A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Southeast Iowa Vacation Rentals

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Our top choices for Southeast Iowa vacation rentals

1. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (449 reviews)
"A great place to stay!"
United States
Renae
The price is CA $203
CA $215 total
includes taxes & fees
Oct 4 - Oct 5
Nauvoo Vacation Villas & Condos

2. Riverfront Cabin With Small Beach Short Drive From Nauvoo

Riverfront Cabin With Small Beach Short Drive From Nauvoo
Niota
8.2 out of 10, Very good, (55 reviews)
"This was such a great getaway spot! We needed peace and we got it."
United States
Anonymous traveller
The price is CA $75
CA $147 total
includes taxes & fees
Oct 19 - Oct 20
Riverfront Cabin With Small Beach Short Drive From Nauvoo

3. Stay in this Unique SE Iowa Apt

Stay in this Unique SE Iowa Apt
Fort Madison
10.0 out of 10, Exceptional, (18 reviews)
"Fun stay. Adorned with penitentiary history that was very interesting. Across from a beautiful river view and park."
United States
Taylor D.
The price is CA $74
CA $193 total
includes taxes & fees
Sep 28 - Sep 29
Stay in this Unique SE Iowa Apt

4. Charming One Bedroom home in Keosauqua near shops

Charming One Bedroom home in Keosauqua near shops
Keosauqua
9.2 out of 10, Wonderful, (15 reviews)
"Quiet, clean and comfortable. Nicely appointed. We saw a deer and a turkey when we stepped out of the house Sunday morning. Good communications. "
United States
Melinda L.
The price is CA $117
CA $226 total
includes taxes & fees
Sep 27 - Sep 28
Charming One Bedroom home in Keosauqua near shops

5. "THE SHOP" retro 60's

"THE SHOP" retro 60's
Keosauqua
10.0 out of 10, Exceptional, (68 reviews)
"Beautiful property and excellent communication!"
United States
Calicia
The price is CA $134
CA $212 total
includes taxes & fees
Oct 7 - Oct 8
"THE SHOP" retro 60's

6. Fairy Bowery

Fairy Bowery
Nauvoo
8.2 out of 10, Very good, (68 reviews)
"Great price for the area. "
United States
Brian
The price is CA $106
CA $187 total
includes taxes & fees
Oct 6 - Oct 7
Fairy Bowery

7. View Nauvoo and the Mighty Mississippi/Sidon

View Nauvoo and the Mighty Mississippi/Sidon
Nauvoo
9.6 out of 10, Exceptional, (44 reviews)
"Castle home was amazing! View of the river is incredible. So much room with extra fans and pillows. We loved our stay!!"
United States
Chris P.
The price is CA $132
CA $414 total
includes taxes & fees
Sep 27 - Sep 28
View Nauvoo and the Mighty Mississippi/Sidon

8. Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo

Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo
Nauvoo
9.8 out of 10, Exceptional, (25 reviews)
"Charming little property on the Main Street into Nauvoo. It was comfortable and cozy. We enjoyed walking into the historical area and to the temple. I would stay again. Easy check-in after great communication. Many thanks to our host."
United States
CoolDave88
The price is CA $158
CA $291 total
includes taxes & fees
Sep 28 - Sep 29
Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo

9. Mulholland Garden Apartment

Mulholland Garden Apartment
Nauvoo
9.2 out of 10, Wonderful, (48 reviews)
"Very good location, sofa bed mattress was uncomfortable, there are stairs to the bathroom."
United States
Carol
The price is CA $98
CA $179 total
includes taxes & fees
Oct 6 - Oct 7
Mulholland Garden Apartment

10. Nauvoo Windmill Farmhouse 10-12 people

Nauvoo Windmill Farmhouse 10-12 people
Niota
10.0 out of 10, Exceptional, (21 reviews)
"Great stay very peaceful "
United States
larry r.
The price is CA $176
CA $311 total
includes taxes & fees
Oct 7 - Oct 8
Nauvoo Windmill Farmhouse 10-12 people

11. Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.

Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.
Nauvoo
9.8 out of 10, Exceptional, (10 reviews)
"So close to the temple and other historical sites! Unique experience for sure."
United States
Ryan
The price is CA $159
CA $283 total
includes taxes & fees
Sep 26 - Sep 27
Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.

12. Relax on the River and Enjoy Southeast Iowa's Beauty

Relax on the River and Enjoy Southeast Iowa's Beauty
Keosauqua
9.8 out of 10, Exceptional, (190 reviews)
"Clean, cozy, and had everything we needed for a little cabin get away with our family! The area had a lot of great things to do and we enjoyed the state park so close by. "
United States
Morgan H.
The price is CA $163
CA $252 total
includes taxes & fees
Sep 28 - Sep 29
Relax on the River and Enjoy Southeast Iowa's Beauty

13. Nauvoo Country Cottage - Sleeps 12

Nauvoo Country Cottage - Sleeps 12
Niota
9.6 out of 10, Exceptional, (94 reviews)
"Stayed here multiple times. Quiet, close to Nauvoo, plenty of space. Always a solid stay!"
United States
Tim H.
The price is CA $212
CA $356 total
includes taxes & fees
Oct 5 - Oct 6
Nauvoo Country Cottage - Sleeps 12

14. Private Woodsy Cabin close to River and Keosauqua

Private Woodsy Cabin close to River and Keosauqua
Keosauqua
9.8 out of 10, Exceptional, (21 reviews)
"Perfect location !! Lovely place and I can't say enough about how much we loved their turkey!"
United States
Julie
The price is CA $165
CA $280 total
includes taxes & fees
Sep 28 - Sep 29
Private Woodsy Cabin close to River and Keosauqua

15. Historic Nauvoo Apartment, family friendly.

Historic Nauvoo Apartment, family friendly.
Nauvoo
8.6 out of 10, Excellent, (17 reviews)
"Convenient for walking to sites of interest."
United States
Derek H.
The price is CA $164
CA $280 total
includes taxes & fees
Sep 27 - Sep 28
Historic Nauvoo Apartment, family friendly.

16. 5 Minutes to Downtown Nauvoo - Great Spot for Young Families - Some Stairs

5 Minutes to Downtown Nauvoo - Great Spot for Young Families - Some Stairs
Nauvoo
9.6 out of 10, Exceptional, (27 reviews)
"Clean, close to shopping and sites. Owner was easy to work with."
United States
Lyndsay M.
The price is CA $175
CA $337 total
includes taxes & fees
Oct 8 - Oct 9
5 Minutes to Downtown Nauvoo - Great Spot for Young Families - Some Stairs

17. PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets

PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets
Nauvoo
9.4 out of 10, Exceptional, (13 reviews)
"Can’t say enough about the stunning view of the Mississippi River from every part of the home! The home was extremely comfortable for the two of us. We really enjoyed our stay!"
United States
Debbie L.
The price is CA $203
CA $460 total
includes taxes & fees
Oct 8 - Oct 9
PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets

18. Hayfield Cabin

Hayfield Cabin
Niota
6.8 out of 10, (5 reviews)
"It looked like someone was living there. And saw someone lurking around the outside of the cabin. "
United States
Anthony P.
The price is CA $107
CA $189 total
includes taxes & fees
Sep 27 - Sep 28
Hayfield Cabin

19. Grand Victorian on the Mississippi

Grand Victorian on the Mississippi
Fort Madison
9.8 out of 10, Exceptional, (33 reviews)
"The home was beautifully decorated! We enjoyed our stay."
United States
Theresa G.
The price is CA $274
CA $616 total
includes taxes & fees
Oct 7 - Oct 8
Grand Victorian on the Mississippi

20. The Red Front Suite - Sleeps 15

The Red Front Suite - Sleeps 15
Nauvoo
9.8 out of 10, Exceptional, (95 reviews)
"Great location, comfortable beds."
United States
Diane P.
The price is CA $212
CA $380 total
includes taxes & fees
Sep 28 - Sep 29
The Red Front Suite - Sleeps 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Iowa Hotel Reviews

Find out more about Southeast Iowa

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Southeast Iowa. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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