Title: Florida Keys Guest Houses | Expedia.ca [Florida Keys Travel Guide](https://expedia.ca/Florida-Keys.dx6023765)[Hotels in Florida Keys](https://expedia.ca/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels)[Vacation Rentals in Florida Keys](https://expedia.ca/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)[Flights to Florida Keys](https://expedia.ca/Cheap-Flights-To-Florida-Keys.d6023765.Travel-Guide-Flights)[Things to do in Florida Keys](https://expedia.ca/Things-To-Do-In-Florida-Keys.d6023765.Travel-Guide-Activities)[Florida Keys Car Rentals](https://expedia.ca/Car-Rentals-In-Florida-Keys.d6023765.Car-Rental-Guide)[Florida Keys Vacation Packages](https://expedia.ca/Florida-Keys.d6023765.Destination-Travel-Guides) ![Higgs Beach which includes a beach and tropical scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63798-Florida-Keys.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in Florida Keys ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6023765&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6023765&startDate=2025-10-31&endDate=2025-11-02&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6023765&startDate=2025-11-14&endDate=2025-11-16&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6023765&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Florida Keys Guest Houses ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b0a43673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b442c959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/67c8f76f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b27f4d1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ragged Edge Resort & Marina Islamorada 9.4/10 Exceptional (195) "The location was quiet and relaxing. We never heard a peep out of any of the other guests and it seemed that they were up early and in bed early which left us to enjoy the hotel grounds later in the evening... We had the pool to ourselves the entire week. Pretty view of the ocean. Close to everything you'll need or want including great restaurants and convenience stores. The staff was helpful and kind and we would def go back for a restful vacation. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Cassidy CA $153 CA $172 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Islamorada-Hotels-Ragged-Edge-Resort-Marina.h56952622.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/300/217/c6778dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/300/217/dc75eb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/300/217/8e70662e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic King Balcony](https://images.trvl-media.com/lodging/1000000/10000/300/217/af12ee69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amsterdam's Curry Mansion Inn Key West Historic District 8.4/10 Very good (1004) "Right in the middle of everything yet quiet at night. Beautiful room and helpful staff via text. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly CA $193 CA $360 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Amsterdams-Curry-Mansion-Inn.h217.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/f87deff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/3120319b_edited_07ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/52bdb78e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds | Living area](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/78fb0a25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Habitation Guest House Key West Historic District 9.4/10 Exceptional (903) "Great room and very nice staff. I would highly recommend this hotel. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $150 CA $169 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-LHabitation-Guest-House.h9013816.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/77f11bb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/2f1f2895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/eb10500d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![NYAH Private Balcony Room 6 Single Beds | Balcony view](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/a350e3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NYAH Key West - Adults Only Key West Historic District 7.8/10 Good (1006) "Nice place, perfect location for getting around on foot. " ![](https://a.travel-assets.com/egds/marks/flags/mx.svg) Jose CA $138 CA $218 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Key-West-Hotels-NYAH-Key-West-Adults-Only.h7500588.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/a2bf0992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/46602c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/ba6b4821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 Queen Bed, City View, Annex Building | Private kitchen](https://images.trvl-media.com/lodging/111000000/110490000/110488200/110488130/c002f8c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Douglas House Old Town Key West 9.6/10 Exceptional (187) "Absolute awesome place to stay" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis CA $190 CA $221 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Douglas-House.h110488130.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/98bddc65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabana Cottage](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/75209084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/a5da01ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/cf7f237d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cabana Inn Key West - Adults Only Old Town Key West 8.8/10 Excellent (1011) "A nice place to stay I definitely recommend it." