Title: Byron Vacation Packages & Trips 2026 from CA $679 | Expedia.ca [Hotels in Byron](https://expedia.ca/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels)[Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Byron Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Byron Vacation Book a tailored Byron vacation package that includes only the things you need and nothing you don't. Good for bars and pubs, history and culture, think about staying in the neighborhood of Downtown Rochester. There's plenty to put on your must-do list during your trip to Byron, starting with leading attractions such as [Oxbow Park](https://www.expedia.ca/Oxbow-Park-Byron.d6308341.Vacation-Attraction) and [Douglas Trail](https://www.expedia.ca/Douglas-Trail-Rochester.d553248621532649599.Vacation-Attraction). A couple of quick clicks is all it takes to put together the ultimate Byron vacation on Expedia. ## Top Byron Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Aspen Select](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Aspen Select Kutzky Park CA $679 per person May 29 - Jun 2 found 1 day ago Roundtrip non-stop flight included Syracuse (SYR) to Rochester (RST) 8.4/10 Very Good! (1,000 reviews) Room was very clean. Decent continental breakfast. Excellent service Reviewed on Apr 1, 2026 ![The Towers At Kahler Grand Hotel](https://images.trvl-media.com/lodging/17000000/16120000/16119600/16119557/978fdbcd_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Towers At Kahler Grand Hotel Downtown Rochester CA $1,412 per person May 29 - Jun 2 found 1 day ago Roundtrip non-stop flight included Syracuse (SYR) to Rochester (RST) 9.4/10 Exceptional! (97 reviews) Excellent accommodations, amazing staff Reviewed on Dec 24, 2025 ![The Berkman](https://images.trvl-media.com/lodging/47000000/46300000/46291500/46291477/5776b64a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Berkman Folwell CA $958 per person May 29 - Jun 2 found 1 day ago Roundtrip non-stop flight included Syracuse (SYR) to Rochester (RST) 9.6/10 Exceptional! (388 reviews) This hotel is great for families that need to stay close to St Mary's or Mayo clinics. The rooms were comfy and pantry was priced decently for any last minute needs. It was very clean, easy to acces, amd walking distance to great restaurants. Reviewed on Mar 24, 2026 ![Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys](https://images.trvl-media.com/lodging/10000000/9130000/9120100/9120037/674459db_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys Kutzky Park CA $764 per person May 29 - Jun 2 found 1 day ago Roundtrip non-stop flight included Syracuse (SYR) to Rochester (RST) 9.2/10 Wonderful! (499 reviews) Friendly staff, quiet spacious room and convenient location. Reviewed on Mar 10, 2026 ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Kahler Inn and Suites - Mayo Clinic Area Downtown Rochester CA $838 per person May 29 - Jun 2 found 1 day ago Roundtrip non-stop flight included Syracuse (SYR) to Rochester (RST) 8/10 Very Good! (1,550 reviews) We chose to stay here because of the availability of parking, the easy subway access to Mayo and because of the Caribou Coffee store off the lobby. Also very appreciative that they brought back the included breakfast. Reviewed on Apr 2, 2026 ## Ready to book your vacation to Byron? Choose your dates ## Byron Hotel Deals ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Kahler Grand Hotel 20 2nd Ave Sw Rochester MN Fully refundableReserve now, pay when you stay CA $187 CA $215 total Apr 10 - Apr 11 includes taxes & fees 8.4/10 Very Good! (1,982 reviews) Room was nice and big. Convenient to everything downtown. Reviewed on Apr 5, 2026 [](https://expedia.ca/Hotel-Search?startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&selected=25516&PinnedHotelID=25516&HadPinnedHotel=true®ionId=553248623858895563) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Kahler Inn and Suites - Mayo Clinic Area 9 3rd Ave Nw Rochester MN Fully refundableReserve now, pay when you stay CA $195 CA $224 total Apr 7 - Apr 8 includes taxes & fees 8/10 Very Good! (1,548 reviews) The keys would stop working frequently. This caused us not to get in our room and frequent visits to the front desk. The pool area is very small and the gym had water standing in the floor. Reviewed on Apr 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=07%2F04%2F2026&endDate=08%2F04%2F2026&selected=171566&PinnedHotelID=171566&HadPinnedHotel=true®ionId=553248623858895563) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 220 S Broadway Rochester MN Fully refundable CA $151 CA $173 total May 3 - May 4 includes taxes & fees [](https://expedia.ca/Hotel-Search?startDate=03%2F05%2F2026&endDate=04%2F05%2F2026&selected=5327&PinnedHotelID=5327&HadPinnedHotel=true®ionId=553248623858895563) [See all 393 properties in Byron](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=06%2F04%2F2026&endDate=07%2F04%2F2026®ionId=553248623858895563) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app