Santa Maria Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Santa Maria

Price found within the past 48 hours. Click for updated prices.
Oro Verde Machala
Oro Verde Manta
Hotel Rio Guayas
Luxury Suites Riverfront GYE
Santa Lucia Suites - Barranco

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria

Santa Maria Hotel Deals

Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111, Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $142 per night from Aug 23 to Aug 24
CA $142
CA $160 total
Aug 23 - Aug 24
8.6/10 Excellent! (754 reviews)
"Amazing experience."

Reviewed on Aug. 6, 2025

Hilton Colon Guayaquil
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Fully refundableReserve now, pay when you stay
The price is CA $131 per night from Aug 23 to Aug 24
CA $131
CA $148 total
Aug 23 - Aug 24
9.4/10 Exceptional! (1,006 reviews)
"Excellent!"

Reviewed on Aug. 15, 2025

Oro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
Fully refundable
The price is CA $122 per night from Aug 23 to Aug 24
CA $122
CA $137 total
Aug 23 - Aug 24
9.2/10 Wonderful! (1,001 reviews)
"Wow! The most elevated Holiday Inn I've ever seen. So impressed by the service, amenities, restaurant, and staff."

Reviewed on Aug. 13, 2025

Holiday Inn Guayaquil Airport by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria vacation package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting CA $1,075. When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1,000,000 hotels worldwide, your Santa Maria vacation package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream vacation in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favorites.
How far in advance should I book my Santa Maria vacation?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your vacation time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia vacation package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria vacation package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Discover the most popular places to visit in Santa Maria

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.