Find hotels in Lake City, SC from CA $78

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Compare 85 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Residence Inn Marriott Florence

3.0 star property
8.8 out of 10, Excellent, (415)
"The staff and the breakfast was amazing!!"
The price is CA $154
CA $173 total
includes taxes & fees
Sep 2 - Sep 3
Residence Inn Marriott Florence

Aloft Florence

3.0 star property
8.4 out of 10, Very good, (179)
"Great hotel"
The price is CA $164
CA $183 total
includes taxes & fees
Sep 1 - Sep 2
Aloft Florence

TownePlace Suites by Marriott Florence

3.0 star property
9.0 out of 10, Wonderful, (632)
"We really enjoyed our stay!"
The price is CA $149
CA $167 total
includes taxes & fees
Aug 24 - Aug 25
TownePlace Suites by Marriott Florence

The Inn at the Crossroads

2.0 star property
9.4 out of 10, Exceptional, (759)
"The Inn at the Crossroads is stunning! We look forward to staying here again!"
The price is CA $179
CA $201 total
includes taxes & fees
Aug 26 - Aug 27
The Inn at the Crossroads

Quality Inn & Suites

2.5 star property
7.2 out of 10, Good, (157)
"I didn't like the fact that i couldn't get in the building for breakfast. No one was avaliable as well as checking in or out. The main door was lock"
The price is CA $149
CA $167 total
includes taxes & fees
Sep 17 - Sep 18
Quality Inn & Suites

Days Inn by Wyndham Lake City

2.0 star property
6.4 out of 10, (239)
"Overall good stay for 1 night. "
The price is CA $147
CA $165 total
includes taxes & fees
Aug 24 - Aug 25
Days Inn by Wyndham Lake City

Bella's Boutique Hotel

2.0 star property
6.0 out of 10, (12)
"The building is definitely out dated but it was very cute and cozy"
The price is CA $90
CA $137 total
includes taxes & fees
Aug 22 - Aug 23
Bella's Boutique Hotel

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1051)
"Good service, comfy bed and pillows!"
The price is CA $146
CA $164 total
includes taxes & fees
Sep 21 - Sep 22
Comfort Inn & Suites

Hampton Inn & Suites Florence Center

2.5 star property
9.0 out of 10, Wonderful, (765)
"Good place for a stop over "
The price is CA $164
CA $183 total
includes taxes & fees
Sep 7 - Sep 8
Hampton Inn & Suites Florence Center

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (889)
"Enjoyed the stay "
The price is CA $187
CA $210 total
includes taxes & fees
Aug 24 - Aug 25
Staybridge Suites Florence - Civic Center by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Clean, quiet , breakfast excellent "
The price is CA $164
CA $183 total
includes taxes & fees
Sep 14 - Sep 15
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
9.0 out of 10, Wonderful, (498)
"Great front desk staff"
The price is CA $158
CA $177 total
includes taxes & fees
Sep 21 - Sep 22
Fairfield Inn & Suites by Marriott Florence I-20

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1232)
"Great pool, breakfast and rooms. "
The price is CA $125
CA $140 total
includes taxes & fees
Sep 1 - Sep 2
Quality Inn & Suites Florence Civic Center

Home2 Suites by Hilton Florence, SC

3.0 star property
8.2 out of 10, Very good, (1002)
"They also had breakfast which is very nice and a gym and laundry room all good "
The price is CA $152
CA $170 total
includes taxes & fees
Sep 2 - Sep 3
Home2 Suites by Hilton Florence, SC

Affordable Suites Florence

2.5 star property
9.4 out of 10, Exceptional, (104)
"Parking was good and quiet spot"
The price is CA $90
CA $101 total
includes taxes & fees
Aug 27 - Aug 28
Affordable Suites Florence

