Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
CA $51
per adult
100% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
CA $140
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
CA $94
per adult
96% of travellers recommend
Panama City: Embera Native Village & Waterfall Tour & Lunch
CA $92
per adult
From Panama City: San Blas Islands Tour with Island Hopping
CA $205
per adult
98% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
CA $45
per adult
100% of travellers recommend
Santa Ana Hotel Deals
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
The price is CA $73 per night from Nov 10 to Nov 11
CA $73
CA $80 total
Nov 10 - Nov 11
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
7.6/10 Good! (31 reviews)
"El lugar es acorde a lo q se paga, esta donde termina el casco viejo y empieza un barrio feo"
Reviewed on Nov 5, 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
The price is CA $117 per night from Nov 11 to Nov 12
CA $117
CA $171 total
Nov 11 - Nov 12
includes taxes & fees
Book a stay at this business-friendly condo in Panama City. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Popular attractions Albrook Shopping ...
9/10 Wonderful! (114 reviews)
"The staff was very friendly and helpful which made our stay very pleasant and enjoyable."
Reviewed on Oct 31, 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is CA $184 per night from Dec 1 to Dec 2
CA $184
CA $203 total
Dec 1 - Dec 2
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (6,180 reviews)
"Todo excelente, lo unico que no me gustó fué que me cobraron por el estacionamiento"
Reviewed on Nov 6, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
The price is CA $163 per night from Dec 6 to Dec 7
CA $163
CA $179 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,011 reviews)
"Excelente atención y ambiente full recomendado"
Reviewed on Nov 5, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is CA $183 per night from Nov 8 to Nov 9
CA $183
CA $225 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
The price is CA $367 per night from Dec 1 to Dec 2
CA $367
CA $367 total
Dec 1 - Dec 2
includes taxes & fees
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
7.8/10 Good! (1,123 reviews)
"En general la comida estaba buena, pero sí se notó que repitieron mucho la comida, que la oferta novedosa era muy limitada (la noche mexicana era un taco de carne con queso y uno de adobado), los eventos en sí mismos fueron planos, en el caso de estas fiestas patrias estaba claro que era para los ..."
Reviewed on Nov 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
