Title: Car Rental Florence Regional Airport (FLO) - Expedia.ca [Florence Travel Guide](https://expedia.ca/Florence.dx1221)[Florence Regional Hotels](https://expedia.ca/Florence-Regional-Airport-Hotels.0-a6027805-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Florence Vacation Packages](https://expedia.ca/Florence.d1221.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rental Florence Regional Airport (FLO) ## Search and Compare from car companies in Florence Regional ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in Florence Regional \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Florence, South Carolina, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Florence,%20SC,%20United%20States%20of%20America%20(FLO-Florence%20Regional)&dpln=6027805&date1=16/10/2025&date2=18/10/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Florence, South Carolina, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Florence,%20SC,%20United%20States%20of%20America%20(FLO-Florence%20Regional)&dpln=6027805&date1=16/10/2025&date2=18/10/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Florence, South Carolina, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Florence,%20SC,%20United%20States%20of%20America%20(FLO-Florence%20Regional)&dpln=6027805&date1=16/10/2025&date2=18/10/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Florence, South Carolina, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Florence,%20SC,%20United%20States%20of%20America%20(FLO-Florence%20Regional)&dpln=6027805&date1=16/10/2025&date2=18/10/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Florence Regional [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Florence,%20SC,%20United%20States%20of%20America%20(FLO-Florence%20Regional)&dpln=6027805&date1=16/10/2025&date2=18/10/2025&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day from Florence, SC (FLO-Florence Regional)? > Based on prices found within the past seven days, the lowest rate for a cheap rental from Florence, SC (FLO-Florence Regional) was per day. ### Can I rent a car from Florence Regional Airport (FLO)? > There's an impressive range of rental providers at Florence, SC (FLO-Florence Regional), so finding your dream ride will be a cinch. Compare the offers from Budget, Avis, Alamo, Hertz and National Car Rental. ### What happens if I need to cancel my Florence, SC (FLO-Florence Regional) car reservation? > Our [Customer Service Portal](https://www.expedia.ca/service/?langid=1033) has all the details about cancellations. But generally, refunds are available if a prepaid reservation is canceled at least six hours before the pickup time. There are some exceptions, so make sure you understand your car rental agreement. ### How do I find the best car rental deals at Florence, SC (FLO-Florence Regional) with Expedia? > Getting an awesome deal on your Florence, SC (FLO-Florence Regional) rental car is a piece of cake with Expedia. Choose your preferred ride, add some details and compare prices across big-name suppliers. Why not add flights and hotels to your booking? You'll unlock even bigger savings when you create a vacation package. ### How old do you have to be to rent a car from Florence, SC (FLO-Florence Regional)? > If you're at least 21, you can rent a car in Florence County. Are you a younger driver? Most outlets will impose a surcharge. Age limits on premium and full-size vehicles, such as SUVs and vans, might also apply. Check with your selected outlet to avoid any troubles at pickup. ### What do you need to rent a car from Florence, SC (FLO-Florence Regional)? > A driver's license and credit card are the two main prerequisites when booking a rental car from Florence, SC (FLO-Florence Regional). If you're planning on opting out of the rental company's insurance plan, you might also need your own proof of coverage. These requirements can differ between outlets, so it's a good idea to check the details before pickup. ### What is the cheapest car rental at