Title: Book the Best BUSINESS Hotels in Manning in 2026 | Expedia.ca [Hotels in Manning](https://expedia.ca/Manning-Hotels.d8454.Travel-Guide-Hotels)[Vacation Rentals in Manning](https://expedia.ca/Manning-Vacation-Rentals.d8454.Travel-Guide-VacationRentals)[Flights to Manning](https://expedia.ca/Cheap-Flights-To-Manning.d8454.Travel-Guide-Flights)[Manning Car Rentals](https://expedia.ca/Car-Rentals-In-Manning.d8454.Car-Rental-Guide)[Manning Vacation Packages](https://expedia.ca/Manning.d8454.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Manning, SC from CA $100 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Manning Business Hotels Tonight [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=8454&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=8454&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=8454&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=8454&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Manning business-friendly hotels ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/ab9e6646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/f127cd7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning [](https://www.expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) Manning 8.4/10 Very good (1000) "Clean, great staff, and comfortable beds. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Micah CA $160 CA $177 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/0ca73b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e307c591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/b76457c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) Manning 8.6/10 Excellent (1002) "Easy check in and out. Friendly staff, quiet and cozy. Breakfast is average but plenty to choose from. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $123 CA $136 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1413) "Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramil CA $110 CA $122 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/8a3aa504.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) Santee 8.2/10 Very good (972) "Was able to walk to convenience store and other dinning alternatives. Safe secure building" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan CA $143 CA $159 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/24e62285.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/4ad28eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/d1fd3c46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/b50f6cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1912 Bed and Breakfast [](https://www.expedia.ca/Sumter-Hotels-1912-Bed-And-Breakfast.h26733717.Hotel-Information) Sumter 10/10 Exceptional (283) "This is a beautiful property. The host was very kind and personable. The breakfast was quite yummy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $158 CA $179 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Sumter-Hotels-1912-Bed-And-Breakfast.h26733717.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/23000000/22520000/22514800/22514748/dfc7158d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22520000/22514800/22514748/0812f37c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/23000000/22520000/22514800/22514748/e726b4a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/23000000/22520000/22514800/22514748/d629f911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Sumter / Downtown [](https://www.expedia.ca/Sumter-Hotels-Hyatt-Place-Sumter-Downtown.h22514748.Hotel-Information) Sumter 9.2/10 Wonderful (879) "Clean room and staff was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ishara CA $157 CA $176 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Sumter-Hotels-Hyatt-Place-Sumter-Downtown.h22514748.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050239/67f6e033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050239/e218961c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050239/bed37711.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050300/1050239/7ea76a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Sumter by IHG [](https://www.expedia.ca/Sumter-Hotels-Holiday-Inn-Express-Sumter.h1050239.Hotel-Information) Sumter 8.8/10 Excellent (695) "Clean room, nice staff good area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Latesha CA $135 CA $151 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Sumter-Hotels-Holiday-Inn-Express-Sumter.h1050239.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) Santee 8.8/10 Excellent (1000) "Nice rooms and very good breakfast items." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen CA $163 CA $181 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/c73a2ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/580e2ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/b79560d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/330000/327200/327193/da1ecd72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Kingstree North [](https://www.expedia.ca/Kingstree-Hotels-Quality-Inn-Kingstree.h327193.Hotel-Information) Kingstree 6.0/10 (171) "There were no light bulbs in the room lamps, and we started seeing roaches." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $90 CA $100 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Kingstree-Hotels-Quality-Inn-Kingstree.h327193.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8320000/8313500/8313401/d8d13945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8320000/8313500/8313401/081e2ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8320000/8313500/8313401/e9726464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8320000/8313500/8313401/d764718b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites Sumter [](https://www.expedia.ca/Sumter-Hotels-SpringHill-Suites-Sumter.h8313401.Hotel-Information) Sumter 9.4/10 Exceptional (451) "Room is perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandy CA $154 CA $173 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Sumter-Hotels-SpringHill-Suites-Sumter.h8313401.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=8454&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Manning Hotel Reviews ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 10/10 Excellent "Had to be moved different room" [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 10/10 Excellent "the breakfast was fresh. handicap parking close to entry" [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Hampton Inn Manning](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f_y.jpg) ### Hampton Inn Manning 10/10 Excellent "Nice and clean " [](https://expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![Comfort Inn & Suites Santee](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 10/10 Excellent "We like this location and have stayed here several times. We travel with our service dogs and this location has a nice outdoor area that is well lit at night for potty breaks. \*\*\*PLEASE NOTE…this hotel is NOT pet friendly. We will often seek out pet friendly facilities as a first option when we travel and this location comes up in the search. However upon arrival there’s a sign on the door that reads service animals only. I only mention it as a heads up. Our first stay we had prepaid for our room and if our dogs were not service animals we would have been in a bad situation as it was late when we arrived and would have had no place to go. Otherwise this is a great location and place to stay for us on our travels up and down I-95!" [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Baymont by Wyndham Manning](https://images.trvl-media.com/lodging/1000000/120000/119200/119159/2643428b_y.jpg) ### Baymont by Wyndham Manning 10/10 Excellent "My only complaint was that the bed was a little high for me and the base was surrounded by metal sheets that I kept hitting with my heel every time a got down. It was a good thing I was alone. Otherwise, that loud clang would have disturbed my companion." [](https://expedia.ca/Sumter-Hotels-Baymont-By-Wyndham-Manning.h119159.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Manning cost? ### What are the best business-friendly hotels in Manning? ### How many business-friendly hotels are there in Manning? ### Why book your business-friendly hotel in Manning with Expedia? ### How can I find cheap business-friendly hotels in Manning? ### What is there to do in Manning near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [1 Star Hotels in Sumter ](https://www.expedia.ca/1Star-Sumter-Hotels.s10-0-d6058099.Travel-Guide-Filter-Hotels) - [Apartments in Alcolu ](https://www.expedia.ca/Alcolu-Apartments.d3000422483-aaApartments.Travel-Guide-Accommodation) - [Alcolu Hotels ](https://www.expedia.ca/Alcolu-Hotels.d3000422483.Travel-Guide-Hotels) - [Cabin Rentals in Cane Savannah ](https://www.expedia.ca/Cane-Savannah-Cabins.d553248634998891946-aaCabins.Travel-Guide-Accommodation) - 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