Title: 10 Best Hotels in Santa Ana, Panama City for 2026 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Plaza Santa Ana, Panama Casco Viejo](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Ana, Panama City - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/132a0077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/83a1ee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) Santa Ana 7.6/10 Good (55) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) David CA $30 CA $34 total includes taxes & fees Jan 6 - Jan 7, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duplex | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.2/10 Wonderful (56) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris CA $113 CA $125 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, free WiFi](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/6401edce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) Santa Ana 6.6/10 (182) "Fantastic customer service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) OLGA [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/a4e5c85a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/67d4e119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, 1 Double Bed | Bathroom](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/b05b8020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/6917aaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ART CASCO The Hotel [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) Santa Ana 6.0/10 (11) "Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eldris [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/d5acebbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/bc995ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA CA $98 CA $146 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Room, Multiple Bedrooms, Accessible, Smoking | Pool](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/b9369105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Fitness studio](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-8b7f1fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Living room](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-35b02ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/141773b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room-sofa Bed Stay Rooftop Pool & Gym, A [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) Santa Ana 2.0/10 (1) "You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cristian Camilo Betancur CA $194 CA $215 total includes taxes & fees Jan 15 - Jan 16, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/1875cd38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 12 per person)](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/533863fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/22468caf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 7.4/10 Good (271) "Hotel staff and rooms were good , great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cornelly CA $116 CA $128 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/6010dc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/3873c049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) 21.1 km from Santa Ana 8.4/10 Very good (2333) "Great breakfast was included and the airport shuttle was conveniently located " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrienne CA $150 CA $165 total includes taxes & fees Jan 15 - Jan 16, 2026 [](https://www.expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/febf3b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/c164ba0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/d1a4e6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/c8d2e545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ORHO HOTEL BOUTIQUE PANAMA Airport [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) 20.5 km from Santa Ana 9.0/10 Wonderful (39) "It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarissa CA $164 CA $213 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/04f50e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) 19.8 km from Santa Ana 8.6/10 Excellent (1847) "Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marty CA $171 CA $188 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/e7c38de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/e7f3d07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/70833eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/b76cac34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall [](https://www.expedia.ca/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) 14.6 km from Santa Ana 8.8/10 Excellent (1004) "The hotel is conveniently close to the airport and shopping centres. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha CA $150 CA $165 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Suite, 1 Bedroom, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz, 12.7 km from Santa Ana 9.6/10 Exceptional (644) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose CA $307 CA $337 total includes taxes & fees Jan 25 - Jan 26, 2026 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f6eaf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este, 10.2 km from Santa Ana 9.4/10 Exceptional (168) "Was a great buy. Beautiful views and spacious rooms. Great amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesley CA $113 CA $188 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2aa9e1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/e8d59b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8d6ae106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8ad18c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Panama [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) Costa del Este, 9.4 km from Santa Ana 9.0/10 Wonderful (311) "Great hotel and services" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pedro CA $293 CA $322 total includes taxes & fees Jan 10 - Jan 11, 2026 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/1f8c9ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco, 5.7 km from Santa Ana 8.6/10 Excellent (996) "Was amazing food was delicious and stay was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $183 CA $202 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/4a3f7176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/7d818005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/a87f2f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Panama [](https://www.expedia.ca/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) San Francisco, 5.7 km from Santa Ana 8.8/10 Excellent (896) "Great staff..warm and welcoming...enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alystra Marissa Arjoon CA $162 CA $179 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/11d7a719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/9a4bbb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/22b0bcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/0babe4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) Punta Pacifica, 4.3 km from Santa Ana 9.0/10 Wonderful (1002) "Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarran CA $423 CA $465 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/803aefa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/f3139092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/94455d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) San Francisco, 5.1 km from Santa Ana 9.6/10 Exceptional (1126) "The hotel is in a great location in Panama. Great amenities excellent breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $134 CA $147 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/5bdfb47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/db15307b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/2b453483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Ocean View](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/8b731fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Panama City [](https://www.expedia.ca/Panama-City-Hotels-Residence-Inn-By-Marriott-Panama-City.h38742070.Hotel-Information) Punta Paitilla, 4 km from Santa Ana 9.0/10 Wonderful (542) "It's location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $220 CA $242 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Residence-Inn-By-Marriott-Panama-City.h38742070.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/3db8be94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/5b3a3c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel [](https://www.expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) Punta Paitilla, 3.4 km from Santa Ana 9.4/10 Exceptional (2138) "Great location of the hotel with a lovely breakfast and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) fouad CA $148 CA $162 total includes taxes & fees Jan 16 - Jan 17, 2026 [](https://www.expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Felipe - San Francisco [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d5ab8e549e1cfa831dcb33b7e1b0352d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/919b43d85bf36a400b3c07d30881f725.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/de251296a0096f0bf5fd9914c545600d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/a8f0f1d663e33ab4f81206a124826dcd.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=829297728598073344) ![San Felipe map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### San Felipe If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=829297728598073344) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) ## Top Santa Ana Hotel Reviews ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Everything stood out " [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good" [](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Experiencia maravillosa buena atención " [](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "I had a wonderful stay at this hotel and highly recommend it. The location is excellent and very central, very close to the Jewish community, including a synagogue and Chabad. Everything is within walking distance — a pleasant neighborhood with a park, supermarket, pharmacy, and a shopping mall. The rooms were very clean and well maintained, with a lovely view. The breakfast was full and generous, with a wide variety of options — nothing was missing. The internet connection was strong and reliable. The service was available 24/7, and the staff was helpful and professional. I would definitely stay here again. " [](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Beautiful hotel. Comfortable and well-appointed room, delicious breakfast, helpful staff. Recommended." [](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Beautiful and luxurious " [](https://expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "No worries. Outstanding in every aspects. Room, food, personnel, pool, location. " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Great place and location, excellent food choices! " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Yes" [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Amador Hotels ](https://www.expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels ](https://www.expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - 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[Flights from Tambor (TMU) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/tmu/pac/tambor-to-panama-city) - [Flights from Edmonton (YEG) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yeg/pac/edmonton-to-panama-city) - [Flights from Halifax (YHZ) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yhz/pac/halifax-to-panama-city) - [Flights from Kelowna (YLW) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/ylw/pac/kelowna-to-panama-city) - [Flights from Ottawa (YOW) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yow/pac/ottawa-to-panama-city) - [Flights from Montreal (YUL) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yul/pac/montreal-to-panama-city) - [Flights from Vancouver (YVR) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yvr/pac/vancouver-to-panama-city) - [Flights from Saskatoon (YXE) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yxe/pac/saskatoon-to-panama-city) - [Flights from Calgary (YYC) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yyc/pac/calgary-to-panama-city) - [Flights from Toronto (YYZ) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Cinta Costera ](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas ](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [Maracana Stadium ](https://www.expedia.ca/Maracana-Stadium-El-Chorrillo.d553248621562725885.Vacation-Attraction) - [Visit Balboa ](https://www.expedia.ca/Panama-City-Balboa.dx6323179) - [Visit Calidonia ](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Casco Viejo ](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu ](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Chorrillo ](https://www.expedia.ca/Panama-City-El-Chorrillo.dx553248623199107689) - [Panamá Province Vacations ](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province ](https://www.expedia.ca/Panama-Province.dx6246281) - [Car rentals near Albrook Shopping Mall ](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Balboa ](https://www.expedia.ca/Car-Rentals-In-Balboa.d6323179.Car-Rental-Guide) - [Panamá Province Vacation Rentals ](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)