
Santa Isabel Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $1,096 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Santa Isabel Vacation Deals
Price found within the past 48 hours. Click for updated prices.

Villa Botero By Casa Mojito B&B
Price was CA $1,936, price is now CA $1,296 per person
CA $1,296
per person
Jun 2 - Jun 9
found 11 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
9.8/10 Exceptional! (64 reviews)
excellent breakfast every day and varied menu. nice room, had a a fridge and coffee maker, sitting area and very clean pool. walkable to beach and few restaurants - beach was very nice.
Reviewed on Mar 22, 2026

Hotel Plaza Herrera
Casco Viejo
Price was CA $3,193, price is now CA $1,836 per person
CA $1,836
per person
May 2 - May 9
found 6 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
9.8/10 Exceptional! (26 reviews)
Internet was good. Suite was spacious. Shower and clothing closet on a seperate floor from bedroom. Ceiling fan was quiet and finctioning. A/C also quiet and functioning. Deck fan operates on a chain that was to short. Hammock on the deck takes alot of space where some decent seating and a small table might be. Great view of the park and street activity. Location is not know to Uber. Early morning coffee is available. Paid for morning breakfast with room online ... used 1 of 2 breakfasts, no credit offered. Breakfast quality is reasonable and tasted good. Staff are probably best asset at this property. They try very hard to make guests welcome amd comfortable. I did not feel like was being worked for an expected tip at all.
Reviewed on Mar 24, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $3,263, price is now CA $2,020 per person
CA $2,020
per person
May 10 - May 17
found 1 day ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,000 reviews)
Great breakfast, outstanding location, lovely property.
Reviewed on Mar 29, 2026

Megapolis Hotel Panamá
San Francisco
Price was CA $2,543, price is now CA $1,707 per person
CA $1,707
per person
May 10 - May 17
found 1 day ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
8.4/10 Very Good! (1,448 reviews)
Breakfast was nice but limited on some fruit options- i expected a little more in my room for the price.
Reviewed on Mar 29, 2026

Hotel Riu Plaza Panama
Bella Vista
Price was CA $2,045, price is now CA $1,417 per person
CA $1,417
per person
May 10 - May 17
found 1 day ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (5,100 reviews)
The best breakfast buffet ever. The choices were plentiful and varied for everyone
Reviewed on Mar 29, 2026
Santa Isabel Hotel Deals

Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island Narganá Guna Yala
10/10 Exceptional! (1 review)
Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door.
Reviewed on Mar 15, 2026

Cocoloco - Catamaran Lagoon 52F SAN BLAS
El Porvenir Narganá Guna Yala
Fully refundableReserve now, pay when you stay
The price is CA $2,715 per night from Apr 7 to Apr 8
CA $2,715
CA $2,999 total
Apr 7 - Apr 8
includes taxes & fees

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.







