Title: Seneca Vacation Rentals from CA $210: Short-Term Rentals for 2026 | Expedia.ca

[Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides)

![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check prices for these dates

In two weeks

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Seneca vacation rentals

![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/cf119645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Queen Bed (View) | Private kitchen](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

Seneca

9.8/10

Exceptional

(66 reviews)

"Excellent stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beonca

CA $136

CA $210 total

includes taxes & fees

Apr 16 - Apr 17

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/511c9b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/c9812bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/ad885ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Clemson TIny House Cabin

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

Seneca

CA $172

CA $299 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/ec808a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/45872750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Clemson Cottage - 3.6 mi. to Memorial Stadium

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

Seneca

10/10

Exceptional

(16 reviews)

"Seriously comfortable home, the beds and pillows all fantastic, nicely appointed in every way. Can’t wait to stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

CA $247

CA $542 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/bc9bfba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/8a811318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/518d0c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

Seneca

10/10

Exceptional

(9 reviews)

"We enjoyed our stay. Had everything we needed. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Diane S.

CA $336

CA $722 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/7bfcd263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/fa054611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/8d32bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, table tennis](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/1692b12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

Seneca

10/10

Exceptional

(6 reviews)

"Great place with a lot close by"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aldor D.

CA $309

CA $456 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/e2e2f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

Seneca

8.8/10

Excellent

(5 reviews)

"Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alisa W.

CA $225

CA $403 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/fc891652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d37b415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/d33a6537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/f0fe695d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

Seneca

9.6/10

Exceptional

(8 reviews)

"Very accommodating host. Property is a great location and very clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig F.

CA $448

CA $954 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information)

![4 bedrooms, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/41018e46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/3ef9dbf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/aad65738.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, printers](https://images.trvl-media.com/lodging/115000000/114850000/114843800/114843702/d0ce4a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Johnsons Cove - Lakefront Retreat With EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca G.

CA $453

CA $1,049 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Johnsons-Cove-Lakefront-Retreat-With-EV-Charger.h114843702.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/436516e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/345ab4fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/9428aa30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/ff2ee17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Keowee Adventures \~ Peaceful Lakefront Home on Keowee \~ 7 Miles from Clemson!

[](https://www.expedia.ca/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information)

Seneca

9.8/10

Exceptional

(59 reviews)

"We had a beautiful stay over Thanksgiving in this very cozy lake house. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Felicia L.

CA $493

CA $848 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information)

![Smart TV, video games, table tennis](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/eea5ec7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/86d085c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/c53fb178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/98000000/97060000/97053600/97053582/5f42512b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

[](https://www.expedia.ca/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information)

Seneca

10/10

Exceptional

(21 reviews)

"Very nice accommodations and great location for stay in Clemson. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marisa G.

CA $178

CA $524 total

includes taxes & fees

Apr 14 - Apr 15

[](https://www.expedia.ca/Seneca-Hotels-Lakeside-Clemson-Condo-With-4KSurround-SoundXboxCoffee-BarPrivate-Bathrooms.h97053582.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/644a4539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

Serenity Bay

9.8/10

Exceptional

(130 reviews)

"Beautiful home, well furnished, very clean, easy TV"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alan

CA $515

CA $983 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/b866198b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/998168ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/3e3661cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Marina](https://images.trvl-media.com/lodging/38000000/37020000/37012900/37012874/c09b9ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Keowee Retreat! Swim, Boat, Kayak & Relax on Dock Just Steps from the Water

[](https://www.expedia.ca/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information)

Seneca

10/10

Exceptional

(82 reviews)

"Nice location and functionality for family. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

T P.

CA $717

CA $1,246 total

includes taxes & fees

Apr 4 - Apr 5

[](https://www.expedia.ca/Seneca-Hotels-LAKE-FRONT-RETREAT-Steps-Away-From-Swimming.h37012874.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/f084865a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/686661ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/06dbf16e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/128000000/127020000/127013800/127013757/9bb2205c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Family Home in a Quiet Setting-12 Minutes from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-A-Cozy-Family-Home-With-A-Relaxing-Stay-In-A-Quiet-Setting.h127013757.Hotel-Information)

Seneca

CA $216

CA $433 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Seneca-Hotels-A-Cozy-Family-Home-With-A-Relaxing-Stay-In-A-Quiet-Setting.h127013757.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/967698a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/28115a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/5507d727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/106000000/105170000/105164100/105164063/3b0074de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seneca lake house with private dock only 15 minutes from Clemson!

