Central United States Vacation Packages

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Your Central United States Vacation

When it's time to set off on your next unforgettable adventure, a vacation package to Central United States is the answer. From this destination's friendly locals to all the other incredible things it's renowned for, there's a lot to discover. With so much to see and do on a trip to Central United States, it can be difficult to know where to begin. Kick off your travels in New York at Times Square and Central Park — two leading attractions here. Another great city worthy of a spot on your itinerary is Orlando. Don't miss Universal Studios Florida and Orlando International Premium Outlets. From the moment you book your Central United States vacation to when you return home, Expedia has your back every step of the way.

Top Central United States Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Casa Duro
The Royal Sonesta Chicago River North
Level Chicago – Old Town
Trump International Hotel & Tower Chicago
Park Hyatt Chicago

Where to stay in Central United States

Find the best Central United States areas and neighborhoods for the activities you enjoy most. Learn more about Central United States

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Central United States Hotel Deals

The Wade

The Wade

4.5 out of 5
644 N Lake Shore Dr, Chicago, IL
Fully refundableReserve now, pay when you stay
The price is CA $207 per night from Sep 4 to Sep 5
CA $207
CA $244 total
Sep 4 - Sep 5
includes taxes & fees
8.2/10 Very Good! (1,226 reviews)
"It was very close to navy pier where it was just a 10 min way. And had a great view from our room. Facing the lake"

Reviewed on Aug. 27, 2025

The Wade
Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue, Chicago, IL
Fully refundableReserve now, pay when you stay
The price is CA $194 per night from Sep 1 to Sep 2
CA $194
CA $228 total
Sep 1 - Sep 2
includes taxes & fees
7.8/10 Good! (9,045 reviews)
"Very convenient to South Loop sites!"

Reviewed on Aug. 26, 2025

Congress Plaza Hotel
Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North

4 out of 5
600 N State St, Chicago, IL
The price is CA $231 per night from Sep 3 to Sep 4
CA $231
CA $271 total
Sep 3 - Sep 4
includes taxes & fees
8.4/10 Very Good! (4,802 reviews)
"Very nice,everything is around.Highly recommend."

Reviewed on Aug. 27, 2025

Embassy Suites by Hilton Chicago Downtown River North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Central United States

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.