Title: 10 Best Hotels in Santa Ana, Panama City for 2026 | Expedia.ca [Vacation Rentals in Panama City](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals)[Flights to Panama City](https://expedia.ca/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.ca/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Ana.d553248623199107606.Car-Rental-Guide)[Santa Ana Vacations](https://expedia.ca/Santa-Ana.d553248623199107606.Destination-Travel-Guides) ![Plaza Santa Ana, Panama Casco Viejo](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248623199107606/b6ad0470-c1f6-4b60-92c8-74bd8158bfc9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248623199107606&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Santa Ana hotels ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (68 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris CA $119 CA $130 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/w975h728x4y7-51ba2508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/c38aaf6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/3e5ecf32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) Santa Ana 7.6/10 Good (60 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) David CA $32 CA $36 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Apartment (20)](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/6c701342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (05) | Living area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/679f386c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15 reviews) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA CA $91 CA $138 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/ce5bf1ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/92156b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) Santa Ana 6.6/10 (183 reviews) "Super outdated. Looks dangerous in the area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina Kristine [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City)](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/096c0ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/f2fa3d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) Campo Alegre, 3.6 km from Santa Ana 9.0/10 Wonderful (4,929 reviews) " Nice hotel and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wajdi CA $188 CA $207 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/a4c743af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/49b75ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/d2ce5b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 7.4/10 Good (286 reviews) "The staff was super friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anneliase CA $116 CA $128 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Daily buffet breakfast (PAB 10 per person)](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/b50bcacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/14f91618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/675171b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/7c4bef31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospedium Princess Hotel Panama [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) Obarrio, 3.6 km from Santa Ana 7.4/10 Good (755 reviews) "Very polite staff and great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scot Da CA $70 CA $77 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/dc6a5657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/88cca748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/700fef33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) 19.8 km from Santa Ana 8.6/10 Excellent (1,851 reviews) "Very nice staff and confortable stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARIA CA $171 CA $188 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/ab95ae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/86e96c74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/486951c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, City View | View from room](https://images.trvl-media.com/lodging/9000000/8790000/8785100/8785045/d12ffdbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sortis Hotel, Spa & Casino, Autograph Collection by Marriott [](https://www.expedia.ca/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) Obarrio, 4.1 km from Santa Ana 8.8/10 Excellent (1,004 reviews) "Resteraunts, location, rooms all very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanne CA $217 CA $239 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Panama-City-Hotels-Sortis-Hotel.h8785045.Hotel-Information) ![2 bars/lounges, gastropub](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/f3b8e5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/96fd75ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/d27e0b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine](https://images.trvl-media.com/lodging/1000000/190000/185300/185277/6db7ada6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Urban Hotel [](https://www.expedia.ca/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) El Cangrejo, 3.8 km from Santa Ana 8.8/10 Excellent (1,054 reviews) "Clean spacious room and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $115 CA $126 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Panama-City-Hotels-Riande-Urban-Hotel.h185277.