Find Spa Hotels in Charleston, MO from CA $162

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Check availability on Charleston Spa Hotels

Tonight
May 8 - May 9
Tomorrow
May 9 - May 10
This weekend
May 8 - May 10
Next weekend
May 15 - May 17

Our top choices for Charleston hotels with a spa

Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
  • cleanliness
    Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
"Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious. "
United States
Laura
The price is CA $143
CA $162 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Charleston

Pool
Breakfast included

Top Charleston Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Nice place. Meal ok. "
Mary 1-night trip
Posted 2 days ago
Drury Inn & Suites Cape Girardeau

Frequently asked questions

Looking for a spa hotel in Charleston?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the opera and restaurants in Charleston—your day trip starts here. Be sure to pay a visit to the churches during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Charleston?
Experience all that Charleston has to offer when you visit Mississippi River, Ohio River, and Fort Defiance State Park. If you have a bit of extra time while you're in the area, you might want to check out Sikeston Depot Museum and Columbus-Belmont State Park.
What is a Charleston spa hotel?
Spa hotels in Charleston provide lodging and have an on-site spa offering services like facials and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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