Title: Top 10 Hotels Near 22nd Street Station from CA $109 | Expedia.ca [Potrero Hill Travel Guide](https://expedia.ca/San-Francisco-Potrero-Hill.dx506137)[Potrero Hill Car Rentals](https://expedia.ca/Car-Rentals-In-Potrero-Hill.d506137.Car-Rental-Guide)[Potrero Hill Vacation Packages](https://expedia.ca/Potrero-Hill.d506137.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 9 - Feb 10](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-09&endDate=2026-02-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 10 - Feb 11](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for 22nd Street Station hotels ![Tapas bar](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/58dd339c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/44e1b72d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/26f4395c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LUMA Hotel San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) 1.9 km from 22nd Street Station 9.6/10 Exceptional (2,458 reviews) "Overall a great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $272 CA $320 total includes taxes & fees Feb 20 - Feb 21 [](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/91986f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/6a4e602e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/b089b5be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 16 per person)](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/f9d4387a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place San Francisco Downtown [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) 2.3 km from 22nd Street Station 9.4/10 Exceptional (1,989 reviews) "Check-in and check-out went smoothly with staff, clean rooms and overall nice hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Giovanna CA $245 CA $288 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/004f15cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Park View](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/3c515aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e4464a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e96af726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel VIA [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) 2.4 km from 22nd Street Station 9.2/10 Wonderful (1,514 reviews) "Great front desk staff , and great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcus CA $245 CA $288 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/d4275eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Queen Bed (Sheila's Chapeau)](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/6a7cfb2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/439430c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/791b3727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Noe's Nest Bed and Breakfast [](https://www.expedia.ca/San-Francisco-Hotels-Noes-Nest-Bed-And-Breakfast.h11462191.Hotel-Information) 2.7 km from 22nd Street Station 9.4/10 Exceptional (123 reviews) "A very nice and comfortable B&B place to stay..... nestled in the Noe Valley section of San Francisco" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lester CA $321 CA $374 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/San-Francisco-Hotels-Noes-Nest-Bed-And-Breakfast.h11462191.Hotel-Information) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/da85ef17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/f7c5f6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5517eff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental San Francisco by IHG [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) South of Market, 2.9 km from 22nd Street Station 9.2/10 Wonderful (1,089 reviews) "Very nice hotel, great amenities and excelente service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $257 CA $359 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/abad6cd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/04a59767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/5931a034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/5335e149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canopy by Hilton San Francisco SoMa [](https://www.expedia.ca/San-Francisco-Hotels-Canopy-By-Hilton-San-Francisco-SoMa.h27110513.Hotel-Information) South Park, 2.9 km from 22nd Street Station 9.0/10 Wonderful (1,007 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raquel CA $262 CA $309 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/San-Francisco-Hotels-Canopy-By-Hilton-San-Francisco-SoMa.h27110513.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/febae001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/b1b7eea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/80647523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/00836df3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fiona [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Fiona.h96810663.Hotel-Information) South of Market, 2.8 km from 22nd Street Station 8.6/10 Excellent (1,015 reviews) "Nice size room , comfy bed and nice staff and hotel convenient parking " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shawna CA $110 CA $156 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Fiona.h96810663.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/100ffc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/e282d47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/1656ff5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) South Park, 3.2 km from 22nd Street Station 9.2/10 Wonderful (1,002 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $231 CA $329 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/7fe7eb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/398a6ca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse, 1 Bedroom, City View | Living room](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/3afd96af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/f11ecdc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) South Park, 3.2 km from 22nd Street Station 9.0/10 Wonderful (1,004 reviews) "This hotel exceeded all expectations in every way. The accommodations, service, and atmosphere were exceptional. I truly enjoyed my stay and would not hesitate to return." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andres CA $228 CA $317 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7240000/7237700/7237605/f5b61fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/8000000/7240000/7237700/7237605/fa3ed2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 Double Bed, Private Bathroom](https://images.trvl-media.com/lodging/8000000/7240000/7237700/7237605/2b87e95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry](https://images.trvl-media.com/lodging/8000000/7240000/7237700/7237605/aaee144f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Winsor Hotel [](https://www.expedia.ca/San-Francisco-Hotels-Winsor-Hotel.h7237605.Hotel-Information) 3.1 km from 22nd Street Station 9.6/10 Exceptional (4 reviews) "Good location in downtown, but neighborhood a little scary. Clean room, covers all basic needs. Helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandru CA $93 CA $109 total includes taxes & fees Feb 28 - Mar 1 [](https://www.expedia.ca/San-Francisco-Hotels-Winsor-Hotel.h7237605.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-23&endDate=2026-02-24®ionId=6173593&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to 22nd Street Station | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Tapas bar](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/58dd339c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)LUMA Hotel San Francisco | 4.0 star property | 9.6Exceptional2,458 reviews | View | | | | | | | ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/91986f78.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hyatt Place San Francisco Downtown | 3.0 star property | 9.4Exceptional1,989 reviews | View | | | | | | | ![Property entrance](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/004f15cd.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel VIA | 4.0 star property | 9.2Wonderful1,514 reviews | View | | | | | | | ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/d4275eec.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Noe's Nest Bed and Breakfast | 3.5 star property | 9.4Exceptional123 reviews | View | | | | | | | ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)InterContinental San Francisco by IHG | 4.0 star property | 9.2Wonderful1,089 reviews | View | | | | | | ## Top 22nd Street Station Hotel Reviews ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Spacious rooms and the pool is special. Excellent location in the city. I would recommend and stay again. Feels very safe." [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Hotel Caza Fisherman's Wharf](https://images.trvl-media.com/lodging/39000000/38250000/38249400/38249309/575b2d5c_y.jpg) ### Hotel Caza Fisherman's Wharf 10/10 Excellent "The staff makes u feel like family and u matter" [](https://expedia.ca/San-Francisco-Hotels-Hotel-Caza.h38249309.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "The room was clean. Bed was comfortable. Staff were friendly. Check in was speedy. The best part was the breakfast buffet. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Room was clean and staff was nice! They answered all questions I had and were really helpful overall! " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![LUMA Hotel San Francisco ](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9_y.jpg) ### LUMA Hotel San Francisco 10/10 Excellent "Great hotel when staying in San Francisco near the ball park." [](https://expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Comfort Inn by the Bay](https://images.trvl-media.com/lodging/1000000/10000/6000/5984/d439a184_y.jpg) ### Comfort Inn by the Bay 10/10 Excellent "Excellent Guest Service" [](https://expedia.ca/San-Francisco-Hotels-Comfort-Inn-By-The-Bay.h5984.Hotel-Information) ![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "Clean room. Nice staff!" [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Clean room " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Great location " [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ## Frequently asked questions ### What's the area like around 22nd Street Station? ### What's the best place to stay close to 22nd Street Station? ### How many hotels will I find near 22nd Street Station? ### What can I see and do near 22nd Street Station? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - 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