Name: Giotto Hotel & Spa
Price range: CA $203
Rating: 8.8

Your San Sisto Vacation

An easy way to experience this interesting city is with a customized San Sisto vacation package. Stay in the neighborhood of San Biagio della Valle, which is good for views, nature and history or go someplace else — our package deals are all about you. Make your trip to San Sisto even more fun by including some sightseeing. Piazza IV Novembre, Rocca Paolina and Basilica San Pietro are some of the major attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to San Sisto to suit your style of travel, whatever that may be.

Top San Sisto Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Hotel Villa Pina

CA $239

per person

Jun 5 - Jun 8

found 1 day ago

Roundtrip flight included

Tirana (TIA) to Ancona (AOI)

7.8/10 Good! (9 reviews)

Hotel Emilia

CA $446

per person

Jun 5 - Jun 8

found 1 day ago

Roundtrip flight included

Tirana (TIA) to Ancona (AOI)

9.2/10 Wonderful! (180 reviews)

Great place with great ocean view! You will like it.

Reviewed on Oct 6, 2025

Hotel Fiorella

CA $293

per person

Jun 5 - Jun 8

found 1 day ago

Roundtrip flight included

Tirana (TIA) to Ancona (AOI)

8.2/10 Very Good! (12 reviews)

Staying at the property allowed us to be near where we needed to be. The room was small but ok. Breakfast terrible and the staff whem checking out were rude and unhelpful

Reviewed on Aug 2, 2025

Hotel Continental

CA $249

per person

Jun 5 - Jun 8

found 1 day ago

Roundtrip flight included

Tirana (TIA) to Ancona (AOI)

7.6/10 Good! (9 reviews)

Terrazza Marconi Hotel & Spamarine

CA $505

per person

Jun 5 - Jun 8

found 1 day ago

Roundtrip flight included

Tirana (TIA) to Ancona (AOI)

9.2/10 Wonderful! (69 reviews)

Right on the ocean with convenient walking to beach and pubs with excellent meals

Reviewed on Sep 21, 2023

Ready to book your vacation to San Sisto?

Choose your dates

San Sisto Hotel Deals

Villa di Piazzano - Small Luxury Hotel of the World

Localita Piazzano, C.P. 6 Cortona AR

CA $994

CA $1,106 total

May 10 - May 11

includes taxes & fees

9.8/10 Exceptional! (229 reviews)

We really enjoyed the hotel, very clean, good atmosphere!!!

Reviewed on Apr 10, 2026

Hotel Sangallo Palace

Via L Masi 9 Perugia PG

Fully refundableReserve now, pay when you stay

CA $211

CA $242 total

Apr 26 - Apr 27

includes taxes & fees

8.8/10 Excellent! (630 reviews)

This is a very nice full service hotel in good location for taking escalators up to the old city. Clean room. Great breakfast.

Reviewed on Mar 10, 2026

Giotto Hotel & Spa

Via Fontebella 41 Assisi PG

Fully refundableReserve now, pay when you stay

CA $203

CA $236 total

Apr 20 - Apr 21

includes taxes & fees

8.8/10 Excellent! (790 reviews)

Great location, very close to St Francis Basilica. We were only there one night, we will go back.

Reviewed on Apr 14, 2026

See all 3,415 properties in San Sisto

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.