Title: Visit San Sisto: Best of San Sisto Tourism | Expedia Travel Guide - Expedia.ca [Hotels in San Sisto](https://expedia.ca/San-Sisto-Hotels.d3000377291.Travel-Guide-Hotels)[Vacation Rentals in San Sisto](https://expedia.ca/San-Sisto-Vacation-Rentals.d3000377291.Travel-Guide-VacationRentals)[San Sisto Car Rentals](https://expedia.ca/Car-Rentals-In-San-Sisto.d3000377291.Car-Rental-Guide)[San Sisto Vacation Packages](https://expedia.ca/San-Sisto.d3000377291.Destination-Travel-Guides) # San Sisto ## Travel Guide ## Visit San Sisto Things to do - San Sisto Hotel Deals - Vacation Rentals in San Sisto ![TH Assisi - Hotel Cenacolo](https://images.trvl-media.com/lodging/4000000/3490000/3485400/3485400/60a89c43_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### TH Assisi - Hotel Cenacolo Viale Patrono d'Italia 70 Assisi PG CA $101 CA $121 total Jan 11 - Jan 12, 2026 includes taxes & fees Book a stay at this business-friendly hotel in Assisi. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ... 9/10 Wonderful! (600 reviews) Very clean room and friendly staff. About 10 min drive up to Asisi parking lot and bus stop. Reviewed on Dec 3, 2025 [](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=3485400&PinnedHotelID=3485400&HadPinnedHotel=true®ionId=3000377291) ![La Meridiana Bleisure Hotel](https://images.trvl-media.com/lodging/2000000/1170000/1166700/1166614/02e605ea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Meridiana Bleisure Hotel 42 del Discobolo St. Perugia PG CA $143 CA $163 total Dec 15 - Dec 16 includes taxes & fees Book a stay at this family-friendly hotel in Perugia. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ... 8.4/10 Very Good! (320 reviews) The best hotel and seevices u can ever have. Definitely recommend!! Reviewed on Oct 16, 2025 [](https://expedia.ca/Hotel-Search?startDate=15%2F12%2F2025&endDate=16%2F12%2F2025&selected=1166614&PinnedHotelID=1166614&HadPinnedHotel=true®ionId=3000377291) ![Giotto Hotel & Spa](https://images.trvl-media.com/lodging/3000000/2550000/2544400/2544317/c322aa7a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Giotto Hotel & Spa Via Fontebella 41 Assisi PG Book a stay at this spa hotel in Assisi. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ... 8.8/10 Excellent! (757 reviews) Perfect location! We loved this hotel, the staffs are super friendly and nice-restaurants, front desk and the bar! We were upgraded to a big and best view with balcony and was given complimentary bar drink-thank you! Definitely will stay here again! Reviewed on Dec 1, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=2544317&PinnedHotelID=2544317&HadPinnedHotel=true®ionId=3000377291) [](https://expedia.ca/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=2544317&PinnedHotelID=2544317&HadPinnedHotel=true®ionId=3000377291) [See all 3,398 properties in San Sisto](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=15%2F12%2F2025&endDate=16%2F12%2F2025®ionId=3000377291) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Welchome suites](https://images.trvl-media.com/lodging/112000000/111280000/111270500/111270465/577f8112_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Welchome suites Via Luigi Bonazzi 45 Perugia PG Stay at this apartment in Perugia. Enjoy free WiFi, in-room massages, and laundry facilities. Popular attractions Museo delle Porte e delle Mura Urbiche and ... 9.2/10 Wonderful! (15 reviews) Amazing value, great location, very clean and friendly hosts. Reviewed on Nov 1, 2025 [](https://expedia.ca/Perugia-Hotels-Welchome-Suites.h111270465.Hotel-Information) ![Aethos Saragano](https://images.trvl-media.com/lodging/12000000/11090000/11081700/11081699/d0bd88da_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Aethos Saragano Via Milano 20 Gualdo Cattaneo PG Book a stay at this spa aparthotel in Gualdo Cattaneo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sanctuary of Madonna della Valle ... 