Florence, SC (FLO-Florence Regional)? > Your budget will be happy to hear that was the cheapest daily price for a rental car from Florence, SC (FLO-Florence Regional) within the past seven days. With rates like this, you'll be taking to the road with money to spare. ### Can I rent a car for a month or longer from Florence, SC (FLO-Florence Regional)? > From compact vehicles to roomy SUVs, we offer an excellent range of extended rentals. Simply enter your dates into our [long-term car rental deals](https://www.expedia.ca/lp/b/car-hire/long-term) page, choose your preferred car class and style and we'll help you get the best price possible on your Florence, SC (FLO-Florence Regional) ride. ### Where can I find a Florence, SC (FLO-Florence Regional) car rental if I am younger than 25? > Each car rental supplier can set its own policies and decide who they will or will not rent to. So, if you're under 25, you'll need to do your homework. While some suppliers may set their minimum age at 21, others will have higher age limits. You'll find this information in the terms and conditions of the Florence, SC (FLO-Florence Regional) provider you're considering. ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | --- | --- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Lodging - Flights - Cars - Vacation Rental - Other - [5 Star Hotels in Florence](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Coward Hotels](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [B&B in Darlington](https://www.expedia.ca/Darlington-Bed-And-Breakfast.d7558-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Darlington](https://www.expedia.ca/Darlington-Guest-Houses.d7558-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Beach-Hotel.0-0-d7558-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Boutique-Hotel.0-0-d7558-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Cheap-Hotels.0-0-d7558-tCheapHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Family-Hotel.0-0-d7558-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Historic-Hotel.0-0-d7558-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Luxury-Hotel.0-0-d7558-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Pet-Friendly-Hotel.0-0-d7558-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Spa-Hotel.0-0-d7558-tSpaHotel.Travel-Guide-Filter-Hotels) - [Darlington Hotels](https://www.expedia.ca/Darlington-Hotels.d7558.Travel-Guide-Hotels) - [Motels in Darlington](https://www.expedia.ca/Darlington-Motels.d7558-aaMotels.Travel-Guide-Accommodation) - [Hotels near Darlington Raceway](https://www.expedia.ca/Darlington-Raceway-Hotels.0-l6144924-0.Travel-Guide-Filter-Hotels) - [Darlington County Hotels](https://www.expedia.ca/Destinations-In-Darlington-County.d553248635976432334.Hotel-Destinations) - [Cheap Hotels in Florence County](https://www.expedia.ca/Destinations-In-Florence-County-Cheap-Hotels.0-0-d553248635976432658-tCheapHotels.Hotel-Filter-Destinations) - [Luxury Hotels in Florence County](https://www.expedia.ca/Destinations-In-Florence-County-Luxury-Hotel.0-0-d553248635976432658-tLuxuryHotel.Hotel-Filter-Destinations) - [Florence County Hotels](https://www.expedia.ca/Destinations-In-Florence-County.d553248635976432658.Hotel-Destinations) - [Farmstay in Florence](https://www.expedia.ca/Florence-Agritourism.d1221-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Florence](https://www.expedia.ca/Florence-Apart-Hotels.d1221-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Florence](https://www.expedia.ca/Florence-Apartments.d1221-aaApartments.Travel-Guide-Accommodation) - [B&B in Florence](https://www.expedia.ca/Florence-Bed-And-Breakfast.d1221-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Florence Civic Center](https://www.expedia.ca/Florence-Civic-Center-Hotels.0-l6165605-0.Travel-Guide-Filter-Hotels) - [B&B in Florence County](https://www.expedia.ca/Florence-County-Bed-And-Breakfast.d553248635976432658-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Florence