[See all properties](http://www.expedia.ca/Hotel-Search?regionId=&adults=2&children=&sort=RECOMMENDED&useRewards=false&semdtl=&userIntent=&vip=false) Entire home # Serenity South -- Gardens, River-Views, and Refreshing Space Riverfront vacation home with kitchen and balcony ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/29617056.jpg?impolicy=resizecrop&rw=598&ra=fit) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/ec557893.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Interior](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/a340bc3f.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/c59bcf0b.jpg?impolicy=resizecrop&rw=297&ra=fit) ![Outdoor dining](https://images.trvl-media.com/lodging/39000000/38950000/38940200/38940154/6b76cbc5.jpg?impolicy=resizecrop&rw=297&ra=fit) - Overview - Amenities - Policies - Location In the heart of Cape Girardeau Historic District, this beautifully renovated duplex offers a cozy living room and large dining room perfect for relaxation. Explore downtown's local restaurants, antique shops, and boutiques within walking distance or unwind on the balcony overlooking the shared yard. 10 Exceptional ### Entire home 3 bedrooms2 bathroomsSleeps 51600 sq ft ## Popular amenities - - Kitchen - Parking available - Fireplace - Outdoor space ## Add dates for prices Check-in Check-out Travellers ## About this property ### Entire place You'll have the entire home to yourself and will only share it with other guests in your party. ### Serenity South -- Gardens, River-Views, and Refreshing Space Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions. ## Property amenities ### Internet - Available in the house: WiFi ### Parking and transportation - Car not required - Parking on site ### Kitchen - Coffee grinder - Coffee/tea maker - Cookware, dishware, and utensils - Dishwasher - Ice maker - Microwave - Oven - Paper towels - Refrigerator - Spices - Stovetop - Toaster ### Bedrooms - 3 bedrooms - Bedsheets provided ### Bathroom - 1.5 bathrooms - Bathtub or shower - Hair dryer - Shampoo - Soap - Toilet paper - Towels provided ### Living spaces - Fireplace - Living room - Separate dining area ### Entertainment - Books - DVD player - Games - TV ### Outdoor areas - Balcony - Garden - Outdoor furniture ### Laundry - Laundromat nearby ### Comfort - Air conditioning - Heating ### Pets - No pets allowed ### Suitability/Accessibility - Smoking not allowed ### Services and conveniences - Iron/ironing board ### Location highlights - Near a health/beauty spa - Near a hospital - Near an outlet shopping mall - On a river ### Things to do - Water park - Basketball nearby - Casino nearby - Cycling nearby - Fishing nearby - Golfing nearby - Hiking/biking trails nearby - Horseback riding nearby - Motor boating nearby - Swimming nearby - Wildlife walks nearby - Winery tours nearby ### Safety features - Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property) - Smoke detector (host has indicated there is a smoke detector on the property) - Deadbolt lock ### General - Garden - Unit size: 1,600 square feet ## Similar properties ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71740000/71736900/71736900/17fd79b9.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO Cape Girardeau - Kitchen - Free WiFi - Air conditioning - Outdoor space 9.6 Exceptional 40 reviews CA $114 CA $193 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20&selected=71736900&PinnedHotelID=71736900&HadPinnedHotel=true®ionId=-1&adults=2) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76550000/76544100/76544096/b002a425.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau Cape Girardeau - Kitchen - Washer - Dryer - Free WiFi 10 Exceptional 22 reviews [](https://www.expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23&selected=76544096&PinnedHotelID=76544096&HadPinnedHotel=true®ionId=-1&adults=2) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/066095c4.jpg?impolicy=fcrop&w=469&h=201&p=1&q=medium) ### Loft Apartment Across From Semo University Houch Field House. 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Please respect their use of the common space. ### Pets Pets not allowed ### Children and extra beds Children are welcome Note from host: Excellent fenced back yard. ### Events Events allowed: family gatherings, birthday parties, weddings Parties or events must okayed before arrival. ### Smoking Smoking is not permitted ## Important information ### You need to know Extra-person charges may apply and vary depending on property policy Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed Parties and events (including family gatherings, birthday parties and weddings) are allowed on site; maximum attendees: 50 Note from host: Parties or events must okayed before arrival. Host has indicated there is a carbon monoxide detector on the property Host has indicated there is a smoke detector on the property Safety features at this property include a deadbolt lock This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation ### We should mention A car is not required for transportation to and from this property ## About the area Located in Cape Girardeau, this vacation home is on a river. The area's natural beauty can be seen at Shawnee National Forest and Mississippi River. Traveling with kids? Consider Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. Discover the area's water adventures with motor boating and fishing nearby, or enjoy the great outdoors with cycling and hiking/biking trails. [Visit our Cape Girardeau travel guide](https://www.expedia.ca/Cape-Girardeau.dx820) [View more Vacation homes in Cape Girardeau](https://www.expedia.ca/Cape-Girardeau-Private-Vacation-Homes.d820-aaPrivateVacationHomes.Travel-Guide-Accommodation) ![Map](https://maps.googleapis.com/maps/api/staticmap?&size=660x330&map_id=3b266eb50d2997c6&zoom=13&markers=icon:https%3A%2F%2Fa.travel-assets.com%2Ftravel-assets-manager%2Feg-maps%2Fproperty.png%7C37.30075%2C-89.51995&channel=expedia-HotelInformation&maptype=roadmap&scale=1&key=AIzaSyCYjQus5kCufOpSj932jFoR_AJiL9yiwOw&signature=dshoScVVRLX4BbV52kd9Dl-8cK8=) Cape Girardeau, MO ### What's nearby - Riverfront Park - 2 min walk - 0.2 km - Riverfront Bridge Park - 6 min walk - 0.6 km - Isle Casino Cape Girardeau - 16 min walk - 1.4 km - Southeast Missouri State University - 2 min drive - 1.8 km - Show Me Center - 3 min drive - 2.8 km ### Getting around - Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 12 min drive ### Restaurants - ‪Sand's Pancake House - ‬11 min walk - ‪Katy O'Ferrell's Publick House - ‬9 min walk - ‪Hotshots Sports Bar & Grill - ‬5 min walk - ‪Minglewood Brewery - ‬7 min walk - ‪Broussard's Cajun Cuisine - ‬7 min walk ## Frequently asked questions ### Is Serenity South -- Gardens, River-Views, and Refreshing Space pet-friendly? > No, pets are not allowed at this property. ### How much does it cost to stay at Serenity South -- Gardens, River-Views, and Refreshing Space? > As of Oct 8, 2025, prices found for a 1-night stay for 2 adults at Serenity South -- Gardens, River-Views, and Refreshing Space on Oct 9, 2025 start from CA $209.16, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. [Choose your dates](https://www.expedia.ca/Sikeston-Hotels-Serenity-Gardens.h38940154.Hotel-Information?rfrr=HOT.HIS.question.link.click) for more accurate prices. ### What time is check-in at Serenity South -- Gardens, River-Views, and Refreshing Space? > Check-in begins at 4:00 PM. ### What time is check-out at Serenity South -- Gardens, River-Views, and Refreshing Space? > Check-out is at 11:00 AM. ### Where is Serenity South -- Gardens, River-Views, and Refreshing Space located? > This family-friendly Cape Girardeau vacation home is located on a river, steps from eDen Spa & Salon, Shawnee National Forest, and Mississippi River. Riverfront Park and Riverfront Bridge Park are also within 5 minutes. ## Have a question? Beta Get instant answers with AI powered search of property information and reviews. 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