9.4/10 Exceptional! (28 reviews) This hotel is a gem! The staff was amazing! The continental breakfast was very good! Our room was amazing! Would highly recommend staying here on your next trip to the Umbria region! Reviewed on Oct 13, 2025 [](https://expedia.ca/Gualdo-Cattaneo-Hotels-Aethos-Saragano.h11081699.Hotel-Information) ![Tenuta Borgo San Michele](https://images.trvl-media.com/lodging/115000000/114210000/114206100/114206048/226453e6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Tenuta Borgo San Michele Località Coldimolino Gubbio PG Stay at this aparthotel in Gubbio. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Porta Romana and Teatro Romano are located nearby. 9.2/10 Wonderful! (5 reviews) Breakfast was great. The rain brought to many insects. Reviewed on Sep 28, 2025 [](https://expedia.ca/Gubbio-Hotels-Tenuta-Borgo-San-Michele.h114206048.Hotel-Information) [See all properties in San Sisto](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=3000377291&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check San Sisto hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=2025-12-14&endDate=2025-12-15)[Dec 14 - Dec 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=2025-12-14&endDate=2025-12-15) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=2025-12-15&endDate=2025-12-16)[Dec 15 - Dec 16](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=2025-12-15&endDate=2025-12-16) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025)[Dec 19 - Dec 21](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=3000377291&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025) ### Popular places to visit ![Piazza IV Novembre featuring heritage architecture and a city as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/158000/158324-Piazza-Iv-Novembre.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza IV Novembre 4.5/5(6 reviews) Located in the heart of Perugia, this small square is surrounded by some of the town’s most impressive landmarks. [](https://expedia.ca/Piazza-IV-Novembre-Old-Town-Perugia.d6073770.Vacation-Attraction) ![Perugia featuring a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/54000/54255-Perugia.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Corso Vannucci 4/5(1 review) Learn about the local history of Perugia with a stop at Corso Vannucci. You can enjoy the bars while in the area. [](https://expedia.ca/Corso-Vannucci-Perugia.d6169863.Vacation-Attraction) ![Roman Aqueduct showing a small town or village and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/158000/158544-Roman-Aqueduct.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Roman Aqueduct Stroll along the top of an ancient waterway, now a picturesque path that cuts through the heart of Perugia’s old town. [](https://expedia.ca/Roman-Aqueduct-Old-Town-Perugia.d6188057.Vacation-Attraction) ![Basilica San Pietro featuring interior views, religious aspects and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/158000/158354-Basilica-Di-San-Domenico.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Basilica San Pietro 5/5(8 reviews) Explore one of the oldest monastic complexes in central Italy, known for its ancient works of art and medieval garden. [](https://expedia.ca/Basilica-San-Pietro-Old-Town-Perugia.d6077838.Vacation-Attraction) ![Rocca Paolina featuring heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/158000/158262-Rocca-Paolina.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rocca Paolina 4.5/5(3 reviews) Explore a maze of tunnels and alleys, and visit markets, events and exhibitions in the foundations of a 16th-century fortress. [](https://expedia.ca/Rocca-Paolina-Old-Town-Perugia.d6073792.Vacation-Attraction) ![National Gallery of Umbria showing signage and heritage architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/158000/158458-National-Gallery-Of-Umbria-Galleria-Nazionale-Dellumbria.