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Top Santa Isabel Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Riande Aeropuerto Hotel & Casino

CA $1,276

per person

Aug 5 - Aug 12

found 13 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

8.4/10 Very good! (1,813 reviews)

I would’ve given this a perfect rating but the shuttle had me waiting for over an hour at the airport and frustrated me to the point of grabbing an Uber.

Reviewed on Jun 27, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

CA $1,594

per person

Aug 5 - Aug 12

found 13 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

9.2/10 Wonderful! (1,004 reviews)

Got in on a red eye. Wouldn’t let us check into a room until 3pm unless we wanted to pay for an extra night. The rooms surrounding the lounge/dining area are loud. There is someone playing music from 7am throughout the entire day until late evening. The rooms in the back were quieter. The food was good. Breakfast buffet also really good.

Reviewed on Jun 26, 2026

Megapolis Hotel Panamá

San Francisco

CA $1,425

per person

Aug 5 - Aug 12

found 13 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

8.4/10 Very good! (1,567 reviews)

La atención, limpieza y el mall, todo muy bueno

Reviewed on Jun 28, 2026

Casa Mallet by Wynwood House

Casco Viejo

CA $2,052

per person

Jul 30 - Aug 6

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

9.8/10 Exceptional! (27 reviews)

In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

Casa Lefevre By Wynwood House

Casco Viejo

CA $1,809

per person

Jul 30 - Aug 6

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

9.6/10 Exceptional! (15 reviews)

If you want to explore Casco Viejo, the location does not get any better than this. The balcony faces Cathedral Plaza and is a quick walk to many galleries, restaurants and clubs. The apartment I was in had lots of charm and a great use of space. The check in and check out process was super easy. Also, the Wynwood team is always available on WhatsApp if there are any issues or if you need anything.

Reviewed on May 19, 2026

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Santa Isabel Hotel Deals

Cocoloco - Catamaran Lagoon 52F SAN BLAS

El Porvenir Narganá Guna Yala

Fully refundableReserve now, pay when you stay

CA $2,773

CA $3,063 total

Jul 2 - Jul 3

includes taxes & fees

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala

10/10 Exceptional! (1 review)

"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door."

Reviewed on Mar 15, 2026

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Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala

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See all 39 properties in Santa Isabel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.