Commerce Vacation Rentals

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Browse Select Commerce Vacation Homes

Our top choices for Commerce vacation homes

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

2.0 star property
9.8 out of 10, Exceptional, (18)
"Great place to stay. "
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (140)
"Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay. "
The price is CA $206
CA $337 total
includes taxes & fees
Sep 2 - Sep 3
Serenity South -- Gardens, River-Views, and Refreshing Space

Urban 2-bedroom Escape in Downtown Cape Girardeau

10.0 out of 10, Exceptional, (4)
"Great house in a great location. Well-stocked kitchen with some thoughtful extras. You can tell that the owner cares which means a lot to someone originally from Cape. 10/10 would stay again."
Urban 2-bedroom Escape in Downtown Cape Girardeau

Super cute family friendly 3-bedroom house in Cape Girardeau with AC, WiFi

Super cute family friendly 3-bedroom house in Cape Girardeau with AC, WiFi

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (33)
"all was so nice and we enjoyed our stay. grandkids and us loved having pool table and card games and all the peace and quiet there. thank u again for contacting me and giving us address. we appreciated that very much. "
The price is CA $206
CA $317 total
includes taxes & fees
Oct 1 - Oct 2
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (43)
"I would definitely stay here again!"
The price is CA $111
CA $139 total
includes taxes & fees
Sep 7 - Sep 8
Little Blue Cottage on Spanish

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

10.0 out of 10, Exceptional, (21)
"Lovely home perfect for our weekend celebrating our daughter’s graduation. Chip was an excellent host, even found us champagne flutes! Beds were comfortable, house was clean and nicely decorated. "
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.4 out of 10, Exceptional, (6)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is CA $411
CA $641 total
includes taxes & fees
Oct 1 - Oct 2
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (37)
"Quaint, little property with roomy accommodations. So much better than 4 people sharing a hotel room…everyone had their own space. The location was convenient, quiet and the neighborhood felt safe."
Quaint, Beautiful Home next to SEMO and Hospital

Next Door to Mercy Hospital - Pet Friendly - Fast Wifi

8.0 out of 10, Very good, (5)
"Great place for our family to have a quick get together in short notice."
The price is CA $311
CA $652 total
includes taxes & fees
Sep 6 - Sep 7
Next Door to Mercy Hospital - Pet Friendly - Fast Wifi

Charming 3-bedroom house near downtown

2.0 star property
10.0 out of 10, Exceptional, (2)
"My husband and I along with one other couple stayed here while in Cape for a wedding. The location was nice and was a short distance for driving or Ubering around town. The price was great!! Highly recommend."
Charming 3-bedroom house near downtown

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (7)
"We thoroughly enjoyed the property. Very unique and fun. "
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Steps to Southeast Hospital - Fast Wifi - King Bed

10.0 out of 10, Exceptional, (6)
"This was the perfect place for us to have a small group weekend getaway! All the beds were comfy! High quality sheets! Very clean! "
Steps to Southeast Hospital - Fast Wifi - King Bed

Country Setting & Views - Garage Parking - Fast Wifi

8.0 out of 10, Very good, (1)
"Very nice property in a very nice location. Overall a nice place to stay. Pros: 1) House by itself on a large piece of land 2) Very quiet and peaceful 3)House is large with plenty of room 4) Nicely remodeled with very nice furnishings 5) The one bed we slept on was very comfortable 6) Amazing view of the sun coming up over the hill in the mornings Cons: 1) Although newly remodeled, it's still a very old house and the old house smell is crazy strong. I mean VERY strong 2) The smart thermostat...
Country Setting & Views - Garage Parking - Fast Wifi

Historic 2-Story Foursquare Home - C.1847 - River Views - Fast Wifi

9.6 out of 10, Exceptional, (15)
"Wonderful older house with great updates! Beds were comfortable and the yard lovely. "
Historic 2-Story Foursquare Home - C.1847 - River Views - Fast Wifi

Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi

10.0 out of 10, Exceptional, (4)
"The property was nice, spacious, and easy access to everything! We enjoyed our stay!"
Large Home next to Southeast Hospital - 2 King Beds - Fast Wifi

Building at Cape Girardeau Regional Airport

The price is CA $687
CA $840 total
includes taxes & fees
Sep 2 - Sep 3
Building at Cape Girardeau Regional Airport

The cabin in Eden

9.6 out of 10, Exceptional, (18)
"I stayed here with my teenage daughter and newborn son during the 2024 eclipse. It was very comfortable for us amd very clean. The property is in an excellent location. It is close to many antique stores and great eats! The river is close and we had the pleasure of visiting the Old St. Vincent's (across the street) for Divine Mercy Sunday with the prayers, adoration, and confession. It was lovely! Matt (the host) was clear on directions and we didn't have any trouble contacting him. Even though...
The cabin in Eden

SEMO Redhawks Campus Home with Hot Tub

SEMO Redhawks Campus Home with Hot Tub

Cheerful 3-Bedroom Home

Cheerful 3-Bedroom Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Commerce Hotel Reviews

Find out more about Commerce

Find out more about Commerce

Commerce Vacation Homes information

Number of reviews
Accommodation
14 Vacation Homes
Lowest Price
CA $111
Highest Price
CA $687

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