Title: Book The Best Hotels in Seneca, SC for 2025 from CA $92 - Competitive Prices - Expedia.ca [Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Seneca, SC from CA $92 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Seneca Cabin [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=CABIN) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=HOT_TUB) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&travelerType=family_friendly) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=COTTAGE) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=APARTMENT) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&amenities=WATER_PARK) Condo [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2025-11-13&d1=2025-11-13&endDate=2025-11-15&d2=2025-11-15&lodging=CONDO) ## Check prices for these dates Tonight [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 1,628 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/01158bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson Seneca 9.0/10 Wonderful (1006) "Very beautiful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $152 CA $189 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Cabin, 1 Queen Bed](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/361e76b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f5941a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/ec2a8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy Seneca 9.8/10 Exceptional (44) "The place was absolutely magnificent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $180 CA $259 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/dac98c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area Seneca 6.8/10 (710) "The rooms have been renovated it was nice and clean especially for the price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherri CA $103 CA $113 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/347fe1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/270-2efd6ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 Downtown 8.0/10 Very good (651) "Friendly check in, clean room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) connie CA $112 CA $131 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/ac7a917f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Hearing, Roll-In Shower)](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/d36e662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson Seneca 9.2/10 Wonderful (778) "Clean room, staff was great, will always stay at this hotel in Clemson. Best place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gretchen CA $148 CA $162 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (199) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $167 CA $184 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/ce65516b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/877edfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Seneca-Clemson Area Seneca 9.4/10 Exceptional (648) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $191 CA $210 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/83901eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (625) "Convenient for Clemson visits." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $119 CA $130 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/e75c3696.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/3e9b7ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/3f227a0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/937af897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Anderson North I-85 Anderson 7.6/10 Good (43) "Great service and very helpful employees" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Braden CA $110 CA $122 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Woodspring-Suites-Anderson-North-I-85.h114348655.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-050d425f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center Clemson 8.2/10 Very good (1002) " Clean room, breakfast, staff very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Claudia CA $117 CA $130 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/f179f4b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area Clemson 8.2/10 Very good (1001) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $130 CA $145 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/7cb8ae6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/f49d90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/441edd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson Anderson 7.6/10 Good (1038) "Rooms were clean, the property was well kept, complimentary breakfast and location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayla CA $88 CA $97 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/389cca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0c8d8851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/64115ebf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG