Title: Central San Diego Guest Houses from CA $144 | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring a pond, heritage architecture and a garden](https://images.trvl-media.com/place/507458/fd1dfc0c-838a-4496-9ef5-1b3047cae843.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Guest Houses in Central San Diego from CA $144 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-12&endDate=2025-12-14&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-12-26&endDate=2025-12-28&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-01-23&endDate=2026-01-25&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Central San Diego Guest Houses ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/158cade6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/6043b3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/075d2a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/08361f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central Mid-City 8.0/10 Very good (4) "Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya R. CA $119 CA $276 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d4d636ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/0d3d76b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/edab4306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/eb794f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden Cottage | 200Mbps | Sofabed | 55”TV | Patio University City 10/10 Exceptional (1) "Great place,near my son so was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) noel o. CA $172 CA $460 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/665db20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/c4b4e77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/1dcb5057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel Downtown Chula Vista 9.2/10 Wonderful (1001) "Well maintained and the staff are great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Junzky CA $131 CA $144 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/da8f2406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/f6cdb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/aea9aa0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed (Wedgewood) | Living area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6988f242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda Spring Valley 9.2/10 Wonderful (534) "Great room. Fun staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia CA $220 CA $238 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![TV, offices](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/e9768cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/cf0454ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/86755ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/w1194h673x3y0-99cf01e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Little Oasis Summ Country Club CA $114 CA $419 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/0fc89a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, wheelchair access](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/f64903ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/fb7f9bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/ddb692db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage On The Greens - Stunning Golf Course Views Rancho Bernardo 10/10 Exceptional (8) "It all went smoothly! The owners were very nice people, that made us feel welcome!A lovely location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard S. CA $191 CA $727 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/198e6a6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/505cfdc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/89729cf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books, streaming services](https://images.trvl-media.com/lodging/93000000/92450000/92449600/92449548/ab7e7ec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockaway North - Family Friendly, Garage Parking & Laundry Mission Beach 9.8/10 Exceptional (26) "It was the perfect little getaway for our family. The apartment apartment is small but very efficient and the property managers were awesome about their communication with us as we were checking in and getting stuff for our kids. We really appreciate it. The effort that the owners put into the space the bed was comfortable. The shower was awesome. Appliances and cookware new and ready to use. And best of all just steps from the beach as advertised. We would would happily return and hope that... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander C. CA $247 CA $562 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/San-Diego-Hotels-Rockaway-North-Family-Friendly.h92449548.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w902h683x61y0-c090cafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-eda5a9de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w905h683x59y0-0e1b8717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-3e9c584a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Encinitas - The Leucadia Beach Grotto - Pet-Friendly & Steps to Everything! Leucadia 10/10 Exceptional (14) "Great place and very accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas P. CA $232 CA $434 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/5afb3714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/6e926ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/3f8053a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91140000/91135200/91135120/a8221a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Newly Built Guest Home Mira Mesa 10/10 Exceptional (35) "Very modern place and convince to all the stores. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberta C. CA $457 CA $848 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/San-Diego-Hotels-Newly-Built-Guest-Home.h91135120.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-13®ionId=6056570&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AA_BF_PROMO_6056570) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation) ## Top Central San Diego Hotel Reviews ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "Clean room, nice staff, good breakfast, lose to airport and activities." [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Awesome " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Room was very clean. Great staff! " [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Good stay - very loud in certain rooms on the weekend " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Very kind " [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Our room was clean and comfortable. Love the little porch by the pool. Staff was very friendly. " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "The room was very clean and staff, specially, Eric was very accommodating, professional, and courteous. I would definitely stay again at this particular establishment Thank you!" [](https://expedia.ca/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "We stay for one night rooms a big double bed, great for. Short stay, staff was friendly. Wey affordable!" [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "Yes" [](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ## Find out more about Central San Diego ## Central San Diego Guest Houses information | Number of reviews | 1,559 | | --- | --- | | Accommodation | 19 Guest Houses | | Lowest Price | CA $144 | | Highest Price | CA $848 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Aparthotels in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apart-Hotels.d800122-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apartments.d800122-aaApartments.Travel-Guide-Accommodation) - [Condo Resorts in Beach Cities San Diego County](https://www.expedia.ca/Beach-Cities-San-Diego-County-Condominium-Resort.d800122-aaCondominiumResort.Travel-Guide-Accommodation) - 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