5 Stars Hotels in Panama City, Panamá Province from CA $180

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Our top choices for Panama City 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

1. Hotel Riu Plaza Panama

Bella Vista

Ashford J.

CA $205 total

includes taxes & fees

Dec 3 - Dec 4

A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.

2. Waldorf Astoria Panama

Bella Vista

Oscar

CA $461 total

includes taxes & fees

Dec 9 - Dec 10

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

3. Hyatt Regency Panama City

Bella Vista

Mariah

CA $375 total

includes taxes & fees

Dec 12 - Dec 13

A poolside area with lounge chairs and a view of the ocean.

4. JW Marriott Panama

San Francisco

Luz Elizabeth

CA $498 total

includes taxes & fees

Nov 27 - Nov 28

A balcony with a table, chairs, and a view of a city skyline across a body of water.

5. Sofitel Legend Casco Viejo, Panama City

Casco Viejo

Jose

CA $688 total

includes taxes & fees

Nov 18 - Nov 19

A hotel entrance with a central water feature, seating areas, and potted plants.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

Denis

CA $490 total

includes taxes & fees

Nov 27 - Nov 28

A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.

7. W Panama

Bella Vista

Lashann

CA $390 total

includes taxes & fees

Dec 8 - Dec 9

A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

8. Renaissance Panama City Hotel

Bella Vista

Carlos

CA $198 total

includes taxes & fees

Nov 23 - Nov 24

A restaurant with multiple dining tables, chairs, and a central water feature.

9. Hotel La Compañía Casco Antiguo

Casco Viejo

Graham

CA $508 total

includes taxes & fees

Dec 2 - Dec 3

A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

10. Bristol Panama, a Registry Collection Hotel

Bella Vista

Juliet

CA $387 total

includes taxes & fees

Nov 13 - Nov 14

A modern hotel pool area with lounge chairs and a clear view of the ocean.

11. Hilton Panama

Bella Vista

ARIELA

CA $299 total

includes taxes & fees

Nov 13 - Nov 14

A hotel with a pool, beach, and palm trees.

12. The Westin Playa Bonita Panama

Veracruz

Phillip James

CA $334 total

includes taxes & fees

Nov 20 - Nov 21

13. Waymore Hotel Spa and Casino

Bella Vista

Mathe

CA $149 total

includes taxes & fees

Nov 13 - Nov 14

14. Megapolis Hotel Panamá

San Francisco

MARVIN

CA $385 total

includes taxes & fees

Dec 3 - Dec 4

Top Panama City Hotel Reviews

Sofitel Legend Casco Viejo, Panama City

Casco Viejo

10/10 Excellent

My stay at Sofitel Legend in Casco Antiguo was exceptional. The property is beautiful, the historic location adds so much to the experience, and the standard of service matches what you expect from a five-star hotel. What made the stay memorable, however, was the staff. Everyone was welcoming and attentive, with a genuine sense of hospitality. A special mention to Roberto, who was outstanding. He was personable, thoughtful and always seemed to know when assistance was needed without being...

Helen

Hotel La Compañía Casco Antiguo

Casco Viejo

10/10 Excellent

Darija

Hyatt Regency Panama City

Bella Vista

10/10 Excellent

Greg

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

10/10 Excellent

Afua

Hilton Panama

Bella Vista

10/10 Excellent

Very impressive view on the 18th floor with 3 sides floor to ceiling windows. This is the most beautiful view I ever had in a hotel. Room is very comfortable with easy to control room temperature. The shower is very big, good water pressure and hot water. It just leaked a bit on the seam at the bottom. The hotel area is safe but not really safe to walk. On weekdays it's very busy with tons of traffic and very dangerous to cross streets. There are very few cross walks around the building. ...

Ngar

Waldorf Astoria Panama

Bella Vista

10/10 Excellent

Beautiful hotel, very comfortable room especially the beds! Pool was lovely with warm water, gym was very clean and everything was in good working order. Breakfast was really great with an extensive buffet with something for everyone. The best part of the hotel- and this is what separates them from other hotels- is the staff. In every area- from the doormen to the front desk to the concierge to the waiters- each one of them is excellent at their jobs, they always have a smile, and are so...

