Title: Book the Best Seneca FAMILY FRIENDLY Hotels from CA $98 - Kid-Friendly Hotels in Seneca, SC | Expedia.ca [Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Things to do in Seneca](https://expedia.ca/Things-To-Do-In-Seneca.d6548.Travel-Guide-Activities)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/29e46f4f8050a1df2512f3a6a1598c99.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Cindy Keese # Find Family Hotels in Seneca, SC from CA $98 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Seneca Family Hotels Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-14&endDate=2025-10-15&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-15&endDate=2025-10-16&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2025-10-24&endDate=2025-10-26&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Seneca Family Hotels ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area Seneca 9.4/10 Exceptional (196) "Nice hotel by the lake" CA $181 CA $199 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![3 bedrooms, travel crib, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/425cdbc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/9e2b77c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/a5e27533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105770000/105769700/105769612/a25c3100.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Downtown 10/10 Exceptional (15) "Wonderful hosts and a great home. Very close to downtown Seneca and Clemson. Clean house with a great layout. Highly recommend!" CA $253 CA $514 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Seneca-Hotels-Renovated-Bungalow-1-Block-From-Downtown-Seneca-8-Miles-From-Clemson.h105769612.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/56040807.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/ab8a784d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/57b2b9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118710000/118705000/118704946/e11883a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson Seneca 10/10 Exceptional (3) "Great place with a lot close by" CA $251 CA $424 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Seneca-Hotels-3-Bedroom-2-Bath-Home-Located-Minutes-From-Keowee-Mariana.h118704946.Hotel-Information) ![5 bedrooms, travel crib, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101790000/101785400/101785318/fac42006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101790000/101785400/101785318/5553129d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101790000/101785400/101785318/bb296007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101790000/101785400/101785318/993026f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Cabin on Lake Keowee. Kayaks, paddle boards, modern & cozy! Seneca 10/10 Exceptional (15) "We had a wonderful 3 night stay! " CA $354 CA $880 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Seneca-Hotels-Lakefront-Cabin-On-Lake-Keowee-Kayaks.h101785318.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/10afe7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/a1808626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger Serenity Bay 9.8/10 Exceptional (126) "A wonderful stay! The house offered many different spaces and the lake access/dock was perfect!!" CA $490 CA $952 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/299db208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/ac405b8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/9b76782a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107520000/107517300/107517282/3a34d432.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium Seneca 9.4/10 Exceptional (6) "Perfect for visiting Clemson student. Great location, clean, and well stocked. Owners were very responsive. Would definitely stay here again!" CA $528 CA $1,061 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Seneca-Hotels-Beautiful-Updated-Clemson-Lake-House-5-Mins-From-Downtown-Clemson-And-The-Stadium.h107517282.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/389cca02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/4c01aca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0c8d8851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG Anderson 9.0/10 Wonderful (570) "Good breakfast, clean " CA $145 CA $161 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/620a9c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/ebee5c42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/aacced25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4590000/4584800/4584724/87ef0209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Anderson 7.8/10 Good (302) "We came into town for a busy weekend and this was perfect for our needs without breaking the bank. Polite reception and a really comfy bed. " CA $88 CA $98 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Anderson-Hotels-Rodeway-Inn.h4584724.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/ca80b104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/7f8f2b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/76bc86a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area Clemson 8.2/10 Very good (1004) "Awesome place to stay" CA $136 CA $151 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/1d8e7ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/13d01f75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/316c434e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/800000/794500/794424/33737158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Anderson Clemson Anderson 9.0/10 Wonderful (560) "Clean room staff was verynice!" CA $188 CA $209 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Anderson-Hotels-Fairfield-Inn-Suites-By-Marriott-Anderson-Clemson.h794424.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29®ionId=6548&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Seneca Hotel Reviews ![Hampton Inn & Suites Seneca-Clemson Area](//images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "Great place to stay" [](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Best Western Seneca-Clemson](//images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0_y.jpg) ### Best Western Seneca-Clemson 10/10 Excellent "We had a nice stay. " [](https://expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Fall fun at the cabin! Convenient to Lake Keowee and Clemson](//images.trvl-media.com/lodging/19000000/18970000/18968900/18968828/9c91f86d_y.jpg) ### Fall fun at the cabin! Convenient to Lake Keowee and Clemson 10/10 Excellent "It was a lovely place to stay!" [](https://expedia.ca/Anderson-Hotels-Fall-Fun-At-The-Cabin-Convenient-To-Lake-Keowee-And-Clemson.h18968828.Hotel-Information) ## Frequently asked questions ### What's Seneca like for family-friendly vacations? > The welcoming destination of Seneca is a good choice if you've been considering a getaway with your kids. The boating, lake views, and sporting events are just some of the things that make this the perfect spot for family trips. Fly into Greenville-Spartanburg Intl. Airport (GSP), which is located 44.1 mi (71 km) from the city center. ### What's the best accommodation for families in Seneca? > [Fairfield Inn & Suites Seneca Clemson Univ Area](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. ### When's the best time to book a family-friendly vacation in Seneca? > The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches. ### What's there to see and do with your family in Seneca? > While you and your family are vacationing in Seneca, you might want to visit some family-friendly attractions such as Oconee County Library Seneca Branch and The Gauntlet. 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