Panama Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Panama

Our top choices for Panama vacation rentals

Rio Verde by Villa Alejandro

Rio Verde by Villa Alejandro
2.5 star property
Los Naranjos
9.2 out of 10, Wonderful, (102 reviews)
"Loved the grounds and the hot tub room was awesome!"
United States
John
The price is CA $81
CA $118 total
includes taxes & fees
Apr 16 - Apr 17
Rio Verde by Villa Alejandro

La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (192 reviews)
"Staying and active in rural Boquete Panama is both a treat and a retreat of relaxation."
United States
Jerry
The price is CA $197
CA $219 total
includes taxes & fees
May 14 - May 15
La Isabela Suites

Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.0 out of 10, Very good, (86 reviews)
"The stay was wonderful. Highly recommend. Great value. "
Canada
Joseph
The price is CA $94
CA $295 total
includes taxes & fees
Apr 16 - Apr 17
Yoo Panamá by Boutique Apartments

Downtown Suites

Downtown Suites
3.0 star property
El Tropezón
9.0 out of 10, Wonderful, (105 reviews)
"Good location, nice rooms, great value."
United States
Robert
The price is CA $90
CA $99 total
includes taxes & fees
May 3 - May 4
Downtown Suites

El Cielo by Villa Alejandro

El Cielo by Villa Alejandro
3.5 star property
Boquete
9.4 out of 10, Exceptional, (108 reviews)
"Really beautiful property "
United States
Jason
The price is CA $88
CA $126 total
includes taxes & fees
May 13 - May 14
El Cielo by Villa Alejandro

Villa Alejandro

Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (145 reviews)
"Great location, great room and very responsive hotel."
United States
Tara
The price is CA $59
CA $94 total
includes taxes & fees
May 14 - May 15
Villa Alejandro

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (538 reviews)
"Very clean and amazing stay "
United States
Reinaldo
The price is CA $128
CA $140 total
includes taxes & fees
Apr 17 - Apr 18
Torres de Alba Hotel & Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (266 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is CA $165
CA $245 total
includes taxes & fees
Apr 16 - Apr 17
Arcadia Condo Suites

Casa Reina by Villa Alejandro

Casa Reina by Villa Alejandro
3.5 star property
Boquete
8.6 out of 10, Excellent, (19 reviews)
"Mountain views are beautiful, we enjoyed sitting on the deck and observing the mountains and wildlife. I got some really great sunrise pictures. "
United States
Paul
The price is CA $85
CA $120 total
includes taxes & fees
Apr 28 - Apr 29
Casa Reina by Villa Alejandro

Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (63 reviews)
"Good value and would recommend this place."
Australia
Yvon
The price is CA $38
CA $42 total
includes taxes & fees
May 3 - May 4
Surfari Bocas

Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (185 reviews)
"Best of the best, as always!"
United States
Rebecca
The price is CA $176
CA $193 total
includes taxes & fees
Apr 27 - Apr 28
Las Clementinas

Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
7.8 out of 10, Good, (279 reviews)
"Great location and good amenities for 1st time travellers Pool view is amazing... "
United States
nikita
The price is CA $56
CA $213 total
includes taxes & fees
May 7 - May 8
Boutique Apartments Panama

Villa Noelia

Villa Noelia
2.5 star property
Saboga
7.6 out of 10, Good, (28 reviews)
"There was new staff that were not up to the task for room keeping. We've contacted Cindy, the manager and she was responsive and made sure our stay was comfortable "
Canada
jerry
The price is CA $118
CA $173 total
includes taxes & fees
May 5 - May 6
Villa Noelia

Sanctuary by Playa Caracol Resorts

Sanctuary by Playa Caracol Resorts
Punta Chame
9.4 out of 10, Exceptional, (3 reviews)
"Amenities, clean comfortable room."
United States
Karryl
The price is CA $126
CA $200 total
includes taxes & fees
Apr 16 - Apr 17
Sanctuary by Playa Caracol Resorts

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is CA $86
CA $300 total
includes taxes & fees
Apr 30 - May 1
Living 73 Panamá by Boutique Apartments

Surfside Beachfront Suites by Playa Caracol Resorts

Surfside Beachfront Suites by Playa Caracol Resorts
3.5 star property
Punta Chame
7.6 out of 10, Good, (37 reviews)
"Love this trip your own private paradise we are definitely going again"
United States
Solomon
The price is CA $190
CA $270 total
includes taxes & fees
Apr 17 - Apr 18
Surfside Beachfront Suites by Playa Caracol Resorts

Aires frescos de Boquete

Aires frescos de Boquete
3.0 star property
Alto Boquete
9.0 out of 10, Wonderful, (4 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is CA $71
CA $78 total
includes taxes & fees
Apr 20 - Apr 21
Aires frescos de Boquete

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (184 reviews)
"Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! "
United States
Andrena
The price is CA $68
CA $268 total
includes taxes & fees
Apr 21 - Apr 22
Boutique Apartments Panamá Coco del Mar

Villas Residences by Playa Caracol Resorts

Villas Residences by Playa Caracol Resorts
3.5 star property
Punta Chame
8.4 out of 10, Very good, (5 reviews)
"The place was equipped, clean and amazing location, we truly enjoyed and will come back , thank you"
United States
Saro
The price is CA $160
CA $236 total
includes taxes & fees
Apr 16 - Apr 17
Villas Residences by Playa Caracol Resorts

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (88 reviews)
"The staff was absolutely phenomenal! So kind and accommodating even when certain events were out of their control they were still so wonderful!"
United States
Nicole
The price is CA $131
CA $185 total
includes taxes & fees
Apr 17 - Apr 18
Casco View Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews

Find out more about Panama

Everything you need to know about Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama vacation rentals we have selected for you start as low as CA $94 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panama rentals

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.