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/5f648ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) 21.1 km from Santa Ana 8.6/10 Excellent (2,412 reviews) "Very nice hotel and good restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allen CA $161 CA $177 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive lounge](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/cd74829c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/44769fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/e8a459e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama [](https://www.expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) Punta Paitilla, 3.6 km from Santa Ana 9.0/10 Wonderful (1,009 reviews) "excellent room and location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jon CA $226 CA $251 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/14a856db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/69984cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/961958f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) Punta Paitilla, 3.5 km from Santa Ana 8.4/10 Very good (1,405 reviews) "Clean room,helpful staff around the hotel,good food options" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Umar CA $302 CA $332 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/91000000/90160000/90152300/90152211/8f68f518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/91000000/90160000/90152300/90152211/e6e5fe52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/91000000/90160000/90152300/90152211/85dc8880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/91000000/90160000/90152300/90152211/5988427f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MARINN Tropical Vibes Hotel [](https://www.expedia.ca/Amador-Hotels-Hotel-Mar-Inn-Tropical-Vibes.h90152211.Hotel-Information) Amador, 4.8 km from Santa Ana 8.2/10 Very good (219 reviews) "Great rooms, pleasant staff, lovely location, lots of eats and drinks options" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rajiv Sachin CA $95 CA $104 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Amador-Hotels-Hotel-Mar-Inn-Tropical-Vibes.h90152211.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/4ac2734a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/5b3a3c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually furnished](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/05c7fc0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel [](https://www.expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) Punta Paitilla, 3.4 km from Santa Ana 9.4/10 Exceptional (2,166 reviews) "Hotel was very clean, the staff was very helpful and the breakfast was very good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monty CA $165 CA $181 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![4 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed, Partial Ocean View](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/2c21fbc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/08d313d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/w3996h2667x4y0-a167c2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Panama [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) Punta Pacifica, 4.3 km from Santa Ana 9.0/10 Wonderful (1,006 reviews) "Beautiful hotel, great service. Breakfast buffet is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara CA $312 CA $344 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/19fc3193.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/febf3b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/1c0cddf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/cc0414b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ORHO HOTEL BOUTIQUE PANAMA Airport [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) 20.5 km from Santa Ana 9.0/10 Wonderful (64 reviews) "Clean room, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $164 CA $212 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) ![Outdoor pool, open 8:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/e3ee3bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/af0ce5c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/5b910cc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/243f1471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Executive Hotel [](https://www.expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) Campo Alegre, 3.2 km from Santa Ana 9.2/10 Wonderful (1,016 reviews) "Breakfast was excellent, Rooms are lovely " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kera Michele Naomi CA $115 CA $126 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Flat-screen TV, iPod dock](https://images.trvl-media.com/lodging/4000000/3920000/3918000/3917923/bf98e226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Double Beds](https://images.trvl-media.com/lodging/4000000/3920000/3918000/3917923/047820e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/4000000/3920000/3918000/3917923/fb08b4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/4000000/3920000/3918000/3917923/0f88407a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Victoria Hotel and Suites Panama [](https://www.expedia.ca/Panama-City-Hotels-Victoria-Hotel-And-Suites-Panama.h3917923.Hotel-Information) El Cangrejo, 3.5 km from Santa Ana 8.2/10 Very good (1,002 reviews) "Staff was amazing, my second time staying at the hotel and I'll definitely be back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paula CA $98 CA $108 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Panama-City-Hotels-Victoria-Hotel-And-Suites-Panama.h3917923.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este, 10.2 km from Santa Ana 9.4/10 Exceptional (204 reviews) "Excellent space, great layout, friendly staff, responsive staff. Will stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nick CA $113 CA $187 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. - Casco Viejo - Bella Vista - El Cangrejo - San Felipe - San Francisco ![Panama City view old casco viejo antiguo](https://images.trvl-media.com/place/6285189/2d543e5b-dc8c-4a1e-9872-eb2afab3bfc9.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![#ciudaddepanama](https://images.trvl-media.com/place/2897/03378482-6fa2-4594-96ce-513a22a4250a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Hideki Yamagata ![You can find Simon Boliva statue in most Latin America countries ](https://images.trvl-media.com/place/2897/fefd5676-1a9e-4e1c-80d1-a091935f3d74.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![A good contrast, modern high rise behind and colonial houses in front ](https://images.trvl-media.com/place/2897/4c35bf40-b641-4f9b-89ba-fd0b28f2788d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![Nice place to walk around here](https://images.trvl-media.com/place/2897/c5bfc50a-faf0-4497-80c7-103bab605406.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285189) ![Nice building, highlight on Panama's skyline.](https://images.trvl-media.com/place/2897/e7a58ce8-b6f0-462e-9d0a-c00e40ae732b.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by My World ![#aboveitall](https://images.trvl-media.com/place/2897/bfaeea70-86e7-4f1f-82e7-58c757650d86.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Freddy Dominguez ![Old meets new](https://images.trvl-media.com/place/2897/fd510f83-463e-4e76-bf4b-a18c3454a601.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Journey Of A Nomadic Family ![The F&F Tower 242,9m (previously known as the Revolution Tower) is an office tower in Panama City. Emporis selected the F&F Tower among the top 10 best skyscrapers of the year in 2011, ranking it 7th out of the 10 Emporis Skyscraper Award winners for its architectural excellence regarding the design of building and its functionality. It is also one of the most iconic buildings of Panama City. #tower #revolutiontower #spiral #spiraltower](https://images.trvl-media.com/place/2897/3edf9c75-3949-41fd-b2bd-528cc7de3979.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel](https://images.trvl-media.com/place/2897/62672ebb-ab68-4df6-9850-2c73cf428908.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Fabiola Tile [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663485) ![Panama City Old Town streets and buildings](https://images.trvl-media.com/place/6285972/af7e9b24-0964-44fc-86b9-7efe328f4d40.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Panama viejo](https://images.trvl-media.com/place/2897/d98db3e6-d3e9-49ce-91f9-f7e6597dfbef.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Garrett Britton [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6285972) ![Balcony of a colonial house, Casco Viejo, Panama City, Panama, Central America](https://images.trvl-media.com/place/829297728598073344/b153dfc8-01d6-40ec-9e98-642d0f1b8062.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![#ciudaddepanama](https://images.trvl-media.com/place/2897/03378482-6fa2-4594-96ce-513a22a4250a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Hideki Yamagata ![A good contrast, modern high rise behind and colonial houses in front ](https://images.trvl-media.com/place/2897/4c35bf40-b641-4f9b-89ba-fd0b28f2788d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![Nice place to walk around here](https://images.trvl-media.com/place/2897/c5bfc50a-faf0-4497-80c7-103bab605406.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon ![You can find Simon Boliva statue in most Latin America countries ](https://images.trvl-media.com/place/2897/fefd5676-1a9e-4e1c-80d1-a091935f3d74.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Botak Jon [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=829297728598073344) ![San Felipe map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### San Felipe If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=829297728598073344) ![The Bridge of the Americas in summer, Panama City](https://images.trvl-media.com/place/553248623199112076/b14d4c65-cc25-49b4-aad3-c708d5b994fc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![La entrada a la Ciudad de Panamá ](https://images.trvl-media.com/place/2897/df27e517-e0be-4550-bc06-92be5954aac5.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Karla Jimenez ![Hard Rock Hotel Panama #StunningStructures](https://images.trvl-media.com/place/2897/295f53ea-71ed-49f8-9430-8d4fd3fac6c7.