Anderson 9.0/10 Wonderful (574) "Good breakfast, clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $144 CA $159 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/ca1bd62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/2d87513f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/acae25f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Easley/Greenville Easley 7.4/10 Good (722) " Room was clean and comfortable. Bed slept well. Desk clerk (Cassidy?) at check-in was very friendly and helpful. On the road early so did not have the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $94 CA $104 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/1c4bc101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/78008f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/10c576cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson Clemson 8.0/10 Very good (1013) "Very nice staff and great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberley CA $409 CA $455 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/bb1bfaf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/dfa7a980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Anderson Anderson 9.0/10 Wonderful (657) "When I got there to check in the front desk worker was very nice and helpful room was nice and clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $153 CA $170 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/b60fead8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/13ba386f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/813e9213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/3a6df04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Anderson Clemson Anderson 7.0/10 Good (827) "Clean room | Staff | Parking | Family-friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vladimir CA $83 CA $92 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/14e3230b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson Anderson 8.2/10 Very good (1001) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lee CA $111 CA $124 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Superior Room, 2 Queen Beds](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/ee0e0eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson Clemson 9.8/10 Exceptional (718) "Very nice hotel, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin CA $250 CA $277 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/05d8cd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/199642a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn Clemson 9.6/10 Exceptional (950) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mindi CA $208 CA $231 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14®ionId=6548&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Hotels.d6548.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Hotels.d6548.Travel-Guide-Hotels) ## Where to stay in Seneca Seneca, South Carolina, is a delightful destination for outdoor enthusiasts and romantics alike. Discover the scenic beauty of the nearby Clemson area, perfect for family-friendly activities and lakeside camping. Enjoy the friendly atmosphere and sunny weather while exploring Oconee County's charming spots. Don't miss the vibrant art scene and budget-friendly experiences that await you in this lovely region. Seneca promises a memorable vacation filled with adventure and relaxation. - Pine Ridge Point - Downtown - Indian Oaks - Serenity Bay - Keowee Plantation [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976472456) ![Pine Ridge Point map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BalsEhndyNwOsU%7BHgHcDeNnS%7BErOdYfAfUsFnD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=XLaSweFr5Wdz_LaNTr-TqlSNujY=) ### Pine Ridge Point Pine Ridge Point, nestled in Seneca, South Carolina, offers a charming escape for travellers seeking outdoor adventures and stunning scenery. While visitor numbers peak from July to August and in October, the area remains inviting year-round. Indulge in romantic getaways by the beautiful Lake Keowee and Lake Jocassee, or immerse yourself in culture at the historic Clemson University. Whether you're looking for relaxation or exploration, Pine Ridge Point promises a memorable vacation experience surrounded by nature's beauty. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976472456) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=944725335916802048) ![Downtown map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:uctrE%7CnjyNkAmSco%40tHaFFw%40sG%7DDq%7E%40rhAaLzEbgADdTmNlA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=W0Bl9iLKssG7Dfgw2px-gKD4lJc=) ### Downtown Downtown Seneca, South Carolina, offers a charming blend of culture and nature, making it an ideal vacation spot. Visitors can explore the historic Clemson University, perfect for a cultural getaway, or enjoy the romantic scenery at Lake Keowee, ideal for outdoor enthusiasts. For sports fans, Memorial Stadium provides a glimpse into the region's vibrant sporting culture. While visitor numbers peak in the summer and fall, Downtown's attractions promise a delightful experience year-round, whether you're seeking adventure or relaxation. [See properties](https://www.expedia.ca/Hotel-Search?regionId=944725335916802048) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976482027) ![Indian Oaks map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BxzrEj%7CnyNyH%7DNhDyY%60RgU%7EJNrClNmGdXwUzV&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=PEwl89Df4b_h_205oaRH2JFAjNI=) ### Indian Oaks Nestled in Seneca, South Carolina, Indian Oaks is a charming neighborhood that offers a blend of scenic beauty and outdoor adventures. With peak visitor numbers in July, August, and October, it attracts those seeking romance and picturesque landscapes. Nearby, you'll find Clemson University, a historic hub for cultural exploration, and Lake Keowee, perfect for a relaxing beach day or romantic outing. Don't miss the iconic Memorial Stadium, a must-visit for sports enthusiasts. Whether you're looking for a serene getaway or an active vacation, Indian Oaks has something special to offer every traveller. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976482027) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976468572) ![Serenity Bay map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:gzfsEj%7BmyNoOuOmDuXn%5EwOWpa%40yGpW&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=8pP_LE48Ao4j6S-mrEGIMKeSvt4=) ### Serenity Bay Serenity Bay, nestled in the picturesque Saxony Forest, South Carolina, is a hidden gem for travellers seeking a blend of romance and outdoor adventure. With its scenic beauty and tranquil atmosphere, it's ideal for leisurely summer getaways, especially from July to August and in October. Explore the charming Lake Keowee for a serene aquatic experience or immerse yourself in the rich history at Clemson University and Memorial Stadium. Whether you're in search of breathtaking views or cultural insights, Serenity Bay promises a memorable escape. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976468572) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976477960) ![Keowee Plantation map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ogyrEtunyN%7BPsc%40fG%7BRjU_CxQpf%40q%5E%7CS&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=peRRMoUk5Yoxpsa1fhNr53skzwc=) ### Keowee Plantation Keowee Plantation in Seneca, South Carolina, is a picturesque neighbourhood that offers a delightful mix of outdoor experiences and stunning scenery. Peak tourist season runs from July to August and again in October, making it an ideal time for romance and relaxation. Explore nearby attractions like historic Clemson University, the serene Lake Keowee perfect for beach outings, and the iconic Memorial Stadium for sports culture. With its natural beauty and cultural highlights, Keowee Plantation is a charming destination for any Canadian traveller looking to unwind and immerse themselves in Southern hospitality. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976477960) ## Learn more about Seneca Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons. [See all hotels in Seneca](https://www.expedia.ca/Hotel-Search?startDate=2025-11-13&endDate=2025-11-14&adults=2®ionId=6548) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=899&h=314&p=1&q=high) ## More cheap stays in Seneca ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Anderson 1007 George Smith Mill Rd, Anderson, SC CA $88 CA $97 total Nov 2 - Nov 3 includes taxes & fees 7.6/10 Good! (1,035 reviews) [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Clemson Hotel & Conference Center 1310 Tiger Blvd, Clemson, SC CA $117 CA $130 total Nov 2 - Nov 3 includes taxes & fees 8.2/10 Very Good! (1,003 reviews) [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lakeside Lodge Clemson 13500 Clemson Blvd, Seneca, SC CA $152 CA $189 total Nov 2 - Nov 3 includes taxes & fees 9/10 Wonderful! (1,005 reviews) [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Comfort Inn & Suites Clemson - University Area](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Clemson - University Area 1305 Tiger Blvd, Clemson, SC CA $130 CA $145 total Nov 23 - Nov 24 includes taxes & fees 8.2/10 Very Good! (1,011 reviews) [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Horizon Inn & Suites](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/1611bef6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Horizon Inn & Suites 3025 N Main Street, Anderson, SC CA $81 CA $94 total Nov 9 - Nov 10 includes taxes & fees 4.6/10 (218 reviews) [](https://expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Inn @ Clemson 1303 Tiger Blvd, Clemson, SC CA $409 CA $455 total Oct 31 - Nov 1 includes taxes & fees 8/10 Very Good! (1,008 reviews) [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ## Hotels in Seneca with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_w.jpg) 4 Star Hotels 8 properties [](https://expedia.ca/4Star-Seneca-Hotels.s40-0-d6548.