Title: La Mesa Vacation Rentals from CA $190: Short-Term Rentals for 2026 | Expedia.ca [Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # La Mesa Vacation Rentals - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-01-30&endDate=2026-02-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesa vacation rentals ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/52aafcdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/223e016d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/85cb7ac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121820000/121817600/121817509/c5c93f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage in Mount Helix [](https://www.expedia.ca/La-Mesa-Hotels-Mediterranean-Inspired-1BR-Guesthouse-Full-Kitchen.h121817509.Hotel-Information) CA $166 CA $426 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/La-Mesa-Hotels-Mediterranean-Inspired-1BR-Guesthouse-Full-Kitchen.h121817509.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/c0a3b2e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/w6012h4016x0y0-36206196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/1d733067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123280000/123270200/123270168/d875217e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Mount Helix [](https://www.expedia.ca/La-Mesa-Hotels-New-Modern-2BR-Home-With-Movie-Theater.h123270168.Hotel-Information) [](https://www.expedia.ca/La-Mesa-Hotels-New-Modern-2BR-Home-With-Movie-Theater.h123270168.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/7f0c02f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/ef0e899c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, table tennis](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/15d82ae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, table tennis](https://images.trvl-media.com/lodging/110000000/109720000/109718900/109718812/dca5b67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in La Mesa [](https://www.expedia.ca/La-Mesa-Hotels-SDSUDowntown-10-Min-GameRoom-Fire-Pit-Free-Parking-Easy-Freeway-Access.h109718812.Hotel-Information) 8.4/10 Very good (6 reviews) "We stayed at this beautiful VRBO for our child’s college graduation in San Diego, and it couldn’t have been more perfect. The home was spotless, spacious, and exactly as described—if not better! Every room was thoughtfully appointed, and the beds were incredibly comfortable. The kitchen had everything we needed to cook family meals, and we loved gathering in the common areas to celebrate and relax.The location was ideal—close to the campus and shopping.Our host was responsive, welcoming, and... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele G. CA $238 CA $555 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/La-Mesa-Hotels-SDSUDowntown-10-Min-GameRoom-Fire-Pit-Free-Parking-Easy-Freeway-Access.h109718812.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/f7600228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/519d5bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/1acf123e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, books, music library](https://images.trvl-media.com/lodging/123000000/122950000/122947400/122947388/6fc7575b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in La Mesa [](https://www.expedia.ca/La-Mesa-Hotels-4BR3Bth-King-Bed.h122947388.Hotel-Information) CA $139 CA $512 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/La-Mesa-Hotels-4BR3Bth-King-Bed.h122947388.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/3f30927d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/08904848.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/c540c1b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123270000/123265200/123265181/c54c9ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Mount Helix [](https://www.expedia.ca/La-Mesa-Hotels-La-Mesa-New-3BR-Oasis-With-Pool-And-Games.h123265181.Hotel-Information) CA $191 CA $678 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/La-Mesa-Hotels-La-Mesa-New-3BR-Oasis-With-Pool-And-Games.h123265181.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/db3a0fed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/5efb1585_edited_2105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/w4030h3024x0y0-ff0a1872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105390000/105380700/105380638/5d897517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Mount Helix [](https://www.expedia.ca/La-Mesa-Hotels-An-Elegant.h105380638.Hotel-Information) 9.0/10 Wonderful (2 reviews) "We love a simple no-nonsense place and this was perfect for us. The host is very responsive and was constantly checking in with us on what else we need to be comfortable to stay here. The area is close a lot of nice restaurants so that was a plus. We would love to stay here next time we visit San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darakhshan T. CA $313 CA $410 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/La-Mesa-Hotels-An-Elegant.h105380638.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/121000000/120770000/120768900/120768808/4ec2d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120770000/120768900/120768808/c92597fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120770000/120768900/120768808/c891cade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/121000000/120770000/120768900/120768808/207dc3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa in Mount Helix [](https://www.expedia.ca/La-Mesa-Hotels-Luxury-5BR-Villa-Pool.h120768808.Hotel-Information) [](https://www.expedia.ca/La-Mesa-Hotels-Luxury-5BR-Villa-Pool.h120768808.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/c76425ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b4a5f1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Downtown San Diego [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) 9.2/10 Wonderful (629 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KELLY CA $164 CA $231 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Room, 1 Queen Bed (East - Freeway Facing)](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Hillcrest [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) 8.4/10 Very good (271 reviews) "Overall good place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaac CA $140 CA $158 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/aa1995cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/333bf268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Middletown [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) 9.6/10 Exceptional (108 reviews) "would definitely go back and stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kounwick CA $127 CA $190 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/123000000/122440000/122437500/122437453/a88f938d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, stovetop](https://images.trvl-media.com/lodging/123000000/122440000/122437500/122437453/45b339ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/123000000/122440000/122437500/122437453/25862993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122440000/122437500/122437453/760ec532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bay Terraces [](https://www.expedia.ca/San-Diego-Hotels-Soothing-Studio-With-AC-In-Sunny-San-Diego.h122437453.Hotel-Information) 10/10 Exceptional (1 review) "Everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosa G. CA $145 CA $191 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/San-Diego-Hotels-Soothing-Studio-With-AC-In-Sunny-San-Diego.h122437453.