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![Panama #StunningStructures](https://images.trvl-media.com/place/2897/bcdd62da-f297-44f7-93bd-f5423e81a7d2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian ![#StunningStructures impressive view of Panama City from Hardrock Hotel Megapolis](https://images.trvl-media.com/place/2897/6084884e-9927-4c00-865b-1ba27cd82b32.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Adrian Damian [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50\. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248623199112076) ## Top Santa Ana Hotel Reviews ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg) ### W Panama 10/10 Excellent "Clean room staff everything was amazing " [](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "This hotel has a fantastic location—just steps from the seaside walk/strip, which made it easy to get out and enjoy the area. The lobby is beautiful and clean, and the front desk staff were incredibly helpful, especially since my Spanish skills are basically non-existent. They were patient, kind, and welcoming from the moment we arrived. One thing that really stood out was the large dining area. You have several options: sitting at the bar, outdoor seating, or indoor seating—three different areas depending on the vibe you want. Breakfast is included and was exceptional. There were so many choices, from Panamanian dishes to American options. Coffee and juice are free, and if you want an espresso, cappuccino, or latte, those are available for a small additional cost—which I didn’t mind at all. They also had an omelette station, though there was usually a line, so I didn’t get a chance to try it. The dining staff were just as friendly and attentive as the front desk. Our room was fantastic—very clean, very spacious, and the view was absolutely amazing. Overall, this was a wonderful stay, and I would absolutely recommend this hotel to anyone visiting Panama City." [](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "We had a great stay at the RIU. Our room was spacious, clean and quiet. Our check in with Luis was great and very fast! We had great service at the main restaurant from Melissa and then again at breakfast. Mellisa was a wonderful server and she spoke very good English which is helpful to me as I am still learning Spanish. The buffet breakfast is amazing. We also enjoyed a nice afternoon at the pool. We did had a bad experience on Saturday at the main bar. We came to bar and sat down and waited. We were never acknowledged and the tall female bartender never made eye contact with us and never spoke to us. Then a new male bartender came and he did the same and ignored us. He then waited on a couple that had come to the bar after us. The bar was not busy. There were 3 couples there counting us. Maybe it was because my wife is Latina and I am Americano? Not sure what their issue was. Service can be slow in Panamá but this was different. We just left and went to the main restaurant where we ordered a nice model of wine an appetizers and this is where we experienced great, friendly service from Melissa. All in all a great hotel and we will return and we would recommend the hotel. " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Cleanliness Nice" [](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Everything was excellent ! When I arrived the room I reserve for a reason was not ready and they gave me a much much better room at no adicional cost. Thank you!" [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Good" [](https://expedia.ca/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Casco View Apartments](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce_y.jpg) ### Casco View Apartments 10/10 Excellent "Everything was great. Staff room etc" [](https://expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Nice stuff. Very welcoming and cheerful people. Clean. Closhopping centers " [](https://expedia.ca/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The location was terrific making it easy to catch an Uber to pretty much anywhere you wanted to go. Pool & fitness area were as expected & the room was comfortable. We were here for 4 nights. Loved that it was attached to the mall." [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ## Find out more about Santa Ana ### Top reasons to visit Santa Ana - **Historical Attractions:** Visit significant sites like the Santa Ana Church and Iglesia Santa Ana to experience the rich cultural heritage of the area. - **Charming Walking Tours:** Enjoy guided walking tours led by locals, showcasing the unique charm and highlights of Santa Ana. - **Relaxing Green Spaces:** Spend time at Santa Ana Square, a perfect spot for relaxation and enjoying scenic views. - **Diverse Accommodations:** Choose from a wide range of lodging options, from budget to luxury, catering to all types of travelers. - **Proximity to Attractions:** Easily access nearby popular attractions like Casco Viejo and Parque Natural Metropolitano for day trips. ### Find great hotels near Santa Ana Santa Ana boasts a diverse selection of accommodations, catering to every traveler's needs, from budget-friendly lodgings to luxurious 5-star hotels. Whether you're seeking a charming lodge or a modern hotel, you'll find options that provide essential services for city exploration, business trips, or