[](https://www.expedia.ca/Seneca-Hotels-Seneca-Lake-House-With-Private-Dock-Only-15-Minutes-From-Clemson.h105164063.Hotel-Information)

Seneca

9.8/10

Exceptional

(10 reviews)

"We had a great time at Seneca Lake House. We would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Scott M.

CA $432

CA $1,061 total

includes taxes & fees

Mar 26 - Mar 27

[](https://www.expedia.ca/Seneca-Hotels-Seneca-Lake-House-With-Private-Dock-Only-15-Minutes-From-Clemson.h105164063.Hotel-Information)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/5fc6414e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c2f5c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/b1844261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  Enjoy one of our RV units son less of a headache for you this vacation!

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

Seneca

8.0/10

Very good

(4 reviews)

"My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise s.

CA $112

CA $229 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/424e1883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/e2588273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/4513793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

Seneca

10/10

Exceptional

(12 reviews)

"Very clean and comfortable - very close to Clemson and easy access. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jim A.

CA $206

CA $273 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/891c0bf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/e8c5c43f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/fbb953e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/126000000/125630000/125624500/125624500/2d71c6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  bedroom available in my house in lovely Seneca. 5 miles from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"Rooms were clean and host was accommodating. Room to park my boat and was able to bring my dog!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew A.

[](https://www.expedia.ca/Seneca-Hotels-Charming-1-Bedroom-House-In-Lovely-Seneca-5-Miles-From-Clemson-University.h125624500.Hotel-Information)

![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/9e2b77c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/651434b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/a5e27533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/d1bcfdf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

Downtown

10/10

Exceptional

(16 reviews)

"Great home base for a Clemson game. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen A.

CA $219

CA $467 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information)

![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/c027128d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/84d2a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/9e13146e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/120000000/119750000/119746400/119746321/1ece8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Big Golf House- 10 miles to Clemson

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

Seneca

10/10

Exceptional

(2 reviews)

"Absolutely! Perfect space for our needs, so for accommodating for our family & pet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gennifer Q.

CA $380

CA $809 total

includes taxes & fees

Apr 14 - Apr 15

[](https://www.expedia.ca/Seneca-Hotels-The-Big-Seneca-Golf-House-7-Miles-To-Death-Valley.h119746321.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/39da46e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, video library](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/ff6eb6d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/d6399ba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/127000000/126990000/126982700/126982607/482da2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Cottage Retreat-12 Minutes from Clemson University

[](https://www.expedia.ca/Seneca-Hotels-Carolina-Cottage-Retreat.h126982607.Hotel-Information)

Seneca

CA $220

CA $437 total

includes taxes & fees

Mar 31 - Apr 1

[](https://www.expedia.ca/Seneca-Hotels-Carolina-Cottage-Retreat.h126982607.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&regionId=6548&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO)

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VILLA)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=HOUSE_BOAT)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America&regionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)

## Top Seneca Hotel Reviews

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

8/10 Good

"Everything was nice"

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](https://images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/eb68ea9e_y.jpg)

### New to VRBO! Big water views, private dock, pool table, 15 min Clemson!

10/10 Excellent

"We enjoyed our stay at your property very much.Everything was exceptionally clean and well taken care of. Thank you for quickly addressing the issue with the heat pump."

[](https://expedia.ca/Anderson-Hotels-Large.h57941024.Hotel-Information)

![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg)

### Inn @ Clemson

10/10 Excellent

"All of the staff we encountered were extremely nice and helpful. The beds were very comfortable thoroughly enjoyed our stay."

[](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information)

![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg)

### Lakeside Lodge Clemson

10/10 Excellent

"The unit was terrific. Quiet and clean. only issue is daily train whistle nearby. Nice area with grrat restaurant in hotel. "

[](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg)

### The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Loved our time here! Staff was super sweet and helpful. Room was very nice and the bed very cozy. Room felt a little small but the bathroom was larger than expected, and again all nice and clean. No complaints! Great place to stay when in the area! Love the mission to help those differently abled, as well!!"

[](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information)

![Best Western Seneca-Clemson](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a_y.jpg)

### Best Western Seneca-Clemson

10/10 Excellent

"Clean room! Great staff! "

[](https://expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information)

![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283_y.jpg)

### Tru by Hilton Seneca Clemson

10/10 Excellent

"Clean room, friendly staff. Great place to stay!"

