San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo
Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Popular places to visit

Things to do


San Francisco Hotel Deals

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is CA $184 per night from Apr 3 to Apr 4
CA $184
CA $202 total
Apr 3 - Apr 4
includes taxes & fees
Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,009 reviews)
Breakfast was great , clean room and staff was nice

Reviewed on Mar 20, 2026

Sheraton Grand Panama
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is CA $131 per night from Mar 28 to Mar 29
CA $131
CA $144 total
Mar 28 - Mar 29
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,153 reviews)
Yes everything was perfect 10/10

Reviewed on Mar 20, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is CA $325 per night from Apr 5 to Apr 6
CA $325
CA $358 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,001 reviews)
Fantastic pool. Great food, I'd recommend the fish and chips. Best I've ever had. Great bar. Friendly staff.

Reviewed on Mar 19, 2026

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is CA $139 per night from Apr 18 to Apr 19
CA $139
CA $153 total
Apr 18 - Apr 19
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,005 reviews)
Clean room Excellent , but the small pool need removing the abundant mold on the walls and edges of the pools is very visible and unpleasant in the small area.

Reviewed on Mar 22, 2026

Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is CA $216 per night from Apr 12 to Apr 13
CA $216
CA $238 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,002 reviews)
The hotel on a whole is very clean. I loved that everyday our towels were changed. Also, as you enter the hotel you can smell the freshness. I enjoyed the clean space every day.

Reviewed on Mar 20, 2026

Las Americas Golden Tower Panama
Aloft Panama

Aloft Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is CA $163 per night from Apr 4 to Apr 5
CA $163
CA $179 total
Apr 4 - Apr 5
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (994 reviews)
TODO BIEN

Reviewed on Mar 16, 2026

Aloft Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

4/5(14 area reviews)

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants, and casinos, Punta Pacifica is a sought-after destination for many travelers visiting Panama City. If you want to see some sights in the area, check out Pacific Center or Avenida Balboa.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

4/5(46 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


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