Southeast Missouri

Travel Guide
Southeast Missouri

Where to stay in Southeast Missouri

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Kentucky Bend

Restaurants and shopping are just a few things travelers like about Kentucky Bend. A stop by Mississippi River is also recommended if you've got time to explore the area.

Kentucky Bend
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
The price is CA $90 per night from Jun. 3 to Jun. 4
CA $90
CA $102 total
includes taxes & fees
Jun 3 - Jun 4
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the ...
8.6/10 Excellent! (1,004 reviews)
"Always a wonderful for my wife and me at Auburn Place. We travel from Alabama to Kansas four times a year and always stay at Auburn Place. Great family atmosphere, wonderful staff, excellent breakfast, nice rooms—a great value."

Reviewed on May 24, 2024

Auburn Place Hotel And Suites
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
Fully refundable
The price is CA $97 per night from May 28 to May 29
CA $97
CA $102 total
includes taxes & fees
May 28 - May 29
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,008 reviews)
"Our third time staying here this year"

Reviewed on May 26, 2024

Motel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is CA $94 per night from Jun. 2 to Jun. 3
CA $94
CA $107 total
includes taxes & fees
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,003 reviews)
"Great value and super quiet."

Reviewed on May 23, 2024

Days Inn and Suites by Wyndham Sikeston
See all 570 properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.4/10 Exceptional! (126 reviews)
"When we walked in the lodge it was spotless. Very homey and clean. The staff was so kind. We will definitely be back."

Reviewed on May 10, 2024

Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Secluded Ozarks Tiny House cabin in Eminence, MO
Secluded Ozarks Tiny House cabin in Eminence, MO
Eminence
Stay at this cabin in Eminence. Enjoy a garden, patios, and cable/satellite TV service. Popular attractions Twin Rocks and Roy L. Beck Municipal Golf Course ...
9.8/10 Exceptional! (78 reviews)
Great place to stay
"My husband, young children (6 and 4), and I enjoyed our stay. The cabin was cute and clean. Great place to stay."

Reviewed on Mar. 6, 2024

Secluded Ozarks Tiny House cabin in Eminence, MO
RIVER FRONT HOUSE
RIVER FRONT HOUSE
Van Buren
Stay at this vacation home in Van Buren. Enjoy a garden, patios, and in-room fireplaces. Popular attractions Big Spring and Cave Spring Park are located ...
9.6/10 Exceptional! (24 reviews)
Beautiful View Along the Current
"My family group of five adults enjoyed our two nights here. The view and access to the Current was amazing. There are trees and vegetation between the house and river that allow for so many wonderful opportunities for bird watching right from the back screened in porch. We saw a bald eagle both mornings ..."

Reviewed on May 9, 2024

RIVER FRONT HOUSE
See all properties in Southeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

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Meramec Caverns

Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the coffeehouses.

Meramec Caverns
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Elephant Rocks State Park

Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.

Elephant Rocks State Park
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Ohio River

Commune with nature and explore the great outdoors at Ohio River during your travels in Valley Station. While you're in the area, wander around the parks.

Ohio River
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Reelfoot Lake

Commune with nature and explore the great outdoors at Reelfoot Lake during your travels in Tiptonville. Wander the lakeside and parks while you're in the area.

Reelfoot Lake
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Echo Bluff State Park

Explore the great outdoors at Echo Bluff State Park, a lovely green space in Salem. While you're in the area, stroll along the riverfront.

Echo Bluff State Park
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Montauk State Park

Explore the great outdoors at Montauk State Park, a lovely green space in Salem. Stroll along the riverfront or experience the area's museums.

Montauk State Park

Things to do

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Ozark Craft Beverage - Brewery Tour

CA $139
Per adult
Ozark Craft Beverage - Brewery Tour
See all activities in Southeast Missouri

Cities near Southeast Missouri

Photo by Summer Williams

Fredericktown

Photo by Alice Burghart

Bonne Terre

Photo by Jennifer Radman

Park Hills

Photo by Jordan Fratt

Van Buren