Title: 5 Stars Hotels in Historic Route 66, United States of America from CA $159 - Find Cheap Historic Route 66 Hotels With 5 Stars | Expedia.ca

[Historic Route 66 Travel Guide](https://expedia.ca/Historic-Route-66.dx702654640613646336)[Hotels in Historic Route 66](https://expedia.ca/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Vacation Rentals in Historic Route 66](https://expedia.ca/Historic-Route-66-Vacation-Rentals.d702654640613646336.Travel-Guide-VacationRentals)[Flights to Historic Route 66](https://expedia.ca/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Car Rentals](https://expedia.ca/Car-Rentals-In-Historic-Route-66.d702654640613646336.Car-Rental-Guide)[Historic Route 66 Vacation Packages](https://expedia.ca/Historic-Route-66.d702654640613646336.Destination-Travel-Guides)

![North Central Arizona showing signage](https://images.trvl-media.com/place/1218/93b64b3e-64f1-4166-b6ae-c4c686f3ea8b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# 5 Stars Hotels in Historic Route 66, United States of America from CA $159

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check availability on Historic Route 66 5 Star Hotels

Tonight

[Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=702654640613646336&startDate=2025-12-18&endDate=2025-12-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=702654640613646336&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=702654640613646336&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=702654640613646336&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Historic Route 66 5-star hotels

![Reception](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/7da48e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/ee956af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/56d62feb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/fc796025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel Chicago

[](https://www.expedia.ca/Chicago-Hotels-Four-Seasons-Hotel-Chicago.h25748.Hotel-Information)

Downtown Chicago

9.4/10

Exceptional

(1003)

"Amazing place! Our family of 6 had a fantastic time here for a night. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brooke

CA $579

CA $680 total

includes taxes & fees

Jan 11 - Jan 12, 2026

[](https://www.expedia.ca/Chicago-Hotels-Four-Seasons-Hotel-Chicago.h25748.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/7000000/6310000/6309400/6309326/33b4ff92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Club Suite, 1 Bedroom, Lake View](https://images.trvl-media.com/lodging/7000000/6310000/6309400/6309326/9a653c17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner served, Mediterranean cuisine](https://images.trvl-media.com/lodging/7000000/6310000/6309400/6309326/71f6a2f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/7000000/6310000/6309400/6309326/0c7c3240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Langham, Chicago

[](https://www.expedia.ca/Chicago-Hotels-The-Langham.h6309326.Hotel-Information)

Downtown Chicago

9.8/10

Exceptional

(1003)

"Langham is always a superior stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

THADDEUS LAMONT

CA $558

CA $655 total

includes taxes & fees

Jan 11 - Jan 12, 2026

[](https://www.expedia.ca/Chicago-Hotels-The-Langham.h6309326.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/590000/581300/581213/f1144862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ballroom](https://images.trvl-media.com/lodging/1000000/590000/581300/581213/5616df34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/590000/581300/581213/acbf2aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/1000000/590000/581300/581213/6ca152e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Peninsula Chicago

[](https://www.expedia.ca/Chicago-Hotels-The-Peninsula-Chicago.h581213.Hotel-Information)

Downtown Chicago

9.8/10

Exceptional

(1008)

"Rooms were cozy and comfortable!!!! The staff was very welcoming, we visited in the month of December the Christmas decor was 100% amazing "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

christie

CA $607

CA $713 total

includes taxes & fees

Jan 16 - Jan 17, 2026

[](https://www.expedia.ca/Chicago-Hotels-The-Peninsula-Chicago.h581213.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723215/209f8cff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Body treatments, body wraps, body scrubs, facials](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723215/743bf216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723215/4465cc02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723215/c35e7743.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Trump International Hotel & Tower Chicago

[](https://www.expedia.ca/Chicago-Hotels-Trump-International-Hotel-Tower-Chicago.h1723215.Hotel-Information)

Downtown Chicago

9.4/10

Exceptional

(1784)

"Amazing hotel, location, staff, and food!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wendy

CA $409

CA $480 total

includes taxes & fees

Jan 18 - Jan 19, 2026

[](https://www.expedia.ca/Chicago-Hotels-Trump-International-Hotel-Tower-Chicago.h1723215.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2720000/2717600/2717582/1040fa3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/3000000/2720000/2717600/2717582/9baa79de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2720000/2717600/2717582/5001f31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/3000000/2720000/2717600/2717582/c47ab94b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waldorf Astoria Chicago

