Title: CA $452 Cheap Flights from Detroit (DTW) to Panama City (PTY) - Expedia.ca ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # CA $452 Cheap Flights from Detroit (DTW) to Panama City (PTY) [View CA $452 flight on Tue, Apr 28, 2026](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:DTW,to:PTY,departure:28/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:451.67&airProductToken=AQpnCjIIwYIBEgQxMDIwGOO0ASCMAijpxYsDMKDHiwM4QkAAWAFqBUJBU0lDcghRTlg5QUhCWgoxCMGCARIDNDExGIwCIO_EASjNx4sDMIvJiwM4QkABWAFqBUJBU0lDcghRTlg5QUhCWhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to Tocumen Intl. Airport (PTY) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.ca/Flights-Search?leg1=from:dtw,to:pty,departure:15/11/2025TANYT&leg2=from:pty,to:dtw,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:dtw,to:pty,departure:15/11/2025TANYT&leg2=from:pty,to:dtw,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:dtw,to:pty,departure:15/11/2025TANYT&leg2=from:pty,to:dtw,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.ca/Flights-Search?leg1=from:dtw,to:pty,departure:15/11/2025TANYT&leg2=from:pty,to:dtw,departure:22/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheap flights from Detroit (DTW) to Panama City (PTY) Prices were available within the past 7 days and start at CA $452 for one-way flights and CA $821 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Apr 20 - Wed, Apr 29 DTW Detroit PTY Panama City CA $821 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:20/04/2026TANYT&leg2=from:PTY,to:DTW,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:820.97&airProductToken=AQpwCjYIxJgBEgQyMjk0GOO0ASDgXCiR8ooDMI7zigM4RUAAWAFqCU1BSU5CQVNJQ3IIVk5YWTdOQloKNgjEmAESBDE3NTkY4Fwg78QBKNj4igMw0_qKAzhFQAFYAWoJTUFJTkJBU0lDcghWTlhZN05CWgpvCjYIxJgBEgQxNzU4GO_EASDgXCio1YsDMKzXiwM4RUAAWAFqCU1BSU5CQVNJQ3IIVk5YWTdOQloKNQjEmAESAzg1MhjgXCDjtAEouOKLAzCv44sDOEVAAVgBaglNQUlOQkFTSUNyCFZOWFk3TkJaEgoIARABGAEqAkRMGAEiBAgBEAEoAigDKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, Mar 11 - Mon, Mar 23 DTW Detroit PTY Panama City CA $823 Roundtrip found 7 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:11/03/2026TANYT&leg2=from:PTY,to:DTW,departure:23/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:822.50&airProductToken=AQpGCiEI1YIBEgQyMDM0GOO0ASCIOCioqocDMPSrhwM4VEAAWAEKIQjVggESBDE5MTYYiDgg78QBKKashwMw5a2HAzhUQAFYAQpHCiEI1YIBEgM3MjcY78QBIMSNASjmsogDMOC1iAM4VEAAWAEKIgjVggESBDM1ODYYxI0BIOO0ASjktogDMO23iAM4VEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Fri, Mar 6 - Fri, Mar 20 DTW Detroit PTY Panama City CA $824 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:06/03/2026TANYT&leg2=from:PTY,to:DTW,departure:20/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:823.49&airProductToken=AQpnCjIIwYIBEgQxMDIwGOO0ASCMAijb8YYDMLDzhgM4QkAAWAFqBUJBU0lDcghRTlg5SUhCWgoxCMGCARIDMzE5GIwCIO_EASjv84YDMK31hgM4QkABWAFqBUJBU0lDcghRTlg5SUhCWgqbAQoyCMGCARIEMjk2NBjvxAEgjAIoipOIAzDDlIgDOEJAAFgBagVCQVNJQ3IIUU5YOUlIQloKMQjBggESBDEzODkYjAIgywEo6JWIAzCll4gDOEJAAVgBagVCQVNJQ3IIUU5YOUlIQloKMgjBggESBDQ0NTAYywEg47QBKNWbiAMw15yIAzhCQAFYAWoFQkFTSUNyCFFOWDlJSEJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Tue, Apr 21 - Wed, Apr 29 DTW Detroit PTY Panama City CA $824 