Title: 10 Best Hotels in Santa Ana, Panama City for 2025 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Ana, Panama City ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Ana Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&lodging=APART_HOTEL) Spa [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&amenities=SPA_ON_SITE) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&travelerType=family_friendly) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&amenities=OCEAN_VIEW) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&amenities=PETS) Condo [](https://www.expedia.ca/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-13&d1=2025-10-13&endDate=2025-10-15&d2=2025-10-15&lodging=CONDO) ## Check prices for these dates Tonight [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-09-29&endDate=2025-09-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Santa Ana hotels and places to stay ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments Santa Ana 9.4/10 Exceptional (47) "Great stay, would recommend." CA $101 CA $111 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/92156b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, free WiFi](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/6401edce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República Santa Ana 6.6/10 (176) "Fantastic customer service" CA $33 CA $38 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/a4e5c85a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/67d4e119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/6917aaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, 1 Double Bed | Bathroom](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/b05b8020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ART CASCO The Hotel Santa Ana 6.6/10 (8) "Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best" CA $51 CA $56 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/83a1ee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/132a0077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra Santa Ana 7.4/10 Good (53) "Helpful staff, secure, close to sights" CA $28 CA $32 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Single Room](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/df04c1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Triple Room | Bathroom](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/fc44afbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Quadruple Room, 2 Double Beds](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/28308f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/cd9ccafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riazor Santa Ana 3.8/10 (11) "Rough neighborhood " CA $35 CA $39 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Panama-City-Hotels-JOSE-PEREZ-PINAL.h89148227.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/bc995ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09) | Private kitchen](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/f1ebeb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House Santa Ana 7.0/10 Good (14) "Great hotel. Very close to Casco viejo" CA $60 CA $94 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Room, Multiple Bedrooms, Accessible, Smoking | Pool](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/b9369105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/141773b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Living room](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-35b02ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2042h1548x6y4-9f255786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room-sofa Bed Stay Rooftop Pool & Gym, A Santa Ana 2.0/10 (1) "You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money" CA $197 CA $218 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) ![Apartment | Terrace/patio](https://images.trvl-media.com/lodging/102000000/101290000/101284400/101284317/87e9de43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen](https://images.trvl-media.com/lodging/102000000/101290000/101284400/101284317/578388cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/102000000/101290000/101284400/101284317/9f76c377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/102000000/101290000/101284400/101284317/71786113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Quijano 06 By Wynwood House Santa Ana 9.0/10 Wonderful (4) "The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you... CA $70 CA $123 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Panama-City-Hotels-Casa-Quijano-06-By-Wynwood-House.h101284317.Hotel-Information) ![Apartment](https://images.trvl-media.com/lodging/119000000/118040000/118039000/118038904/b5ca3965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118040000/118039000/118038904/9e1cd18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118040000/118039000/118038904/5fc3561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/119000000/118040000/118039000/118038904/658fcd85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w Charming 1BR in Santa Ana s Best Area Santa Ana CA $70 CA $127 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Panama-City-Hotels-W-Charming-1BR-In-Santa-Ana-S-Best-Area.h118038904.