Courtyard by Marriott Florence

3.0 star property
7.8 out of 10, Good, (662)
"Great place to stay. Clean and comfortable. Friendly staff and will definitely stay there again."
The price is CA $140
CA $157 total
includes taxes & fees
Sep 4 - Sep 5
Courtyard by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property
8.6 out of 10, Excellent, (932)
"Great place to stay. "
The price is CA $157
CA $176 total
includes taxes & fees
Sep 4 - Sep 5
SpringHill Suites by Marriott Florence

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1002)
"Good quality hotel with affordable pricing."
The price is CA $92
CA $103 total
includes taxes & fees
Aug 24 - Aug 25
Days Inn by Wyndham Florence Near Civic Center

Quality Inn Kingstree

2.5 star property
6.0 out of 10, (162)
"Is old but for one night is ok."
The price is CA $104
CA $115 total
includes taxes & fees
Sep 21 - Sep 22
Quality Inn Kingstree

Homewood Suites by Hilton Florence

3.0 star property
8.4 out of 10, Very good, (639)
"The staff were amazing and helpful. the hotel, very modern and really clean "
The price is CA $158
CA $183 total
includes taxes & fees
Sep 6 - Sep 7
Homewood Suites by Hilton Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Lake City

Stroll through Moore Farms Botanical Garden's lush landscapes, where seasonal blooms and tranquil paths await. Dive into local history at the Bean Market, a restored 1930s tobacco warehouse now hosting community events and showcasing regional culture.

Stay near popular Lake City attractions

Frequently asked questions

What's the best place for a stay in Lake City?

The Inn at the Crossroads is a favorite with Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Quality Inn & Suites and Days Inn by Wyndham Lake City as top choices for your stay. See all available top hotels, or vacation rentals in Lake City.

What's the top vacation rental in Lake City?

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This vacation home rental outside of Lake City is equipped with a fireplace, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in Lake City.

If I need to cancel my hotel reservation in Lake City, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Lake City.

Where can I learn more about changing or cancelling my trip to Lake City?

For additional details about rescheduling or cancelling your trip to Lake City, go to https://www.expedia.com/service/.

What is the top LGBTQ-friendly accommodation in Lake City?

The Inn at the Crossroads is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Lake City.

What's the best pet-friendly hotel in Lake City?

Days Inn by Wyndham Lake City is a top pet-friendly option for your stay. Olives Bed and Breakfast is a beautiful 1919 home that takes you back in time. is another good option for a stay with your pet. See more pet-friendly hotel accommodations in Lake City.

Where is the best hotel to stay with easy access to Lions Park?

The Inn at the Crossroads is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.6 mi (0.9 km) from Lions Park. Other good options close by include Quality Inn & Suites and Days Inn by Wyndham Lake City.

What about the best place to stay near The Country Club at Lake City?

One of the top choices for your stay is The Inn at the Crossroads, located 1.7 mi (2.8 km) from The Country Club at Lake City, and this hotel offers free breakfast and a restaurant. Days Inn by Wyndham Lake City and Quality Inn & Suites are other good choices within a few miles.

What are some accommodations with pools in Lake City?

Days Inn by Wyndham Lake City: Provides daily, a seasonal outdoor pool, and free self parking. Quality Inn & Suites Florence Civic Center and Comfort Inn & Suites are a couple of other choices with an onsite pool. View all hotels with pools in Lake City.

What's the best hotel for staying near Florence Regional Airport (FLO)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.

What is staying in Lake City like?

Visitors to Lake City are sure to enjoy the lakeside setting and restaurants. Tourists can also enjoy the city's shopping and parks. In Lake City, there are 4 hotels and other accommodations to choose from. Find out more about Lake City.

What is there to see in Lake City?

Natural beauty is on display at Lions Park, Moore Farms Botanical Garden, and Ronald E. McNair Life History Center. A couple of additional sights to add to your agenda are The Bean Market and Lynches Lake Historical Society. Check out what more to see and do in Expedia's Lake City guide.

What's the seasonal weather like in Lake City?

The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches.