Title: Hotels by Ayres Collection in La Mesa from CA $149 | Expedia.ca [La Mesa Travel Guide](https://expedia.ca/La-Mesa.dx8484)[Hotels in La Mesa](https://expedia.ca/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d8484.Travel-Guide-VacationRentals)[Flights to La Mesa](https://expedia.ca/Cheap-Flights-To-La-Mesa.d8484.Travel-Guide-Flights)[Things to do in La Mesa](https://expedia.ca/Things-To-Do-In-La-Mesa.d8484.Travel-Guide-Activities)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d8484.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d8484.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/4f7cd2ecead0197821ab65005d48bfd4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Michele Butts # Find Hotels by Ayres Collection in La Mesa from CA $149 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=8484&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top La Mesa Ayres Collection Hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/089f0b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/8fd57751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/315ec7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/60000/50100/50032/8aabd9fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ayres Lodge Alpine Alpine 9.2/10 Wonderful (1017) "Great stay" CA $137 CA $149 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Alpine-Hotels-Ayres-Lodge-Alpine.h50032.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3ced364d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3c739431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/ff230e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/69474629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ayres Hotel San Diego South - Chula Vista Otay Ranch 9.8/10 Exceptional (1096) "The staff were friendly, clean rooms, and conveniently located to shops and places to eat " CA $192 CA $212 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=8484&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels-Ayres-Collection.0-0-d8484--bAyresCollection.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels-Ayres-Collection.0-0-d8484--bAyresCollection.Travel-Guide-Filter-Hotels) ## Top La Mesa Hotel Reviews ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Scenic balcony view was great" [](https://expedia.ca/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Everything was great " [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Very Convenient being a few blocks away from little italy and then the metro station was right there too!" [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Nice staff.! " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Palihotel San Diego Gaslamp Quarter](//images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef_y.jpg) ### Palihotel San Diego Gaslamp Quarter 10/10 Excellent "Staff was great location was great" [](https://expedia.ca/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Very clean, easy to move a lot things to do and Tourist Really love it" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Great location for the gaslamp" [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Nice stay" [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Loved the location & ease of access to the city." 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[Scuba Diving Hotels in Windsor Hills](https://www.expedia.ca/Windsor-Hills-La-Mesa-Hotels-Scuba-Diving-Vacations.0-n553248635976482085-0-tscubadivingvacations.Travel-Guide-Filter-Hotels) - [Flights to Lemon Grove](https://www.expedia.ca/Cheap-Flights-To-Lemon-Grove.d177690.Travel-Guide-Flights) - [Flights to San Diego](https://www.expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights) - [Flights to Spring Valley](https://www.expedia.ca/Cheap-Flights-To-Spring-Valley.d177858.Travel-Guide-Flights) - [Flights from Lemon Grove](https://www.expedia.ca/lp/flights/177690/flights-from-lemon-grove) - [Flights from Spring Valley](https://www.expedia.ca/lp/flights/177858/flights-from-spring-valley) - [Flights from Vancouver (YVR) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yvr/san/vancouver-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (SAN)](https://www.expedia.ca/lp/flights/yyz/san/toronto-to-san-diego) - [Visit Mount Helix](https://www.expedia.ca/La-Mesa-Mount-Helix.dx553248635976474371) - [Visit Lemon Grove](https://www.expedia.ca/Lemon-Grove.dx177690) - [Visit Lake Murray](https://www.expedia.ca/San-Diego-Lake-Murray.dx553248635976470862) - [Visit Rolando Village](https://www.expedia.ca/San-Diego-Rolando-Village.dx553248635976471982) - [Car rental Lemon Grove](https://www.expedia.ca/Car-Rentals-In-Lemon-Grove.d177690.Car-Rental-Guide) - [Car rental Spring Valley](https://www.expedia.ca/Car-Rentals-In-Spring-Valley.d177858.Car-Rental-Guide) - [Book Ayres Collection in La Mesa on Expedia.com](https://www.expedia.com/La-Mesa-Hotels-Ayres-Collection.0-0-d8484--bAyresCollection.Travel-Guide-Filter-Hotels)