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/6010dc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG 21.1 km from Santa Ana 8.4/10 Very good (2255) "The staff was very nice and helpful and the place was very nice" CA $174 CA $192 total includes taxes & fees Oct 3 - Oct 4 [](https://www.expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/58d3a2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/09deaa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/w6390h4261x0y0-9ab7a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo San Felipe, 0.9 km from Santa Ana 9.0/10 Wonderful (1006) "Great staff " CA $214 CA $235 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Exclusive House | Terrace/patio](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/e71bb101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![San Felipe Junior Suite, 1 Double bed or 2 Single Beds](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/4964bad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/f174b378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive House | Living area](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/711d436d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Concordia Boutique Hotel San Felipe, 0.5 km from Santa Ana 9.4/10 Exceptional (184) "Beautiful boutique hotel. Our room was large, bed is comfortable, nice selection of pillows, large balcony. Hotel staff is friendly and helpful. I highly recommend this place." CA $243 CA $267 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/c8749fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/c95dd32a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/86d63ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 14 per person)](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/aed99723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Panamá Centro El Cangrejo, 3.5 km from Santa Ana 9.0/10 Wonderful (1018) "Place was very clean, lovely staff." CA $114 CA $125 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Panama-City-Hotels-TRYP-By-Wyndham-Panama-Centro.h5309170.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/42ee64f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 2 Double Beds](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/12f18f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Triple)](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/139e066b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/dd414168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Coral Suites El Cangrejo, 3.7 km from Santa Ana 9.0/10 Wonderful (1007) "Great location with spacious rooms " CA $97 CA $106 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Coral-Suites.h3893051.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/67639d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City)](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama Campo Alegre, 3.6 km from Santa Ana 9.0/10 Wonderful (4357) "Excellent stay!!" CA $165 CA $182 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/ae55473e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/bc945d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4e8feb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá Punta Paitilla, 3.5 km from Santa Ana 8.4/10 Very good (1103) "Great place " CA $174 CA $192 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/04f50e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino 19.8 km from Santa Ana 8.4/10 Very good (1912) "Nice hotel, close to the airport, friendly staff" CA $208 CA $229 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/d3127913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/cecfcd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/31f2cc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Principe Hotel and Suites El Cangrejo, 3.9 km from Santa Ana 9.0/10 Wonderful (1496) "Great place to stay" CA $77 CA $85 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/f988dfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/a2ab1d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/d813f542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Panama City El Cangrejo, 4.3 km from Santa Ana 9.0/10 Wonderful (1025) "The Staff were all welcoming location was very convenient I highly recommend " CA $138 CA $152 total includes taxes & fees Oct 25 - Oct 26 [](https://www.expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/7c4bef31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/675171b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/db8dd960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/14f91618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospedium Princess Hotel Panama Obarrio, 3.6 km from Santa Ana 7.6/10 Good (627) "I enjoyed my stay" CA $64 CA $71 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Francisco - Calidonia [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GpApAHQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=mIbL0U7ErAS9ivDqwvmagNSfMyo=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d5ab8e549e1cfa831dcb33b7e1b0352d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/919b43d85bf36a400b3c07d30881f725.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/de251296a0096f0bf5fd9914c545600d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/a8f0f1d663e33ab4f81206a124826dcd.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeYaEa%60Aah%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=oG-MQ0hxX1rpWwnnPw_PJqVmXHQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGzW%7D%40pIrDpFzGvJpGwFlIpFlGg%60%40%7CR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=8_zB23-SSzjkPKWLARid243P2aQ=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNgV%7BDwd%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qCjA%7D%40bCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEnD%7BBnCmAyAt%40dEb%40Nf%40e%40FaAzBkCnFfDFr%40%7B%40h%40Jr%40rIvFjFdL%60KlJfM%60SlDPbe%40eBtBlAp%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40jAImA%7DEQCXz%40VoATQdAn%40p%40lH%40zBrBf%40xBK%60AtAVf%40%7EAvAd%40jD%7ECXjAYhE%60%40%5CbBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7D%40kHgFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Af_bFXN9P57GgfSKhB3SljCaDkY=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) ![](https://mediaim.expedia.com/destination/1/ee09076776d80dd9c6cb1d4d4ba40f09.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663488) ![Calidonia map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:kavu%40%60%7DndNw%5Do%5Duq%40%7BJvIySzHnBf%40%5DxG_d%40nA%7B%40n%40%40vAwAvFlCtBnCfCmCj%40aAoBoAd%40%7D%40%7DBwK%60%40_%40h%40B%60DpDjCjGGnCcDbGzKpI%60CMz%40Zp%40nDhPjMnCDhLkE%60ADp%40fAo%40%7EDVtB%7EAhBtDv%40sF%7EPkIjFeAnBhB%5EjAxEGxAqEtAkEoBkB%3Fy%40b%40mFpH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=t-AB6vn76rJeC0pnuBbk71GWBcg=) ### Calidonia You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663488) ## Top Santa Ana Hotel Reviews ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Verry good i drove to albrook mall " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "I encourage family and friends to take a vacation to visit Panama " [](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Ramada Plaza By Wyndham Panama Punta Pacífica](//images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/803aefa9_y.jpg) ### Ramada Plaza By Wyndham Panama Punta Pacífica 10/10 Excellent "Had a great time. Staff were friendly, breakfast was good. My only issue was the absence of a bellhop. Room service daily, great view from your room and hallway. Very close to Multiplaza Mall, Burger King, Popeyes and other food establishments. Would definitely stay here again. " [](https://expedia.ca/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Crowne plaza is close and convenient to the airport, reliable free shuttle, easy checkin, nice restaurant. We stay here often" [](https://expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "The Sheraton is a large property, so the size lends itself to several dining options, a very large gym, spacious areas to hang out. WiFi coverage was excellent." [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Waldorf Astoria Panama](//images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Staff was exceptional in every area. Made me feel at home, helped me celebrate my birthday, can't thank them enough!" [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Decapolis Hotel Panama City](//images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good price , location and tasty breakfast " [](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Novotel Panama City](//images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Great location, friendly helpful staff, nice clean rooms, although lighting could be improved, but everything else was fine. Highly recommend it" [](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Free parking was nice" [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > In the heart of Panama City, [Hostal La Cigarra](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) offers an inclusive setting that combines traditional design with modern comforts, making it a great choice for budget-conscious travellers. With a customer review rating of 7.4, this hostal is situated near historical districts and shopping areas, allowing families to explore the rich culture and vibrant life of the city. Guests appreciate the complimentary in-room WiFi, making it easy to stay connected while on the go. > > > > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Ana. ### How can I save on a Santa Ana hotel booking with Expedia? > Members always get our best prices. Find our best Santa Ana hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Santa Ana hotel? > Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. 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[Flights from Toronto (YYZ) to Panama City (PAC)](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Cinta Costera](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-El-Chorrillo.d553248621562725885.Vacation-Attraction) - [Visit Balboa](https://www.expedia.ca/Panama-City-Balboa.dx6323179) - [Visit Calidonia](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Casco Viejo](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Chorrillo](https://www.expedia.ca/Panama-City-El-Chorrillo.dx553248623199107689) - [Panamá Province Vacations](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province](https://www.expedia.ca/Panama-Province.dx6246281) - [Car rentals near Albrook Shopping Mall](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Balboa](https://www.expedia.ca/Car-Rentals-In-Balboa.d6323179.Car-Rental-Guide) - [Panamá Province Vacation Rentals](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations) - Explore a world of travel with Expedia ### Hotels in top Panama City neighborhoods - [Hotels in Casco Viejo](https://expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels in Bella Vista](https://expedia.ca/Bella-Vista-Panama-City-Hotels.0-n3000663485-0.Travel-Guide-Filter-Hotels) - [Hotels in El Cangrejo](https://expedia.ca/El-Cangrejo-Panama-City-Hotels.0-n6285972-0.Travel-Guide-Filter-Hotels) - [Hotels in San Francisco](https://expedia.ca/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels) - [Hotels in Calidonia](https://expedia.ca/Calidonia-Panama-City-Hotels.0-n3000663488-0.Travel-Guide-Filter-Hotels) - [Hotels in Punta Paitilla](https://expedia.ca/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels) - [Hotels in San Felipe](https://expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [Hotels in Costa del Este](https://expedia.ca/Costa-Del-Este-Panama-City-Hotels.0-n3000663480-0.Travel-Guide-Filter-Hotels) - [Hotels in Marbella](https://expedia.ca/Marbella-Panama-City-Hotels.0-n3000663483-0.Travel-Guide-Filter-Hotels) - [Hotels in Punta Pacifica](https://expedia.ca/Punta-Pacifica-Panama-City-Hotels.0-n3000663482-0.Travel-Guide-Filter-Hotels) - [Hotels in Obarrio](https://expedia.ca/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Hotels in Campo Alegre](https://expedia.ca/Campo-Alegre-Panama-City-Hotels.0-n553248635976397615-0.Travel-Guide-Filter-Hotels) - [Hotels in Amador](https://expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels in Santa Ana](https://expedia.ca/Santa-Ana-Panama-City-Hotels.0-n553248623199107606-0.Travel-Guide-Filter-Hotels) - [Hotels in Balboa](https://expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - [Hotels in El Chorrillo](https://expedia.ca/El-Chorrillo-Panama-City-Hotels.0-n553248623199107689-0.Travel-Guide-Filter-Hotels) - [Hotels in Bethania](https://expedia.ca/Bethania-Panama-City-Hotels.0-n553248623199112069-0.Travel-Guide-Filter-Hotels) - [Hotels in Juan Diaz](https://expedia.ca/Juan-Diaz-Panama-City-Hotels.0-n553248623199113945-0.Travel-Guide-Filter-Hotels) - [Hotels in Parque Lefevre](https://expedia.ca/Parque-Lefevre-Panama-City-Hotels.0-n553248623199116155-0.Travel-Guide-Filter-Hotels) - [Hotels in Don Bosco](https://expedia.ca/Don-Bosco-Panama-City-Hotels.0-n829297665731731456-0.Travel-Guide-Filter-Hotels) ### Hotels near popular Panama City Attractions - [Hotels near Albrook Shopping Mall](https://expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Multiplaza Pacific Mall](https://expedia.ca/Multiplaza-Pacific-Mall-Hotels.0-l6158227-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa](https://expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Hotels near Via Espana](https://expedia.ca/Via-Espana-Hotels.0-l6125940-0.Travel-Guide-Filter-Hotels) - [Hotels near El Dorado Mall](https://expedia.ca/El-Dorado-Mall-Hotels.0-l553248621532963614-0.Travel-Guide-Filter-Hotels) - [Hotels near Fuerte Amador Resort & Marina](https://expedia.ca/Fuerte-Amador-Resort-Marina-Hotels.0-l553248621532964846-0.Travel-Guide-Filter-Hotels) - [Hotels near Veracruz Beach](https://expedia.ca/Veracruz-Beach-Hotels.0-l553248621562725884-0.Travel-Guide-Filter-Hotels) - [Hotels near Gamboa Rainforest Resort](https://expedia.ca/Gamboa-Rainforest-Resort-Hotels.0-l6078513-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Santa Ana - [Apartments in Panama City](https://expedia.ca/Panama-City-Apartments.d2897-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Panama City](https://expedia.ca/Panama-City-Condos.d2897-aaCondos.Travel-Guide-Accommodation) - [Vacation Homes in Panama City](https://expedia.ca/Panama-City-Private-Vacation-Homes.d2897-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Aparthotels in Panama City](https://expedia.ca/Panama-City-Apart-Hotels.d2897-aaApartHotels.Travel-Guide-Accommodation) - [Hostels in Panama City](https://expedia.ca/Panama-City-Hostels.d2897-aaHostels.Travel-Guide-Accommodation) - [B&B in Panama City](https://expedia.ca/Panama-City-Bed-And-Breakfast.d2897-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Panama City](https://expedia.ca/Panama-City-Guest-Houses.d2897-aaGuestHouses.Travel-Guide-Accommodation) - [Cottages in Panama City](https://expedia.ca/Panama-City-Cottages.d2897-aaCottages.Travel-Guide-Accommodation) - [Resorts in Panama City](https://expedia.ca/Panama-City-Resort-Hotels.d2897-aaResortHotels.Travel-Guide-Accommodation) - [Lodges in Panama City](https://expedia.ca/Panama-City-Lodges.d2897-aaLodges.Travel-Guide-Accommodation) - [Chalets in Panama City](https://expedia.ca/Panama-City-Chalets.d2897-aaChalets.Travel-Guide-Accommodation) - [Houseboats in Panama City](https://expedia.ca/Panama-City-Houseboats.d2897-aaHouseboats.