Find a Bed and Breakfast in Pamplico from CA $75

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Pamplico

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

1. The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.6 out of 10, Exceptional, (1,003 reviews)
"Great stay!!"
United States
Paige
The price is CA $155
CA $173 total
includes taxes & fees
Dec 8 - Dec 9
The Inn at the Crossroads
A spacious lobby with a chandelier, seating area, and a reception desk.

2. Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.2 out of 10, Good, (191 reviews)
"Not the best hotel. Bathroom was dirty."
United States
Vajannise
The price is CA $119
CA $134 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn & Suites Lake City
A spacious lobby with a large seating area, a decorative ceiling light, and a view of the outdoors.

3. Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (268 reviews)
"I loved everything. Room was clean and smelled amazing"
United States
BRIANNA
The price is CA $137
CA $153 total
includes taxes & fees
Nov 23 - Nov 24
Days Inn by Wyndham Lake City
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

4. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,496 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
The price is CA $127
CA $142 total
includes taxes & fees
Nov 15 - Nov 16
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,384 reviews)
"Comfortable beds and clean environments."
United States
Steven
The price is CA $142
CA $159 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn & Suites Florence Center Area
A spacious lobby with a checkered floor, a reception desk, and a chandelier.

6. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,755 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
The price is CA $85
CA $95 total
includes taxes & fees
Nov 8 - Nov 9
Howard Johnson by Wyndham Florence
A Holiday Inn Express & Suites hotel with a covered entrance, multiple windows, and a parking lot.

7. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,000 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is CA $172
CA $207 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A breakfast buffet with multiple serving dishes and a coffee station by a window with a view of trees.

8. Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (432 reviews)
"Staff was very friendly and helpful."
United States
Willie
The price is CA $108
CA $118 total
includes taxes & fees
Nov 29 - Nov 30
Quality Inn Mullins - Marion
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

9. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very good, (353 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
The price is CA $136
CA $160 total
includes taxes & fees
Nov 15 - Nov 16
Spark by Hilton Florence North I-95, SC
A restaurant with brick walls, framed awards, and a bar area.

10. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (659 reviews)
"The house keeping people"
United States
WILLIE
The price is CA $194
CA $218 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Florence, Tapestry Collection by Hilton
A modern living room with a sectional sofa, a coffee table, and a flat-screen TV mounted on the wall.

11. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.2 out of 10, Good, (1,003 reviews)
"Great and affordable stay"
United States
Shawn
The price is CA $75
CA $84 total
includes taxes & fees
Nov 8 - Nov 9
Super 8 by Wyndham Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (924 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
The price is CA $154
CA $172 total
includes taxes & fees
Nov 8 - Nov 9
TownePlace Suites by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.

13. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (664 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is CA $166
CA $185 total
includes taxes & fees
Nov 11 - Nov 12
Fairfield Inn & Suites by Marriott Florence I-20
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

14. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,001 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
The price is CA $160
CA $179 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn & Suites Florence Center
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

15. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,001 reviews)
"Great hotel and staff"
United States
Margarita
The price is CA $154
CA $180 total
includes taxes & fees
Nov 15 - Nov 16
Tru by Hilton Florence I-95
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

16. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,456 reviews)
"Close to the restaurants and shopping."
United States
Brenda
The price is CA $127
CA $143 total
includes taxes & fees
Nov 9 - Nov 10
La Quinta Inn & Suites by Wyndham Florence
A Holiday Inn Express & Suites building with a modern design, featuring a prominent entrance with a covered walkway and stone pillars.

17. Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (660 reviews)
"Very nice facility and staff."
United States
Carey
The price is CA $133
CA $145 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express & Suites Latta by IHG
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

18. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.4 out of 10, Very good, (422 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is CA $125
CA $140 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn & Suites Florence Civic Center
A Days Inn hotel with a modern design, featuring a large sign, a covered outdoor area, and well-maintained landscaping.

19. Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.6 out of 10, (1,001 reviews)
"Excelente"
United States
Edgar
The price is CA $77
CA $87 total
includes taxes & fees
Nov 25 - Nov 26
Days Inn by Wyndham Florence/I-95 North
A dining area with a wooden table and bench, a dark wooden dresser, and two wall-mounted paintings.

20. Peaceful Retreat at Crawford Farms – Quiet and Comfortable for Work or Relaxing.

Peaceful Retreat at Crawford Farms – Quiet and Comfortable for Work or Relaxing.
Marion
9.0 out of 10, Wonderful, (2 reviews)
"Quiet, cozy and clean. Communication was great. Easy entry. Coffee, tea, water and snacks were awesome, thanks Kisha! Everything you need is there. Suite B had renters but we never heard any sound at all from them. The only issue for us was that the 2 Plug ins were way too strong for the small area, even after we unplugged them."
United States
Mary h.
The price is CA $146
CA $177 total
includes taxes & fees
Dec 1 - Dec 2
Peaceful Retreat at Crawford Farms – Quiet and Comfortable for Work or Relaxing.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top reviews in Pamplico

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
The Inn at the Crossroads

The Inn at the Crossroads

The Inn at the Crossroads
Lake City

10/10 Excellent

Super bel hôtel ! Une belle découverte.
Canada
Gael
Reviewed June 27, 2026
The Inn at the Crossroads

Frequently Asked Questions

Searching for B&Bs in Pamplico?

Whether you're on a romantic trip and want to stay somewhere quiet and intimate, or you're traveling solo and looking to chat with locals, a B&B might be the right choice for your trip.

How do you know if a B&B is the best choice for you?

Every B&B has its own unique feel. Whether it's a picturesque garden or a beautiful dining room, the quaint details are what make bed and breakfasts the perfect escape.

What are the best B&Bs in Pamplico?

Below is a B&B in the area: Rosewood Manor House B&B: 5 rooms. 16.5 mi (26.5 km) from the heart of Pamplico. Enjoy the free full breakfast and deli.

What's the best time of year to stay at a B&B in Pamplico?

When you're planning your getaway to Pamplico, year-round temperatures and rainfall may be important factors to consider. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Pamplico is 53 inches.

How can I get to and around Pamplico?

Mapping out your trip in and around Pamplico is easy with these transportation options. Fly into Florence, SC (FLO-Florence Regional), which is located 16.4 mi (26.4 km) from the heart of the city. If you'd like to explore around the area, you may want a rental car for your journey.

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