a pet-friendly getaway. Discover the best hotels in Santa Ana and enjoy a memorable stay in the heart of Panama City. - **[Central Hotel Panama Casco Viejo:](https://www.expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information)** Nestled in the vibrant Casco Viejo district, Central Hotel Panama offers a romantic and luxurious environment perfect for couples and business travellers alike. This 4-star gem is renowned for its exceptional spa services, featuring a full-service spa, steam room, and facial treatments to soothe your senses. With a strong focus on romance, guests can indulge in packages that include champagne service and 24-hour room service. For business needs, the hotel provides accessible meeting rooms and conference spaces, ensuring a seamless experience for professionals. - **[American Trade Hotel:](https://www.expedia.ca/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information)** Located in the heart of Panama City, the American Trade Hotel blends adventure, family-friendly amenities, and romantic touches into a unique lodging experience. This 4.5-star hotel boasts proximity to outdoor activities such as biking, hiking, and even Segway rentals, making it ideal for adventurous families. Guests can enjoy garden views from the restaurant while savouring limited-hour room service and champagne service. The outdoor pool area, complete with sun loungers and in-room massage options, provides a relaxing retreat for couples seeking a romantic getaway. - **Sofitel Legend Casco Viejo, Panama City:** This 5-star luxury hotel embodies elegance and sophistication in the historic Casco Viejo area. With a strong emphasis on business and leisure, it offers accessible business centres and comprehensive facilities for corporate travellers. Guests can unwind at the spa, which features treatment rooms and a swim-up bar, perfect for relaxation after a busy day. The hotel's exquisite design and top-notch services make it a premier choice for discerning travellers looking for an unforgettable experience in Panama City. ### Where to stay near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly activities and historical charm. Explore the bustling streets filled with friendly locals, and immerse yourself in the unique atmosphere of Panama's capital. Nearby, attractions like the historic Casco Viejo and the scenic Parque Natural Metropolitano provide perfect day trips. Whether you’re seeking a city-themed adventure or a relaxing family holiday, Santa Ana is an ideal base for discovering the rich culture of Panamá Province. - **[Panama City:](https://www.expedia.ca/Panama-City-Hotels.d2897.Travel-Guide-Hotels)** As the vibrant capital of Panama, Panama City is a bustling metropolis rich in culture and history. Nestled in the heart of the country, it offers a diverse travel experience, appealing to families, business travellers, and city explorers alike. The city showcases a stunning mix of modern skyscrapers and colonial architecture. Visitors can enjoy shopping at prominent centres and malls, while the nearby beaches, parks, and lively streets invite exploration and relaxation. With visitor numbers peaking in January, July, and September, it's an ideal destination year-round. - **[Casco Viejo:](https://www.expedia.ca/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels)** Located a mere 644m from Santa Ana, Casco Viejo is a UNESCO World Heritage site known for its charming cobblestone streets and historic buildings. This neighbourhood is a hub of activity, making it perfect for families and city adventurers. With vibrant shopping centres, resorts, and delightful dining options, Casco Viejo is a picturesque setting for exploration. Enjoy the nearby beaches and parks, as well as the unique street life that adds to its cultural richness. Peak visitor months include January and March to April, offering a lively atmosphere. - **[San Felipe:](https://www.expedia.ca/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels)** Also situated 644m away from Santa Ana, San Felipe is a captivating neighbourhood known for its historic significance and charming streets. This area attracts families, business travellers, and city explorers, offering a mix of shopping malls and local boutiques. Visitors can explore the nearby beaches, historic places, and monuments that tell the story of Panama's past. With peak tourist arrivals from December to February, San Felipe provides a vibrant yet tranquil atmosphere for a memorable vacation. ### Things to do near Santa Ana Santa Ana, a vibrant neighbourhood in Panama City, is perfect for family and business vacations. Visitors can enjoy a variety of activities, including exploring shopping malls and unique shopping areas. Don't miss the chance to embark on a walking tour of Santa Ana, guided by knowledgeable locals, to discover touristy spots and enjoy pleasant strolls through this charming district. **Shopping** In Santa Ana, you can visit Avenida Central, located 483m away, offering a vibrant mix of family-friendly shops and entertainment. Albrook Shopping Mall, just 1.6km away, is perfect for family outings. If you're up for a drive, check out Uruguay Street, located 3.2km away, for more local shopping experiences. **Recreation** Experience