Title: Commerce Vacation Home Rentals from CA $141: Search Top Private Vacation Homes for Rent | Expedia.ca [Hotels in Commerce](https://expedia.ca/Commerce-Hotels.d553248634983177483.Travel-Guide-Hotels)[Vacation Rentals in Commerce](https://expedia.ca/Commerce-Vacation-Rentals.d553248634983177483.Travel-Guide-VacationRentals)[Commerce Car Rentals](https://expedia.ca/Car-Rentals-In-Commerce.d553248634983177483.Car-Rental-Guide)[Commerce Vacation Packages](https://expedia.ca/Commerce.d553248634983177483.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Commerce Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248634983177483&startDate=2025-11-07&endDate=2025-11-09&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248634983177483&startDate=2025-11-14&endDate=2025-11-16&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248634983177483&startDate=2025-11-28&endDate=2025-11-30&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248634983177483&startDate=2025-12-26&endDate=2025-12-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Commerce Vacation Homes ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/a97a55c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/w2034h1144x0y4-942ecedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/b5e1a6cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/4aa961ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool Cape Girardeau 8.8/10 Excellent (34) "Abbie was an amazing hostess. She was great with communicating with our group and made our stay awesome. She was very accommodating and made sure we had everything we needed to make our trip perfect. The house and pool were great. We were very pleased. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie H. CA $188 CA $302 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/ad11073b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish Cape Girardeau 8.6/10 Excellent (45) "Some issues with check-in. Very nice area. Lot of history." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey M. CA $113 CA $141 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6b76cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serenity South -- Gardens, River-Views, and Refreshing Space Cape Girardeau 10/10 Exceptional (144) "Enjoyed everything! Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jodie F. CA $209 CA $342 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/2cc8556c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/07e510a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/67038c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111971500/111971489/d2b33581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More Cape Girardeau 9.6/10 Exceptional (7) "Nice place, great times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jace W. CA $375 CA $610 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cape-Girardeau-Hotels-4-Bedroom-Home-2-King-Beds.h111971489.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/1c6c31ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/450d2061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/7dffb73b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/d39634e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Building at Cape Girardeau Regional Airport Scott City CA $697 CA $852 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=553248634983177483&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCommerce-Private-Vacation-Homes.d553248634983177483-aaPrivateVacationHomes.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCommerce-Private-Vacation-Homes.d553248634983177483-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Commerce Hotel Reviews ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "It was a nice stay" [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Enjoyed the evening meal. Children enjoyed the hotdogs and nachos. Everything was great!" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](//images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Appears to be a newer property in very nice, new condition." [](https://expedia.ca/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Amazing…just finished a 90 mile bike ride into the wind and was looking forward to a little nicer hotel with a hot tub. Awesome room, free drinks, free dinner, great breakfast…and the hot tub. Employees were awesome too. No Drury inns where I live but I will always look for them when I travel" [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The beds were so comfortable!" [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great stay" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Super 8 by Wyndham Charleston/Sikeston East MO](//images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39_y.jpg) ### Super 8 by Wyndham Charleston/Sikeston East MO 10/10 Excellent "Thank you " [](https://expedia.ca/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Very nice stay." [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Nice and quiet, beautiful and historic!" [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ## Find out more about Commerce ## Commerce Vacation Homes information | Number of reviews | 230 | | --- | --- | | Accommodation | 24 Vacation Homes | | Lowest Price | CA $141 | | Highest Price | CA $852 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [B&B in Advance](https://www.expedia.ca/Advance-Bed-And-Breakfast.d553248634983475122-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Advance](https://www.expedia.ca/Advance-Lodges.d553248634983475122-aaLodges.Travel-Guide-Accommodation) - [Motels in Advance](https://www.expedia.ca/Advance-Motels.d553248634983475122-aaMotels.Travel-Guide-Accommodation) - [Apartments in Baker](https://www.expedia.ca/Baker-Apartments.d553248634983252914-aaApartments.Travel-Guide-Accommodation) - [Apartments in Bell City](https://www.expedia.ca/Bell-City-Apartments.d553248634983588961-aaApartments.Travel-Guide-Accommodation) - 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