Title: Book The Best Hotels in Santa Isabel for 2025 from CA $261 - Competitive Prices - Expedia.ca [Vacation Rentals in Santa Isabel](https://expedia.ca/Santa-Isabel-Vacation-Rentals.d6203540.Travel-Guide-VacationRentals)[Santa Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel.d6203540.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.ca/Santa-Isabel.d6203540.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel from CA $261 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Isabel Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Col%C3%B3n%2C+Panama®ionId=6203540&latLong=9.539417%2C-79.195937&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=OCEAN_VIEW) House­boat [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Col%C3%B3n%2C+Panama®ionId=6203540&latLong=9.539417%2C-79.195937&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&lodging=HOUSE_BOAT) ## Check prices for these dates Tonight [Nov 12 - Nov 13](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 13 - Nov 14](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-11-13&endDate=2025-11-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 44 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Aerial view](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/1370ba19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/587acb7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/519a6b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Paradise Private Cabins on Shipwreck Island - meals included Narganá CA $237 CA $261 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information) ![Panoramic Cabin, Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/7708eca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/w2878h1920x0y0-df17b8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/caaaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Narganá CA $264 CA $290 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/10dee59f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/dda30ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/eb4eaf61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/ec710209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabins in Asserya Island - San Blas paradise - meals included Narganá [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Aroma-Island.h37744686.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/8fa7ada5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/1f4d85cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Cabin](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/f71dc449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Shared Dormitory](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/f8b34eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabins on paradise San Blas island Narganá [](https://www.expedia.ca/Carti-Hotels-Cabins-In-Tuba-Senika-Island.h37822583.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/1b4156f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/a3e9a150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/5ebfc967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/7fd698a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cocoloco - Catamaran Lagoon 52F SAN BLAS Narganá CA $2,755 CA $3,047 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/9e5e20c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/4e2f141d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Bungalow](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/c36bcffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/w576h935x0y0-5a1d7985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Trips Guna Yala Narganá CA $137 CA $329 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Nargana-Hotels-Trips-Guna-Yala.h103726734.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27®ionId=6203540&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d6203540.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d6203540.Travel-Guide-Hotels) ## More cheap stays in Santa Isabel ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Diablo Island, Narganá, Guna Yala CA $264 CA $290 total Nov 13 - Nov 14 includes taxes & fees [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information) ![ San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### San Blas Paradise Private Cabins on Shipwreck Island - meals included Perro Island, Narganá, Guna Yala CA $237 CA $261 total Nov 13 - Nov 14 includes taxes & fees [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information) ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Private Over the Water Cabin on San Blas Island 9.542876, -78.899058, Narganá, San Blas [Get rates](https://expedia.ca/Hotel-Search?startDate=26%2F11%2F2025&endDate=27%2F11%2F2025&selected=37715808&PinnedHotelID=37715808&HadPinnedHotel=true®ionId=6203540) 7/10 Good! (6 reviews) [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![Cabins in Asserya Island - San Blas paradise - meals included](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/10dee59f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cabins