County](https://www.expedia.ca/Florence-County-Guest-Houses.d553248635976432658-aaGuestHouses.Travel-Guide-Accommodation) - [Guest Houses in Florence](https://www.expedia.ca/Florence-Guest-Houses.d1221-aaGuestHouses.Travel-Guide-Accommodation) - [Boutique Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Boutique-Hotel.0-0-d1221-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Business-Hotel.0-0-d1221-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Cheap-Hotels.0-0-d1221-tCheapHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Golf-Hotel.0-0-d1221-tGolfHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Historic-Hotel.0-0-d1221-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Florence](https://www.expedia.ca/Florence-Hotels-Hotel-With-Pool.0-0-d1221-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Balconies.0-0-d1221-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Free-Breakfast.0-0-d1221-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Hot-Tubs.0-0-d1221-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Indoor-Pool.0-0-d1221-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Kitchenettes.0-0-d1221-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Smoking-Rooms.0-0-d1221-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Florence](https://www.expedia.ca/Florence-Hotels-Hotels-With-Tennis-Courts.0-0-d1221-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [Lake Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Lake-Hotels.0-0-d1221-tLakeHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Luxury-Hotel.0-0-d1221-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Pet-Friendly-Hotel.0-0-d1221-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Spa Hotels in Florence](https://www.expedia.ca/Florence-Hotels-Spa-Hotel.0-0-d1221-tSpaHotel.Travel-Guide-Filter-Hotels) - [Florence Hotels](https://www.expedia.ca/Florence-Hotels.d1221.Travel-Guide-Hotels) - [Motels in Florence](https://www.expedia.ca/Florence-Motels.d1221-aaMotels.Travel-Guide-Accommodation) - [Hotels near Florence Motor Speedway](https://www.expedia.ca/Florence-Motor-Speedway-Hotels.0-l6215468-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Florence Station](https://www.expedia.ca/Florence-Station-Apart-Hotels.d6195493-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Florence Station](https://www.expedia.ca/Florence-Station-Bed-And-Breakfast.d6195493-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels near Florence Station](https://www.expedia.ca/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Francis Marion University](https://www.expedia.ca/Francis-Marion-University-Hotels.0-l6162133-0.Travel-Guide-Filter-Hotels) - [Hotels near Magnolia Mall](https://www.expedia.ca/Magnolia-Mall-Hotels.0-l6165602-0.Travel-Guide-Filter-Hotels) - [Hotels near Mcleod Regional Medical Center](https://www.expedia.ca/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Sellers](https://www.expedia.ca/Sellers-Apart-Hotels.d3000353228-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Sellers](https://www.expedia.ca/Sellers-Bed-And-Breakfast.d3000353228-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cheap Hotels in Sellers](https://www.expedia.ca/Sellers-Hotels-Cheap-Hotels.0-0-d3000353228-tCheapHotels.Travel-Guide-Filter-Hotels) - [Sellers Hotels](https://www.expedia.ca/Sellers-Hotels.d3000353228.Travel-Guide-Hotels) - [Motels in Sellers](https://www.expedia.ca/Sellers-Motels.d3000353228-aaMotels.Travel-Guide-Accommodation) - [Rv Parks in Sellers](https://www.expedia.ca/Sellers-RV-Parks.d3000353228-aaRVParks.Travel-Guide-Accommodation) - [Hotels near The Traces Golf Club](https://www.expedia.ca/The-Traces-Golf-Club-Hotels.0-l6162131-0.Travel-Guide-Filter-Hotels) - [Timmonsville Hotels](https://www.expedia.ca/Timmonsville-Hotels.d180880.Travel-Guide-Hotels) - [Flights to Darlington](https://www.expedia.ca/Cheap-Flights-To-Darlington.d7558.Travel-Guide-Flights) - [Flights to