the vibrant atmosphere at [Maracana Stadium](https://www.expedia.ca/Maracana-Stadium-Hotels.0-l553248621562725885-0.Travel-Guide-Filter-Hotels), located 1.3km from Santa Ana, perfect for sports enthusiasts. For an exhilarating outing, head to Estadio Nacional Rod Carew, 9.7km away, or Estadio Rommel Fernandez, 11.3km away, both offering thrilling sports events and energetic vibes. **Adventure** Embark on the Honeycreeper Ridge Trail, located 211.3km from Santa Ana, for a scenic hike surrounded by vibrant nature. For a thrilling experience, visit Gatun Eco Adventures, situated 48.3km away, where you can soar through the treetops on an exhilarating zipline ropes course. **Nightlife** Experience the vibrant nightlife in Santa Ana by visiting Crown Casino, just 3.2km away, for thrilling games and romance. For a cultural evening, enjoy a show at the National Theater (0.9.7km away) or Anita Villalaz Theater (1.3km away), both offering family-friendly entertainment and a romantic atmosphere. ### Booking tips and Expedia advantages for Santa Ana When visiting Santa Ana, Panama, consider exploring free attractions like Albrook Shopping Mall and Cinta Costera. To save on accommodation, travel during the off-peak months from September to November, when prices are lower compared to peak times like March and December to January. Tuesdays are typically the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare prices and book packages that combine flights and hotels for added savings. Don't forget to filter for eco-certified hotels to find sustainable options that fit your budget. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to choose your budget, preferred location, and additional criteria. You can easily sort your results to display prices from lowest to highest, allowing you to find the most affordable hotels right away. Additionally, you can refine your choices by hotel type—select the "Eco-certified" filter to discover sustainable and environmentally-friendly accommodations available for booking. - **Consider bundling your trip:** You can save money by combining your Santa Ana hotel reservation with your flights and activities when you book an Expedia package. ### Find the best attractions near Santa Ana Santa Ana, located in Panama City, is perfect for family and business vacations, offering a rich cultural experience. Visitors can explore historical sites such as the Santa Ana Church and Iglesia Santa Ana, relax at Santa Ana Square, and enjoy scenic views near the canyon. The area's attractions cater to those seeking a blend of history and city life, making it an ideal destination for tourists looking to immerse themselves in local culture. - **[Metropolitan Cathedral of Panama:](https://www.expedia.ca/Metropolitan-Cathedral-Of-Panama-Hotels.0-l6078477-0.Travel-Guide-Filter-Hotels)** Located 805m from Santa Ana, this stunning cathedral showcases remarkable colonial architecture and intricate artwork. It serves as a cultural hub, offering a glimpse into Panama's rich history and religious heritage. - **Ancon Hill:** Just 966m from Santa Ana, Ancon Hill provides breathtaking panoramic views of Panama City and the Panama Canal. This outdoor oasis is perfect for hiking and enjoying nature while immersing yourself in the area's scenic beauty. - **Interoceanic Canal Museum:** Situated 805m away, this museum is dedicated to the history of the Panama Canal. It features fascinating exhibits that highlight the canal's significance, making it a must-visit for culture enthusiasts. ### Best time to go to Santa Ana Visitor numbers around Santa Ana is generally unchanged in popularity throughout the year. The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain. | **![calendar icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly cloudy icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation rate icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price icon](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------------------ | ------------------------------------------------------------------------------------------------------------------ | | January | 78.8°F (26.0°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Slightly High | | February | 79.2°F (26.2°C) | No Rain (Dry) | Mostly Sunny | Slightly High | Average | | March | 79.7°F (26.5°C) | No Rain (Dry) | Mostly Sunny | Average | Slightly High | | April | 80.4°F (26.9°C) | Light Rain | Mostly Sunny | Average | Average | | May | 80.2°F (26.8°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | June | 79.9°F (26.6°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Average | | July | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Average | Average | | August | 79.2°F (26.2°C) | Frequent Rain | Mostly Cloudy | Average | Average | | September | 79.3°F (26.3°C) | Frequent Rain | Mostly Cloudy | Slightly Low | Slightly Low | | October | 78.6°F (25.9°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | November | 78.3°F (25.7°C) | Frequent Rain | Mostly Cloudy | Average | Slightly Low | | December | 78.6°F (25.9°C) | Light Rain | Mostly Cloudy | Slightly High | Slightly High | ### The nearest major airports for your trip to Santa Ana When visiting Santa Ana, you have convenient access to two