Title: 2 Stars Hotels in Seneca, South Carolina from CA $76 - Find Cheap Seneca Hotels With 2 Stars | Expedia.ca [Seneca Travel Guide](https://expedia.ca/Seneca.dx6548)[Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![An overlooking view in Seneca, South Carolina](https://images.trvl-media.com/place/6548/dae46ccf-db63-4268-bbdf-1e7406fb8f30.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # 2 Stars Hotels in Seneca, South Carolina from CA $76 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Seneca 2 Star Hotels Tonight [Jan 5 - Jan 6](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-05&endDate=2026-01-06&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 6 - Jan 7](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-06&endDate=2026-01-07&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=20&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Seneca 2-star hotels ![Deluxe Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/0ef49c04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/9c84c468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/0cd0388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/552400b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Anderson [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) Anderson 7.8/10 Good (1005) "Very nice we'll stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $86 CA $96 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) Clemson 8.2/10 Very good (1005) "Clean room and staff were great’" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Audrey CA $127 CA $141 total includes taxes & fees Jan 8 - Jan 9 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/3c50d204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/270-2efd6ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Downtown 8.0/10 Very good (667) "Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $104 CA $122 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/6228400c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) Clemson 8.2/10 Very good (1002) "Great area behind the hotel to walk my dog!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie CA $141 CA $156 total includes taxes & fees Jan 13 - Jan 14 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/706f626f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/452fcf9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/94f8bd4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Anderson/Clemson [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) Anderson 8.2/10 Very good (1002) "Room was clean, front desk people were very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caressa CA $104 CA $115 total includes taxes & fees Jan 14 - Jan 15 [](https://www.expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/9732d3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/d191b963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Resort Studio with Kitchen and Two Queen | Private kitchen](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/70e13494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1000) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene CA $150 CA $186 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/01de7c97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/6549b5eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/743fe535.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/b0243d51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Clemson near University [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) Anderson 7.0/10 Good (893) "Bueno was " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Alejandro CA $69 CA $76 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/2d87513f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/ca1bd62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Single Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/570000/569400/569381/4ce574a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Easley/Greenville [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) Easley 7.4/10 Good (762) "Easy access from the highway lot of restaurants around the hotel and staff is very friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) brian CA $103 CA $114 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) Seneca 6.8/10 (723) "Room was clean. Quiet place to rest. Lisa at the front desk was very helpful and very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $102 CA $112 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/3e16f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/1c4bc101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/10c576cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) Clemson 8.0/10 Very good (1003) "Staff and hotel was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keren [](https://www.expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/b60fead8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/3a6df04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/5a22cd65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/540000/533900/533878/813e9213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Anderson Clemson [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) Anderson 7.0/10 Good (847) "Well lit parking and safe area around the hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $82 CA $91 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Anderson-Hotels-Baymont-By-Wyndham-Anderson-Clemson.h533878.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/9b02734a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/31a466c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/8cef3eda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/5600/5547/d4e27826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Anderson by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) Anderson 8.6/10 Excellent (385) "Convenient location to I-85, quiet with nice parking area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $144 CA $160 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Anderson.h5547.