[](https://www.expedia.ca/Chicago-Hotels-Waldorf-Astoria-Chicago.h2717582.Hotel-Information)

Downtown Chicago

9.4/10

Exceptional

(1002)

"Absolutely fantastic hotel great service, you couldn’t ask for more."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

J Michael

CA $523

CA $614 total

includes taxes & fees

Jan 18 - Jan 19, 2026

[](https://www.expedia.ca/Chicago-Hotels-Waldorf-Astoria-Chicago.h2717582.Hotel-Information)

![Suite, Terrace (Water Tower)](https://images.trvl-media.com/lodging/1000000/30000/20700/20695/c7c718ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20700/20695/ca3d604d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (LAKE MICHIGAN SUITE) | View from room](https://images.trvl-media.com/lodging/1000000/30000/20700/20695/ef2f5d42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20700/20695/3c600fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Park Hyatt Chicago

[](https://www.expedia.ca/Chicago-Hotels-Park-Hyatt-Chicago.h20695.Hotel-Information)

Downtown Chicago

9.6/10

Exceptional

(1000)

"Stay was amazing!!! The staff was so friendly, kind, and thoughtful! The rooms were soooo beyond perfect and lovely! And the food at the restaurant was amazing.. especially breakfast! You won’t regret staying here!!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Larissa

CA $509

CA $597 total

includes taxes & fees

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/Chicago-Hotels-Park-Hyatt-Chicago.h20695.Hotel-Information)

![Indoor pool, open 6:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/37000000/36480000/36475600/36475533/486e1134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/37000000/36480000/36475600/36475533/82915bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36480000/36475600/36475533/37b7786f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/37000000/36480000/36475600/36475533/8f021abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nobu Hotel Chicago

[](https://www.expedia.ca/Chicago-Hotels-Nobu-Hotel-Chicago.h36475533.Hotel-Information)

Downtown Chicago

9.4/10

Exceptional

(760)

"Great location, amenities and staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nicholas

CA $361

CA $424 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Chicago-Hotels-Nobu-Hotel-Chicago.h36475533.Hotel-Information)

![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/641d7f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment rooms, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/5b370fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel St Louis

[](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information)

Downtown St. Louis

9.4/10

Exceptional

(1002)

"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lynne

CA $571

CA $668 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/14500/14447/30b68b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/1000000/20000/14500/14447/75bfc3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/20000/14500/14447/bedaec25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14500/14447/4690ab59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ritz-Carlton, Chicago

[](https://www.expedia.ca/Chicago-Hotels-The-Ritz-Carlton.h14447.Hotel-Information)

Downtown Chicago

9.2/10

Wonderful

(1001)

"Festive, staff, food and bar all a perfect 10!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela

CA $510

CA $598 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Chicago-Hotels-The-Ritz-Carlton.h14447.Hotel-Information)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/92000000/91140000/91139000/91138950/0d225744.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Banquet hall](https://images.trvl-media.com/lodging/92000000/91140000/91139000/91138950/bd0f84f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/92000000/91140000/91139000/91138950/w4000h2645x0y22-fdcb2993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/92000000/91140000/91139000/91138950/43b7d4aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The St. Regis Chicago

[](https://www.expedia.ca/Chicago-Hotels-The-St-Regis-Chicago.h91138950.Hotel-Information)

Downtown Chicago

9.2/10

Wonderful

(85)

"Nice place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $614

CA $720 total

includes taxes & fees

Jan 2 - Jan 3, 2026

[](https://www.expedia.ca/Chicago-Hotels-The-St-Regis-Chicago.h91138950.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/9a597e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/dbe99670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/w4000h2663x0y0-dfd3faff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ritz-Carlton, St. Louis

[](https://www.expedia.ca/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information)

Clayton

9.2/10

Wonderful

(553)

"Service is exceptional!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jorge

CA $686

CA $801 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2200/2125/f0a7407b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/2200/2125/fd2c83d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/10000/2200/2125/067ceb17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Studio Suite, Balcony](https://images.trvl-media.com/lodging/1000000/10000/2200/2125/acdcbbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rosewood Inn of the Anasazi

[](https://www.expedia.ca/Santa-Fe-Hotels-Rosewood-Inn-Of-The-Anasazi.h2125.Hotel-Information)

Downtown Santa Fe

9.4/10

Exceptional

(862)

"Wonderful staff and very clean accommodations "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Virginia

