Default HTG hotel image

Find hotels in Pamplico, SC from CA $68

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 10 - Aug 11
Tomorrow
Aug 11 - Aug 12
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

Filter by

Star rating

Guest rating

Our top choices for Pamplico hotels

1. The Inn at the Crossroads

The Inn at the Crossroads
Lake City
United States
Bryant Keith
CA $133
CA $149 total
includes taxes & fees
Aug 24 - Aug 25
The Inn at the Crossroads

2. Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
Lake City
United States
patrick
CA $142
CA $159 total
includes taxes & fees
Sep 1 - Sep 2
Quality Inn & Suites Lake City

3. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
United States
Mhd
CA $159
CA $178 total
includes taxes & fees
Aug 17 - Aug 18
Hyatt Place Florence Downtown

4. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Florence
United States
Tim
CA $170
CA $204 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

5. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
United States
Kimberly
CA $100
CA $111 total
includes taxes & fees
Sep 7 - Sep 8
Park Inn by Radisson Florence, SC

6. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
United States
Monica
CA $148
CA $166 total
includes taxes & fees
Aug 24 - Aug 25
Comfort Inn & Suites Florence Center Area

7. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
United States
Miriam
CA $89
CA $100 total
includes taxes & fees
Sep 8 - Sep 9
Howard Johnson by Wyndham Florence

8. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
United States
Tameka
CA $159
CA $178 total
includes taxes & fees
Aug 11 - Aug 12
TownePlace Suites by Marriott Florence

9. Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
Lake City
United States
Emma
CA $139
CA $155 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn by Wyndham Lake City

10. Best Western Inn

Best Western Inn
Florence
United States
Michael
CA $124
CA $139 total
includes taxes & fees
Aug 11 - Aug 12
Best Western Inn

11. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
Florence
United States
John
CA $193
CA $216 total
includes taxes & fees
Aug 23 - Aug 24
Hotel Florence, Tapestry Collection by Hilton

12. Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
United States
Jennifer
CA $125
CA $145 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Suites Florence I-95

13. Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
Marion
United States
April
CA $127
CA $139 total
includes taxes & fees
Sep 2 - Sep 3
Quality Inn Mullins - Marion

14. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
United States
Andrew
CA $159
CA $178 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

15. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
United States
Mariangela
CA $153
CA $172 total
includes taxes & fees
Aug 16 - Aug 17
Hampton Inn & Suites Florence-North-I-95

16. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
United States
Brian
CA $171
CA $191 total
includes taxes & fees
Aug 16 - Aug 17
Fairfield Inn & Suites by Marriott Florence I-20

17. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
United States
Samantha
CA $125
CA $145 total
includes taxes & fees
Aug 17 - Aug 18
Spark by Hilton Florence North I-95, SC

18. Florence Inn and Suites

Florence Inn and Suites
Florence
United States
Payton
CA $68
CA $76 total
includes taxes & fees
Aug 30 - Aug 31
Florence Inn and Suites

19. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
United States
Heather
CA $133
CA $158 total
includes taxes & fees
Aug 16 - Aug 17
SpringHill Suites by Marriott Florence

20. Super 8 by Wyndham Florence SC I-95 North / Hwy 76

Super 8 by Wyndham Florence SC I-95 North / Hwy 76
Florence
United States
Vincent
CA $72
CA $80 total
includes taxes & fees
Aug 11 - Aug 12
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Pamplico Hotel Reviews

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent
"It's a nice hotel. Good restaurants nearby and staff are very friendly."
Mary 1-night trip
Posted 1 hour ago
Hyatt Place Florence Downtown
Best Western Inn

Best Western Inn

10/10 Excellent
"Our stay was excellent. The staff was so nice and respectful. They were warm and welcoming. They truly care about what they do and other people. The room was clean and it smelled great. The lobby was clean as well. Not a huge selection for breakfast but was still delicious and there was enough to choose from."
Jessica 2-night trip
Posted 5 hours ago
Best Western Inn
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"Excellent property. Breakfast was terrific and space was very comfortable. Room was really good!"
Susan 1-night trip
Posted 8 hours ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

8/10 Good
"Property was clean and the staff was very helpful and super nice!"
Demetrius 1-night trip
Posted 23 hours ago
SpringHill Suites by Marriott Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

10/10 Excellent
"Convenient location, staff was friendly and helpful finding local restaurants and easy check-in and checkout."
Richard 1-night trip
Posted 23 hours ago
Park Inn by Radisson Florence, SC
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

10/10 Excellent
"Great location, great amenities and great staff. Clean, quiet and super comfortable"
Caleb 1-night trip
Posted 23 hours ago
Staybridge Suites Florence - Civic Center by IHG
Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

8/10 Good
"The breakfast sucked."
Dreamalene 1-night trip
Posted 2 days ago
Super 8 by Wyndham Florence
Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

10/10 Excellent
"Staff nice"
Roshaunda 2-night trip
Posted 6 days ago
Days Inn by Wyndham Florence/I-95 North
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

8/10 Good
"Room was musty smelling when we first arrived but we changed the ac setting to “dry” and that helped a lot. TV was not working at first, but Maintenance arrived promptly and was able to fix it. It just needed to be rebooted. Front desk had a printed list of local restaurants which was very helpful."
Patricia 1-night trip
Posted 7 days ago
Hampton Inn & Suites Florence Center

More cheap stays in Pamplico

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC
CA $73
CA $82 total
Aug 30 - Aug 31
includes taxes & fees
Days Inn by Wyndham Florence/I-95 North
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC
CA $89
CA $100 total
Sep 8 - Sep 9
includes taxes & fees
Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC
CA $100
CA $111 total
Sep 7 - Sep 8
includes taxes & fees
Park Inn by Radisson Florence, SC
Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC
CA $121
CA $136 total
Aug 12 - Aug 13
includes taxes & fees
8.6/10 Excellent! (318 reviews)
Quality Inn & Suites Florence Civic Center
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC
CA $148
CA $166 total
Aug 24 - Aug 25
includes taxes & fees
Comfort Inn & Suites Florence Center Area
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC
CA $153
CA $172 total
Aug 23 - Aug 24
includes taxes & fees
9/10 Wonderful! (939 reviews)
Hampton Inn & Suites Florence Center

Hotels in Pamplico with star rating

Frequently asked questions

What is the best area to stay in Pamplico?
The best area to stay in Pamplico is within the town centre itself, particularly around Main Street.This area is the heart of Pamplico, offering the most convenience for visitors. Main Street is where you'll find the majority of local businesses, including small shops and eateries, and it's easily navigable on foot. The town's historic charm is evident in the architecture of the older buildings lining the street.For solo travellers or couples, staying within the town centre provides easy access to local life and amenities. You'll be able to stroll to local cafes for breakfast or explore the few boutique shops without needing a car.
When is the best time to go to Pamplico?
The best time to visit Pamplico, South Carolina, is during the spring (April to May) and autumn (September to October) months.These seasons offer pleasant weather conditions, with comfortable temperatures and lower humidity compared to the summer. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat.For those interested in local agricultural events and the natural beauty of the Pee Dee Region, these periods often coincide with local festivals and the blooming or changing colours of the landscape.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Pamplico.
How much is the nightly rate at a Pamplico hotel?
Prices for hotels in Pamplico often vary, but you can find a great deal from CA $68 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia