Book The Best Hotels in Southeast Iowa for 2026 from CA $92 - Fully Refundable Options

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

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Go beyond your typical stay in Southeast Iowa

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Our top choices for Southeast Iowa hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

A hotel room with two beds, a television, a desk with a lamp, and a chair.

A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Elaine

CA $145

CA $162 total

includes taxes & fees

Sep 6 - Sep 7

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".

An indoor swimming pool with clear water, surrounded by a white fence, and equipped with multiple entry points and seating areas.

A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.

2. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Lloyd

CA $131

CA $147 total

includes taxes & fees

Sep 20 - Sep 21

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

An indoor swimming pool with wooden walls and a balcony.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

3. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

Valerie

CA $117

CA $130 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

4. Best Western Mt. Pleasant Inn

Mount Pleasant

Anthony

CA $108

CA $121 total

includes taxes & fees

Sep 13 - Sep 14

An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.

A guest registration area with a counter, informational signs, and various items on shelves.

A brick building with a sign for Nauvoo Family Inn & Suites, featuring a traditional design with a tower and arched windows.

A hotel room with a bed, bedside lamps, a nightstand, a refrigerator, and a wooden headboard.

5. The Inn at Old Nauvoo

Nauvoo

Myles

CA $169

CA $191 total

includes taxes & fees

Sep 5 - Sep 6

A hotel room with two beds, a large wall-mounted picture, a desk with a lamp, and a window with curtains.

A staircase leading to a room with a black leather sofa, a framed picture on the wall, and a poster advertising an auction.

A hotel corridor with patterned carpet, doors on both sides, and an EXIT sign above the right door.

A hotel lobby with a reception desk, seating area, staircase, and a framed welcome sign.

6. Super 8 by Wyndham Keokuk

Keokuk

"Staff was friendly. Breakfast buffet included make your own waffles, bagels with cream cheese or peanut butter, cereal, and muffins. Our main issue was just that the exercise room was closed and looked like it was being used for storage. If we had known that I probably would have booked somewhere else. Also the internet was down one morning. When I contacted the front desk she said she would let someone know but she had just started last week so she didn’t know how to reset the modem. It was...

Patrick

CA $100

CA $112 total

includes taxes & fees

Sep 4 - Sep 5

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A multi-story hotel with a central entrance, a parking lot, and a clear sky.

A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.

A spa area with a hot tub, wooden ceiling, and tiled walls.

7. Quality Inn & Suites Keokuk North

Keokuk

Susan

CA $149

CA $166 total

includes taxes & fees

Oct 4 - Oct 5

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

A compact kitchen with wooden cabinets, a microwave, a coffee maker, and a dishwasher.

8. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

CA $199

CA $211 total

includes taxes & fees

Sep 6 - Sep 7

A room with a large window, a sofa, and a chair.

A living room with a flat-screen TV on a white console, a grey sofa, and a framed picture on the wall.

A brick building with a balcony, a staircase, and a sign reading "Zions Mercantile".

A bedroom with two beds, a ceiling fan, a TV, and a dresser.

9. Nauvoo Temple House Hotel

Nauvoo

Andrew

CA $171

CA $201 total

includes taxes & fees

Oct 3 - Oct 4

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

A Hampton Inn hotel with a covered entrance, a well-lit facade, and a landscaped front yard.

A reception desk with a "Welcome to the Hawk Eye State" sign, a digital kiosk, and a "Manager On Duty" sign.

10. Hampton Inn Keokuk

Keokuk

Mark

CA $153

CA $171 total

includes taxes & fees

Sep 27 - Sep 28

A patio area with Adirondack chairs and a central fire pit.

A snack and sundries section with shelves stocked with various products, a chalkboard with 'Snack!' written on it, and a 'Treats' sign above a display case.

A modern hotel with a brick facade, large windows, and a covered entrance.

A spacious dining area with multiple tables and chairs, a television on a shelf, and a large chandelier.

11. Hampton Inn & Suites Burlington

Burlington

Brian

CA $170

CA $202 total

includes taxes & fees

Sep 17 - Sep 18

A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

A multi-story hotel with a covered entrance and a landscaped lawn.

A bathroom with a marble-tiled wall, a large bathtub, a wooden vanity with a television, and a patterned rug.

A lobby with a reception desk, red patterned seating, a round beige ottoman, and a potted plant.

12. Quality Inn & Suites Mount Pleasant

Mount Pleasant

Laura

CA $99

CA $111 total

includes taxes & fees

Oct 4 - Oct 5

A bedroom with a bed, a wooden headboard, a nightstand, a lamp, a rug, and a door.

A stone building with a wooden door, illuminated by exterior lighting.

A staircase with a patterned carpet and wooden balusters.

