's amenities were oversold, i.e., good luck getting on the rooftop, especially if you just wanted a quiet sip of a drink. I loved the cafe and the staff, though, everyone was very pleasant.

Reviewed on Jul. 15, 2025

Trump International Hotel & Tower Chicago

Trump International Hotel & Tower Chicago

5 out of 5
Downtown Chicago
Save 100% on your flight
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip non-stop flight included
Hamilton (YHM) to Chicago (ORD)
9.4/10 Exceptional! (1,635 reviews)
Amazing customer service

Reviewed on Jul. 13, 2025

Park Hyatt Chicago

Park Hyatt Chicago

5 out of 5
Downtown Chicago
Save 100% on your flight
per person
Sep 18 - Sep 21
found 1 day ago
Roundtrip flight included
Toronto (YTO) to Chicago (ORD)
9.6/10 Exceptional! (1,000 reviews)
Superb customer service, clean hotel!

Reviewed on Jun. 13, 2025

Level Chicago - River North

Level Chicago - River North

4 out of 5
Downtown Chicago
Save 100% on your flight
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip non-stop flight included
Hamilton (YHM) to Chicago (ORD)
9/10 Wonderful! (639 reviews)
Amazing amenities. friendly staff and clean rooms. Views from the balcony were so nice!

Reviewed on Jul. 12, 2025

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton

4 out of 5
Downtown Chicago
Save 100% on your flight
per person
Sep 4 - Sep 9
found 1 day ago
Roundtrip non-stop flight included
Hamilton (YHM) to Chicago (ORD)
9.4/10 Exceptional! (2,053 reviews)
Wonderful views from navy pier.

Reviewed on Jul. 14, 2025

Where to stay in Ohio River Valley

Find the best Ohio River Valley areas and neighborhoods for the activities you enjoy most. Learn more about Ohio River Valley
Central Canal which includes landscape views, a river or creek and a city

Downtown Indianapolis

1 out of top 10 points of interest in this area
4.5/5(57 area reviews)

As the city's cultural, political, and economic hub, this neighborhood boasts historic districts, performing arts venues, and museums. Enjoy nightlife on Meridian Street and Massachusetts Avenue, or stroll along the Indianapolis Canal Walk.

Find hotels in Downtown Indianapolis

Ready to book your vacation to Ohio River Valley?

 

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Ohio River Valley Hotel Deals

Radisson Hotel Cincinnati Riverfront

Radisson Hotel Cincinnati Riverfront

3.5 out of 5
668 W 5th St, Covington, KY
The price is CA $185 per night from Jul 27 to Jul 28
CA $185
CA $208 total
Jul 27 - Jul 28
includes taxes & fees
7/10 Good! (2,072 reviews)
"Very nice stay. Thank you"

Reviewed on Jul. 12, 2025

Radisson Hotel Cincinnati Riverfront
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
The price is CA $194 per night from Aug 10 to Aug 11
CA $194
CA $228 total
Aug 10 - Aug 11
includes taxes & fees
8.8/10 Excellent! (3,445 reviews)
"Downtown location. Beautiful room!"

Reviewed on Jul. 12, 2025

Galt House Hotel Trademark Collection by Wyndham
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

4 out of 5
35 W 5th St, Cincinnati, OH
The price is CA $169 per night from Jul 20 to Jul 21
CA $169
CA $202 total
Jul 20 - Jul 21
includes taxes & fees
7.8/10 Good! (1,036 reviews)
"Check in was quick and easy, staff at front desk are very friendly. Room was clean and spacious. Beds were soft and comfortable. Plenty of pillows provided. Plenty of provided toiletries & towels in bathroom. Easy walk to fountain square or the Reds stadium."

Reviewed on Jul. 13, 2025

Hilton Cincinnati Netherland Plaza
See all 19,405 properties in Ohio River Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Ohio River Valley

Ark Encounter

Ark Encounter

5/5(27 reviews)

Have a fun-filled day at Ark Encounter and see why people love this amusement park in Williamstown. Discover the restaurants and museums in this walkable area.

Ark Encounter
Kings Island showing rides and a sporting event

Kings Island

5/5(2 reviews)

This award-winning amusement and water park in Mason has more than 80 thrilling rides and attractions.

Kings Island
Purdue University

Purdue University

4.5/5(2 reviews)

Walk around the campus of Purdue University, a top college in West Lafayette. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

Purdue University

Frequently asked questions

How much does an Ohio River Valley vacation package cost?
We make it simple to see the world, with Ohio River Valley packages starting from as low as CA $1,026. You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add a few tours and activities to your travel itinerary?
How do I get a cheap travel package to Ohio River Valley?
Bundle your flight and hotel bookings, add on extras such as activities, and save with an Ohio River Valley vacation package. You won't just score superb discounts on your getaway --- you'll have loads of choice at your fingertips too. When you book through Expedia, you can choose from more than 550 airlines and 1,000,000 hotels across the globe. Your next grand adventure begins right here, right now!
Where should I stay in Ohio River Valley?
Indianapolis is a wonderful city to include in your itinerary. Here, you'll find popular sights including Indianapolis Motor Speedway and Lucas Oil Stadium. Columbus also draws in many globetrotters eager to explore some of the best attractions in Ohio River Valley. Included in these are Ohio State University and Ohio Stadium.
What are the top hotels in Ohio River Valley?
Sheraton Indianapolis Hotel at Keystone Crossing and Radisson Hotel Louisville Jeffersonville know how to make their guests feel welcome in Indianapolis. If you also plan to explore Louisville, have a look at Omni Louisville Hotel and La Quinta Inn & Suites by Wyndham Cincinnati Airpt Florence. Both are top picks with travelers.
How far in advance should I book my Ohio River Valley vacation?
Reserving your tickets early with Expedia means one less thing to worry about. Most air carriers advertise prices up to 12 months prior to take off. This is often the cheapest time to book. If circumstances have left you booking late, discount flights to Ohio River Valley are still known to appear a few weeks before departure.
What does an Expedia Ohio River Valley travel package include?
Much of that is up to you. You can pick from a range of Ohio River Valley bundles, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a rental car with a flight. Once you've made your booking, you can add on the fun stuff like experiences and tours. Whatever your dream Ohio River Valley break looks like, you're sure to save!
What should I know before booking an Ohio River Valley travel package?
Locking in all the parts of your trip together is a terrific way to save. Bundle your car rentals, airfares and hotels into a handy little package. But your options don't end at hotels. Expedia features all types of properties, including vacation rentals like oceanfront condos and city residences. The list is almost endless!
Can I choose my airline with an Ohio River Valley Expedia vacation package?
Yes, of course. Expedia has access to more than 550 partner airlines all over the world, so choose the carrier that's a good fit for your budget and travel needs.
If I'm not able to travel, can I cancel my Ohio River Valley vacation package?
Whether it's your flight or hotel, yes, you can amend or cancel it. Locked in your Ohio River Valley vacation package in the last 24 hours? You may be able to make changes or cancellations for free. If it's been longer than that, you may be charged a fee by your airline, hotel or car rental company. For further information, check out our Customer Service Portal. We'll help you every step of the way.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.