in Asserya Island - San Blas paradise - meals included Aroma Island (Isla Anzuelo), Narganá, Guna Yala [Get rates](https://expedia.ca/Hotel-Search?startDate=26%2F11%2F2025&endDate=27%2F11%2F2025&selected=37744686&PinnedHotelID=37744686&HadPinnedHotel=true®ionId=6203540) [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Aroma-Island.h37744686.Hotel-Information) ![ Paradise Over the Water Cabins in San Blas](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/fe0394dd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Paradise Over the Water Cabins in San Blas G4V2 48, Narganá, Guna Yala [Get rates](https://expedia.ca/Hotel-Search?startDate=26%2F11%2F2025&endDate=27%2F11%2F2025&selected=46948372&PinnedHotelID=46948372&HadPinnedHotel=true®ionId=6203540) [](https://expedia.ca/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information) ![Private wood Cabins on San Blas island - private bathroom](https://images.trvl-media.com/lodging/38000000/37750000/37743100/37743019/b9c5df53_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Private wood Cabins on San Blas island - private bathroom Wailidup Island, Narganá, Guna Yala [Get rates](https://expedia.ca/Hotel-Search?startDate=26%2F11%2F2025&endDate=27%2F11%2F2025&selected=37743019&PinnedHotelID=37743019&HadPinnedHotel=true®ionId=6203540) [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Wailidup-Island.h37743019.Hotel-Information) ## Recent reviews of Santa Isabel hotels ![Private Over the Water Cabin on San Blas Island](//images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg) ### Private Over the Water Cabin on San Blas Island 5/5 Excellent "Very nice. And I liked the food " A verified traveller stayed at Private Over the Water Cabin on San Blas Island Posted 3 months ago [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa Isabel? > Located 21.8 mi (35.1 km) from the heart of Santa Isabel, [San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information) is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are [Private Ocean-Front Cabin with private bathroom on San Blas Island](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information) and [Cocoloco - Catamaran Lagoon 52F SAN BLAS](https://www.expedia.ca/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information). See all available [top hotels](https://www.expedia.ca/Hotel-Search?regionId=6203540), or [vacation rentals in Santa Isabel](https://www.expedia.ca/Santa-Isabel-Vacation-Rentals.d6203540.Travel-Guide-VacationRentals). ### What are some of the best vacation home rentals that Santa Isabel has to offer? > [Caribbean Paradise - Beachfront Getaway](https://www.expedia.ca/Caribbean-Paradise-Beachfront-Getaway.h104131479.Hotel-Information): This vacation home rental outside of Santa Isabel comes with air-conditioning so you can feel at home during your trip. See all [vacation rentals in Santa Isabel](https://www.expedia.ca/Santa-Isabel-Vacation-Rentals.d6203540.Travel-Guide-VacationRentals). ### If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund? > Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=6203540&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santa Isabel. ### What is staying in Santa Isabel like? > Visitors can enjoy all that Santa Isabel has to offer including its parks. There are 44 hotels and other accommodations in the surrounding area. Find out more about [Santa Isabel](https://www.expedia.ca/Santa-Isabel.dx6203540). ### What are the top places to visit in Santa Isabel? > Places to visit in the wider area include [Chagres National Park](https://www.expedia.ca/Chagres-National-Park-Panama.d6252818.Vacation-Attraction), [Museum](https://www.expedia.ca/Museum-Carti.d553248621532964865.Vacation-Attraction), and [Porvenir Museum](https://www.expedia.ca/Porvenir-Museum-Guna-Yala.d553248621532964866.Vacation-Attraction). Check out what more to see and do in Expedia's [Santa Isabel guide](https://www.expedia.ca/Santa-Isabel.dx6203540). ### What's the seasonal weather like in Santa Isabel? > The hottest months are usually June and September with an average temp of 80°F, while the coldest months are February and March with an average of 78°F. The rainiest months in Santa Isabel are October, August, July, and November, with each month seeing an average of 12 inches of rainfall. ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [La Guaira Hotels](https://www.expedia.ca/La-Guaira-Hotels.d3000439511.Travel-Guide-Hotels) - [Nombre de Dios Hotels](https://www.expedia.ca/Nombre-De-Dios-Hotels.d3000462548.Travel-Guide-Hotels) - [Palenque Hotels](https://www.expedia.ca/Palenque-Hotels.d553248623282267036.Travel-Guide-Hotels) - [Playa Chiquita Hotels](https://www.expedia.ca/Playa-Chiquita-Hotels.d553248635975847835.Travel-Guide-Hotels) - [Palenque Vacations](https://www.expedia.ca/Palenque.d553248623282267036.Destination-Travel-Guides) - [Car rental Miramar](https://www.expedia.ca/Car-Rentals-In-Miramar.d553248623282266307.Car-Rental-Guide) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)