A dining area with a round table set for four, a wooden cabinet, and a kitchen area with shelves stocked with kitchenware.

13. Willard Richards Inn

Nauvoo

Dr. Shawn

CA $320

CA $383 total

includes taxes & fees

Sep 8 - Sep 9

A park bench and a lamppost with flowers in the foreground.

A dining table with plates of food, candles, and a lamp.

A tree with yellow leaves in front of a brick building.

A two-story brick building with a green porch and a pathway leading to the entrance.

14. Nauvoo Grand Bed & Breakfast

Nauvoo

Henze

CA $241

CA $272 total

includes taxes & fees

Sep 5 - Sep 6

A well-lit indoor swimming pool with wooden walls and ceiling, surrounded by lounge chairs and umbrellas.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A hotel with a covered entrance, a parking lot, and a sign indicating it is an Embassy Suites location.

A spacious lobby with a high ceiling, wooden staircase, and a reception desk.

15. AmericInn by Wyndham West Burlington

West Burlington

Jacqueline

CA $92

CA $103 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with two beds, a desk, a chair, and a large window.

A small, clean room with a kitchenette, a coffee machine, a microwave, and a TV mounted on the wall. There are two tables and chairs, and a window providing natural light.

A bathroom with a bathtub, toilet, and sink.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

16. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

CA $109

CA $122 total

includes taxes & fees

Sep 13 - Sep 14

A compact hotel room with a kitchenette, a bed with a patterned bedspread, and a small sitting area with a table and chair.

A compact kitchenette with a microwave, a small refrigerator, a metal drying rack, and a white air conditioning unit.

A hotel room with a bed, a desk with a chair, a microwave, a stove, and a refrigerator.

A bathroom with a toilet, sink, and shower.

17. Chief Motel

Keokuk

RONALD

CA $87

CA $98 total

includes taxes & fees

Sep 5 - Sep 6

A large, two-story house with a porch, surrounded by lush green lawns and trees.

A living room with a dark wall, a chandelier, a fireplace, and a large clock.

A black fireplace with a TV above it, a chandelier, and a door leading to another room.

A bedroom with two beds, each with a headboard, a nightstand, and a wall-mounted lamp.

18. Evans Holly Grove Inn B&B

Burlington

Alisa

CA $156

CA $175 total

includes taxes & fees

Sep 27 - Sep 28

A water park with multiple slides and inflatable tubes.

A casino interior with multiple gaming tables, a central bar area, and a distinctive circular ceiling design.

A restaurant with multiple screens displaying sports events, booths, and tables with menus.

A spacious lobby with multiple seating areas, decorative lighting, and potted plants.

19. Fun City Resort Hotel

Burlington

Jamie

CA $148

CA $175 total

includes taxes & fees

Sep 22 - Sep 23

A compact kitchen with a microwave, stove, and sink. There is a cabinet with a mirror above the sink and a small shelf above the microwave. The kitchen has a tiled floor and yellow walls.

A small bathroom with a sink, mirror, and a microwave.

A compact kitchen with a built-in microwave, stove, and sink.

A hotel room with two beds, a desk with a chair, a TV, a desk lamp, a microwave, and a painting on the wall.

20. Budget Inn

Keokuk

Deanna

CA $87

CA $98 total

includes taxes & fees

Oct 2 - Oct 3

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Stay near popular Southeast Iowa attractions

Historic Nauvoo

9.6/10 (269 reviews)

Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.

See properties

Snake Alley

8.6/10 (172 reviews)

Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.

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Lacey-Keosauqua State Park

8.6/10 (15 reviews)

Commune with nature and explore the great outdoors at Lacey-Keosauqua State Park during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

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Iowa State Penitentiary

7.2/10 (40 reviews)

After visiting Iowa State Penitentiary, make a plan to see the other sights and activities in Fort Madison. Wander the riverfront in this family-friendly area.

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Fort Madison Marina

7.6/10 (12 reviews)

Explore the waterfront in Fort Madison with a trip to Fort Madison Marina. Wander the riverfront in this family-friendly area.

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Baxter's Vineyards

7.4/10 (23 reviews)

You can enjoy a tasting or tour at Baxter's Vineyards during your travels to Nauvoo. While you're in the area, stroll along the riverfront.

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Lake Sugema

7.0/10 (2 reviews)

Commune with nature and explore the great outdoors at Lake Sugema during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

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North Lee County Historical Society

7.6/10 (17 reviews)

You can browse the exhibits at North Lee County Historical Society, a museum with a storied past, during your travels to Fort Madison. While you're in the area, stroll along the riverfront.

See properties

Learn more about Southeast Iowa

Experience the family-friendly area of Southeast Iowa—a scenic riverfront, shopping, and sights from Bentonsport National Historic District to Geode State Park.