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:21/04/2026TANYT&leg2=from:PTY,to:DTW,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:823.50&airProductToken=AQpGCiEIxJgBEgQxNjExGOO0ASDgXCjS94oDMNH4igM4RUAAWAEKIQjEmAESBDE3NTkY4Fwg78QBKJT5igMw0_qKAzhFQAFYAQpGCiEIxJgBEgQxNzU4GO_EASDgXCio1YsDMOjXiwM4RUAAWAEKIQjEmAESBDI5NDAY4Fwg47QBKJLZiwMwitqLAzhFQAFYARIKCAEQARgBKgJETBgBIgQIARABKAQwAQ) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sun, May 3 - Mon, May 18 DTW Detroit PTY Panama City CA $825 Roundtrip found 5 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:03/05/2026TANYT&leg2=from:PTY,to:DTW,departure:18/05/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:824.60&airProductToken=AQpGCiEIxJgBEgQxNjUzGOO0ASDgXCjRhYwDMNCGjAM4RUAAWAEKIQjEmAESBDE3NTkY4Fwg78QBKLSLjAMw84yMAzhFQAFYAQpGCiEIxJgBEgQxNzU4GO_EASDgXCiIq40DMMitjQM4RUAAWAEKIQjEmAESBDI5NDAY4Fwg47QBKPKujQMw6q-NAzhFQAFYARIKCAEQARgBKgJETBgBIgQIARABKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Apr 20 - Wed, Apr 29 DTW Detroit PTY Panama City CA $849 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:20/04/2026TANYT&leg2=from:PTY,to:DTW,departure:29/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:848.97&airProductToken=AQpnCjIIwYIBEgQxMDIwGOO0ASCMAijp64oDMKDtigM4QkAAWAFqBUJBU0lDcghRTlc5SUhCWgoxCMGCARIDNDExGIwCIO_EASjN7YoDMIvvigM4QkABWAFqBUJBU0lDcghRTlc5SUhCWgpoCjIIwYIBEgQyOTY0GO_EASCMAiiP1YsDMMPWiwM4QkAAWAFqBUJBU0lDcghRTlg5SUhCWgoyCMGCARIEMjY0ORiMAiDjtAEooteLAzDl2IsDOEJAAVgBagVCQVNJQ3IIUU5YOUlIQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Feb 2 - Fri, Feb 13 DTW Detroit PTY Panama City CA $852 Roundtrip found 3 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:02/02/2026TANYT&leg2=from:PTY,to:DTW,departure:13/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:851.59&airProductToken=AQpnCjIIwYIBEgQxMDIwGOO0ASCMAijWiYQDMKqLhAM4QkAAWAFqBUJBU0lDcghRTlc5SUhCWgoxCMGCARIDMzE5GIwCIO_EASjzi4QDMLONhAM4QkABWAFqBUJBU0lDcghRTlc5SUhCWgqdAQoyCMGCARIEMjk2NBjvxAEgjAIo24mFAzCki4UDOEJAAFgBagVCQVNJQ3IIUU5YOUlIQloKMgjBggESBDE1NjUYjAIgo7EBKJSNhQMw5I6FAzhCQAFYAWoFQkFTSUNyCFFOWDlJSEJaCjMIwYIBEgQyMzc0GKOxASDjtAEo7JGFAzCLk4UDOEJAAVgBagVCQVNJQ3IIUU5YOUlIQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, Mar 11 - Sat, Mar 21 DTW Detroit PTY Panama City CA $858 Roundtrip found 7 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:11/03/2026TANYT&leg2=from:PTY,to:DTW,departure:21/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:857.50&airProductToken=AQpGCiEI1YIBEgQyMDM0GOO0ASCIOCioqocDMPSrhwM4VEAAWAEKIQjVggESBDE5MTYYiDgg78QBKKashwMw5a2HAzhUQAFYAQpHCiEI1YIBEgM3MjcY78QBIMSNASimnIgDMKCfiAM4VEAAWAEKIgjVggESBDM1ODYYxI0BIOO0ASikoIgDMK2hiAM4VEABWAESCggBEAEYASoCVUEYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Feb 2 - Fri, Feb 13 DTW Detroit PTY Panama City CA $859 Roundtrip found 3 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:02/02/2026TANYT&leg2=from:PTY,to:DTW,departure:13/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:858.59&airProductToken=AQpwCjYIxJgBEgQxMjI4GOO0ASDgXCjxjIQDMO2NhAM4RUAAWAFqCU1BSU5CQVNJQ3IIVk5YWTdOQloKNgjEmAESBDE3NTkY4Fwg78QBKPaWhAMw75iEAzhFQAFYAWoJTUFJTkJBU0lDcghWTlhZN05CWgpwCjYIxJgBEgQxNzU4GO_EASDgXCiLioUDMJGMhQM4RUAAWAFqCU1BSU5CQVNJQ3IIVk5XWTdOQloKNgjEmAESBDE0NzgY4Fwg47QBKNCWhQMwyZeFAzhFQAFYAWoJTUFJTkJBU0lDcghWTldZN05CWhIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Mon, Dec 29 - Sat, Jan 17 DTW Detroit PTY Panama City CA $1,050 