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/389cca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4c01aca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0c8d8851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) Anderson 9.0/10 Wonderful (586) "It was great. Room was clean and staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica CA $119 CA $133 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed)](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) Seneca 8.4/10 Very good (644) "The stay was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha CA $123 CA $135 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/10f1fcf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible (Hearing, Roll-In Shower)](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/d36e662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/2bb8d81a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/ac7a917f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) Seneca 9.2/10 Wonderful (801) "Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy CA $144 CA $159 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/7c6944d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/d29fb534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/45e916fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25561/f001fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Easley/Greenville/Clemson Area [](https://www.expedia.ca/Easley-Hotels-Days-Inn-By-Wyndham-EasleyGreenvilleClemson-Area.h25561.Hotel-Information) Easley 6.2/10 (825) "It was like always pretty ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sasha CA $95 CA $106 total includes taxes & fees Jan 7 - Jan 8 [](https://www.expedia.ca/Easley-Hotels-Days-Inn-By-Wyndham-EasleyGreenvilleClemson-Area.h25561.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/60389240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/52035ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/a3e9e5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Anderson/ Alliance Business Park [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) Anderson 9.2/10 Wonderful (812) "Staff, Just a Nice Hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $144 CA $160 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/79c31c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/f281928a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/217e0610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/10000000/9110000/9105300/9105285/de2a36d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Lavonia [](https://www.expedia.ca/Hartwell-Hotels-Hampton-Inn-Suites-Lavonia.h9105285.Hotel-Information) Lavonia 9.0/10 Wonderful (383) "Room was clean and staff was very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) clay CA $173 CA $206 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Hartwell-Hotels-Hampton-Inn-Suites-Lavonia.h9105285.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/1611bef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/710f38aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/020b11bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/10000/6500/6496/b7ec145d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Horizon Inn & Suites [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) Anderson 4.6/10 (244) "Staff there is awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $66 CA $77 total includes taxes & fees Jan 11 - Jan 12 [](https://www.expedia.ca/Anderson-Hotels-Horizon-Inn-Suites.h6496.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (205) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $172 CA $189 total includes taxes & fees Jan 12 - Jan 13 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Seneca-Hotels.s20-0-d6548.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F2Star-Seneca-Hotels.s20-0-d6548.Travel-Guide-Filter-Hotels) ## Explore similar 3-star hotels Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Seneca. ![Hilton Garden Inn Anderson](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/78e2a715_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hilton Garden Inn Anderson 115 Destination Blvd Anderson SC CA $145 CA $161 total Jan 12 - Jan 13 includes taxes & fees 8.8/10 Excellent! (686 reviews) [](https://expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information) ![Home2 Suites by Hilton Anderson Downtown](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/0f86ef1c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Home2 Suites by Hilton Anderson Downtown 315 S Main St Anderson SC CA $192 CA $213 total Jan 11 - Jan 12 includes taxes & fees 9.2/10 Wonderful! (220 reviews) [](https://expedia.ca/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information) ![Clemson University's James F. Martin Inn](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Clemson University's James F. Martin Inn 240 Madren Center Drive Clemson SC CA $205 CA $227 total Jan 7 - Jan 8 includes taxes & fees 9.4/10 Exceptional! (961 reviews) [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Still don't see what you're looking for? [See all properties in Seneca.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20&star=20&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20&star=20&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20&star=20&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20&star=20&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=07%2F01%2F2026&endDate=08%2F01%2F2026®ionId=6548&star=20&star=20&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Seneca Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons. [See all hotels in Seneca](https://www.expedia.ca/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21&adults=2®ionId=6548) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=899&h=314&p=1&q=high) ## Top Seneca Hotel Reviews ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Love it" [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "Excellent stay." [](https://expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Days Inn by Wyndham Seneca / Clemson Area](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/9f69229a_y.jpg) ### Days Inn by Wyndham Seneca / Clemson Area 10/10 Excellent "Very nice and helpful at the fronte desk. Nice room and very comfortable bed" [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ## Find out more about Seneca Want to get out of town on the cheap? Thanks to the low rates and great discounts at the top 2 Stars hotels in Seneca, Seneca you can sneak away on the trip of your dreams with plenty of cash to spare. In addition to the friendly staff and well-maintained surroundings, you’ll find comfortable rooms, complimentary bath products, and quiet sleeping areas, so you can kick back with all the basic conveniences after a long day. Plus, these properties are perfect, if you need a jumping-off point for exploring the local attractions. Several of the best hotels with 2 Stars in Seneca are situated just a stone’s throw from both public transportation and the city’s main freeways. Use the travel tools at Expedia.ca to search for options near your favorite neighborhood, find a cheap deal, and book your room. 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