major airports. Panama City ([PTY](https://www.expedia.ca/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels)\-Tocumen Intl.) is located 20.9km away, with notable hotels like [The Santa Maria](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information), A Luxury Collection Hotel & Golf Resort, 8.0km from the airport, and [JW Marriott Panama](https://www.expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information), 16.1km away. Alternatively, Panama City ([PAC](https://www.expedia.ca/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels)\-Marcos A. Gelabert Intl.) is only 3.2km from Santa Ana, featuring excellent accommodations such as [Waldorf Astoria Panama](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information), just 3.2km away, and [Hilton Panama](https://www.expedia.ca/Panama-City-Hotels-Hilton-Panama.h5938139.Hotel-Information), 4.8km away. Transportation services from these hotels to the airports typically include on-request shuttle services, offering ease and comfort for your travel needs. ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.ca/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [5 Star Hotels in Casco Viejo ](https://www.expedia.ca/5Star-Casco-Viejo-Panama-City-Hotels.s50-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels near Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Amador Hotels ](https://www.expedia.ca/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Avenida Balboa ](https://www.expedia.ca/Avenida-Balboa-Hotels.0-l553248623453290531-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels ](https://www.expedia.ca/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - 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[Flights from Merida (MID) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/mid/pac/merida-to-panama-city) - [Flights from Mamfe (MMF) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/mmf/pac/mamfe-to-panama-city) - [Flights from Madison (MSN) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/msn/pac/madison-to-panama-city) - [Flights from Orlando (ORL) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/orl/pac/orlando-to-panama-city) - [Flights from Port of Spain (POS) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/pos/pac/port-of-spain-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from Puerto Vallarta (PVR) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/pvr/pac/puerto-vallarta-to-panama-city) - [Flights from Rio Hato (RIH) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/rih/pac/rio-hato-to-panama-city) - [Flights from South Bend (SBN) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/sbn/pac/south-bend-to-panama-city) - [Flights from Tambor (TMU) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/tmu/pac/tambor-to-panama-city) - [Flights from Edmonton (YEG) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yeg/pac/edmonton-to-panama-city) - [Flights from Halifax (YHZ) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yhz/pac/halifax-to-panama-city) - [Flights from Kelowna (YLW) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/ylw/pac/kelowna-to-panama-city) - [Flights from Ottawa (YOW) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yow/pac/ottawa-to-panama-city) - [Flights from Montreal (YUL) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yul/pac/montreal-to-panama-city) - [Flights from Vancouver (YVR) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yvr/pac/vancouver-to-panama-city) - [Flights from Saskatoon (YXE) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yxe/pac/saskatoon-to-panama-city) - [Flights from Calgary (YYC) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yyc/pac/calgary-to-panama-city) - [Flights from Toronto (YYZ) to Panama City (PAC) ](https://www.expedia.ca/lp/flights/yyz/pac/toronto-to-panama-city) - [Albrook Shopping Mall ](https://www.expedia.ca/Albrook-Shopping-Mall-Panama-City.d6159851.Vacation-Attraction) - [Cinta Costera ](https://www.expedia.ca/Cinta-Costera-Calidonia.d6245970.Vacation-Attraction) - [Club de Clases y Tropas ](https://www.expedia.ca/Club-De-Clases-Y-Tropas-Casco-Viejo.d553248621532965263.Vacation-Attraction) - [Maracana Stadium ](https://www.expedia.ca/Maracana-Stadium-El-Chorrillo.d553248621562725885.Vacation-Attraction) - [Visit Balboa ](https://www.expedia.ca/Panama-City-Balboa.dx6323179) - [Visit Calidonia ](https://www.expedia.ca/Panama-City-Calidonia.dx3000663488) - [Visit Casco Viejo ](https://www.expedia.ca/Panama-City-Casco-Viejo.dx6285189) - [Visit Curundu ](https://www.expedia.ca/Panama-City-Curundu.dx553248623199107736) - [Visit El Chorrillo ](https://www.expedia.ca/Panama-City-El-Chorrillo.dx553248623199107689) - [Panamá Province Vacations ](https://www.expedia.ca/Panama-Province.d6246281.Destination-Travel-Guides) - [Visit Panamá Province ](https://www.expedia.ca/Panama-Province.dx6246281) - [Car rentals near Albrook Shopping Mall ](https://www.expedia.ca/Car-Rentals-In-Albrook-Shopping-Mall.d6159851.Car-Rental-Guide) - [Car rentals near Balboa ](https://www.expedia.ca/Car-Rentals-In-Balboa.d6323179.Car-Rental-Guide) - [Panamá Province Vacation Rentals ](https://www.expedia.ca/Destinations-In-Panama-Province.d6246281.Vacation-Rental-Destinations)