Title: Car Rental Historic Route 66 - Expedia.ca [Historic Route 66 Travel Guide](https://expedia.ca/Historic-Route-66.dx702654640613646336)[Hotels in Historic Route 66](https://expedia.ca/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Flights to Historic Route 66](https://expedia.ca/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Vacation Packages](https://expedia.ca/Historic-Route-66.d702654640613646336.Destination-Travel-Guides) ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in Historic Route 66 \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Historic Route 66, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Historic%20Route%2066,%20United%20States%20of%20America&dpln=702654640613646336&date1=05/01/2026&date2=07/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Historic Route 66, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Historic%20Route%2066,%20United%20States%20of%20America&dpln=702654640613646336&date1=05/01/2026&date2=07/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Historic Route 66, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Historic%20Route%2066,%20United%20States%20of%20America&dpln=702654640613646336&date1=05/01/2026&date2=07/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Historic Route 66, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Historic%20Route%2066,%20United%20States%20of%20America&dpln=702654640613646336&date1=05/01/2026&date2=07/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Historic Route 66 [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Historic%20Route%2066,%20United%20States%20of%20America&dpln=702654640613646336&date1=05/01/2026&date2=07/01/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### What happens if I need to cancel my Historic Route 66 car reservation? ### How do I find the best car rental deals in Historic Route 66 with Expedia? ### How old do you have to be to rent a car in Historic Route 66? ### What do you need to rent a car in Historic Route 66? ### Can I rent a car for a month or longer in Historic Route 66? ### Where can I find a Historic Route 66 car rental if I am younger than 25? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [5 Star Hotels in Quad Cities ](https://www.expedia.ca/5Star-Quad-Cities-Hotels.s50-0-d603001.Travel-Guide-Filter-Hotels) - [Hotels near Lake Michigan ](https://www.expedia.ca/Lake-Michigan-Hotels.0-l6338716-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Apart-Hotels.d6233674-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Bed-And-Breakfast.d6233674-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Cabins.d6233674-aaCabins.Travel-Guide-Accommodation) - [Chalets in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Chalets.d6233674-aaChalets.Travel-Guide-Accommodation) - [Condo Rentals in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Condos.d6233674-aaCondos.Travel-Guide-Accommodation) - [Adults Only Resorts & in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Adults-Only-Resorts.0-0-d6233674-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Hotel Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Beach-Hotel.0-0-d6233674-tBeachHotel.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Best-Western.0-0-d6233674--bBestWestern.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Boutique-Hotel.0-0-d6233674-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Cheap-Hotels.0-0-d6233674-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Golf-Hotel.0-0-d6233674-tGolfHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Historic-Hotel.0-0-d6233674-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotel-With-Pool.0-0-d6233674-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotels-With-Balconies.0-0-d6233674-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with Waterslides in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Hotels-With-Waterslides.0-0-d6233674-tHotelswithWaterslides.Travel-Guide-Filter-Hotels) - [Lake Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Lake-Hotels.0-0-d6233674-tLakeHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Luxury-Hotel.0-0-d6233674-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Marriott-Hotels-Resorts.0-0-d6233674--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Motel-6.0-0-d6233674--bMotel6.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Pet-Friendly-Hotel.0-0-d6233674-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Romantic-Hotel.0-0-d6233674-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Spa-Hotel.0-0-d6233674-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Hotels-Waterpark-Hotels.0-0-d6233674-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Ohio River Valley Hotels ](https://www.expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels) - [Treehouses in Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley-Treehouses.d6233674-aaTreehouses.Travel-Guide-Accommodation) - [B&B in Quad Cities ](https://www.expedia.ca/Quad-Cities-Bed-And-Breakfast.d603001-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Quad Cities ](https://www.expedia.ca/Quad-Cities-Cabins.d603001-aaCabins.Travel-Guide-Accommodation) - [Best Western Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Best-Western.0-0-d603001--bBestWestern.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Boutique-Hotel.0-0-d603001-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Casino-Hotel.0-0-d603001-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Couples-Resorts-Hotels.0-0-d603001-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Family-Hotel.0-0-d603001-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Historic-Hotel.0-0-d603001-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Honeymoon-Hotels.0-0-d603001-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Early-Check-In.0-0-d603001-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Pool.0-0-d603001-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Wifi in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotel-With-Wifi.0-0-d603001-tHotelwithwifi.Travel-Guide-Filter-Hotels) - [Hotels with Bar in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Bar.0-0-d603001-tHotelswithBar.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d603001-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Free-Breakfast.0-0-d603001-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Hot-Tubs.0-0-d603001-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Indoor-Pool.0-0-d603001-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Hotels-With-Kitchenettes.0-0-d603001-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Luxury-Hotel.0-0-d603001-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Motel-6.0-0-d603001--bMotel6.