San Antonio Vacation Packages
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Your San Antonio Vacation
From its rich history to its cultural experiences and beyond, there's a whole lot to love about San Antonio. Discover the wonders of this exciting city with a San Antonio vacation package that's tailor-made for you. Metromall Panama is just one of the must-see attractions to add to your sightseeing agenda during a trip to San Antonio. A few clicks is all it takes to craft the ideal San Antonio vacation on Expedia.
Top Holiday Package Deals in San Antonio
Price found within the past 48 hours. Click for updated prices.
Where to stay in San Antonio
Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
José Domingo Espinar
When in José Domingo Espinar, you can plan a visit to Estadio Rommel Fernandez and Metromall Panama, some noteworthy sights in the nearby area.
Rufina Alfaro
1 out of top 10 points of interest in this area
While you're in Rufina Alfaro, take in top sights like Metromall Panama and jump on the metro at San Antonio Station to see more of the city.
Cerro Viento
Shopping and restaurants are notable features of Cerro Viento. You might consider a stop by Metromall Panama while you're exploring the neighborhood.
Belisario Porras
Even though there aren't top sights in Belisario Porras, you can explore the larger area and take in top sights like Estadio Rommel Fernandez. Jump on the metro at Los Andes Station to see more of the city.
Amelia Denis de Icaza
Even though there aren't top sights in Amelia Denis de Icaza, you can explore the larger area and take in top sights like El Dorado Mall. Jump on the metro at Pan de Azúcar Station to see more of the city.
San Antonio Hotel Deals
Courtyard by Marriott Panama Metromall
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
CA $136
CA $149 total
Oct 2 - Oct 3
includes taxes & fees
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
CA $191
CA $210 total
Sep 27 - Sep 28
includes taxes & fees
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
CA $254
CA $280 total
Oct 13 - Oct 14
includes taxes & fees
9/10 Wonderful! (1,015 reviews)
"Loved my stay! The staff was extremely helpful and the amenities were great!"
Reviewed on Sep 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a San Antonio vacation package cost?
Choose from any combination of car rentals, flights and hotels, and you can be vacationing in San Antonio from just CA $1,164. And the more you bundle, the more cash you save. The vacation of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio vacation packages promise plenty of savings for the savvy traveler. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotel options across the globe to pick from. Whatever your budget or style, there's a vacation package that's perfect for you.
Where should I stay in San Antonio?
If you're interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It's one of the best attractions in this neighborhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio's most popular properties. Lock in a room here and you'll slumber peacefully knowing you're in capable hands.
How far in advance should I book my San Antonio vacation?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can't see your preferred air carrier, or you've left things to the last minute, don't stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that's right for you. Vacationing for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you've made your booking. Our vacation packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia vacation package?
Yes — that's the beauty of an Expedia vacation package. You're in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio vacation package?
We totally get it — unexpected stuff happens. If you've booked a San Antonio vacation package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.