[](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

![Fairfield Inn & Suites Seneca Clemson Univ Area    ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5_y.jpg)

### Fairfield Inn & Suites Seneca Clemson Univ Area 

10/10 Excellent

"Clean room freindly staff and convenient location to stores"

[](https://expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit,  Pet Friendly!](https://images.trvl-media.com/lodging/34000000/33730000/33728200/33728167/7de7c272_y.jpg)

### 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

10/10 Excellent

"The home was beautiful, the amenities fantastic, and we especially enjoyed the kayaks! The kitchen was also stocked with all the basics we needed which saved us from additional grocery expense for items we would only be using for a couple of days. The owner was also a delight to work with. Wonderful experience!"

[](https://expedia.ca/Anderson-Hotels-Beautiful-43.h33728167.Hotel-Information)

## Find out more about Seneca

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Seneca. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

## Explore a world of travel with Expedia

- Trending destinations on Expedia.ca
- All accommodation types in Seneca

### Trending destinations on Expedia.ca

- [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals)
- [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals)
- [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Tofino Vacation Rentals ](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals)
- [Calgary Vacation Rentals ](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals)
- [Costa Rica Vacation Rentals ](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations)
- [Vancouver Island Vacation Rentals ](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals)
- [Puerto Vallarta Vacation Rentals ](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals)
- [Hawaii Vacation Rentals ](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Toronto Vacation Rentals ](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals)
- [Banff Vacation Rentals ](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals)
- [Penticton Vacation Rentals ](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals)
- [Osoyoos Vacation Rentals ](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals)
- [Mont Tremblant Vacation Rentals ](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals)
- [Big White Ski Resort Vacation Rentals ](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals)
- [Ontario Vacation Rentals ](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations)
- [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
- [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

- [Vacation Homes in Seneca ](https://expedia.ca/Seneca-Private-Vacation-Homes.d6548-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cottages in Seneca ](https://expedia.ca/Seneca-Cottages.d6548-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in Seneca ](https://expedia.ca/Seneca-Cabins.d6548-aaCabins.Travel-Guide-Accommodation)
- [Apartments in Seneca ](https://expedia.ca/Seneca-Apartments.d6548-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Seneca ](https://expedia.ca/Seneca-Condos.d6548-aaCondos.Travel-Guide-Accommodation)
- [Villas in Seneca ](https://expedia.ca/Seneca-Villas.d6548-aaVillas.Travel-Guide-Accommodation)
- [Motels in Seneca ](https://expedia.ca/Seneca-Motels.d6548-aaMotels.Travel-Guide-Accommodation)
- [Farmstay in Seneca ](https://expedia.ca/Seneca-Agritourism.d6548-aaAgritourism.Travel-Guide-Accommodation)
- [Lodges in Seneca ](https://expedia.ca/Seneca-Lodges.d6548-aaLodges.Travel-Guide-Accommodation)
- [RV Parks in Seneca ](https://expedia.ca/Seneca-RV-Parks.d6548-aaRVParks.Travel-Guide-Accommodation)
- [B&B in Seneca ](https://expedia.ca/Seneca-Bed-And-Breakfast.d6548-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Guest Houses in Seneca ](https://expedia.ca/Seneca-Guest-Houses.d6548-aaGuestHouses.Travel-Guide-Accommodation)
- [Chalets in Seneca ](https://expedia.ca/Seneca-Chalets.d6548-aaChalets.Travel-Guide-Accommodation)
- [Houseboats in Seneca ](https://expedia.ca/Seneca-Houseboats.d6548-aaHouseboats.Travel-Guide-Accommodation)
- [Aparthotels in Seneca ](https://expedia.ca/Seneca-Apart-Hotels.d6548-aaApartHotels.Travel-Guide-Accommodation)
- [Condo Resorts in Seneca ](https://expedia.ca/Seneca-Condominium-Resort.d6548-aaCondominiumResort.Travel-Guide-Accommodation)

## Frequently asked questions

### Are there vacation rentals in Seneca?

### What's the top vacation rental in Seneca?

### How many vacation rentals are there in Seneca?

### What’s there to see and do in Seneca?

### What’s a vacation rental in Seneca like?

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app