Title: Central San Diego Guest Houses from CA $160 | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Vacation Rentals in Central San Diego](https://expedia.ca/Central-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-03-27&endDate=2026-03-29&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2026-05-08&endDate=2026-05-10&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central San Diego guest houses ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/ce0e3d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, cookware/dishes/utensils, dining tables](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/e4a0797d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/33041dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/7b11689d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Loft Retreat - North Park SD [](https://www.expedia.ca/San-Diego-Hotels-Modern-Loft-Retreat-North-Park-SD.h120448291.Hotel-Information) North Park 10/10 Exceptional (1 review) "Yes!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cecil CA $164 CA $458 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Loft-Retreat-North-Park-SD.h120448291.Hotel-Information) ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/a632fc97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/43d03b41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/6fa779d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/e8b8e879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) Mid-City 8.4/10 Very good (5 reviews) "Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya R. CA $126 CA $281 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/7bcce1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/15c22d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/fbf11521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/19928405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Spacious Full Bed Studio [](https://www.expedia.ca/San-Diego-Hotels-Private-Spacious-Full-Bed-Studio.h121920680.Hotel-Information) Mid-City CA $99 CA $440 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/San-Diego-Hotels-Private-Spacious-Full-Bed-Studio.h121920680.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d4d636ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/155aa17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/0d3d76b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/eb794f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded Garden Cottage Walk to Shops + 55” TV [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) University City 10/10 Exceptional (1 review) "Great place,near my son so was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) noel o. CA $200 CA $497 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/81c1006b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40d9e6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/a2b981e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) Downtown Chula Vista 9.2/10 Wonderful (1,001 reviews) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $145 CA $160 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/fa4065fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/d6f22806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed (Wedgewood) | Living area](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/6988f242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/a4d923ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) Jamul 9.2/10 Wonderful (549 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christophe CA $225 CA $244 total includes taxes & fees Mar 17 - Mar 18 [](https://www.expedia.ca/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/0fc89a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/ab9fbd6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/ba454874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99230000/99223400/99223393/fb7f9bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cottage On The Greens - Stunning Golf Course Views [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) Rancho Bernardo 10/10 Exceptional (9 reviews) "It all went smoothly! The owners were very nice people, that made us feel welcome!A lovely location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard S. CA $185 CA $703 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/San-Diego-Hotels-Cottage-On-The-Greens-Studio.h99223393.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w874h683x75y0-fc4520ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w4000h2662x0y0-eda5a9de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/9bccd2a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/96000000/95360000/95356000/95355923/w905h683x59y0-0e1b8717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Encinitas - The Leucadia Beach Grotto - Pet-Friendly & Steps to Everything! [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) Leucadia 10/10 Exceptional (18 reviews) "Great spot, great property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MIchael L. CA $237 CA $436 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Encinitas-Hotels-Few-Blocks-From-The-Beach-Restaurants-Steps-Away-From-Private-Poolside.h95355923.Hotel-Information) ![TV, offices](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/e9768cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/cf0454ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/aca5b4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113910000/113902300/113902265/86755ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Little Oasis Summ [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) Country Club CA $130 CA $431 total includes taxes & fees Mar 19 - Mar 20 [](https://www.expedia.ca/Escondido-Hotels-The-Little-Oasis-Summ.h113902265.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24®ionId=6056570&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_6056570) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Guest-Houses.d6056570-aaGuestHouses.Travel-Guide-Accommodation) ## Top Central San Diego Hotel Reviews ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Rooms were modern and comfy. Nice pool area. Lounge with coffee in the morning. Helpful staff. Good location. " [](https://expedia.ca/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb_y.jpg) ### Legacy Resort Hotel & Spa 8/10 Good "Im" [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/2d829d4d_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Great location and near many places to easy and shop" [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area](https://images.trvl-media.com/lodging/1000000/100000/97900/97876/ab8ed617_y.jpg) ### Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area 8/10 Good "Very clean, spacious room , and staff was polite. I recommend this property. " [](https://expedia.ca/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Hotel-CircleSeaWorld-Area.h97876.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 2/10 Terrible "Satisfied with the stay and everything was clean." [](https://expedia.ca/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/027b3bfa_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 8/10 Good "The property was clean and comfortable, though it could use some minor maintenance like touch-up paint. It’s a bit outdated, but overall still a pleasant place to stay. Parking is expensive. I would stay here again." [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "I literally had the best room in the place and will request this room next time if possible!" [](https://expedia.ca/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/ce2dc6d1_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Love this place. Everything was there! A bar for drinking, a pool for lounging, a diner for eating, and a restaurant for more eating. The place was one of a kind, and we plan on coming back." [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/bf074aa5_y.jpg) ### Kings Inn San Diego 2/10 Terrible "Staff was uncooperative with refunding a reservation that couldn't be completed because of a hospitalization. " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ## Find out more about Central San Diego ## Central San Diego Guest Houses information | Number of reviews | 1,584 | | ----------------- | --------------- | | Accommodation | 19 Guest Houses | | Lowest Price | CA $160 | | Highest Price | CA $703 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - More ways to book - [Aparthotels in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apart-Hotels.d800122-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Apartments.d800122-aaApartments.Travel-Guide-Accommodation) - [Condo Resorts in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Condominium-Resort.d800122-aaCondominiumResort.Travel-Guide-Accommodation) - [Inns in Beach Cities San Diego County ](https://www.expedia.ca/Beach-Cities-San-Diego-County-Inns.d800122-aaInns.Travel-Guide-Accommodation) - 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