CA $660

CA $835 total

includes taxes & fees

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/Santa-Fe-Hotels-Rosewood-Inn-Of-The-Anasazi.h2125.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Bunkhouse)](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/807aba16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/93204597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/4b0bf4d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bishop's Lodge, Auberge Collection

[](https://www.expedia.ca/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information)

Tesuque

9.4/10

Exceptional

(89)

"Great location, Resort, amenities, excellent service and great restaurant chef!!!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James R

[](https://www.expedia.ca/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11610/b07a93ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/11700/11610/caeb6114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/11700/11610/38b9cae0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/11700/11610/c297766f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Posada de Santa Fe, A Tribute Portfolio Resort & Spa by Marriott

[](https://www.expedia.ca/Santa-Fe-Hotels-La-Posada-De-Santa-Fe.h11610.Hotel-Information)

Historic Eastside

8.2/10

Very good

(1003)

"The staff was super friendly and helpful and we really enjoyed the fireplace in the cold evenings!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey Keith

CA $209

CA $296 total

includes taxes & fees

Jan 6 - Jan 7, 2026

[](https://www.expedia.ca/Santa-Fe-Hotels-La-Posada-De-Santa-Fe.h11610.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/7f6e9855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/06dccf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/753685a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Resort Rancho Encantado Santa Fe

[](https://www.expedia.ca/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information)

Santa Fe

9.4/10

Exceptional

(265)

"Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ILAN

CA $702

CA $873 total

includes taxes & fees

Jan 18 - Jan 19, 2026

[](https://www.expedia.ca/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information)

![Deep-tissue massages, Swedish massages, massages](https://images.trvl-media.com/lodging/36000000/35210000/35209200/35209175/d0c59f0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite (Junior)](https://images.trvl-media.com/lodging/36000000/35210000/35209200/35209175/f64c054b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa, 3 Bedrooms (Luminaria) | Terrace/patio](https://images.trvl-media.com/lodging/36000000/35210000/35209200/35209175/c76355cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa (Luminaria) | Private kitchen](https://images.trvl-media.com/lodging/36000000/35210000/35209200/35209175/598e1564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Inn of The Five Graces

[](https://www.expedia.ca/Santa-Fe-Hotels-The-Inn-Of-The-Five-Graces.h35209175.Hotel-Information)

Downtown Santa Fe

10/10

Exceptional

(11)

"My favorite place to stay in Santa Fe. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jenn

CA $1,445

CA $1,665 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Santa-Fe-Hotels-The-Inn-Of-The-Five-Graces.h35209175.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/116000000/115170000/115163800/115163763/00656023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/116000000/115170000/115163800/115163763/c0bd1b1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115170000/115163800/115163763/6cef91d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115170000/115163800/115163763/5d5af9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Art Villa 

[](https://www.expedia.ca/Chicago-Hotels-Art-Villa.h115163763.Hotel-Information)

West Town

10/10

Exceptional

(2)

[](https://www.expedia.ca/Chicago-Hotels-Art-Villa.h115163763.Hotel-Information)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Historic-Route-66-Hotels.s50-0-d702654640613646336.Travel-Guide-Filter-Hotels)[

Sign up, it's free

](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Historic-Route-66-Hotels.s50-0-d702654640613646336.Travel-Guide-Filter-Hotels)

## Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Historic Route 66.

![Embassy Suites by Hilton Chicago Downtown River North](https://images.trvl-media.com/lodging/1000000/20000/11600/11580/w3840h2859x0y0-5fc518eb_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Embassy Suites by Hilton Chicago Downtown River North

600 N State St Chicago IL

CA $135

CA $159 total

Jan 7 - Jan 8, 2026

includes taxes & fees

8.4/10 Very Good! (5,408 reviews)

[](https://expedia.ca/Chicago-Hotels-Embassy-Suites-Chicago-Downtown.h11580.Hotel-Information)

![Palmer House a Hilton Hotel](https://images.trvl-media.com/lodging/1000000/10000/8100/8079/7f542141_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Palmer House a Hilton Hotel

17 E Monroe St Chicago IL

CA $158

CA $220 total

Dec 28 - Dec 29

includes taxes & fees

8.4/10 Very Good! (2,134 reviews)

[](https://expedia.ca/Chicago-Hotels-Palmer-House-A-Hilton-Hotel.h8079.Hotel-Information)

![Hilton Chicago O'Hare Airport](https://images.trvl-media.com/lodging/1000000/10000/8100/8058/ce2102d4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hilton Chicago O'Hare Airport

O'Hare International Airport Chicago IL

CA $270

CA $316 total

Jan 16 - Jan 17, 2026

includes taxes & fees

8.2/10 Very Good! (2,183 reviews)

[](https://expedia.ca/Chicago-Hotels-Hilton-Chicago-OHare-Airport.h8058.Hotel-Information)

Still don't see what you're looking for?

