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Live the high life at these luxury properties


Check prices on hotels in Florence

Tonight 25 Apr. - 26 Apr.
This weekend 26 Apr. - 28 Apr.
Next weekend 3 May - 5 May

Featured Florence Luxury Hotels

See all 121 properties in Florence

Estimated price for 1 night/2 adults

The Mantissa Executive Suites and Spa
The Mantissa Executive Suites and Spa
3.0 out of 5.0 130 East Carolina Ave, Hartsville, SC
Free Cancellation
4.8/5 (65 reviews)
C$187/ night for 2 guests

Very very clean. Very nice rooms. Would stay there anytime

Reviewed on 20 Feb. 2019
Days Inn by Wyndham Dillon
Days Inn by Wyndham Dillon
2.0 out of 5.0 823 Radford Blvd, Dillon, SC
Free Cancellation
2.7/5 (279 reviews)
C$115/ night for 2 guests

Everyone was super nice and helpful. We did have to switch rooms once and then our second room fridge flooded the floor and had to get it cleaned up

Reviewed on 22 Apr. 2019
Hotel Florence, an Ascend Hotel Collection Member
Hotel Florence, an Ascend Hotel Collection Member
3.0 out of 5.0 136 W Evans St, Florence, SC
Free Cancellation
4.6/5 (199 reviews)
C$133/ night for 2 guests

Location was great, very cozy and well appointed. Will stay again.

Reviewed on 10 Apr. 2019
Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2.0 out of 5.0 2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Free Cancellation
3.5/5 (990 reviews)
C$87/ night for 2 guests

THE ROOM UPDATES AND AMENITIES WERE EXCELLENT , THE TOWELS NEED TO BE UPDATED.

Reviewed on 23 Apr. 2019
Baymont Inn & Suites Florence by Wyndham
Baymont Inn & Suites Florence by Wyndham
2.0 out of 5.0 1826 W Lucas Street, Florence, SC
Free Cancellation
3.4/5 (2,004 reviews)
C$73/ night for 2 guests

The ability to check in late was great but the line was strangely long for almost midnight and there was only one person working. After checking in everything was quick and efficient.

Reviewed on 21 Apr. 2019
Rodeway Inn & Suites
Rodeway Inn & Suites
3.0 out of 5.0 1819 West Lucas Street, Florence, SC
Free Cancellation
2.3/5 (12 reviews)
C$70/ night for 2 guests

Our stop was a quick one night on the way to see family. The staff at check was fantastic. She asked if we had eaten supper yet and made recommendations. The hotel is old but the room was very clean and spacious and the bed new. We were inside the courtyard area so it was quiet. Bar staff were friendly ...

Reviewed on 3 Jan. 2019
Red Roof Inn Florence - Civic Center
Red Roof Inn Florence - Civic Center
2.0 out of 5.0 2690 David H McLeod Boulevard, Florence, SC
Free Cancellation
3.5/5 (1,267 reviews)
C$68/ night for 2 guests

It was quiet,clean,and room smelled good.All furniture updated,and clean bed sheets...

Reviewed on 19 Apr. 2019
Days Inn by Wyndham Florence Near Civic Center
Days Inn by Wyndham Florence Near Civic Center
2.5 out of 5.0 140 Dunbarton Dr, Florence, SC
Free Cancellation
3.2/5 (1,092 reviews)
C$110/ night for 2 guests

Nice bed. Only con was paint was peeling in some parts of the room. Price was good. I would stay here again.

Reviewed on 10 Jan. 2019
Quality Inn & Suites
Quality Inn & Suites
2.5 out of 5.0 817 Radford Blvd, Dillon, SC
Free Cancellation
3.8/5 (217 reviews)
C$128/ night for 2 guests

Comp breakfast. No gym amenities

Reviewed on 15 Apr. 2019
Map

Recently booked Florence hotels

Red Roof Inn Florence - Civic Center
2.0 out of 5.0
Last booking: 55 minutes ago
Quality Inn And Suites Civic
2.5 out of 5.0
Last booking: 1 hour ago
Days Inn by Wyndham Florence/I-95 North
2.0 out of 5.0
Last booking: 3 hours ago
Baymont Inn & Suites Florence by Wyndham
2.0 out of 5.0
Last booking: 4 hours ago

Want to find the perfect hotel for your luxury holiday in Florence? Use Expedia to arrange your flight to Florence, SC (FLO-Florence Regional) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a vacation, so we make it easy to find what you want to make your stay special. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Florence offers. During your visit, you might want to enjoy the shopping which Florence is known for.


When to Visit Florence


Here's what you can expect from the weather when you are staying in Florence:


  • Hottest months: July, August, June, and September, with an average temperature of 90°F
  • Coldest months: January, December, February, and November, with an average temperature of 36°F
  • Driest months: April, November, February, and December, with an average rainfall of 2.81 inches
  • Rainiest months: July, August, June, and September, with an average rainfall of 4.69 inches

Exploring Florence


Experience all that Florence has to offer when you visit Florence Museum, Magnolia Mall, and Florence Civic Center. If you have spare time during your trip, you might want to make a stop at Florence Motor Speedway and Coker College.


Some other things that make Florence unique are its:
  • Restaurants
  • Shopping
  • Cafés
  • Museums
  • Excursions
  • Gardens
  • Entertainment

Getting Around Florence


Take advantage of local transportation options that make it easy to see Florence. To see more of the surrounding area, hop aboard a train at Florence Station or Dillon Station.