See all hotels in Southeast Iowa

A steel bridge over a river with a stone wall on the right.

Top Southeast Iowa Hotel Reviews

AmericInn by Wyndham West Burlington

8/10 Good

"Well maintained."

Quality Inn & Suites Keokuk North

10/10 Excellent

"I've stayed here a bunch of times over the last several years. Never had an issue. Property is clean, area is quiet, rooms have plenty of space and beds are comfortable. Breakfast is nothing special (typical hotel breakfast), but does the job. Will stay here again in the future."

Fun City Resort Hotel

10/10 Excellent

"Check in was super fast and easy, staff were friendly and helpful. Will definitely be back."

Nauvoo Vacation Villas & Condos

10/10 Excellent

"A great place to stay!"

Great River Hotel

10/10 Excellent

"Great hotel with lots to do"

Quality Inn & Suites Fort Madison near Hwy 61

10/10 Excellent

"The room was very clean and check in went great…. Staff were very friendly and the wife and I will definitely be staying again on our next visit…."

Hampton Inn & Suites Burlington

10/10 Excellent

"Very nice big room enjoyed our stay."

Cobblestone Inn & Suites - Fort Madison

10/10 Excellent

"As always, a great stay."

Baymont by Wyndham Keokuk

8/10 Good

"Met our needs. Good location. Room was clean."

More cheap stays in Southeast Iowa

Baymont by Wyndham Keokuk

325 Main St Keokuk IA

CA $103

CA $115 total

Sep 4 - Sep 5

includes taxes & fees

6.2/10 (559 reviews)

Best Western Mt. Pleasant Inn

810 N Grand Avenue Mount Pleasant IA

CA $108

CA $121 total

Sep 13 - Sep 14

includes taxes & fees

8.2/10 Very good! (879 reviews)

Quality Inn & Suites Fort Madison near Hwy 61

6169 Reve Ct Fort Madison IA

CA $131

CA $147 total

Sep 20 - Sep 21

includes taxes & fees

8.6/10 Excellent! (644 reviews)

Quality Inn & Suites Keokuk North

3404 Main St Keokuk IA

CA $149

CA $166 total

Oct 4 - Oct 5

includes taxes & fees

8.6/10 Excellent! (840 reviews)

Comfort Suites Burlington

1780 Stonegate Center Dr Burlington IA

CA $159

CA $186 total

Oct 4 - Oct 5

includes taxes & fees

The Inn at Old Nauvoo

1875 Mulholland St Nauvoo IL

CA $169

CA $191 total

Sep 5 - Sep 6

includes taxes & fees

Hotels in Southeast Iowa with star rating

Explore a world of travel with Expedia

Book Hotels in Southeast Iowa on Expedia.com

Find hotels in Southeast Iowa from CA $92

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southeast Iowa

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southeast Iowa hotels

1. Cobblestone Inn & Suites - Fort Madison

2. Quality Inn & Suites Fort Madison near Hwy 61

3. AmericInn by Wyndham Mount Pleasant

4. Best Western Mt. Pleasant Inn

5. The Inn at Old Nauvoo

6. Super 8 by Wyndham Keokuk

7. Quality Inn & Suites Keokuk North

8. Nauvoo Vacation Villas & Condos

9. Nauvoo Temple House Hotel

10. Hampton Inn Keokuk

11. Hampton Inn & Suites Burlington

12. Quality Inn & Suites Mount Pleasant

13. Willard Richards Inn

14. Nauvoo Grand Bed & Breakfast

15. AmericInn by Wyndham West Burlington

16. Super 8 by Wyndham Mt Pleasant

17. Chief Motel

18. Evans Holly Grove Inn B&B

19. Fun City Resort Hotel

20. Budget Inn

Stay near popular Southeast Iowa attractions

Historic Nauvoo

Snake Alley

Lacey-Keosauqua State Park

Iowa State Penitentiary

Fort Madison Marina

Baxter's Vineyards

Lake Sugema

North Lee County Historical Society

Learn more about Southeast Iowa

Top Southeast Iowa Hotel Reviews

AmericInn by Wyndham West Burlington

Quality Inn & Suites Keokuk North

Fun City Resort Hotel

Nauvoo Vacation Villas & Condos

Great River Hotel

Quality Inn & Suites Fort Madison near Hwy 61

Hampton Inn & Suites Burlington

Cobblestone Inn & Suites - Fort Madison

Baymont by Wyndham Keokuk

More cheap stays in Southeast Iowa

Baymont by Wyndham Keokuk

Best Western Mt. Pleasant Inn

Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Keokuk North

Comfort Suites Burlington

The Inn at Old Nauvoo

Hotels in Southeast Iowa with star rating

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