[See all properties in Historic Route 66.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50)

You can also use these popular filters to refine your search.

[Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=19%2F12%2F2025&endDate=20%2F12%2F2025&regionId=702654640613646336&star=50&star=50&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Learn more about Historic Route 66

Check out the local area in Historic Route 66—home to attractions like National Route 66 Museum and Skelly Field at H.A. Chapman Stadium.

[See all hotels in Historic Route 66](https://www.expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02&adults=2&regionId=702654640613646336)

![North Central Arizona showing signage](https://images.trvl-media.com/place/1218/93b64b3e-64f1-4166-b6ae-c4c686f3ea8b.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Historic Route 66 Hotel Reviews

## Find out more about Historic Route 66

Luxury is the name of the game at the best 5 Stars hotels in Historic Route 66\. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Historic Route 66 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Historic Route 66 hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Historic Route 66 without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Historic Route 66.

## Frequently asked questions

### How much does it cost to stay in a 5-star hotel in Historic Route 66?

> - Search for the lowest price per night from CA $159

### What makes a hotel 5 stars in Historic Route 66?

### Are there any 5-star all-inclusive resorts in Historic Route 66?

## Explore a world of travel with Expedia

- Lodging
- Flights
- Packages
- Cars
- Other
- More ways to book

- [5 Star Hotels in Quad Cities ](https://www.expedia.ca/5Star-Quad-Cities-Hotels.s50-0-d603001.Travel-Guide-Filter-Hotels)
- [Hotels near Lake Michigan ](https://www.expedia.ca/Lake-Michigan-Hotels.0-l6338716-0.Travel-Guide-Filter-Hotels)
- [Aparthotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Apart-Hotels.d6233674-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Bed-And-Breakfast.d6233674-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Cabin Rentals in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Cabins.d6233674-aaCabins.Travel-Guide-Accommodation)
- [Chalets in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Chalets.d6233674-aaChalets.Travel-Guide-Accommodation)
- [Condo Rentals in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Condos.d6233674-aaCondos.Travel-Guide-Accommodation)
- [Adults Only Resorts & in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Adults-Only-Resorts.0-0-d6233674-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [Beach Hotel Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Beach-Hotel.0-0-d6233674-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Best Western Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Best-Western.0-0-d6233674--bBestWestern.Travel-Guide-Filter-Hotels)
- [Boutique Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Boutique-Hotel.0-0-d6233674-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Cheap-Hotels.0-0-d6233674-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Golf Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Golf-Hotel.0-0-d6233674-tGolfHotel.Travel-Guide-Filter-Hotels)
- [Historic Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Historic-Hotel.0-0-d6233674-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotel-With-Pool.0-0-d6233674-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Hotels with Balconies in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotels-With-Balconies.0-0-d6233674-tHotelswithBalconies.Travel-Guide-Filter-Hotels)
- [Hotels with Waterslides in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotels-With-Waterslides.0-0-d6233674-tHotelswithWaterslides.Travel-Guide-Filter-Hotels)
- [Lake Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Lake-Hotels.0-0-d6233674-tLakeHotels.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Luxury-Hotel.0-0-d6233674-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Marriott Hotels & Resorts in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Marriott-Hotels-Resorts.0-0-d6233674--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels)
- [Motel 6 Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Motel-6.0-0-d6233674--bMotel6.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Pet-Friendly-Hotel.0-0-d6233674-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Romantic-Hotel.0-0-d6233674-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Spa Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Spa-Hotel.0-0-d6233674-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Waterpark Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Waterpark-Hotels.0-0-d6233674-tWaterparkHotels.Travel-Guide-Filter-Hotels)
- [Ohio River Valley Hotels ](https://www.expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)
- [Treehouses in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Treehouses.d6233674-aaTreehouses.Travel-Guide-Accommodation)
- [B&B in Quad Cities ](https://www.expedia.ca/Quad-Cities-Bed-And-Breakfast.d603001-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Cabin Rentals in Quad Cities ](https://www.expedia.ca/Quad-Cities-Cabins.d603001-aaCabins.Travel-Guide-Accommodation)
- [Best Western Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Best-Western.0-0-d603001--bBestWestern.Travel-Guide-Filter-Hotels)
- [Boutique Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Boutique-Hotel.0-0-d603001-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
- [Casino Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Casino-Hotel.0-0-d603001-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Hotels & Resorts for Couples in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Couples-Resorts-Hotels.0-0-d603001-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Family Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Family-Hotel.0-0-d603001-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Historic Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Historic-Hotel.0-0-d603001-tHistoricHotel.Travel-Guide-Filter-Hotels)
- [Honeymoon Resorts and in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Honeymoon-Hotels.0-0-d603001-tHoneymoonHotels.Travel-Guide-Filter-Hotels)
- [Hotels with Early Check-in in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Early-Check-In.0-0-d603001-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Pool.0-0-d603001-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Hotels with Wifi in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Wifi.0-0-d603001-tHotelwithwifi.Travel-Guide-Filter-Hotels)
- [Hotels with Bar in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Bar.0-0-d603001-tHotelswithBar.Travel-Guide-Filter-Hotels)
- [Hotels with Free Airport Shuttle in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d603001-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
- [Hotels with Free Breakfast in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Free-Breakfast.0-0-d603001-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels)
- [Hotels with Hot Tubs in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Hot-Tubs.0-0-d603001-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
- [Hotels with an Indoor Pool in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Indoor-Pool.0-0-d603001-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Hotels with Kitchenettes in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Kitchenettes.0-0-d603001-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Luxury-Hotel.0-0-d603001-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Motel 6 Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Motel-6.0-0-d603001--bMotel6.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Pet-Friendly-Hotel.0-0-d603001-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Romantic-Hotel.0-0-d603001-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Spa Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Spa-Hotel.0-0-d603001-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Waterpark Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Waterpark-Hotels.0-0-d603001-tWaterparkHotels.Travel-Guide-Filter-Hotels)
- [Quad Cities Hotels ](https://www.expedia.ca/Quad-Cities-Hotels.d603001.Travel-Guide-Hotels)
- [B&B in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Bed-And-Breakfast.d6234151-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Americinn Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Americinn.0-0-d6234151--bAmericinn.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Luxury-Hotel.0-0-d6234151-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Pet-Friendly Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Pet-Friendly-Hotel.0-0-d6234151-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
- [Romantic Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Romantic-Hotel.0-0-d6234151-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Southeast Iowa Hotels ](https://www.expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)