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/41d1b5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/02c10b6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/108847dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/109000000/108600000/108593500/108593412/170fbed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Encanto [](https://www.expedia.ca/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information) 8.6/10 Excellent (31 reviews) "The plsce was pretty beat up, in a not great neighborhood. Thought it wasn’t worth the money." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol L CA $111 CA $312 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/San-Diego-Hotels-Ted-2-Bedroom-Cozy-House-In-Central-Location-10-Minutes-To-Balboa.h108593412.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103730000/103725100/103725013/51e419f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, stereo](https://images.trvl-media.com/lodging/104000000/103730000/103725100/103725013/01754d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/104000000/103730000/103725100/103725013/7f1e98e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103730000/103725100/103725013/468f40ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Mid-City [](https://www.expedia.ca/San-Diego-Hotels-2BR-House-In-Central-San-Diego.h103725013.Hotel-Information) 9.6/10 Exceptional (9 reviews) "Our visit was short but really enjoyed our stay. Definitely will stay here again when traveling with family or friends. Place was clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle M. CA $150 CA $451 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/San-Diego-Hotels-2BR-House-In-Central-San-Diego.h103725013.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/w1199h799x1y1-12fbdf79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/w1200h798x0y1-5e4069e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/882b7878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/108000000/107770000/107764300/107764239/36e9744e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Spring Valley [](https://www.expedia.ca/Spring-Valley-Hotels-Modern-Lakeview-Studio-W-Patio.h107764239.Hotel-Information) 7.4/10 Good (6 reviews) "It was beautiful and very modern. We loved it and hope to come back again!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronette B. CA $99 CA $262 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Spring-Valley-Hotels-Modern-Lakeview-Studio-W-Patio.h107764239.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/f291ebe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/02e6515e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/c50c50bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Non Smoking, Kitchenette | Living area](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/c8678e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Del Mar [](https://www.expedia.ca/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information) 9.2/10 Wonderful (147 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin CA $294 CA $379 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/834f95c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | In-room dining](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/3636bd40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/bc47b23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/f68e9f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Downtown San Diego [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) 8.0/10 Very good (154 reviews) "Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Beach towels](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/a981e220.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/e03e7f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/e3ba4b42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93250000/93245900/93245882/df13d4b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Bay Ho [](https://www.expedia.ca/San-Diego-Hotels-Adorable-1-Bedroom-House-8-Minutes-From-La-Jolla.h93245882.Hotel-Information) 10/10 Exceptional (44 reviews) "The property is centrally located to everything we were doing. Perfect for a couple. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy N. CA $193 CA $349 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/San-Diego-Hotels-Adorable-1-Bedroom-House-8-Minutes-From-La-Jolla.h93245882.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/176e7c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/37bf8b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/ae7c0c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/46a9ae00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Historic Downtown Coronado [](https://www.expedia.ca/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) 9.0/10 Wonderful (756 reviews) "Wonderful stay. Best room and great location. Staff were wonderful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn CA $280 CA $308 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/108000000/107730000/107726300/107726247/94819867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107730000/107726300/107726247/620ab878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107730000/107726300/107726247/5d57c450.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/108000000/107730000/107726300/107726247/b8b9440c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Encanto [](https://www.expedia.ca/San-Diego-Hotels-5bed3ba.h107726247.Hotel-Information) 10/10 Exceptional (3 reviews) "We enjoyed our experience and grateful for this time here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lowlan B. CA $276 CA $935 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/San-Diego-Hotels-5bed3ba.h107726247.