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Pet-Friendly-Hotel.0-0-d603001-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Romantic-Hotel.0-0-d603001-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Spa-Hotel.0-0-d603001-tSpaHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Quad Cities ](https://www.expedia.ca/Quad-Cities-Hotels-Waterpark-Hotels.0-0-d603001-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Quad Cities Hotels ](https://www.expedia.ca/Quad-Cities-Hotels.d603001.Travel-Guide-Hotels) - [B&B in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Bed-And-Breakfast.d6234151-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Americinn Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Americinn.0-0-d6234151--bAmericinn.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Luxury-Hotel.0-0-d6234151-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Pet-Friendly-Hotel.0-0-d6234151-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Romantic-Hotel.0-0-d6234151-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Southeast Iowa Hotels ](https://www.expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels) - [Flights to Ohio River Valley ](https://www.expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights) - [Flights to Quad Cities ](https://www.expedia.ca/Cheap-Flights-To-Quad-Cities.d603001.Travel-Guide-Flights) - [Flights to Southeast Iowa ](https://www.expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights) - [Flights from Calgary to Quad Cities ](https://www.expedia.ca/lp/flights/178245/603001/calgary-to-quad-cities) - [Flights from Calgary to Ohio River Valley ](https://www.expedia.ca/lp/flights/178245/6233674/calgary-to-ohio-river-valley) - [Flights from Chicago to Quad Cities ](https://www.expedia.ca/lp/flights/178248/603001/chicago-to-quad-cities) - [Flights from Columbus to Quad Cities ](https://www.expedia.ca/lp/flights/178251/603001/columbus-to-quad-cities) - [Flights from Dallas to Ohio River Valley ](https://www.expedia.ca/lp/flights/178253/6233674/dallas-to-ohio-river-valley) - [Flights from Indianapolis to Quad Cities ](https://www.expedia.ca/lp/flights/178266/603001/indianapolis-to-quad-cities) - [Flights from Miami to Ohio River Valley ](https://www.expedia.ca/lp/flights/178286/6233674/miami-to-ohio-river-valley) - [Flights from Minneapolis - St. Paul to Quad Cities ](https://www.expedia.ca/lp/flights/178287/603001/minneapolis-st-paul-to-quad-cities) - [Flights from Minneapolis - St. Paul to Ohio River Valley ](https://www.expedia.ca/lp/flights/178287/6233674/minneapolis-st-paul-to-ohio-river-valley) - [Flights from Orlando to Ohio River Valley ](https://www.expedia.ca/lp/flights/178294/6233674/orlando-to-ohio-river-valley) - [Flights from Seattle to Quad Cities ](https://www.expedia.ca/lp/flights/178307/603001/seattle-to-quad-cities) - [Flights from Toronto to Quad Cities ](https://www.expedia.ca/lp/flights/178314/603001/toronto-to-quad-cities) - [Flights from Toronto to Ohio River Valley ](https://www.expedia.ca/lp/flights/178314/6233674/toronto-to-ohio-river-valley) - [Flights from Vancouver to Ohio River Valley ](https://www.expedia.ca/lp/flights/178315/6233674/vancouver-to-ohio-river-valley) - [Flights from Edmonton to Quad Cities ](https://www.expedia.ca/lp/flights/180002/603001/edmonton-to-quad-cities) - [Flights from Edmonton to Ohio River Valley ](https://www.expedia.ca/lp/flights/180002/6233674/edmonton-to-ohio-river-valley) - [Flights from Québec City to Ohio River Valley ](https://www.expedia.ca/lp/flights/180017/6233674/quebec-city-to-ohio-river-valley) - [Flights from Amarillo to Quad Cities ](https://www.expedia.ca/lp/flights/371/603001/amarillo-to-quad-cities) - [Flights from Hamilton to Quad Cities ](https://www.expedia.ca/lp/flights/3963/603001/hamilton-to-quad-cities) - [Flights from Fort Lauderdale to Ohio River Valley ](https://www.expedia.ca/lp/flights/601750/6233674/fort-lauderdale-to-ohio-river-valley) - [Flights from Newark to Ohio River Valley ](https://www.expedia.ca/lp/flights/601760/6233674/newark-to-ohio-river-valley) - [Flights from Buffalo to Quad Cities ](https://www.expedia.ca/lp/flights/602674/603001/buffalo-to-quad-cities) - [Flights from Buffalo to Ohio River Valley ](https://www.expedia.ca/lp/flights/602674/6233674/buffalo-to-ohio-river-valley) - [Flights from Birmingham to Ohio River Valley ](https://www.expedia.ca/lp/flights/602981/6233674/birmingham-to-ohio-river-valley) - [Flights from Quad Cities ](https://www.expedia.ca/lp/flights/603001/flights-from-quad-cities) - [Flights from Winnipeg to Quad Cities ](https://www.expedia.ca/lp/flights/6141041/603001/winnipeg-to-quad-cities) - [Flights from Ohio River Valley ](https://www.expedia.ca/lp/flights/6233674/flights-from-ohio-river-valley) - [Lake Michigan ](https://www.expedia.ca/Lake-Michigan-United-States-of-America.d6338716.Vacation-Attraction) - [Visit Ohio River Valley ](https://www.expedia.ca/Ohio-River-Valley.dx6233674) - [Quad Cities Vacations ](https://www.expedia.ca/Quad-Cities.d603001.Destination-Travel-Guides) - [Visit Quad Cities ](https://www.expedia.ca/Quad-Cities.dx603001) - [Visit Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa.dx6234151) - [Ace Rental Cars in Quad Cities ](https://www.expedia.ca/Ace-Car-Rentals-In-Quad-Cities.d603001-c2.Car-Rental-Guide-Suppliers) - [Advantage Rent-A-Car Rental Cars in Ohio River Valley ](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Ohio-River-Valley.d6233674-c3.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Quad Cities ](https://www.expedia.ca/Avis-Car-Rentals-In-Quad-Cities.d603001-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Quad Cities ](https://www.expedia.ca/Car-Rentals-In-Quad-Cities.d603001.Car-Rental-Guide) - [Pickup Car Rentals in Ohio River Valley ](https://www.expedia.ca/Pickup-Car-Rentals-In-Ohio-River-Valley.d6233674-tPickup.Car-Rental-Guide-Class) - [Thrifty Car Rental Rental Cars in Ohio River Valley ](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Ohio-River-Valley.d6233674-c45.Car-Rental-Guide-Suppliers) - [Things to do in Quad Cities ](https://www.expedia.ca/Things-To-Do-In-Quad-Cities.d603001.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app