Southeast Missouri
Travel Guide
Visit Southeast Missouri
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is CA $140 per night from Aug 23 to Aug 24
CA $140
CA $158 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is CA $82 per night from Aug 16 to Aug 17
CA $82
CA $89 total
Aug 16 - Aug 17
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
The Riverview
777 Main St Cape Girardeau MO
The price is CA $146 per night from Aug 18 to Aug 19
CA $146
CA $165 total
Aug 18 - Aug 19
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (89 reviews)
"Amazing stay. Clean, fun and peaceful. Would so go again."
Reviewed on Aug 1, 2026
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
Stay at this country house in Ste Genevieve. Enjoy laundry facilities. Popular attractions Crown Valley Winery and Hawn State Park are located nearby.
10/10 Exceptional! (154 reviews)
"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire ..."
Reviewed on Jul 5, 2026
Lake Wappapello
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
8.8/10 Excellent! (3 reviews)
"I had a reservation for 4 nights, also received a confermation and itinerary number from hotes.com, but upon arrival I found that hotels.cim never made the reservation with the place I was staying. The place i was supposed to stay at were as accommodating as they could be, tried to find me a place ..."
Reviewed on Jun 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southeast Missouri attractions
Things to do
Night Ghost Tour of Pythian Castle in Springfield Missouri
CA $28
per adult
96% of travellers recommend
Explore a world of travel with Expedia
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- Bluebird Meadows W/hot Tub and Pool Special
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- The Weber Farm
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- Home Sweet Home
- Cottages in Clearwater
- Hilton Hotels in Ste Genevieve
- Cabin Rentals in Centerville
- Pickleball Cafe & Micro Hotel
- Dexter Inn
- Quality Inn Perryville I
- Cheap Hotels in Bonne Terre
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- Rv Parks in Perryville
- Rv Parks in Chaffee
- Amazing lakeview Spring Lake Tree House #2 "LoveLight" w/ hot tub
- Hotels near Big River
- Lazy River Cabin on the edge of town only 1/2 mile from Current River !
- The Queen Bee Farm Stay/Hot tub
- Essex Hotels
- Pine Perfect Cabin on the edge of town only 1/2 mile from Current River!
- Secluded Private Cabin with Pool
- Silo Farm Haus
- Cheap Hotels in Viburnum
- Relax in the country at Countryside Villas!
- Secluded Cabin with Heated Pool
- Hilton Hotels in Perryville
- Cabin Rentals in Allenville
- Jackson Hotels
- Apartments in Ozora
- Bonne Terre Hotels
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- Urban Loft #4 BLACK · Urban Loft above BrewCo & Restaurant
- Triangle Inn Motel
- Condo Rentals in Fremont
- Cabin Rentals in Cadet
- Dexter Hotels
- Cabin Rentals in Leadwood
- Ozora Hotels
- Pet-Friendly Hotels in Jackson
- Fredericktown Hotels
- Cottages in Pocahontas
- Van Buren Hotels
- Alpaca Farm Stay
- Oyo Hickory House Inn
- Flights from Bonne Terre
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- Flights from St. Louis (STL) to Poplar Bluff (POF)
- Flights from Toronto (YTO) to Cape Girardeau (CGI)
- Flights from Chaffee