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107910000/107901900/107901894/0531a6db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107910000/107901900/107901894/41f08f3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107910000/107901900/107901894/0f20b07c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/108000000/107910000/107901900/107901894/22713a63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation Home in Grant Hill [](https://www.expedia.ca/San-Diego-Hotels-Modern-Eclectic-1BR-By-Downtown.h107901894.Hotel-Information) 10/10 Exceptional (1 review) "The apartment was good in a little secure compound gated. The area aroun the place was a little trashy. There's a small grocery store across the street thats really the only thing close it is anout a mile to the trolley station. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dan T. CA $107 CA $274 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Eclectic-1BR-By-Downtown.h107901894.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-26&endDate=2026-01-27®ionId=8484&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals) ## Top La Mesa Hotel Reviews ![Manchester Grand Hyatt San Diego](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/91e2517e_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Wonderful place" [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "The staff was courteous and helpful. The room was perfect for a short weekend. I loved all the green space to walk my dogs. " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "The room clean, the area safe and the staff friendly " [](https://expedia.ca/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "I really enjoyed the easy parking and the friendly staff who accommodated my request for a downstairs room because I was traveling with a child. One small thing I missed was having a hot cup of coffee in the morning; the drip machine was out of order, and I noticed many used cups left behind, which made it a bit less convenient. I mentioned it to the front desk, and they were aware of the issue. It might be helpful if a sign were posted or the machine were temporarily removed when it’s not working, but overall, this is a warm and family-friendly place that I would recommend." [](https://expedia.ca/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "We stayed at Days Inn San Diego for 3 days with our family and had a pleasant experience overall. One of the biggest advantages for us was the room with a kitchen option, which made traveling with family much easier. Being able to prepare simple meals and snacks saved time and money. The room was clean, spacious, and functional. While the property is not luxury and feels a bit dated, everything worked well and met our needs for a family stay. Beds were comfortable, and the kitchen had the basic essentials needed for a short trip. The location is convenient, with easy access to major attractions, restaurants, and highways around San Diego. Parking was available and hassle-free, which is important when traveling with kids. Staff were friendly and helpful, and check-in/check-out was smooth. Breakfast options were basic, but having the kitchen made up for it. Overall, Days Inn San Diego is a good budget-friendly option for families, especially if you want a kitchen and plan to spend most of your time exploring the city. We would consider staying again for a short family trip." [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Embassy Suites by Hilton San Diego Bay Downtown](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/cfe599b5_y.jpg) ### Embassy Suites by Hilton San Diego Bay Downtown 10/10 Excellent "Very easy vacation, convenient breakfast as well as location." [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-Bay-Downtown.h5328.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Can room" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "都很好" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Loved the location and so nice!" [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ## Find out more about La Mesa You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with La Mesa. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in La Mesa ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - 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[Vacation Homes in La Mesa ](https://expedia.ca/La-Mesa-Private-Vacation-Homes.d8484-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in La Mesa ](https://expedia.ca/La-Mesa-Apartments.d8484-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in La Mesa ](https://expedia.ca/La-Mesa-Condos.d8484-aaCondos.Travel-Guide-Accommodation) - [Cottages in La Mesa ](https://expedia.ca/La-Mesa-Cottages.d8484-aaCottages.Travel-Guide-Accommodation) - [Villas in La Mesa ](https://expedia.ca/La-Mesa-Villas.d8484-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in La Mesa ](https://expedia.ca/La-Mesa-Guest-Houses.d8484-aaGuestHouses.Travel-Guide-Accommodation) - [Resorts in La Mesa ](https://expedia.ca/La-Mesa-Resort-Hotels.d8484-aaResortHotels.Travel-Guide-Accommodation) - [Aparthotels in La Mesa ](https://expedia.ca/La-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation) - [Motels in La Mesa ](https://expedia.ca/La-Mesa-Motels.d8484-aaMotels.Travel-Guide-Accommodation) - [Hostels in La Mesa ](https://expedia.ca/La-Mesa-Hostels.d8484-aaHostels.Travel-Guide-Accommodation) - [Cabin Rentals in La Mesa ](https://expedia.ca/La-Mesa-Cabins.d8484-aaCabins.Travel-Guide-Accommodation) - [B&B in La Mesa ](https://expedia.ca/La-Mesa-Bed-And-Breakfast.d8484-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Farmstay in La Mesa ](https://expedia.ca/La-Mesa-Agritourism.d8484-aaAgritourism.Travel-Guide-Accommodation) - [RV Parks in La Mesa ](https://expedia.ca/La-Mesa-RV-Parks.d8484-aaRVParks.Travel-Guide-Accommodation) - [Houseboats in La Mesa ](https://expedia.ca/La-Mesa-Houseboats.d8484-aaHouseboats.Travel-Guide-Accommodation) - [Inns in La Mesa ](https://expedia.ca/La-Mesa-Inns.d8484-aaInns.Travel-Guide-Accommodation) - [Residences in La Mesa ](https://expedia.ca/La-Mesa-Residences.d8484-aaResidences.Travel-Guide-Accommodation) - [Castles in La Mesa ](https://expedia.ca/La-Mesa-Castles.d8484-aaCastles.Travel-Guide-Accommodation) ## Frequently asked questions ### Are there vacation rentals in La Mesa? ### What are some of the best vacation rentals that La Mesa has to offer? ### How many vacation rentals are there in La Mesa? ### What can I see and do in La Mesa? ### What are vacation rentals like in La Mesa? ### Expedia's Latest Trends Hotels - 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