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715_w.jpg) 3 Star Hotels 188 properties [](https://expedia.ca/3Star-Seneca-Hotels.s30-0-d6548.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_w.jpg) 2 Star Hotels 133 properties [](https://expedia.ca/2Star-Seneca-Hotels.s20-0-d6548.Travel-Guide-Filter-Hotels) ## Find out more about Seneca ### Top reasons to visit Seneca - **Outdoor Adventures:** Seneca offers stunning landscapes for hiking, golfing, and lakeside camping, perfect for nature lovers. - **Charming Parks:** Explore urban parks and picnic spots that provide a serene escape for families and couples. - **Vibrant Art Scene:** Discover local art and cultural experiences that showcase Seneca's creative community. - **Historic Colleges:** Visit nearby historic institutions that add cultural depth to your trip. - **Affordable Accommodations:** Enjoy a range of comfortable hotels catering to various budgets and needs. ### Find great hotels in Seneca Discover a variety of accommodation options in Seneca, South Carolina, where comfort meets affordability. With hotels ranging from 2 to 4 stars, you'll find the perfect place to unwind, whether you're travelling for business or leisure. Enjoy family-friendly amenities, pet-friendly services, and a welcoming atmosphere that caters to every type of traveller. Experience the best of Seneca with a selection of hotels designed to enhance your stay. - **[Best Western Plus Clemson Hotel & Conference Center:](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)** Located a short drive from Seneca, the Best Western Plus Clemson Hotel & Conference Center offers a welcoming environment tailored for both business and pet-friendly travellers. This hotel features comprehensive business amenities including multiple meeting rooms, a 24-hour business centre, and a spacious conference centre, making it ideal for corporate events. The property also accommodates pets, allowing you to bring your furry friends along, with policies in place to ensure a comfortable stay for all. Guests appreciate the quality of service, modern rooms, and the convenience of being close to local attractions. - **[Comfort Inn & Suites Clemson - University Area:](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information)** Situated conveniently 11.3km from Seneca, the Comfort Inn & Suites Clemson - University Area is perfect for those seeking a blend of business and leisure. This hotel boasts excellent facilities for business travellers, including a 24-hour business centre and meeting rooms. It is also pet-friendly, permitting dogs and cats, ensuring that you can travel without leaving your pets behind. Guests enjoy the warm hospitality, comfortable accommodations, and a complimentary breakfast that fuels your day of exploring or working. - **[Inn @ Clemson:](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information)** The Inn @ Clemson is an ideal choice for those focused on business travel, located 11.3km from Seneca. This hotel prioritizes the needs of business guests with its well-equipped business centre and multiple meeting rooms for gatherings or conferences. While it may not be specifically pet-friendly, its professional atmosphere and commitment to service make it a top choice for corporate stays. Visitors often highlight the clean facilities, attentive staff, and convenient location close to the university and local amenities, ensuring a productive and pleasant experience. ### Things to do in Seneca Seneca, South Carolina, is ideal for outdoor enthusiasts and couples seeking a scenic getaway. Enjoy the picturesque landscapes while engaging in activities such as golfing and exploring recreational areas. For a fun twist, try your hand at an escape room or relax in one of the lovely picnic spots. Whether you’re looking for adventure or romance, Seneca offers a delightful mix of experiences to make your vacation memorable. **Shopping** In Seneca, you can shop at Wyndham Plaza and Applewood Shopping Center, both offering a variety of family and city vibes. If you're up for a drive, visit Anderson Mall, located 30.6km away, where you'll find a wider selection of stores and entertainment options. **Recreation** [Littlejohn Coliseum](https://www.expedia.ca/Littlejohn-Coliseum-Hotels.0-l6228662-0.Travel-Guide-Filter-Hotels) offers an energetic atmosphere for sports enthusiasts, while [Walker Golf Course](https://www.expedia.ca/Walker-Golf-Course-Hotels.0-l6228657-0.Travel-Guide-Filter-Hotels) provides a refreshing outdoor experience amidst beautiful landscapes. For a more tranquil setting, [Keowee Key Golf Course](https://www.expedia.ca/Keowee-Key-Golf-Course-Hotels.0-l6228693-0.Travel-Guide-Filter-Hotels) invites you to enjoy scenic views and a relaxing day on the greens, all within a short drive from Seneca. **Adventure** Experience thrilling water sports at [Ultimate Action Sports](https://www.expedia.ca/Ultimate-Action-Sports-Hotels.0-l553248621532656707-0.Travel-Guide-Filter-Hotels), located 25.7km from Seneca, where you can enjoy the excitement of various aquatic activities. For breathtaking views and a refreshing hike, explore the scenic [Bartram Trail](https://www.expedia.ca/Bartram-Trail-Hotels.0-l553248621532656642-0.Travel-Guide-Filter-Hotels), situated 38.6km away, or venture onto the [Shortline Trailhead](https://www.expedia.ca/Shortline-Trailhead-Hotels.0-l553248621561884155-0.Travel-Guide-Filter-Hotels), 41.8km away, for more outdoor fun. **Nightlife** Experience vibrant nightlife at [Foothills Playhouse](https://www.expedia.ca/Foothills-Playhouse-Hotels.0-l553248621561867899-0.Travel-Guide-Filter-Hotels), only 35.4km from Seneca, showcasing captivating performances. For more theatrical charm, visit [Highlands Playhouse](https://www.expedia.ca/Highlands-Playhouse-Hotels.0-l553248621532656653-0.Travel-Guide-Filter-Hotels), 46.7km away. In Seneca itself, The Gauntlet offers a delightful mix of culture and entertainment, perfect for a family night out. ### Booking tips and Expedia advantages for Seneca To save money during your visit to Seneca, South Carolina, consider exploring free attractions like Clemson University, Tri-County Technical College, and Larry W. Abernathy Waterfront Park. For transportation, renting a bicycle or using a car can be cost-effective. Plan your trip between December and February for the lowest accommodation rates, with Tuesdays being the cheapest nights to stay. Use Expedia to compare hotel deals, filter by price, and consider bundling your hotel with flights and activities for additional savings. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Seneca are December to February, where the prices are slightly lower. This is in comparison to September to November, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Seneca is Tuesday. The most expensive day to stay in Seneca is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred hotel type. To find the best prices and deals, simply sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save some money by combining your hotel stay in Seneca with your flights and activities through an Expedia package. ### Find the best attractions in Seneca Seneca, South Carolina, offers a delightful blend of outdoor adventures and romantic scenery, perfect for a getaway. Visitors can explore urban parks, historic colleges, and serene lakes, making it ideal for families and culture enthusiasts alike. Whether you're looking for a leisurely stroll or an immersive cultural experience, Seneca's attractions cater to a variety of interests, ensuring a memorable vacation for everyone. - **[Clemson University:](https://www.expedia.ca/Clemson-University-Hotels.0-l6127431-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the vibrant culture of Clemson University, a historic institution located 11.3km from Seneca. Explore its beautiful campus, rich history, and engaging atmosphere that fosters creativity and learning. - **[Lake Keowee:](https://www.expedia.ca/Lake-Keowee-Hotels.0-l553248635056398567-0.Travel-Guide-Filter-Hotels)** Experience the romance and stunning scenery at Lake Keowee, situated 14.5km away. Enjoy outdoor activities like swimming, boating, and picnicking along its picturesque beaches, perfect for a relaxing day with loved ones. - **[Memorial Stadium:](https://www.expedia.ca/Memorial-Stadium-Hotels.0-l6193935-0.Travel-Guide-Filter-Hotels)** Visit the historic Memorial Stadium, located 9.7km from Seneca, and feel the excitement of college sports. Immerse yourself in the spirited atmosphere and witness thrilling games while taking in the local culture. ### Best time to go to Seneca Visitor numbers in Seneca is generally unchanged in popularity throughout the year. The best time to visit Seneca can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Seneca falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Seneca falls in January, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 41.7°F (5.4°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 45.7°F (7.6°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 52.0°F (11.1°C) | Light Rain | Mostly Sunny | Average | Average | | April | 59.9°F (15.5°C) | Light Rain | Mostly Sunny | Average | Average | | May | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Average | Average | | June | 75.7°F (24.3°C) | Light Rain | Mostly Sunny | Slightly High | Average | | July | 79.2°F (26.2°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 77.4°F (25.2°C) | Light Rain | Mostly Sunny | Average | Average | | September | 72.1°F (22.3°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | October | 62.1°F (16.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | December | 45.7°F (7.6°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Seneca For your visit to Seneca, South Carolina, you can fly into two major airports. Greenville-Spartanburg International Airport ([GSP](https://www.expedia.ca/Greenville-Spartanburg-Intl-Airport-Hotels.0-aGSP-0.Travel-Guide-Filter-Hotels)) is located 70.8km away and offers convenient hotel options like the 4-star [Greenville Marriott](https://www.expedia.ca/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information), just 4.8km from the airport, as well as the 3.5-star Crowne Plaza Hotel and [Hilton Greenville](https://www.expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information), both 11.3km away. Alternatively, Asheville Regional Airport ([AVL](https://www.expedia.ca/Asheville-Regional-Airport-Hotels.0-aAVL-0.Travel-Guide-Filter-Hotels)), situated 511.3km from Seneca, features excellent accommodations such as the 4.5-star [Grand Bohemian Asheville](https://www.expedia.ca/Asheville-Hotels-Grand-Bohemian-Asheville.h2201799.Hotel-Information), located 14.5km away, and the charming [Abbington Green Bed & Breakfast Inn](https://www.expedia.ca/Asheville-Hotels-Abbington-Green-Bed-Breakfast-Inn.h9711374.Hotel-Information), 19.3km from the airport. Both airports provide accessible transport services to these hotels. ## Recent reviews of Seneca hotels ![Tru by Hilton Seneca Clemson](//images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8_y.jpg) ### Tru by Hilton Seneca Clemson 5/5 Excellent "Stayed one night for visit with Son at Clemson, everything was good, friendly staff, clean room and good breakfast." A verified traveller stayed at Tru by Hilton Seneca Clemson Posted 2 days ago [](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Fabulous Tiny House with AC in charming Seneca](//images.trvl-media.com/lodging/119000000/118480000/118477500/118477441/c3793bf2_y.jpg) ### Fabulous Tiny House with AC in charming Seneca 5/5 Excellent "Enjoyed our stay. Tiny house was perfect for two people. Very quiet and enjoyed the wildlife walking through the yard. Had a nice campfire one night. Would definitely recommend this to anybody most and likely will rent it again when we come back" A verified traveller stayed at Fabulous Tiny House with AC in charming Seneca Posted 2 days ago [](https://expedia.ca/Seneca-Hotels-Fabulous-Tiny-House-With-AC-In-Charming-Seneca.h118477441.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](//images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 5/5 Excellent "Great " A verified traveller stayed at Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy Posted 2 days ago [](https://expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Lakeside Lodge Clemson](//images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff_y.jpg) ### Lakeside Lodge Clemson 5/5 Excellent "Exceeded my expectations! I will be staying here again. " A verified traveller stayed at Lakeside Lodge Clemson Posted 3 days ago [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub](//images.trvl-media.com/lodging/62000000/61650000/61640700/61640625/6343a107_y.jpg) ### Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub 5/5 Excellent "Beautiful house with most amenities we have ever had at a VRBO. Neighborhood is very nice and private with beautiful views of lake and mountains. We wish we had more time- there was so much more to do we never got the chance to get to. Hopefully we can make it back here in the summer!" A verified traveller stayed at Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub Posted 4 days ago [](https://expedia.ca/Seneca-Hotels-Beautiful-Waterfront-Home-On-A-Private-Cove-In-Lake-Keowee-W-Hot-Tub.h61640625.Hotel-Information) ![4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. ](//images.trvl-media.com/lodging/34000000/33730000/33728200/33728167/be98782f_y.jpg) ### 4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. 5/5 Excellent "The home is located on a beautiful, quiet cove of Lake Keowee. The house was well stocked and comfortable. We had great communication with the hosts and check in was easy. Clemson University is about 30 minutes from the home. " A verified traveller from Fort Myers, FL stayed at 4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. Posted 9 days ago [](https://expedia.ca/Anderson-Hotels-Beautiful-43.h33728167.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](//images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg) ### Quality Inn Seneca Clemson Area US-123 5/5 Excellent "Ok" A verified traveller stayed at Quality Inn Seneca Clemson Area US-123 Posted 10 days ago [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Fairfield Inn & Suites Seneca Clemson Univ Area ](//images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894_y.jpg) ### Fairfield Inn & Suites Seneca Clemson Univ Area 5/5 Excellent "Very " A verified traveller stayed at Fairfield Inn & Suites Seneca Clemson Univ Area Posted 12 days ago [](https://expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](//images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/fbdc7d33_y.jpg) ### New to VRBO! Big water views, private dock, pool table, 15 min Clemson! 5/5 Excellent "We had an amazing time with our family (9 adults) at this beautiful house on a peaceful cove at Lake Keowee. So many activities are available in the area. We rented a pontoon boat from Lake Day Rentals (highly recommend them!) and had so much fun exploring the lake as well as tubing. House provided kayaks, paddle boards, and floats which was so nice to access. The house has so many nice places to hang out and take in the waterviews which are fantastic. Nearby we took in some golf at the Walker course at Clemson (top notch experience), mountain biked at Stumphouse trails, played pickleball in Walhalla, and found some great brewery's. Back to the house: it really has everything we needed. We cooked all our meals (shop at Publix, 15 mins away and really nice) and found the kitchen so well equipped, clean and spacious. 6 smart TV's and a pool table made for great entertainment as well. Really can't say enough about the house and would add that Doug and Beth are great hosts and clearly know how to set up a house for maximum fun with zero hassle for their guests. We plan on returning!" A verified traveller stayed at New to VRBO! Big water views, private dock, pool table, 15 min Clemson! Posted 2 weeks ago [](https://expedia.ca/Anderson-Hotels-Large.h57941024.Hotel-Information) ## Frequently asked questions ### How much does a spa hotel in Seneca cost? > Enjoy staying in a spa hotel in Seneca, with plenty of hotels from CA $92 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays. ### Is it cheaper to book a spa hotel in Seneca with flights as part of a package deal? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect [travel package](https://www.expedia.ca/Seneca.d6548.Destination-Travel-Guides). ### Are there any unique spa experiences available in Seneca? > Yes, Seneca, South Carolina offers several unique spa experiences, particularly through specialised aesthetic and wellness clinics. > > > > Jocassee Hydration & Aesthetics in downtown Seneca provides advanced treatments such as facial fillers, microneedling with platelet rich fibrin (PRF), and natural facial treatments. They also offer an "Eye of the Tiger intravenous therapy" designed to boost energy and mood, a distinctive wellness option. > > > > The Refinery Co., an aesthetic clinic, focuses on advanced skin care procedures including chemical peels, diamond dermabrasion facials, and hydrofacials. Their approach combines personalised care with modern technology for a unique medspa experience. > > > > Tony Massage & Salon, LLC and Your Contoured Body also contribute to the local wellness scene, offering massage and body contouring services respectively. ### How can I save on a spa hotel in Seneca with Expedia? > Members always get our best prices. Find our best Seneca spa hotel deals by joining Expedia's free travel rewards program—[One Key™](https://www.expedia.ca/welcome-one-key). As a member, you can unlock instant savings and member perks when you're logged in to your account. For a spontaneous weekend retreat, discover last-minute offers. ### Can I cancel my spa hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Seneca for you. ### What amenities should I look for in a pet-friendly hotel in Seneca? > When selecting a hotel in Seneca for you and your pet, look for amenities like food and water bowls, pet-friendly outdoor spaces and pet beds. You may find hotels that go the extra mile with pet-friendly dining options, treats and toys. It's also worth looking to see if there are any pet-friendly parks or walking trails nearby. ### How can I save on a pet-friendly hotel in Seneca with Expedia? > There are plenty of ways to save on a pet-friendly hotel in Seneca. Join [One Key™](https://www.expedia.ca/welcome-one-key)—Expedia's free travel rewards program—to unlock discounted Member Prices. Typically, booking in advance will help you save on your pet-friendly hotel booking. ### Do any Seneca hotels have restrictions on pet sizes or breeds? > First ensure you have picked a pet-friendly hotel by using the "Pet friendly" filter under the "Amenities" section in your search. If a hotel in Seneca has restrictions on pet sizes or breeds, you will find this information clearly in their property listing on Expedia. When you're on the property listing page, simply click on "Policies" to see what pet-specific policies the hotel implements. ### Is it cheaper to book flights and a pet-friendly hotel in Seneca as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Can I cancel my pet-friendly hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)