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Vladimir CA $154 CA $237 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-The-Cabana-Inn-Key-West-Adults-Only.h6576609.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/60000/57700/57655/70e7ac88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/60000/57700/57655/3282ab83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/60000/57700/57655/dfaa6255.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe King Room (Not Pet Friendly)](https://images.trvl-media.com/lodging/1000000/60000/57700/57655/eec788b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Palms Hotel Old Town Key West 8.8/10 Excellent (1011) "Great stay, comfortable room and beds, perfect location! " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen CA $248 CA $311 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Key-West-Hotels-The-Palms-Hotel.h57655.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/530000/529500/529427/c8bd1ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/530000/529500/529427/8616a4ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/530000/529500/529427/244a3627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room,w/balcony. 1 King Bed](https://images.trvl-media.com/lodging/1000000/530000/529500/529427/f9abeb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duval Inn Old Town Key West 8.6/10 Excellent (705) "Great location, clean comfortable rooms, great staff" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond CA $191 CA $271 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Duval-Inn.h529427.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10540000/10531800/10531753/ac0b6e27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 1 Bedroom, Kitchen (25) | Terrace/patio](https://images.trvl-media.com/lodging/11000000/10540000/10531800/10531753/0c8ddcdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds (Room 24) | Private kitchen](https://images.trvl-media.com/lodging/11000000/10540000/10531800/10531753/56547671.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10540000/10531800/10531753/724424f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coconut Bay Resort Key Largo Key Largo 9.6/10 Exceptional (189) "beautiful place." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Karl [](https://www.expedia.ca/Key-Largo-Hotels-Coconut-Bay-Resort-Key-Largo.h10531753.Hotel-Information) ![Classic Room, 1 Queen Bed, Balcony, Pool View (1) | Balcony view](https://images.trvl-media.com/lodging/101000000/100750000/100745100/100745070/10660828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room, 1 Queen Bed, Balcony, Pool View](https://images.trvl-media.com/lodging/101000000/100750000/100745100/100745070/3d1c0cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100750000/100745100/100745070/2d2bd17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room, 1 King Bed, Ground Floor](https://images.trvl-media.com/lodging/101000000/100750000/100745100/100745070/987af2ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curry House Old Town Key West 7.2/10 Good (43) "Great property for couples looking to explore keywest! Very clean, great virtual staff communication, close to everything! I was very impressed and will recommend to family and friends. Skip the overinflated hotels, this is all you need, grocery store 3 minute walk away." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $159 CA $487 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-Curry-House.h100745070.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/4d24feec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/8717bede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/769f8ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/b2259b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heron House Court - Adult Only Key West Historic District 9.0/10 Wonderful (1008) "Good location for me.. Stayed here many times" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $234 CA $306 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Key-West-Hotels-Heron-House-Court-Adult-Only.h902014.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/9000000/8660000/8657100/8657021/bc64cbf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Studio, 1 King Bed (Room 2a)](https://images.trvl-media.com/lodging/9000000/8660000/8657100/8657021/974a1d0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/9000000/8660000/8657100/8657021/86679c60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8660000/8657100/8657021/663b0ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Key West Hotel Key West Historic District 9.2/10 Wonderful (500) "My wife and I have come to KeyWest for years, this by far the nicest and affordable with great music and staff. It's our new go to place!" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $309 CA $347 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-Casa-325.h8657021.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2240000/2232000/2231933/a17d99e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2240000/2232000/2231933/b83c4cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2240000/2232000/2231933/e6b2a42c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2240000/2232000/2231933/40114484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coco Plum Inn Old Town Key West 9.6/10 Exceptional (456) "Overall great for couple's stay. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Quazi CA $230 CA $259 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-Coco-Plum-Inn.h2231933.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/55000000/54240000/54232900/54232858/f7ac1cde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54240000/54232900/54232858/98d2114e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54240000/54232900/54232858/be9325ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/55000000/54240000/54232900/54232858/862091af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mermaid & Alligator Old Town Key West 9.8/10 Exceptional (262) "Very Clean,Quiet and Confy" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $326 CA $367 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Key-West-Hotels-The-Mermaid-Alligator.h54232858.Hotel-Information) ![Fountain](https://images.trvl-media.com/lodging/37000000/36260000/36259400/36259375/a3570bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Palm 1 Bedroom Suite | Living area](https://images.trvl-media.com/lodging/37000000/36260000/36259400/36259375/e8fb967e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coconut King](https://images.trvl-media.com/lodging/37000000/36260000/36259400/36259375/11874c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36260000/36259400/36259375/146db7dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Colors on White Old Town Key West 8.0/10 Very good (367) "Very nice place to be at. Close walking and biking distance " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) brad CA $213 CA $240 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Key-West-Hotels-Colors-On-White.h36259375.Hotel-Information) ![Sweet Caroline - Two Bedroom Spacious Apartment | Private kitchen](https://images.trvl-media.com/lodging/111000000/110350000/110348200/110348140/c51ae976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/111000000/110350000/110348200/110348140/ae6676ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banana Split | Private kitchen](https://images.trvl-media.com/lodging/111000000/110350000/110348200/110348140/41a18a0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sweet Caroline - Two Bedroom Spacious Apartment](https://images.trvl-media.com/lodging/111000000/110350000/110348200/110348140/9c58be32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Banana's Foster Guesthouse Key West Historic District 8.8/10 Excellent (6) "The hotel is an old building built in the 1800s and it shows the condition of the rooms were not perfect. It was OK for the few days we needed to stay but for the price the chain hotel might be better." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $198 CA $452 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-Bananas-Foster-Guesthouse.h110348140.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/11000000/10980000/10974500/10974431/f74278e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 1 King Bed with Sofabed, Kitchen at Wicker House, 913 Duval Street | In-room dining](https://images.trvl-media.com/lodging/11000000/10980000/10974500/10974431/5d99f028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room 1 King Bed at Wicker House, 913 Duval Street](https://images.trvl-media.com/lodging/11000000/10980000/10974500/10974431/9860b470.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10980000/10974500/10974431/dc482680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wicker Guesthouse Old Town Key West 8.6/10 Excellent (1000) "This place is a rare gem!! My family loved staying here, it was beautiful!" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Evan CA $326 CA $398 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Key-West-Hotels-Wicker-Guesthouse.h10974431.Hotel-Information) ![King Suite Pool View](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635855/0be5a7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635855/bbb6c4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635855/9a87faac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coconut King | Living area](https://images.trvl-media.com/lodging/2000000/1640000/1635900/1635855/673d8b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kona Kai Oasis Old Town Key West 8.2/10 Very good (566) "The room is very clean and spacious. The location is great!" ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Minna CA $276 CA $311 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Key-West-Hotels-An-Island-Oasis.h1635855.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798025/d48732c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798025/81ab214b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798025/736f38f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/2000000/1800000/1798100/1798025/6b18e30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Grand Guesthouse Old Town Key West 9.6/10 Exceptional (1006) "Excellent place to stay in Key West. " ![](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos Alejandro CA $271 CA $340 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Key-West-Hotels-The-Grand-Guesthouse.h1798025.Hotel-Information) ![Superior Villa, 2 Bedrooms, Private Pool (Room 409) | Outdoor pool](https://images.trvl-media.com/lodging/4000000/3080000/3074000/3073969/2ce64ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/4000000/3080000/3074000/3073969/68f4d301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage - Kitchen | Private kitchen](https://images.trvl-media.com/lodging/4000000/3080000/3074000/3073969/189f0c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage - Kitchen | View from property](https://images.trvl-media.com/lodging/4000000/3080000/3074000/3073969/6fbb2ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans House - Gay Men Adult Resort Old Town Key West 8.6/10 Excellent (336) "Pool bar has very high prices. Otherwise a great place to stay." ![](https://a.travel-assets.com/egds/marks/flags/us.svg) KEN CA $294 CA $346 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Key-West-Hotels-New-Orleans-House-Gay-Men-Adult-Resort.h3073969.