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DTW,to:PTY,departure:29/12/2025TANYT&leg2=from:PTY,to:DTW,departure:17/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1049.10&airProductToken=AQpFCiEIw5oBEgQxODA2GOO0ASCuHCjUgYEDMLuCgQM4TEAAWAEKIAjDmgESAzIyORiuHCDvxAEot4SBAzD_hoEDOExAAVgBCkUKIAjDmgESAzQwNBjvxAEgiBgo0d2CAzDt34IDOExAAFgBCiEIw5oBEgQxMjgxGIgYIOO0ASil4oIDMIvjggM4TEABWAESCggBEAEYASoCQ00YASIECAEQASgEMAE) ## Find the cheapest month to fly from Detroit (DTW) to Panama City (PTY) ### October is typically the cheapest month to fly From CA $706 - CA $1,636 per traveller. ## Alternative airports near Panama City Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.ca/Flights-Search?leg1=from:DTW,to:PTY,departure:15/11/2025TANYT&leg2=from:PTY,to:DTW,departure:03/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) PTY Tocumen Intl. Cheapest 16 min [Flights from CA $1,121](https://www.expedia.ca/Flights-Search?leg1=from:DTW,to:PTY,departure:15/11/2025TANYT&leg2=from:PTY,to:DTW,departure:03/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) Flight from Detroit to Panama City (DTW - PTY) route information | Origin airport | Detroit Metropolitan Wayne County | | --- | --- | | Destination airport | Tocumen Intl. | | Airlines serving | American Airlines, Copa, Delta, United | | Roundtrip price | CA $821 | | Distance | 3685 km | ## Detroit to Tocumen Flights **The easy way to book your flights from Detroit to Panama City**  With Expedia, it’s simple to find and book flights to Panama City from Detroit whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Tocumen Intl., too.   Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Detroit to Panama City today, tomorrow, or this week.   **Save dollars with cheap flights from Detroit Metropolitan Wayne County, DTW to Tocumen Intl., PTY**  Sort your search results by price to find great deals on your flight from Detroit to Panama City—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Panama City from Detroit currently is just CA $821 rising to CA $1,059.   Here are more money-saving tips:  - Fly in April when flight prices are normally at their lowest  - Book about a month to 6 weeks before you travel for the best prices to Panama City   - Avoid peak season and weekends when flights can cost more - Early morning and late-night flights are sometimes cheaper, so try varying your travel times  - One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!  **Reasons to choose Expedia for your flight to Panama City from Detroit**  Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Panama City with Expedia today. ## Frequently asked questions ### How much is a flight from Detroit Metropolitan Wayne County Airport (DTW) to Tocumen Intl. Airport (PTY)? > Start packing your bags, because round-trip flights between DTW and PTY start from CA $821. That's based on fares advertised within the last 7 days on Expedia for flights departing within the next year. Prices can increase quickly, so book now to nab the best deal. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Metro Airport to Tocumen Intl. Airport (PTY)? > We get that life can throw the odd curveball, so we've made it as hassle-free as possible for you to cancel your trip online. Just visit the [Customer Service Portal](https://www.expedia.ca/helpcenter) and follow the instructions. ### How do I find cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to PTY that have flexible change policies? > Many airlines will allow you to move your flight at no extra charge. All you pay is any additional cost for the new flight. When looking for DTW to Panama Airport flights, you'll find a "No change fees" filter for you to pick. ### How many hours is the flight from DTW to PTY? > To survive the 11 hours and 27 minutes flight time between Detroit Metro Airport and Panama Airport, it's wise to come prepared. A smartphone filled with your favourite shows is a fantastic start. ### How far is the flight from Detroit Metropolitan Wayne County Airport (DTW) to Tocumen Intl. Airport (PTY)? > The flying distance between Detroit Metro Airport (DTW) and Panama Airport (PTY) is 3,700 kilometres. Listen to your favourite tunes or get stuck into a book and the journey will whiz by. ### Which airlines fly direct from Detroit Metro Airport to Panama Airport? > Unfortunately, there aren't any airlines that fly direct between Detroit Metropolitan Wayne County Airport (DTW) and PTY. You'll have to book a flight with at least one stop. ### Are Metro Airport to Tocumen Intl. Airport (PTY) flight tickets cheaper when they're purchased at the last minute? > Booking last minute from Detroit Metro Airport to Panama Airport can be hit-or-miss. You might be lucky and score a bargain, but then again, you could miss out altogether! If you'd rather start your travel planning early, Expedia compares flight deals up to 12 months in advance. Just bear in mind that not all airlines issue their prices that far in advance. Our top tip? Check back often as updates are made regularly. ## Explore a world of travel with Expedia - Flights ### Flights - [Flights from Delta to Panama City](https://www.expedia.ca/lp/flights/10564/2897/delta-to-panama-city) - [Flights from Kitchener to Panama City](https://www.expedia.ca/lp/flights/10579/2897/kitchener-to-panama-city) - [Flights from San Carlos to Panama City](https://www.expedia.ca/lp/flights/10834/2897/san-carlos-to-panama-city) - [Flights from Gore to Panama City](https://www.expedia.ca/lp/flights/1365/2897/gore-to-panama-city) - [Flights from Isles of Scilly to Panama City](https://www.expedia.ca/lp/flights/1634/2897/isles-of-scilly-to-panama-city) - [Flights from Inverell to Panama City](https://www.expedia.ca/lp/flights/1648/2897/inverell-to-panama-city) - [Flights from Vieux Fort to Panama City](https://www.expedia.ca/lp/flights/178203/2897/vieux-fort-to-panama-city) - [Flights from Cairo to Panama City](https://www.expedia.ca/lp/flights/178243/2897/cairo-to-panama-city) - [Flights from Ho Chi Minh City to Panama City](https://www.expedia.ca/lp/flights/178262/2897/ho-chi-minh-city-to-panama-city) - [Flights from Istanbul to Panama City](https://www.expedia.ca/lp/flights/178267/2897/istanbul-to-panama-city) - [Flights from London to Panama City](https://www.expedia.ca/lp/flights/178279/2897/london-to-panama-city) - [Flights from Rio de Janeiro to Panama City](https://www.expedia.ca/lp/flights/178301/2897/rio-de-janeiro-to-panama-city) - [Flights from Toronto to Panama City](https://www.expedia.ca/lp/flights/178314/2897/toronto-to-panama-city) - [Flights from Vancouver to Panama