Title: Santa Ana Vacation Packages | Holiday Packages & Trips 2026/2027 from  Expedia.ca

[Hotels in Santa Ana](https://expedia.ca/Santa-Ana-Panama-City-Hotels.0-n553248623199107606-0.Travel-Guide-Filter-Hotels)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)

![](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santa Ana Vacation Packages

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to CA $1,096 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

#### Your Santa Ana Vacation

From its sunny weather to its diversity and beyond, there's loads to love about Santa Ana. Discover the wonders of this awesome city with a Santa Ana vacation package that's made for you. Eager to explore your new surroundings? [Miraflores Locks](https://www.expedia.ca/Miraflores-Locks-Panama-City.d6078505.Vacation-Attraction), [Bridge of the Americas](https://www.expedia.ca/Bridge-Of-The-Americas-Panama-City.d6078487.Vacation-Attraction) and [Metropolitan Cathedral of Panama](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Casco-Viejo.d6078477.Vacation-Attraction) are among the best places to visit during a trip to Santa Ana. Whoever you're traveling with and whatever you want to spend, your dream Santa Ana vacation is just clicks away with Expedia.

## Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Santa Ana](https://expedia.ca/Santa-Ana.dx553248623199107606)

![View of the Panama City Old Town](https://images.trvl-media.com/place/6285189/5de33a79-734e-444d-a7f7-18272ceb73c2.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Casco Viejo

4/5(32 area reviews)

 Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area. 

[Find hotel + flight trips in Casco Viejo](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Casco%20Viejo&DestID=6285189&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Bella Vista](https://images.trvl-media.com/place/2897/62672ebb-ab68-4df6-9850-2c73cf428908.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Bella Vista

1 out of top 10 points of interest in this area

 Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. 

[Find hotel + flight trips in Bella Vista](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Bella%20Vista&DestID=3000663485&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Panama City Old Town streets and buildings](https://images.trvl-media.com/place/6285972/af7e9b24-0964-44fc-86b9-7efe328f4d40.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### El Cangrejo

4/5(66 area reviews)

 The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip. 

[Find hotel + flight trips in El Cangrejo](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=El%20Cangrejo&DestID=6285972&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![The Bridge of the Americas in summer, Panama City](https://images.trvl-media.com/place/553248623199112076/b14d4c65-cc25-49b4-aad3-c708d5b994fc.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Francisco

1 out of top 10 points of interest in this area

 San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. 

[Find hotel + flight trips in San Francisco](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Francisco&DestID=553248623199112076&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America](https://images.trvl-media.com/place/829297728598073344/b153dfc8-01d6-40ec-9e98-642d0f1b8062.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Felipe

 If you're spending some time in San Felipe, Independence Square and National Theater are top sights worth seeing. 

[Find hotel + flight trips in San Felipe](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Felipe&DestID=829297728598073344&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Santa Ana Hotel Deals

![Casco View Apartments](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378_y.jpg?impolicy=resizecrop&rw=340&ch=150)

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Casco View Apartments

C. 16 Oeste Panama City Provincia de Panamá

CA $127

CA $182 total

Apr 9 - Apr 10

includes taxes & fees

9/10 Wonderful! (85 reviews)

yes there was laundryroom, iron and nice pool. the stay was very good

Reviewed on Mar 30, 2026

[](https://expedia.ca/Hotel-Search?startDate=09%2F04%2F2026&endDate=10%2F04%2F2026&selected=102803573&PinnedHotelID=102803573&HadPinnedHotel=true&regionId=553248623199107606)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

CA $202

CA $222 total

May 5 - May 6

includes taxes & fees

9/10 Wonderful! (5,205 reviews)

Great

Reviewed on Apr 5, 2026

[](https://expedia.ca/Hotel-Search?startDate=05%2F05%2F2026&endDate=06%2F05%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true&regionId=553248623199107606)

![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

CA $177

CA $204 total

Apr 28 - Apr 29

includes taxes & fees

8.6/10 Excellent! (2,493 reviews)

Poor at 6am

Reviewed on Apr 4, 2026

[](https://expedia.ca/Hotel-Search?startDate=28%2F04%2F2026&endDate=29%2F04%2F2026&selected=8836117&PinnedHotelID=8836117&HadPinnedHotel=true&regionId=553248623199107606)

[See all 1,529 properties in Santa Ana](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=06%2F04%2F2026&endDate=07%2F04%2F2026&regionId=553248623199107606)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Family Vacations

[](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

## Frequently asked questions

### How much does a Santa Ana vacation package cost?

### How do I get a cheap travel package to Santa Ana?

### Where should I stay in Santa Ana?

### What are the top hotels in Santa Ana?

### How far in advance should I book my Santa Ana vacation?

### What does an Expedia Santa Ana travel package include?

### What should I know before booking a Santa Ana travel package?

### Can I choose my airline with a Santa Ana Expedia vacation package?

### If I'm not able to travel, can I cancel my Santa Ana vacation package?

### Discover the most popular places to visit in Santa Ana

![Multiplaza Pacific Mall](https://images.trvl-media.com/place/2897/ad002056-eab0-46bc-8398-21350ee7da55.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area. 

[](https://expedia.ca/Multiplaza-Pacific-Mall-San-Francisco.d6158227.Vacation-Attraction)

![Panama City night skyline](https://images.trvl-media.com/place/553248623453290531/4749914b-de3c-4565-87b6-0c470bc2cde8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting. 

[](https://expedia.ca/Avenida-Balboa-Calidonia.d553248623453290531.Vacation-Attraction)

![Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.](https://images.trvl-media.com/place/6245970/dcde0ea1-f452-4e6e-a661-261f8d2489db.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Cinta Costera

After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside. 

[](https://expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction)

### Things to do

![Panama City: Poin Glass Observation Deck Ticket with VR Tour](https://mediaim.expedia.com/localexpert/48083083/e4ea59a3-da5a-4416-9a33-99eff95fee6d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Panama City: Poin Glass Observation Deck Ticket with VR Tour

CA $44

per adult

**100%** of travellers recommend

[](https://expedia.ca/things-to-do/panama-city-poin-glass-observation-deck-ticket-with-vr-tour.a48083083.activity-details)

![All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City](https://mediaim.expedia.com/localexpert/5092538/f9052c60-b5f8-49a3-9993-6541bfdd54d6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

CA $136

per adult

**96%** of travellers recommend

[](https://expedia.ca/things-to-do/all-inclusive-8-hour-catamaran-tour-to-isla-taboga-from-panama-city.a5092538.activity-details)

![Great to do it alone or accompanied.](https://mediaim.expedia.com/localexpert/49805810/eaad6101-7755-46c7-9e36-9b17db303c99.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Zipline in Panama City.

CA $51

per adult

**100%** of travellers recommend

[](https://expedia.ca/things-to-do/zipline-in-panama-city.a49805810.activity-details)

[See all activities in Panama City](https://expedia.ca/things-to-do/search?rid=553248623199107606)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.