A tropical island with a beach, clear turquoise waters, and lush greenery.

Find hotels in Santa Isabel from CA $288

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Tonight
Aug 13 - Aug 14
Tomorrow
Aug 14 - Aug 15
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

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Our top choices for Santa Isabel hotels

1. Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
Narganá
United States
Ryan
CA $262
CA $288 total
includes taxes & fees
Aug 20 - Aug 21
Private Ocean-Front Cabin with private bathroom on San Blas Island

2. Cabins on paradise San Blas island

Cabins on paradise San Blas island
Narganá
CA $375
CA $412 total
includes taxes & fees
Aug 14 - Aug 15
Cabins on paradise San Blas island

3. Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
Narganá
CA $2,752
CA $3,037 total
includes taxes & fees
Sep 13 - Sep 14
Cocoloco - Catamaran Lagoon 52F SAN BLAS
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Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkelling. Hike through lush rainforest trails to spot colourful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

See all hotels in Santa Isabel
A tropical island with a beach, clear turquoise waters, and lush greenery.

Top Santa Isabel Hotel Reviews

Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

10/10 Excellent
"the view is beautiful! We were taken care of well."
Mirelys 5-night trip
Posted 3 weeks ago
Caribbean getaway: beach cottage just on the sand
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 6 months ago
Private Ocean-Front Cabin with private bathroom on San Blas Island
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10/10 Excellent
"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful host, Leticia, who went above and beyond helpful. "
Dennis Or Trish H. 6-night trip
Posted 8 months ago
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

More cheap stays in Santa Isabel

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala
CA $262
CA $288 total
Aug 20 - Aug 21
includes taxes & fees
10/10 Exceptional! (1 review)
Private Ocean-Front Cabin with private bathroom on San Blas Island
Cabins on paradise San Blas island

Cabins on paradise San Blas island

9.587566, -78.879820 Narganá San Blas
CA $375
CA $412 total
Aug 14 - Aug 15
includes taxes & fees
Cabins on paradise San Blas island
Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala
Get ratesPrivate wood Cabins on San Blas island - private bathroom
 Paradise Over the Water Cabins in San Blas

Paradise Over the Water Cabins in San Blas

G4V2 48 Narganá Guna Yala
Get rates
6/10 (1 review)
Paradise Over the Water Cabins in San Blas
Trips Guna Yala

Trips Guna Yala

Urgandi, Mamardub Narganá Guna Yala
Get ratesTrips Guna Yala
Hotel El Porvenir

Hotel El Porvenir

Isla Porvenir Narganá Guna Yala
Get ratesHotel El Porvenir

Frequently asked questions

What is the best area to stay in Santa Isabel?
The best area to stay in Santa Isabel, Colón, Panama, is along the coastal stretch near the town centre and extending towards properties with private beach access.This area offers direct access to the Caribbean Sea and is known for its serene environment. You'll find a selection of accommodations, from boutique hotels to more secluded resorts, typically located just off the main coastal road, providing easy access while maintaining a sense of privacy.Couples often find this area ideal for a romantic getaway. The focus here is on relaxation and enjoying the natural beauty, with opportunities for quiet walks along the beach, swimming in the clear waters, and enjoying meals with ocean views. Some establishments offer private balconies overlooking the sea, superb for morning coffee or evening drinks.For those looking for a luxurious and secluded experience, the properties further along the coast, offering private beach access and extensive grounds, are an excellent choice.
When is the best time to go to Santa Isabel?
The best time to visit Santa Isabel, Colón, Panama, is during the dry season, which typically runs from mid-December to mid-April. This period offers the most consistent sunshine and pleasant weather for exploring the area.During these months, you'll experience less rainfall and lower humidity, making outdoor activities like beach visits, jungle treks, and boat trips far more enjoyable. The calm waters are also ideal for snorkelling and diving, allowing for clear views of the marine life.Couples looking for a relaxing escape will find this time particularly appealing. The consistent good weather means you can confidently plan days by the coast or explore the natural beauty without concerns about sudden downpours. It's superb for enjoying the pristine beaches and the serene atmosphere.Travellers interested in exploring the natural parks and engaging in outdoor adventures will also benefit from the dry season. The trails are more accessible, and wildlife spotting is often easier when the weather is clear.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Isabel.
How much is the nightly rate at a Santa Isabel hotel?
Prices for hotels in Santa Isabel often vary, but you can find a great deal from CA $288 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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