Title: 2 Stars Hotels in Seneca, South Carolina from CA $78 - Find Cheap Seneca Hotels With 2 Stars | Expedia.ca [Seneca Travel Guide](https://expedia.ca/Seneca.dx6548)[Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![An overlooking view in Seneca, South Carolina](https://images.trvl-media.com/place/6548/dae46ccf-db63-4268-bbdf-1e7406fb8f30.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6548/dae46ccf-db63-4268-bbdf-1e7406fb8f30.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Seneca 2 Star Hotels Tonight [Jan 12 - Jan 13](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-12&endDate=2026-01-13&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 13 - Jan 14](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-13&endDate=2026-01-14&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-23&endDate=2026-01-25&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Seneca 2-star hotels ![Studio Suite, 1 King Bed, Non Smoking | Jetted tub](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/bea0c9d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/0cd0388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/9c84c468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/18069cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) Anderson 7.8/10 Good (1,001 reviews) "Very nice we'll stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $87 CA $97 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-ce9cc597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-f00c0668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) Clemson 8.2/10 Very good (1,000 reviews) "Clean room and staff were great’" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Audrey CA $132 CA $147 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Seneca 8.0/10 Very good (668 reviews) "Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $105 CA $124 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/60d71ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/4f8e319f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/330446c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/3e3a13ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) Clemson 8.2/10 Very good (1,002 reviews) "Clean and convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olga CA $142 CA $158 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/59f41330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2f0ad17a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/2b4321e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/0a2d26b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Anderson 8.2/10 Very good (1,001 reviews) "Room was clean, front desk people were very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caressa CA $105 CA $117 total includes taxes & fees Jan 15 - Jan 16 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1,000 reviews) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $151 CA $188 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/269fcec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/5926289d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/c069e415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/d03a9275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Clemson near University [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) Anderson 7.0/10 Good (893 reviews) "Bueno was " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Alejandro CA $73 CA $81 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/ca1bd62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/8ea6d425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/816f82a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Easley/Greenville [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) Easley 7.4/10 Good (764 reviews) "Easy access from the highway lot of restaurants around the hotel and staff is very friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) brian CA $94 CA $104 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/dac98c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) Seneca 6.8/10 (724 reviews) "Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $103 CA $113 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/34438b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/f1cbacdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/01f08951.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) Clemson 8.0/10 Very good (1,006 reviews) "Staff and hotel was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keren [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/813e9213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/971b0081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/5a22cd65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/b60fead8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Anderson Clemson [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) Anderson 7.0/10 Good (849 reviews) "Well lit parking and safe area around the hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $83 CA $92 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/31a466c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/a60da822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/8cef3eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/00a58c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Anderson by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) Anderson 8.6/10 Excellent (385 reviews) "Convenient location to I-85, quiet with nice parking area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $146 CA $162 total includes taxes & fees Jan 16 - Jan 17 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/9bab6d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0c8d8851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0160650e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) Anderson 9.0/10 Wonderful (586 reviews) "It was great. Room was clean and staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica CA $143 CA $159 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Seneca 8.4/10 Very good (645 reviews) "The stay was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha CA $117 CA $129 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/62fa3a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/b202edd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/ac7a917f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) Seneca 9.2/10 Wonderful (803 reviews) "Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy CA $146 CA $161 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/7c6944d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/45e916fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Smoking](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/501aacf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/85d098d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Easley/Greenville/Clemson Area [](https://www.expedia.ca/Easley-Hotels-Days-Inn-By-Wyndham-EasleyGreenvilleClemson-Area.h25561.Hotel-Information) Easley 6.2/10 (825 reviews) "It was like always pretty ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sasha CA $90 CA $100 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Easley-Hotels-Days-Inn-By-Wyndham-EasleyGreenvilleClemson-Area.h25561.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/e417f297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/66ea89ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queens](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/91fb1400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Anderson/ Alliance Business Park [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) Anderson 9.2/10 Wonderful (814 reviews) "Staff, Just a Nice Hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $152 CA $169 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/3e5b0e7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/22ac8c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/f281928a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/a12c8c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Lavonia [](https://www.expedia.ca/Hartwell-Hotels-Hampton-Inn-Suites-Lavonia.h9105285.Hotel-Information) Lavonia 9.0/10 Wonderful (383 reviews) "Room was clean and staff was very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) clay CA $159 CA $189 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Hartwell-Hotels-Hampton-Inn-Suites-Lavonia.h9105285.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/020b11bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/ae3f38f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/4ea5cb8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/1611bef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Horizon Inn & Suites [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) Anderson 4.6/10 (246 reviews) "Staff there is awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $67 CA $78 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/81e73e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/2c84c92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (205 reviews) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $173 CA $191 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Seneca-Hotels.s20-0-d6548.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Seneca-Hotels.s20-0-d6548.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Seneca. ![Hilton Garden Inn Anderson](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Anderson 115 Destination Blvd Anderson SC CA $147 CA $163 total Jan 26 - Jan 27 includes taxes & fees 8.8/10 Excellent! (689 reviews) [](https://expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Home2 Suites by Hilton Anderson Downtown](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/0f86ef1c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Home2 Suites by Hilton Anderson Downtown 315 S Main St Anderson SC CA $195 CA $216 total Jan 25 - Jan 26 includes taxes & fees 9.2/10 Wonderful! (221 reviews) [](https://expedia.ca/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information) ![Clemson University's James F. Martin Inn](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Clemson University's James F. Martin Inn 240 Madren Center Drive Clemson SC CA $207 CA $230 total Jan 26 - Jan 27 includes taxes & fees 9.4/10 Exceptional! (961 reviews) [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Still don't see what you're looking for? [See all properties in Seneca.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6548&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Seneca Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons. [See all hotels in Seneca](https://www.expedia.ca/Hotel-Search?startDate=2026-01-27&endDate=2026-01-28&adults=2®ionId=6548) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=899&h=314&p=1&q=high) ## Top Seneca Hotel Reviews ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Nice for price. Nice staff. " [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "Excellent stay." [](https://expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Days Inn by Wyndham Seneca / Clemson Area](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a_y.jpg) ### Days Inn by Wyndham Seneca / Clemson Area 10/10 Excellent "Very nice and helpful at the fronte desk. Nice room and very comfortable bed" [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ## Find out more about Seneca Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Seneca, Seneca you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions. Several of the best hotels with 2 Stars in Seneca are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. 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