City](https://www.expedia.ca/lp/flights/178315/2897/vancouver-to-panama-city) - [Flights from Washington to Panama City](https://www.expedia.ca/lp/flights/178318/2897/washington-to-panama-city) - [Flights from Tokyo to Panama City](https://www.expedia.ca/lp/flights/179900/2897/tokyo-to-panama-city) - [Flights from Mazatlán to Panama City](https://www.expedia.ca/lp/flights/180011/2897/mazatlan-to-panama-city) - [Flights from Tel Aviv to Panama City](https://www.expedia.ca/lp/flights/180031/2897/tel-aviv-to-panama-city) - [Flights from Cabo San Lucas to Panama City](https://www.expedia.ca/lp/flights/180032/2897/cabo-san-lucas-to-panama-city) - [Flights from Portland to Panama City](https://www.expedia.ca/lp/flights/181420/2897/portland-to-panama-city) - [Flights from Hondarribia to Panama City](https://www.expedia.ca/lp/flights/182329/2897/hondarribia-to-panama-city) - [Flights from Loreto to Panama City](https://www.expedia.ca/lp/flights/2152/2897/loreto-to-panama-city) - [Flights from Laverton to Panama City](https://www.expedia.ca/lp/flights/2171/2897/laverton-to-panama-city) - [Flights from Mount Vernon to Panama City](https://www.expedia.ca/lp/flights/2463/2897/mount-vernon-to-panama-city) - [Flights from Mandera to Panama City](https://www.expedia.ca/lp/flights/2536/2897/mandera-to-panama-city) - [Flights from Nosara to Panama City](https://www.expedia.ca/lp/flights/2585/2897/nosara-to-panama-city) - [Flights from Nadym to Panama City](https://www.expedia.ca/lp/flights/2625/2897/nadym-to-panama-city) - [Flights from Oaxaca to Panama City](https://www.expedia.ca/lp/flights/2631/2897/oaxaca-to-panama-city) - [Flights from Pereira to Panama City](https://www.expedia.ca/lp/flights/2763/2897/pereira-to-panama-city) - [Flights from Tremuson to Panama City](https://www.expedia.ca/lp/flights/3000035007/2897/tremuson-to-panama-city) - [Flights from Denny Island to Panama City](https://www.expedia.ca/lp/flights/3000045600/2897/denny-island-to-panama-city) - [Flights from Rimini to Panama City](https://www.expedia.ca/lp/flights/3010/2897/rimini-to-panama-city) - [Flights from San Diego to Panama City](https://www.expedia.ca/lp/flights/3073/2897/san-diego-to-panama-city) - [Flights from Singapore to Panama City](https://www.expedia.ca/lp/flights/3168/2897/singapore-to-panama-city) - [Flights from San Juan to Panama City](https://www.expedia.ca/lp/flights/3179/2897/san-juan-to-panama-city) - [Flights from Aracaju to Panama City](https://www.expedia.ca/lp/flights/338/2897/aracaju-to-panama-city) - [Flights from Torreón to Panama City](https://www.expedia.ca/lp/flights/3527/2897/torreon-to-panama-city) - [Flights from Trujillo to Panama City](https://www.expedia.ca/lp/flights/3537/2897/trujillo-to-panama-city) - [Flights from Thiruvananthapuram to Panama City](https://www.expedia.ca/lp/flights/3538/2897/thiruvananthapuram-to-panama-city) - [Flights from Tsumeb to Panama City](https://www.expedia.ca/lp/flights/3541/2897/tsumeb-to-panama-city) - [Flights from Ube to Panama City](https://www.expedia.ca/lp/flights/3603/2897/ube-to-panama-city) - [Flights from Useless Loop to Panama City](https://www.expedia.ca/lp/flights/3656/2897/useless-loop-to-panama-city) - [Flights from Kelowna to Panama City](https://www.expedia.ca/lp/flights/3997/2897/kelowna-to-panama-city) - [Flights from Fort McMurray to