What to do in San Sisto

Activities, attractions and tours

San Sisto Attractions

Let Expedia help you experience the best that San Sisto has to offer! If you’re looking for fun itinerary ideas, we can provide you with a list of the top sightseeing attractions, as well as helping you to find unmissable activities. Whether you’re travelling with your family, planning a romantic trip with your loved one, or visiting on business, we’ll make it easy to plan an unforgettable holiday that checks all the boxes.

Activities and Tours

San Sisto is crammed with must-see places to visit and things to do. We can help you decide where to stay, and make it a breeze to explore the surrounding areas with our guides on where to go, what to see and when to see it. No matter how long your stay, it’s easy to find places of interest in San Sisto to make sure that you enjoy your experience to the fullest and don’t miss a thing. Leave the local knowledge to us and leave the hassle behind.

If you’re planning a visit, why not check out our handy guides to places of interest in the area? You can browse lists of things to do, learn about the most popular attractions, and get help with planning the details of your trip. Expedia makes it easy for you to check out all the top sights.

San Sisto Attractions

Expedia has something for everyone, so whether you’re planning to get active on a summer holiday, put a spring in your step with a romantic rendezvous, or pamper yourself with a leisurely winter trip, you’ll find plenty of attractions to keep you entertained. In addition to scheduling local tours, booking reservations and scoring advance event tickets, Expedia makes it easy to book your flight, hotel and rental car in advance, all on one consolidated travel itinerary, making for hassle-free travel and freeing you up to explore the sights of San Sisto.

Looking for things to do can be time consuming, but we can take the hassle out of planning your holiday. Whether you’re looking to get active in the great outdoors, sample the cuisine or catch up with the vibrant local culture, our guides to San Sisto attractions ensure that you’ll have a successful trip, whatever the season.


  • find price illustration

    Explore activities

    Explore thousands of experiences from activities and attractions to day tours and transfer.
  • calendar shield illustration

    Book with ease

    Skip the line- book tickets online in minutes to top attractions with free cancellation on many activities.
  • trophy illustration

    Treat yourself

    Members save % or more when you book activities.

Top places to visit

1. Lake Trasimeno

Lake Trasimeno is one of Umbria’s jewels. Nestled amid rolling countryside, vineyards and olive groves it is both a natural haven and a cultural treasure. Explore the villages dotted along the shoreline and discover their fascinating history and architecture, or simply soak up their peaceful atmosphere.
Learn more
Trasimeno lake panoramic view,Castiglione del lago fortress, Umbria, Italy

2. Basilica of St. Mary of the Angels

The Basilica of Santa Maria degli Angeli is an enormous church that attracts pilgrims from across the globe with its Baroque chapels and Franciscan origin story. Learn about St. Francis of Assisi, who chose to live a life of poverty in the 12th century.
Learn more
Santa Maria degli Angeli which includes a church or cathedral and religious aspects

3. Basilica San Francesco di Assisi

A powerfully affecting site for believers and art-lovers alike, the Papal Basilica of St. Francis of Assisi is the crowning jewel of the town’s UNESCO heritage-listed Franciscan structures. Immense in scale and ambitious in design, the basilica can be seen from miles around and boasts glorious views into the valleys surrounding the town of Assisi. Spend an afternoon exploring the churches, gardens, piazzas and the crypt that houses the elaborate tomb of St. Francis.
Learn more
Papal Basilica of St. Francis of Assisi showing heritage architecture

4. Piazza del Comune

Widely considered one of the best-preserved medieval squares in all of Italy, the Piazza del Comune is the focal point of the town of Assisi. Explore the open-air restaurants, gelatarias and wine bars that surround this pedestrian-only square, giving it a lovely warm atmosphere that attracts tourists and locals. After a long day sightseeing on the hilly streets of Assisi, the piazza is the perfect place to sit back and relax.
Learn more
Piazza del Comune featuring a fountain, a square or plaza and street scenes

5. Basilica of Santa Chiara

Constructed between 1257 and 1265, the Basilica of Santa Chiara is of great historic and spiritual significance. The church is named after St. Clare, a friend and protégé of St. Francis, who founded the Order of Poor Ladies, which still has thousands of members today. Take advantage of the excellent photo opportunities available in the adjoining piazza, from which you have wonderful views of the valleys south of Assisi.
Learn more
Basilica of Santa Chiara featuring farmland, a church or cathedral and landscape views

6. Cathedral of San Rufino

Although less famed than some of the other religious buildings in Assisi, the Cathedral of San Rufino is a site of enormous historic, spiritual and architectural significance. Dedicated to Assisi’s patron saint, Rufinus of Assisi, who converted the town to Christianity in the 3rd century, the Cathedral of San Rufino stands on the ruins of two other religious buildings. Explore the cathedral’s interior, the surrounding piazza and the subterranean crypt to see a diverse array of architectural styles and learn about the importance of the site in the history of the Franciscan Order.
Learn more
Cathedral of San Rufino showing heritage architecture, religious aspects and a church or cathedral

7. Via San Francesco

Wander along Via San Francesco and discover multiple sightseeing destinations located next to one another. Walk along this short road and the alleys branching off it to find a stunning stone church, chapels from different eras of Perugia’s history and a museum of fine arts held in a convent. A charming, grass-covered piazza and medieval stone houses make it one of the prettiest streets in the area.
Learn more
Via San Francesco showing a coastal town, flowers and street scenes

What to do in San Sisto


Discover the most popular places to visit in San Sisto


 

Looking for fun things to do nearby? Check things to do near me to find and book the best things to do, fun activities, and top attractions wherever you happen to be.

 


 

Day trip destinations from San Sisto

Frequently asked questions

Is San Sisto worth visiting?
San Sisto has an interesting mix of attractions, local charm and culture. Whether you're into the outdoors, history or traditional food, there's a lot you'll enjoy here.
How do I spend a day in San Sisto?
After you've checked off top attractions like Citta della Domenica and Castello di Ramazzano, spend some time exploring the retail and food options in San Sisto.
What is the top tourist attraction in San Sisto?
Don't go home without checking out Citta della Domenica, rated the top tourist attraction in San Sisto.
Is three days enough to stay in San Sisto?
Three days will be enough time to check out the leading city sights, like Citta della Domenica, Cathedral of Saint Lorenzo and Teatro Lyrick Assisi. The average stay in San Sisto is three days. If you feel the urge to extend your break, Assisi isn't far away.
Is San Sisto a walkable city?
With exciting neighbourhoods and major sights within walking distance of the city centre, San Sisto is a good destination to see on foot. Enjoy wandering between Citta della Domenica and Cathedral of Saint Lorenzo. Then take a stroll through Old Town Perugia, located 5 kilometres from the centre, and Ferro di Cavallo, which is roughly 2 kilometres away.
What are some activities to do in San Sisto with kids?
Planning what to do in San Sisto with kids is easier than ever. Whether you're getting away with teenagers or toddlers, there are loads of family-friendly tours and attractions to keep them happy here.

What to do in San Sisto for adults?
Whether you're a culture enthusiast, avid foodie or outdoor adventurer, there are plenty of things to do in San Sisto for adults including Cantina Dionigi and Cantine Giorgio Lungarotti.
Are there free things to do in San Sisto?
In San Sisto, Cathedral of Saint Lorenzo is an unmissable spot for anyone wanting to see the city without opening their wallet. Also, stroll around the local neighbourhoods and parks, and ask for tips from a local tour guide. It's an easy way to learn about the best free things to do in San Sisto.