Things to do
Panama Canal: The Most Complete Wildlife Experience
CA $66
per adult
96% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
CA $58
per adult
100% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
CA $201
per adult
98% of travellers recommend
Explore a world of travel with Expedia
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- Flights from Calgary (YYC) to Panama City (PTY)
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- Flights from Kingston (KIN) to Panama City (PTY)
- Flights from Port-au-Prince (PAP) to Panama City (PTY)
- Flights from Tampa (TPA) to Panama City (PTY)
- Flights from Edmonton (YEG) to Panama City (PTY)
- Flights from Detroit (DTW) to Panama City (PTY)
- Flights from Saskatoon (YXE) to Panama City (PTY)
- Flights from San José (SJO) to Panama City (PTY)
- Flights from Ottawa (YOW) to Panama City (PTY)
- Flights from Liberia (LIR) to Panama City (PTY)
- Flights from Medellín (MDE) to Panama City (PTY)
- Flights from Buenos Aires (EZE) to Panama City (PTY)
- Flights from Huatulco (HUX) to Panama City (PTY)
- Flights from New York (JFK) to Panama City (PTY)
- Flights from Comox (YQQ) to Panama City (PTY)
- Flights from Kamloops (YKA) to Panama City (PTY)
- Flights from Québec (YQB) to Panama City (PTY)
- Flights from Moncton (YQM) to Panama City (PTY)
- Flights from Atlanta (ATL) to Panama City (PTY)
- Flights from Grande Prairie (YQU) to Panama City (PTY)
- Flights from Lima (LIM) to Panama City (PTY)
- Flights from Saint John (YSJ) to Panama City (PTY)
- Flights from Georgetown (GEO) to Panama City (PTY)
- Flights from Santo Domingo (SDQ) to Panama City (PTY)
- Flights from San Salvador (SAL) to Panama City (PTY)
- Flights from Port of Spain (POS) to Panama City (PTY)
- Flights from San Francisco (SFO) to Panama City (PTY)
- Flights from Toronto (YTO) to Panama City (PTY)
- Flights from St. John's (YYT) to Panama City (PTY)
- Flights from Fredericton (YFC) to Panama City (PTY)
- Flights from Rio Hato (RIH) to Panama City (PTY)
- Flights from Thunder Bay (YQT) to Panama City (PTY)
- Flights from Buffalo (BUF) to Panama City (PTY)
- Flights from Bridgetown (BGI) to Panama City (PTY)
- Flights from Guayaquil (GYE) to Panama City (PTY)
- Flights from Phoenix (PHX) to Panama City (PTY)
- Flights from Miami (MIA) to Panama City (PTY)
- Flights from London (LHR) to Panama City (PTY)
- Flights from Chicago (ORD) to Panama City (PTY)
- Flights from Spokane (GEG) to Panama City (PTY)
- Flights from Nanaimo (YCD) to Panama City (PTY)
- Flights from Cancun (CUN) to Panama City (PTY)
- Flights from São Paulo (GRU) to Panama City (PTY)
- Flights from Fort Lauderdale (FLL) to Panama City (PTY)
- Flights from Halifax (YHZ) to Panama City (PTY)
- Flights from Kelowna (YLW) to Panama City (PTY)
- Flights from Los Angeles (LAX) to Panama City (PTY)
- Flights from Willemstad (CUR) to Panama City (PTY)
- Flights from Caracas (CCS) to Panama City (PTY)
- Flights from Houston (IAH) to Panama City (PTY)
- Flights from Managua (MGA) to Panama City (PTY)
- Flights from Hamilton (YHM) to Panama City (PTY)
- Flights from Windsor (YQG) to Panama City (PTY)
- Flights from Regina (YQR) to Panama City (PTY)
- Flights from Las Vegas (LAS) to Panama City (PTY)
- Flights from Vancouver (YVR) to Panama City (PTY)
- Copa Toronto (YYZ) to Panama City (PTY) flights
- Flights from Quito (UIO) to Panama City (PTY)
- Flights from Cartagena (CTG) to Panama City (PTY)
- Flights from Seattle (SEA) to Panama City (PTY)
- Flights from Punta Cana (PUJ) to Panama City (PTY)
- Flights from Bogotá (BOG) to Panama City (PTY)
- Flights from Mexico City (MEX) to Panama City (PTY)
- Flights from Belo Horizonte (CNF) to Panama City (PTY)
- Flights from Prince George (YXS) to Panama City (PTY)
- Flights from San José del Cabo (SJD) to Panama City (PTY)
- Flights from Nassau (NAS) to Panama City (PTY)
- Copa Montreal (YUL) to Panama City (PTY) flights
- Flights from Orlando (MCO) to Panama City (PTY)
- Flights from Victoria (YYJ) to Panama City (PTY)
- Flights from Winnipeg (YWG) to Panama City (PTY)
- Flights from Guatemala City (GUA) to Panama City (PTY)
- Flights from Toronto (YYZ) to Panama City (PTY)
- Flights from Charlottetown Alexander B. Campbell Airport (YYG) to Panama City (PTY)
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.