Panama City](https://www.expedia.ca/lp/flights/4001/2897/fort-mcmurray-to-panama-city) - [Flights from London to Panama City](https://www.expedia.ca/lp/flights/4127/2897/london-to-panama-city) - [Flights from Darlington to Panama City](https://www.expedia.ca/lp/flights/4619/2897/darlington-to-panama-city) - [Flights from Cobungra to Panama City](https://www.expedia.ca/lp/flights/553248634384055620/2897/cobungra-to-panama-city) - [Flights from Cosoleacaque to Panama City](https://www.expedia.ca/lp/flights/553248635640637058/2897/cosoleacaque-to-panama-city) - [Flights from Penukonda to Panama City](https://www.expedia.ca/lp/flights/553248635939584775/2897/penukonda-to-panama-city) - [Flights from Mihail Kogălniceanu to Panama City](https://www.expedia.ca/lp/flights/553248635943689169/2897/mihail-kogalniceanu-to-panama-city) - [Flights from Bikini to Panama City](https://www.expedia.ca/lp/flights/581/2897/bikini-to-panama-city) - [Flights from Pensacola to Panama City](https://www.expedia.ca/lp/flights/6023331/2897/pensacola-to-panama-city) - [Flights from Bocas del Toro to Panama City](https://www.expedia.ca/lp/flights/6023445/2897/bocas-del-toro-to-panama-city) - [Flights from São Luís to Panama City](https://www.expedia.ca/lp/flights/6023853/2897/sao-luis-to-panama-city) - [Flights from Freeport to Panama City](https://www.expedia.ca/lp/flights/602484/2897/freeport-to-panama-city) - [Flights from Buffalo to Panama City](https://www.expedia.ca/lp/flights/602674/2897/buffalo-to-panama-city) - [Flights from Montgomery to Panama City](https://www.expedia.ca/lp/flights/602983/2897/montgomery-to-panama-city) - [Flights from Fort Wayne to Panama City](https://www.expedia.ca/lp/flights/603000/2897/fort-wayne-to-panama-city) - [Flights from Biloxi to Panama City](https://www.expedia.ca/lp/flights/603259/2897/biloxi-to-panama-city) - [Flights from Annapolis to Panama City](https://www.expedia.ca/lp/flights/6034082/2897/annapolis-to-panama-city) - [Flights from Saint-Louis to Panama City](https://www.expedia.ca/lp/flights/6035020/2897/saint-louis-to-panama-city) - [Flights from Liverpool to Panama City](https://www.expedia.ca/lp/flights/6046241/2897/liverpool-to-panama-city) - [Flights from Phuket to Panama City](https://www.expedia.ca/lp/flights/6046393/2897/phuket-to-panama-city) - [Flights from Lafayette to Panama City](https://www.expedia.ca/lp/flights/6047257/2897/lafayette-to-panama-city) - [Flights from Bremen to Panama City](https://www.expedia.ca/lp/flights/6050592/2897/bremen-to-panama-city) - [Flights from Santa María Huatulco to Panama City](https://www.expedia.ca/lp/flights/6051926/2897/santa-maria-huatulco-to-panama-city) - [Flights from Saint-Jacques-de-la-Lande to Panama City](https://www.expedia.ca/lp/flights/6052612/2897/saint-jacques-de-la-lande-to-panama-city) - [Flights from Tocumen to Panama City](https://www.expedia.ca/lp/flights/6053184/2897/tocumen-to-panama-city) - [Flights from Matsumoto to Panama City](https://www.expedia.ca/lp/flights/6053699/2897/matsumoto-to-panama-city) - [Flights from San Salvador to Panama City](https://www.expedia.ca/lp/flights/6053734/2897/san-salvador-to-panama-city) - [Flights from Santa Cruz to Panama City](https://www.expedia.ca/lp/flights/6053940/2897/santa-cruz-to-panama-city) - [Flights from Cordoba to Panama