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near Tocumen Intl. Airport](https://expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels) - [Hotels near Marcos A. Gelabert Intl. Airport](https://expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels) - [Hotels near Panama Pacifico Intl. Airport](https://expedia.ca/Panama-Pacifico-Intl-Airport-Hotels.0-aBLB-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Marriott Panama Hotel](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) - [JW Marriott Panama](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) - [Studio Coliving](https://expedia.ca/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) - [Decapolis Hotel Panama City](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) - [AC Hotel by Marriott Panama City](https://expedia.ca/Panama-City-Hotels-AC-Hotel-By-Marriott-Panama-City.h12880383.Hotel-Information) - [Waldorf Astoria Panama](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) - [Novotel Panama City](https://expedia.ca/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) - [Ramada Plaza By Wyndham Panama Punta Pacífica](https://expedia.ca/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) - [Plaza Paitilla Inn Hotel](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) - [Las Americas Golden Tower Panama](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) - [W Panama](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) - [Sofitel Legend Casco Viejo, Panama City](https://expedia.ca/Panama-City-Hotels-Sofitel-Legend-Casco-Viejo.h72981169.Hotel-Information) [See a list of all hotels in Panama City](https://expedia.ca/All-Panama-City-Hotels.d2897.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Inn at the Quay](https://expedia.ca/Vancouver-Hotels-Inn-At-The-Quay.h6898.Hotel-Information) - [Casco Viejo hotels](https://expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [City Centre Dublin hotels](https://expedia.ca/City-Centre-Dublin-Dublin-Hotels.0-n6176614-0.Travel-Guide-Filter-Hotels) - [Melia Madrid Princesa](https://expedia.ca/Madrid-Hotels-Melia-Madrid-Princesa.h11885.Hotel-Information) - [Tokyo Bay Shiomi Prince Hotel](https://expedia.ca/Tokyo-Hotels-Tokyo-Bay-Shiomi-Prince-Hotel.h44877300.Hotel-Information) - [Hyatt Place Richmond Airport](https://expedia.ca/Richmond-Hotels-Hyatt-Place-Richmond-Airport.h2385332.Hotel-Information) - [Luxury Hotels in Kamloops](https://expedia.ca/Kamloops-Hotels-Luxury-Hotel.0-0-d3979-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Comfort Inn Windsor](https://expedia.ca/Windsor-Hotels-Comfort-Inn-Windsor.h15971.Hotel-Information) Flights - [Cheap Flights from Toronto (YYZ) to Bengaluru (BLR)](https://expedia.ca/lp/flights/yyz/blr/toronto-to-bengaluru) - [Cheap Flights from Edmonton (YEG) to Perth (PER)](https://expedia.ca/lp/flights/yeg/per/edmonton-to-perth) - [Cheap Flights from Toronto (YYZ) to Manila (MNL)](https://expedia.ca/lp/flights/yyz/mnl/toronto-to-manila) - [Flights from Keflavik Intl. Airport](https://expedia.ca/lp/airports/kef/flights-from-keflavik-intl-airport) - [Cheap Flights from Winnipeg (YWG) to Beijing (PEK)](https://expedia.ca/lp/flights/ywg/pek/winnipeg-to-beijing) - [Cheap Flights from Toronto (YYZ) to São Paulo (GRU)](https://expedia.ca/lp/flights/yyz/gru/toronto-to-sao-paulo) - [Cheap Flights from Toronto (YYZ) to Vancouver (YVR)](https://expedia.ca/lp/flights/yyz/yvr/toronto-to-vancouver) - [Cheap Flights from Toronto (YYZ) to Calgary (YYC)](https://expedia.ca/lp/flights/yyz/yyc/toronto-to-calgary) - [Cheap Flights from Edmonton](https://expedia.ca/lp/flights/180002/flights-from-edmonton) - [Cheap Flights from Vancouver (YVR) to Bora Bora (BOB)](https://expedia.ca/lp/flights/yvr/bob/vancouver-to-bora-bora) - [Cheap Flights from Charlotte (CLT) to Orlando (MCO)](https://expedia.ca/lp/flights/clt/mco/charlotte-to-orlando) Cars - [Car rentals in Edmonton](https://expedia.ca/Car-Rentals-In-Edmonton.d180002.Car-Rental-Guide) - [Car rental Toronto Airport (YYZ)](https://expedia.ca/Car-Rentals-In-Pearson-Intl.d5921113.Car-Rental-Guide) Activities - [Things to do in Los Andes](https://expedia.ca/Things-To-Do-In-Los-Andes.d6272982.Travel-Guide-Activities) Packages - [Didsbury Aquatic Centre](https://expedia.ca/Didsbury-Aquatic-Centre-Didsbury.d6187280.Vacation-Attraction) General - [Visit Bella Vista](https://expedia.ca/Panama-City-Bella-Vista.dx3000663485) - [Visit Casco Viejo](https://expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Campo Alegre](https://expedia.ca/Panama-City-Campo-Alegre.dx553248635976397615) - [Visit Bishop's Falls](https://expedia.ca/Bishops-Falls.dx3000436493) - [Visit Old Town Historic District](https://expedia.ca/Niagara-On-The-Lake-Old-Town-Historic-District.dx6347821) - [Visit James Bay](https://expedia.ca/Victoria-James-Bay.dx6215774) - [Visit Calidonia](https://expedia.ca/Panama-City-Calidonia.dx3000663488)