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### National Gallery of Umbria 5/5(2 reviews) Discover Umbria’s cultural treasures at its most comprehensive art gallery, where centuries-old works of art bring the past to life. [](https://expedia.ca/National-Gallery-Of-Umbria-Old-Town-Perugia.d6077890.Vacation-Attraction) ### Things to do ![From Rome: Explore Assisi, Civita di Bagnoregio & Orvieto](https://mediaim.expedia.com/localexpert/49429736/0e1c7232-51d3-408f-a018-aada8a50734d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rome Day Tour to Assisi, Civita di Bagnoregio & Orvieto CA $180 per adult **88%** of travellers recommend [](https://expedia.ca/things-to-do/rome-day-tour-to-assisi.a49429736.activity-details) ![Perugia: Old Town Walking Tour, Piazza IV Novembre](https://mediaim.expedia.com/localexpert/44633641/1bc1676c-aa29-4795-ae71-25d4218bd12e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Perugia: Old Town Walking Tour, Piazza IV Novembre CA $48 per adult [](https://expedia.ca/things-to-do/perugia-old-town-walking-tour.a44633641.activity-details) ![Assisi: Wine tasting, gourmet pairing, walk in the vineyards](https://mediaim.expedia.com/localexpert/47495588/957f4cd1-ec63-4019-90d8-f50fc38b3e8f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Assisi: Wine tasting, gourmet pairing, walk in the vineyards CA $40 per adult [](https://expedia.ca/things-to-do/assisi-wine-tasting.a47495588.activity-details) ![Small Group Tour of Assisi and St. Francis Basilica visit](https://mediaim.expedia.com/localexpert/1175620/2e5c3728-f1c5-4e1c-9bf1-e1ccb772bb91.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Small Group Tour of Assisi and St. Francis Basilica CA $73 per adult **96%** of travellers recommend [](https://expedia.ca/things-to-do/small-group-tour-of-assisi-and-st-francis-basilica.a1175620.activity-details) ![Perugia: Chapter Museum Entry Ticket](https://mediaim.expedia.com/localexpert/48827216/b6c3a433-f3ea-4486-8939-4d2bf83cba47.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Raphael temporary exhibit: Chapter Museum of Saint Lorenzo CA $13 per adult [](https://expedia.ca/things-to-do/raphael-temporary-exhibit-chapter-museum-of-saint-lorenzo.a48827216.activity-details) ![E - Tuk Panoramic Tour Assisi with audio guides](https://mediaim.expedia.com/localexpert/50477546/a6f8e37f-b0ee-4479-99fd-dcb4ab0f9d8b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### E - Tuk Panoramic Tour Assisi with audio guides CA $48 per adult [](https://expedia.ca/things-to-do/e-tuk-panoramic-tour-assisi-with-audio-guides.a50477546.activity-details) [See all activities in San Sisto](https://expedia.ca/Things-To-Do-In-San-Sisto.d3000377291.Travel-Guide-Activities) ## Cities near San Sisto ![Perugia featuring a city](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/54000/54255-Perugia.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Perugia ![Photo by Giorgia Bachiorri ](https://mediaim.expedia.com/destination/2/288a0eca196300d7bb4325c09690edc6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Corciano ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Province of Perugia Hotels ](https://www.expedia.ca/Destinations-In-Province-Of-Perugia.d6046902.Hotel-Destinations) - 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[Visit Monte Petriolo ](https://www.expedia.ca/Monte-Petriolo.dx3000027401) - [Visit Monte Vibiano Vecchio ](https://www.expedia.ca/Monte-Vibiano-Vecchio.dx6123406) - [Visit Montecolognola ](https://www.expedia.ca/Montecolognola.dx553248627537501323) - [Visit Morcella ](https://www.expedia.ca/Morcella.dx553248635149813623) - [National Gallery of Umbria ](https://www.expedia.ca/National-Gallery-Of-Umbria-Old-Town-Perugia.d6077890.Vacation-Attraction) - [Visit Panicale ](https://www.expedia.ca/Panicale.dx6123564) - [Visit Panicarola ](https://www.expedia.ca/Panicarola.dx3000435067) - [Visit Pantanella ](https://www.expedia.ca/Pantanella.dx3000027106) - [Visit Papiano ](https://www.expedia.ca/Papiano.dx3000377350) - [Visit Passignano sul Trasimeno ](https://www.expedia.ca/Passignano-Sul-Trasimeno.dx181272) - [Visit Old Town Perugia ](https://www.expedia.ca/Perugia-Old-Town-Perugia.dx553248635810303102) - [Visit Ponte d'Oddi ](https://www.expedia.ca/Perugia-Ponte-DOddi.dx553248635976399073) - [Visit Perugia ](https://www.expedia.ca/Perugia.dx2762) - [Visit Petrignano ](https://www.expedia.ca/Petrignano.dx6025586) - [Piazza IV Novembre ](https://www.expedia.ca/Piazza-IV-Novembre-Old-Town-Perugia.d6073770.Vacation-Attraction) - [Visit Poggio Aquilone ](https://www.expedia.ca/Poggio-Aquilone.dx3000026928) - [Visit