City](https://www.expedia.ca/lp/flights/6054205/2897/cordoba-to-panama-city) - [Flights from Rehoboth Beach to Panama City](https://www.expedia.ca/lp/flights/6055674/2897/rehoboth-beach-to-panama-city) - [Flights from Waldorf to Panama City](https://www.expedia.ca/lp/flights/6057464/2897/waldorf-to-panama-city) - [Flights from Chatham-Kent to Panama City](https://www.expedia.ca/lp/flights/6057866/2897/chatham-kent-to-panama-city) - [Flights from El Dorado to Panama City](https://www.expedia.ca/lp/flights/6058427/2897/el-dorado-to-panama-city) - [Flights from Cerklje na Gorenjskem to Panama City](https://www.expedia.ca/lp/flights/6060741/2897/cerklje-na-gorenjskem-to-panama-city) - [Flights from Palmas to Panama City](https://www.expedia.ca/lp/flights/6084552/2897/palmas-to-panama-city) - [Flights from Jamnagar to Panama City](https://www.expedia.ca/lp/flights/6135723/2897/jamnagar-to-panama-city) - [Flights from Shiojiri to Panama City](https://www.expedia.ca/lp/flights/6140112/2897/shiojiri-to-panama-city) - [Flights from Armenia to Panama City](https://www.expedia.ca/lp/flights/6140801/2897/armenia-to-panama-city) - [Flights from Dover Air Force Base to Panama City](https://www.expedia.ca/lp/flights/6141439/2897/dover-air-force-base-to-panama-city) - [Flights from Beirut to Panama City](https://www.expedia.ca/lp/flights/6144605/2897/beirut-to-panama-city) - [Flights from Hoersching to Panama City](https://www.expedia.ca/lp/flights/6155864/2897/hoersching-to-panama-city) - [Flights from San Miguel to Panama City](https://www.expedia.ca/lp/flights/6336629/2897/san-miguel-to-panama-city) - [Flights from Beaver Falls to Panama City](https://www.expedia.ca/lp/flights/6342/2897/beaver-falls-to-panama-city) - [Flights from Elmas to Panama City](https://www.expedia.ca/lp/flights/6345537/2897/elmas-to-panama-city) - [Flights from Bari to Panama City](https://www.expedia.ca/lp/flights/680/2897/bari-to-panama-city) - [Flights from Drummond Island to Panama City](https://www.expedia.ca/lp/flights/6901/2897/drummond-island-to-panama-city) - [Flights from Iamalele to Panama City](https://www.expedia.ca/lp/flights/7900/2897/iamalele-to-panama-city) - [Flights from Cordova to Panama City](https://www.expedia.ca/lp/flights/799/2897/cordova-to-panama-city) - [Flights from Kanab to Panama City](https://www.expedia.ca/lp/flights/8320/2897/kanab-to-panama-city) - [Flights from Key Largo to Panama City](https://www.expedia.ca/lp/flights/8369/2897/key-largo-to-panama-city) - [Flights from Cali to Panama City](https://www.expedia.ca/lp/flights/863/2897/cali-to-panama-city) - [Flights from Marble Bar to Panama City](https://www.expedia.ca/lp/flights/8704/2897/marble-bar-to-panama-city) - [Flights from Michigan City to Panama City](https://www.expedia.ca/lp/flights/8727/2897/michigan-city-to-panama-city) - [Flights from Milford to Panama City](https://www.expedia.ca/lp/flights/8762/2897/milford-to-panama-city) - [Flights from Andrezieux-Boutheon to Panama City](https://www.expedia.ca/lp/flights/9099/2897/andrezieux-boutheon-to-panama-city) - [Flights from Cooktown to Panama City](https://www.expedia.ca/lp/flights/929/2897/cooktown-to-panama-city) - [Flights from Salinas to Panama City](https://www.expedia.ca/lp/flights/9904/2897/salinas-to-panama-city) \*Available to Expedia members.