Florence](https://www.expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights) - [Flights to Florence County](https://www.expedia.ca/Destinations-In-Florence-County.d553248635976432658.Flight-Destinations) - [Flights from Coward](https://www.expedia.ca/lp/flights/3000353109/flights-from-coward) - [Car rental Camden](https://www.expedia.ca/Car-Rentals-In-Camden.d85740.Car-Rental-Guide) - [Car rental Conway](https://www.expedia.ca/Car-Rentals-In-Conway.d7416.Car-Rental-Guide) - [Car rental Cross](https://www.expedia.ca/Car-Rentals-In-Cross.d3000455898.Car-Rental-Guide) - [Car rental Darlington](https://www.expedia.ca/Car-Rentals-In-Darlington.d7558.Car-Rental-Guide) - [Car rental Dillon](https://www.expedia.ca/Car-Rentals-In-Dillon.d6871.Car-Rental-Guide) - [Car rental Elgin](https://www.expedia.ca/Car-Rentals-In-Elgin.d6051125.Car-Rental-Guide) - [Car rental Florence](https://www.expedia.ca/Car-Rentals-In-Florence.d1221.Car-Rental-Guide) - [Car rental Georgetown](https://www.expedia.ca/Car-Rentals-In-Georgetown.d7454.Car-Rental-Guide) - [Car rental Hartsville](https://www.expedia.ca/Car-Rentals-In-Hartsville.d7762.Car-Rental-Guide) - [Car rental Kingstree](https://www.expedia.ca/Car-Rentals-In-Kingstree.d601795.Car-Rental-Guide) - [Car rental Lake City](https://www.expedia.ca/Car-Rentals-In-Lake-City.d8506.Car-Rental-Guide) - [Car rental Lancaster](https://www.expedia.ca/Car-Rentals-In-Lancaster.d8527.Car-Rental-Guide) - [Car rental Latta](https://www.expedia.ca/Car-Rentals-In-Latta.d6047058.Car-Rental-Guide) - [Car rental Little River](https://www.expedia.ca/Car-Rentals-In-Little-River.d8424.Car-Rental-Guide) - [Car rentals near Man O' War](https://www.expedia.ca/Car-Rentals-In-Man-O-War.d553248621532657352.Car-Rental-Guide) - [Car rental Manning](https://www.expedia.ca/Car-Rentals-In-Manning.d8454.Car-Rental-Guide) - [Car rental Murrells Inlet](https://www.expedia.ca/Car-Rentals-In-Murrells-Inlet.d10085.Car-Rental-Guide) - [Car rentals near Myrtle Beach Boardwalk](https://www.expedia.ca/Car-Rentals-In-Myrtle-Beach-Boardwalk.d6161378.Car-Rental-Guide) - [Rental cars Myrtle Beach Intl. airport](https://www.expedia.ca/Car-Rentals-In-Myrtle-Beach-Intl.d5396813.Car-Rental-Guide) - [Car rentals near Myrtle Beach Sling Shot](https://www.expedia.ca/Car-Rentals-In-Myrtle-Beach-Sling-Shot.d553248621532661065.Car-Rental-Guide) - [Car rental Myrtle Beach](https://www.expedia.ca/Car-Rentals-In-Myrtle-Beach.d601685.Car-Rental-Guide) - [Car rentals near North Myrtle Beach Beaches](https://www.expedia.ca/Car-Rentals-In-North-Myrtle-Beach-Beaches.d553248635976496794.Car-Rental-Guide) - [Car rental North Myrtle Beach](https://www.expedia.ca/Car-Rentals-In-North-Myrtle-Beach.d8929.Car-Rental-Guide) - [Car rental Pawleys Island](https://www.expedia.ca/Car-Rentals-In-Pawleys-Island.d55498.Car-Rental-Guide) - [Car rental Santee](https://www.expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide) - [Car rentals near South of the Border](https://www.expedia.ca/Car-Rentals-In-South-Of-The-Border.d3000456123.Car-Rental-Guide) - [Car rentals near Splashes Oceanfront Water Park](https://www.expedia.ca/Car-Rentals-In-Splashes-Oceanfront-Water-Park.d553248621532655062.Car-Rental-Guide) - [Car rental St. Pauls](https://www.expedia.ca/Car-Rentals-In-St-Pauls.d12073.Car-Rental-Guide) - [Car rental St. Stephen](https://www.expedia.ca/Car-Rentals-In-St-Stephen.d6135438.Car-Rental-Guide) - [Car rental Sumter](https://www.expedia.ca/Car-Rentals-In-Sumter.d6058099.Car-Rental-Guide) - [Enterprise Rental Cars in Darlington](https://www.expedia.ca/Enterprise-Car-Rentals-In-Darlington.d7558-c15.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Florence](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Florence.d1221-c45.Car-Rental-Guide-Suppliers) - [Darlington Vacation Rentals](https://www.expedia.ca/Darlington-Vacation-Rentals.d7558.Travel-Guide-VacationRentals) - [Things to do in Pamplico](https://www.expedia.ca/Things-To-Do-In-Pamplico.d3000353197.Travel-Guide-Activities)