- [Flights to Ohio River Valley ](https://www.expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)
- [Flights to Quad Cities ](https://www.expedia.ca/Cheap-Flights-To-Quad-Cities.d603001.Travel-Guide-Flights)
- [Flights to Southeast Iowa ](https://www.expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)
- [Flights from Calgary to Quad Cities ](https://www.expedia.ca/lp/flights/178245/603001/calgary-to-quad-cities)
- [Flights from Calgary to Ohio River Valley ](https://www.expedia.ca/lp/flights/178245/6233674/calgary-to-ohio-river-valley)
- [Flights from Chicago to Quad Cities ](https://www.expedia.ca/lp/flights/178248/603001/chicago-to-quad-cities)
- [Flights from Columbus to Quad Cities ](https://www.expedia.ca/lp/flights/178251/603001/columbus-to-quad-cities)
- [Flights from Dallas to Ohio River Valley ](https://www.expedia.ca/lp/flights/178253/6233674/dallas-to-ohio-river-valley)
- [Flights from Indianapolis to Quad Cities ](https://www.expedia.ca/lp/flights/178266/603001/indianapolis-to-quad-cities)
- [Flights from Miami to Ohio River Valley ](https://www.expedia.ca/lp/flights/178286/6233674/miami-to-ohio-river-valley)
- [Flights from Minneapolis - St. Paul to Quad Cities ](https://www.expedia.ca/lp/flights/178287/603001/minneapolis-st-paul-to-quad-cities)
- [Flights from Minneapolis - St. Paul to Ohio River Valley ](https://www.expedia.ca/lp/flights/178287/6233674/minneapolis-st-paul-to-ohio-river-valley)
- [Flights from Orlando to Ohio River Valley ](https://www.expedia.ca/lp/flights/178294/6233674/orlando-to-ohio-river-valley)
- [Flights from Seattle to Quad Cities ](https://www.expedia.ca/lp/flights/178307/603001/seattle-to-quad-cities)
- [Flights from Toronto to Quad Cities ](https://www.expedia.ca/lp/flights/178314/603001/toronto-to-quad-cities)
- [Flights from Toronto to Ohio River Valley ](https://www.expedia.ca/lp/flights/178314/6233674/toronto-to-ohio-river-valley)
- [Flights from Vancouver to Ohio River Valley ](https://www.expedia.ca/lp/flights/178315/6233674/vancouver-to-ohio-river-valley)
- [Flights from Edmonton to Quad Cities ](https://www.expedia.ca/lp/flights/180002/603001/edmonton-to-quad-cities)
- [Flights from Edmonton to Ohio River Valley ](https://www.expedia.ca/lp/flights/180002/6233674/edmonton-to-ohio-river-valley)
- [Flights from Québec City to Ohio River Valley ](https://www.expedia.ca/lp/flights/180017/6233674/quebec-city-to-ohio-river-valley)
- [Flights from Amarillo to Quad Cities ](https://www.expedia.ca/lp/flights/371/603001/amarillo-to-quad-cities)
- [Flights from Hamilton to Quad Cities ](https://www.expedia.ca/lp/flights/3963/603001/hamilton-to-quad-cities)
- [Flights from Fort Lauderdale to Ohio River Valley ](https://www.expedia.ca/lp/flights/601750/6233674/fort-lauderdale-to-ohio-river-valley)
- [Flights from Newark to Ohio River Valley ](https://www.expedia.ca/lp/flights/601760/6233674/newark-to-ohio-river-valley)
- [Flights from Buffalo to Quad Cities ](https://www.expedia.ca/lp/flights/602674/603001/buffalo-to-quad-cities)
- [Flights from Buffalo to Ohio River Valley ](https://www.expedia.ca/lp/flights/602674/6233674/buffalo-to-ohio-river-valley)
- [Flights from Birmingham to Ohio River Valley ](https://www.expedia.ca/lp/flights/602981/6233674/birmingham-to-ohio-river-valley)
- [Flights from Quad Cities ](https://www.expedia.ca/lp/flights/603001/flights-from-quad-cities)
- [Flights from Winnipeg to Quad Cities ](https://www.expedia.ca/lp/flights/6141041/603001/winnipeg-to-quad-cities)
- [Flights from Ohio River Valley ](https://www.expedia.ca/lp/flights/6233674/flights-from-ohio-river-valley)

