Title: Central San Diego Vacation Rentals from CA $153: Short-Term Rentals for 2026 | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central San Diego vacation rentals ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/06030fb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Room, 1 Queen Bed (East - Freeway Facing)](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Hillcrest 8.4/10 Very good (282 reviews) "The room was very small but very clean. Great place to stay for the short amount of time we needed it. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $136 CA $153 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/aa1995cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Middletown 9.6/10 Exceptional (113 reviews) "would definitely go back and stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kounwick [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/2000000/1550000/1548200/1548104/118c8f87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1550000/1548200/1548104/71e07597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1550000/1548200/1548104/c5e33f61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/2000000/1550000/1548200/1548104/26e196de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Andaz San Diego, by Hyatt [](https://www.expedia.ca/San-Diego-Hotels-Andaz-San-Diego-A-Concept-By-Hyatt.h1548104.Hotel-Information) Downtown San Diego 8.6/10 Excellent (1,001 reviews) "It was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele CA $228 CA $319 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/San-Diego-Hotels-Andaz-San-Diego-A-Concept-By-Hyatt.h1548104.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/01804477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/831e90be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/ae94e897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/b7ce7b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Country Estates [](https://www.expedia.ca/Ramona-Hotels-San-Diego-Country-Estates.h4694.Hotel-Information) San Diego Country Estates 9.4/10 Exceptional (251 reviews) "Had a very relaxing stay here... I would definitely come back and stay longer as i only stayed 2 days and didnt really explore the amenities. This was the quietest hotel i have stayed in so far! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lauren CA $79 CA $122 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Ramona-Hotels-San-Diego-Country-Estates.h4694.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/9a181764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/c76425ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (653 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KELLY CA $159 CA $224 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/834f95c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | In-room dining](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/3636bd40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/bc47b23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/4bb2e41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) Downtown San Diego 8.0/10 Very good (157 reviews) "Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $322 CA $367 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/176e7c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/37bf8b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/46a9ae00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/31020b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coronado Beach Resort [](https://www.expedia.ca/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) Historic Downtown Coronado 9.0/10 Wonderful (760 reviews) "Ideal location walkable to many restaurants and the beach. Great spot and lovely staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Justine CA $306 CA $337 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/f291ebe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/6177273a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/c50c50bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/02e6515e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wave Crest Resort [](https://www.expedia.ca/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information) Del Mar 9.2/10 Wonderful (147 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin CA $280 CA $362 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/0166b5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/850dc339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/bb1b86f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (5 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104960000/104953900/104953896/363be3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fireplace, Hot Tub, Patio & Bbq: San Diego Home [](https://www.expedia.ca/Spring-Valley-Hotels-Spacious-Spring-Valley-Home-W-Fenced-Yard-Grill.h104953896.Hotel-Information) Spring Valley CA $429 CA $893 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Spring-Valley-Hotels-Spacious-Spring-Valley-Home-W-Fenced-Yard-Grill.h104953896.Hotel-Information) ![Apartment](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/4b1c7130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/b9009bf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/b3d698d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/f66a43de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna [](https://www.expedia.ca/San-Diego-Hotels-NEW-Upscale-Downtown-San-Diego-Stay-Queen-Bed-Pool-Sauna.h118267698.Hotel-Information) Downtown San Diego CA $223 CA $542 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/San-Diego-Hotels-NEW-Upscale-Downtown-San-Diego-Stay-Queen-Bed-Pool-Sauna.h118267698.Hotel-Information) ![Family House, Private Bathroom | Living area](https://images.trvl-media.com/lodging/120000000/119310000/119307700/119307663/2ebdaf27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds, Non Smoking, Private Bathroom (No Hot Tub Access)](https://images.trvl-media.com/lodging/120000000/119310000/119307700/119307663/6bac412d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds, Non Smoking, Private Bathroom (No Hot Tub Access) | Living area](https://images.trvl-media.com/lodging/120000000/119310000/119307700/119307663/7be0e78b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119310000/119307700/119307663/04d9cfe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Cozy Studio 2 Queen Beds, Kitchen Walk to Water [](https://www.expedia.ca/San-Diego-Hotels-Beautiful-Home-With-Hottub-AC-NearBeach.h119307663.Hotel-Information) Point Loma 8.0/10 Very good (1 review) "The studio was beautiful, clean, and cozy. The only thing that I will say is that the pictures advertised show both the main home and the studio, so it is misleading as to what amenities are available in your own space. Other than that I enjoyed my stay and the owner was very prompt to respond to the few questions that I had." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fatimah CA $165 CA $416 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Diego-Hotels-Beautiful-Home-With-Hottub-AC-NearBeach.h119307663.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 1 Queen Bed with Sofa bed, Bay View | Living area](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/c58a022b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/9ea3f4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego [](https://www.expedia.ca/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Downtown San Diego 9.6/10 Exceptional (369 reviews) "My wife and I enjoyed our stay, the room was nice and very clean and this is a great location. The room is a few blocks from Little Italy and the Trolley's. We would stay here again if we travel to San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $242 CA $394 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/b28adcb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/e6859a38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/cc51c6db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/8ecd0448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View! [](https://www.expedia.ca/La-Jolla-Hotels-Walk-To-La-Jolla-Cove-Dtwn-Cottage-W-Ocean-View.h115485967.Hotel-Information) Village of La Jolla CA $826 CA $1,387 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/La-Jolla-Hotels-Walk-To-La-Jolla-Cove-Dtwn-Cottage-W-Ocean-View.h115485967.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-13&endDate=2026-02-14®ionId=6056570&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=APART_HOTEL) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=APARTMENT) Villas [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=CONDO) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=VACATION_HOME) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=COTTAGE) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=HOUSE_BOAT) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Central+San+Diego%2C+California%2C+United+States+of+America®ionId=6056570&latLong=32.824702%2C-117.136273&adults=2&startDate=2026-04-30&d1=2026-04-30&endDate=2026-05-03&d2=2026-05-03&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals) ## Top Central San Diego Hotel Reviews ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Great stay. Wonderful location " [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "it was nice and the staff were genuine and warm" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "Thanks " [](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "2 Thumbs up!!!" [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "great staff! very clean" [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "staff were friendly and accommodating." [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Frankly, I wasn't expecting much considering the low price. Boy, was I wrong. The room was small but comfortably furnished, and clearly recently renovated. The bed was deliciously firm, the bathroom was cleverly laid out, and everything was spotless. The only negative I can scrape together was the small number of hangers - three-in the small closet. I was able to park close to my room, and, perhaps best of all, the soundproofing was excellent. Only when people walked by talking loudly did I hear anything. The receptionist was welcoming and efficient, and set the tone for my entire stay. I will definitely return in the future." [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Staff" [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Stellar experience all around! Great service, incredible ambience, fantastic music, food, drinks, amenities, and fine touches that made our stay memorable and a new favorite on our list." [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ## Find out more about Central San Diego You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Central San Diego. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. 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