Ponte Felcino ](https://www.expedia.ca/Ponte-Felcino.dx3000026891) - [Visit Ponte San Giovanni ](https://www.expedia.ca/Ponte-San-Giovanni.dx6055068) - [Province of Perugia Vacations ](https://www.expedia.ca/Province-Of-Perugia.d6046902.Destination-Travel-Guides) - [Visit Province of Perugia ](https://www.expedia.ca/Province-Of-Perugia.dx6046902) - [Visit Rancolfo ](https://www.expedia.ca/Rancolfo.dx3000476761) - [Visit San Martino in Campo ](https://www.expedia.ca/San-Martino-In-Campo.dx6055069) - [Visit Sant'Orfeto ](https://www.expedia.ca/SantOrfeto.dx553248635149812478) - [Visit Santa Maria degli Angeli ](https://www.expedia.ca/Santa-Maria-Degli-Angeli.dx6056295) - [Santa Maria della Misericordia Hospital ](https://www.expedia.ca/Santa-Maria-Della-Misericordia-Hospital-Perugia.d6188142.Vacation-Attraction) - [Visit Soccorso ](https://www.expedia.ca/Soccorso.dx824941938232221696) - [Visit Spina ](https://www.expedia.ca/Spina.dx553248627539495999) - [Umbria Vacations ](https://www.expedia.ca/Umbria.d6048668.Destination-Travel-Guides) - [Visit Umbria ](https://www.expedia.ca/Umbria.dx6048668) - [Convertible Car Rentals in Umbria ](https://www.expedia.ca/Convertible-Car-Rentals-In-Umbria.d6048668-tConvertible.Car-Rental-Destination-Class) - [Car rentals near Umbria ](https://www.expedia.ca/Destinations-In-Umbria.d6048668.Car-Rental-Destinations) - [Dollar Rent A Car Rental Cars in Umbria ](https://www.expedia.ca/Dollar-Rent-A-Car-Destinations-In-Umbria.d6048668-c43.Car-Rental-Destination-Suppliers) - [Europcar Rental Cars in Umbria ](https://www.expedia.ca/Europcar-Destinations-In-Umbria.d6048668-c14.Car-Rental-Destination-Suppliers) - [Full-Size Car Rentals in Province of Perugia ](https://www.expedia.ca/Fullsize-Car-Rentals-In-Province-Of-Perugia.d6046902-tFullsize.Car-Rental-Destination-Class) - [Luxury Car Rentals in Umbria ](https://www.expedia.ca/Luxury-Car-Rentals-In-Umbria.d6048668-tLuxury.Car-Rental-Destination-Class) - [Sports Car Car Rentals in Umbria ](https://www.expedia.ca/Sportscar-Car-Rentals-In-Umbria.d6048668-tSportscar.Car-Rental-Destination-Class) - [Province of Perugia Vacation Rentals ](https://www.expedia.ca/Destinations-In-Province-Of-Perugia.d6046902.Vacation-Rental-Destinations) - [Umbria Vacation Rentals ](https://www.expedia.ca/Destinations-In-Umbria.d6048668.Vacation-Rental-Destinations) - [Things to do in Perugia ](https://www.expedia.ca/Things-To-Do-In-Perugia.d2762.Travel-Guide-Activities) - [Things to do in Umbria ](https://www.expedia.ca/Things-To-Do-In-Umbria.d6048668.Travel-Guide-Activities) - Cities near San Sisto - Places of interest [Perugia](https://expedia.ca/Perugia.dx2762)[Corciano](https://expedia.ca/Corciano.dx6023883) - [Lake Trasimeno ](https://expedia.ca/Lake-Trasimeno-Umbria.d6055082.Vacation-Attraction) - [Basilica of St. Mary of the Angels ](https://expedia.ca/Basilica-Of-St-Mary-Of-The-Angels-Assisi.d6073816.Vacation-Attraction) - [Basilica San Francesco di Assisi ](https://expedia.ca/Basilica-San-Francesco-Di-Assisi-Assisi-Historic-Center.d6195078.Vacation-Attraction) - [Piazza del Comune ](https://expedia.ca/Piazza-Del-Comune-Assisi-Historic-Center.d6073760.Vacation-Attraction) - [Tiber River ](https://expedia.ca/Tiber-River-Marcigliana.d553248621532500472.Vacation-Attraction) - [San Damiano ](https://expedia.ca/San-Damiano-Assisi.d6073796.Vacation-Attraction) - [Via San Francesco ](https://expedia.ca/Via-San-Francesco-Assisi-Historic-Center.d6187886.Vacation-Attraction) - [Santa Maria della Misericordia Hospital ](https://expedia.ca/Santa-Maria-Della-Misericordia-Hospital-Perugia.d6188142.Vacation-Attraction) - [Piazza IV Novembre ](https://expedia.ca/Piazza-IV-Novembre-Old-Town-Perugia.d6073770.Vacation-Attraction) - [Roman Temple of Minerva ](https://expedia.ca/Roman-Temple-Of-Minerva-Assisi-Historic-Center.d6073794.Vacation-Attraction) - [Roman Aqueduct ](https://expedia.ca/Roman-Aqueduct-Old-Town-Perugia.d6188057.Vacation-Attraction) - [Rocca Maggiore ](https://expedia.ca/Rocca-Maggiore-Assisi-Historic-Center.d6073790.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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