- [Lake Michigan ](https://www.expedia.ca/Lake-Michigan-United-States-of-America.d6338716.Vacation-Attraction)
- [Visit Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley.dx6233674)
- [Quad Cities Vacations ](https://www.expedia.ca/Quad-Cities.d603001.Destination-Travel-Guides)
- [Visit Quad Cities ](https://www.expedia.ca/Quad-Cities.dx603001)
- [Visit Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa.dx6234151)

- [Ace Rental Cars in Quad Cities ](https://www.expedia.ca/Ace-Car-Rentals-In-Quad-Cities.d603001-c2.Car-Rental-Guide-Suppliers)
- [Advantage Rent-A-Car Rental Cars in Ohio River Valley ](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Ohio-River-Valley.d6233674-c3.Car-Rental-Guide-Suppliers)
- [Avis Rental Cars in Quad Cities ](https://www.expedia.ca/Avis-Car-Rentals-In-Quad-Cities.d603001-c41.Car-Rental-Guide-Suppliers)
- [Car rentals near Quad Cities ](https://www.expedia.ca/Car-Rentals-In-Quad-Cities.d603001.Car-Rental-Guide)
- [Pickup Car Rentals in Ohio River Valley ](https://www.expedia.ca/Pickup-Car-Rentals-In-Ohio-River-Valley.d6233674-tPickup.Car-Rental-Guide-Class)
- [Thrifty Car Rental Rental Cars in Ohio River Valley ](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Ohio-River-Valley.d6233674-c45.Car-Rental-Guide-Suppliers)

- [Things to do in Quad Cities ](https://www.expedia.ca/Things-To-Do-In-Quad-Cities.d603001.Travel-Guide-Activities)

- [Book 5 Star Hotels in Historic Route 66 on Expedia.com ](https://www.expedia.com/5Star-Historic-Route-66-Hotels.s50-0-d702654640613646336.Travel-Guide-Filter-Hotels)