MMacKinnon

Renaissance Panama City Hotel

Bella Vista

10/10 Excellent

James

The Westin Playa Bonita Panama

Veracruz

10/10 Excellent

Jonah

Find out more about Panama City

Five Star Hotels in Panama City

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Panama City so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Panama City and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Panama City

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Panama City

The results are in, and Panama City 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Panama City! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Panama City today and settle down in the lap of luxury tomorrow.

Frequently Asked Questions

What are the best 5-star hotels in Panama City?

Based on Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Hotel Riu Plaza Panama are among the most popular 5-star hotels in Panama City. Featuring top-quality amenities and excellent service, you'll enjoy a luxurious and memorable stay.

How much does it cost to stay in a 5-star hotel in Panama City?

How much you pay for a 5-star hotel in Panama City depends on factors like when you plan to travel and the length of your break. A top tip for bagging the best deal? Use our pricing filters to check out all of the available options for your preferred dates.

Search for the lowest price per night from CA $180

What makes a hotel 5 stars in Panama City?

From gourmet dining venues and 24-hour gyms to swimming pools and premium bedding, the 5-star experience in Panama City is all about comfort and luxury. But it requires more than just top-notch conveniences to receive a 5-star rating. Stays must also deliver exceptional guest-focused services like in-room massages, on-site dry cleaning and laundry and a nightly turn-down service.

Are there any 5-star all-inclusive resorts in Panama City?

Use our convenient filters to find an upscale escape in Panama City where most of what you need is included in the price. From there, narrow down your results for properties that have a 5-star rating and are described as "All inclusive." The main thing on the schedule at these stays? Relaxation and indulgence.

What are the top 5-star spa hotels in Panama City?

Recharge your batteries with luxurious massages and other revitalizing treatments at Waldorf Astoria Panama. It's one of Panama City's top 5-star spa properties. W Panama and Bristol Panama, a Registry Collection Hotel also combine upmarket accommodations with a range of wellness therapies.

Are there any 5-star vacation rentals in Panama City?

There are no 5-star vacation rentals in Panama City on our site, but there are a range of other highly rated properties worth looking into. Search through our vacation rentals in Panama City to book the ideal place for your getaway.

Are there any 5-star hotels in downtown Panama City?

Check in to Bristol Panama, a Registry Collection Hotel and take advantage of being near the sights and sounds of downtown Panama City.

What are the top 5-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?

Whether you're coming in late or flying out early from Panama City, it's worth looking at Villa Palma Boutique Hotel. This 5-star stay is conveniently located around 3 kilometres southeast of Marcos A. Gelabert Intl. Airport (PAC).

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Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panama City 5-star hotels

1. Hotel Riu Plaza Panama

2. Waldorf Astoria Panama

3. Hyatt Regency Panama City

4. JW Marriott Panama

5. Sofitel Legend Casco Viejo, Panama City

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

7. W Panama

8. Renaissance Panama City Hotel

9. Hotel La Compañía Casco Antiguo

10. Bristol Panama, a Registry Collection Hotel

11. Hilton Panama

12. The Westin Playa Bonita Panama

13. Waymore Hotel Spa and Casino

14. Megapolis Hotel Panamá

Top Panama City Hotel Reviews

Sofitel Legend Casco Viejo, Panama City

10/10 Excellent

Find out more about Panama City

Five Star Hotels in Panama City

Get a Great Deal on 5-Star Hotels in Panama City

Make Your Escape to Panama City

Frequently Asked Questions

What are the best 5-star hotels in Panama City?

How much does it cost to stay in a 5-star hotel in Panama City?

What makes a hotel 5 stars in Panama City?

Are there any 5-star all-inclusive resorts in Panama City?

What are the top 5-star spa hotels in Panama City?

Are there any 5-star vacation rentals in Panama City?

Are there any 5-star hotels in downtown Panama City?

What are the top 5-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?

Explore a world of travel with Expedia