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=6023765&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorida-Keys-Guest-Houses.d6023765-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorida-Keys-Guest-Houses.d6023765-aaGuestHouses.Travel-Guide-Accommodation) ## Top Florida Keys Hotel Reviews ![Waterside Suites & Marina](//images.trvl-media.com/lodging/1000000/20000/13800/13719/7b7ca43b_y.jpg) ### Waterside Suites & Marina 10/10 Excellent "This was right next to the departure point for Rainbow Reef's scuba diving boats, making it super easy to do a dive week without driving all over. The kitchen in the room was a nice addition as well." [](https://expedia.ca/Key-Largo-Hotels-Waterside-Suites-Marina.h13719.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "Excellent hotel " [](https://expedia.ca/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Reefhouse Resort & Marina](//images.trvl-media.com/lodging/1000000/10000/3500/3427/af093823_y.jpg) ### Reefhouse Resort & Marina 10/10 Excellent "Very friendly staff. " [](https://expedia.ca/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Chesapeake Beach Resort](//images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg) ### Chesapeake Beach Resort 10/10 Excellent "The pools where very clean and very comfy, the place is keep very clean. Thank you." [](https://expedia.ca/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ![The Pelican Key Largo Cottages](//images.trvl-media.com/lodging/7000000/6840000/6839400/6839376/f35b06df_y.jpg) ### The Pelican Key Largo Cottages 10/10 Excellent "Check in was simple! Cottage is amazing, clean and beds are super comfortable. Bonus is the view and activities available. Even though we were checking out they offered us to still use the kayaks before we left. Definitely would stay here again! " [](https://expedia.ca/Key-Largo-Hotels-The-Pelican-Key-Largo-Cottages.h6839376.Hotel-Information) ![Rock Reef Resort](//images.trvl-media.com/lodging/58000000/57190000/57185500/57185414/6ddda999_y.jpg) ### Rock Reef Resort 10/10 Excellent "It was a perfect stay Beautiful place, very clean and better located. The associates were very nice and helpful " [](https://expedia.ca/Key-Largo-Hotels-Rock-Reef-Resort.h57185414.Hotel-Information) ![Amara Cay Resort](//images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg) ### Amara Cay Resort 10/10 Excellent "It was great weekend! Clean room, nice service" [](https://expedia.ca/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Cheeca Lodge & Spa](//images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "I went there this weekend to celebrate my birthday. Great place, well kept, nice service, rooms are pretty and clean. The pools are nice. Loved the resort. Hope to come back soon. They had a room for me right away. Check in was very pleasant. The paddle boarding, and canoes are free with the stay. I enjoyed my stay so much! Coming back home very relaxed! The only things I didn’t like were: my room didn’t have a shower cap or a shower mat, the fire pits were not on at night. Other than that everything was superb! They sent me a msg to see if everything was great and asked if I needed anything to let them know. I will be coming back! " [](https://expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Hampton Inn Key Largo Manatee Bay](//images.trvl-media.com/lodging/1000000/10000/5800/5731/68e30233_y.jpg) ### Hampton Inn Key Largo Manatee Bay 10/10 Excellent "Enjoyed our stay!!! " [](https://expedia.ca/Key-Largo-Hotels-Hampton-Inn-Key-Largo-Manatee-Bay.h5731.Hotel-Information) ## Find out more about Florida Keys ## Florida Keys Guest Houses information | Number of reviews | | | --- | --- | | Accommodation | Guest Houses | | Lowest Price | | | Highest Price | | ## Frequently asked questions ### What is the nightly rate for a guest house in Florida Keys? > Rates for Florida Keys guest houses vary, but travelers can find great-value prices with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Florida Keys guest houses tend to be higher. Remember to also use our filters to sort prices from low to high. ### What's the difference between a Florida Keys guest house and a B&B? > A guest house in Florida Keys is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house. ## Explore a world of travel with Expedia - Lodging - Packages - More ways to book - [Hotels near Christ of the Abyss](https://www.expedia.ca/Christ-Of-The-Abyss-Hotels.0-l6069273-0.Travel-Guide-Filter-Hotels) - [Hotels near John Pennekamp Coral Reef State Park](https://www.expedia.ca/John-Pennekamp-Coral-Reef-State-Park-Hotels.0-l6068611-0.Travel-Guide-Filter-Hotels) - [John Pennekamp Coral Reef State Park](https://www.expedia.ca/John-Pennekamp-Coral-Reef-State-Park-United-States-of-America.d6068611.Vacation-Attraction) - [Book Guest Houses in Florida Keys on Expedia.com](https://www.expedia.com/Florida-Keys-Guest-Houses.d6023765-aaGuestHouses.Travel-Guide-Accommodation)