A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacation Rentals

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Our top choices for Ladys Island vacation rentals

Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!

Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!
3.0 star property
Edgefield
10.0 out of 10, Exceptional, (1 review)
"It was like home away frim home. "
United States
Willie
The price is CA $271
CA $719 total
includes taxes & fees
Jul 4 - Jul 5
Bluffton Getaway w/ Fenced Yard: 7 Mi to Beach!

Marriott's Harbour Club

Marriott's Harbour Club
3.5 star property
Sea Pines
9.0 out of 10, Wonderful, (63 reviews)
"Clean and spacious. Very convenient location. "
United States
CLAUDIA
The price is CA $561
CA $617 total
includes taxes & fees
Jul 8 - Jul 9
Marriott's Harbour Club

Montage Palmetto Bluff Residences

Montage Palmetto Bluff Residences
5.0 star property
Palmetto Bluff
10.0 out of 10, Exceptional, (2 reviews)
"Very family friendly. Parking was a problem Check in was not one minute early. House was beautiful and very clean. Pool was wonderful Prices were high but we knew that ahead of time"
United States
john j
The price is CA $1,865
CA $2,246 total
includes taxes & fees
Aug 1 - Aug 2
Montage Palmetto Bluff Residences

Marriott's Harbour Point and Sunset Pointe at Shelter Cove

Marriott's Harbour Point and Sunset Pointe at Shelter Cove
3.5 star property
Mid Island
9.2 out of 10, Wonderful, (154 reviews)
"Very nice place to stay "
United States
Alejandro
The price is CA $751
CA $826 total
includes taxes & fees
Aug 1 - Aug 2
Marriott's Harbour Point and Sunset Pointe at Shelter Cove

St Helena Island Condo w/ Beach Views & Porch!

St Helena Island Condo w/ Beach Views & Porch!
4.0 star property
Harbor Island
The price is CA $223
CA $627 total
includes taxes & fees
Jul 3 - Jul 4
St Helena Island Condo w/ Beach Views & Porch!

Marriott's Heritage Club

Marriott's Heritage Club
3.5 star property
Sea Pines
9.4 out of 10, Exceptional, (68 reviews)
"Another great Marriott, super clean and spacious with the comforts we needed to finish out a long trip (e.g. hot tub, laundry, kitchen). Friendly staff and convenient to the forest reserve."
United States
Landry
The price is CA $652
CA $717 total
includes taxes & fees
Jul 8 - Jul 9
Marriott's Heritage Club

Marriott's Grande Ocean

Marriott's Grande Ocean
3.5 star property
South End
9.4 out of 10, Exceptional, (174 reviews)
"Very clean room, warm pools, excellent location! "
United States
Sean
The price is CA $1,208
CA $1,329 total
includes taxes & fees
Jul 8 - Jul 9
Marriott's Grande Ocean

Swim & Relax: St Helena Island Gem w/ Deck!

Swim & Relax: St Helena Island Gem w/ Deck!
4.0 star property
Harbor Island
The price is CA $273
CA $653 total
includes taxes & fees
Jul 24 - Jul 25
Swim & Relax: St Helena Island Gem w/ Deck!

Marriott's Barony Beach Club

Marriott's Barony Beach Club
3.5 star property
Mid Island
9.4 out of 10, Exceptional, (250 reviews)
"Family orientated hotel with great pools, walk on beach access, wonderful BBQ options for self catering. Rooms are large and family orientated. Fab stay! "
Australia
Pauline
The price is CA $1,260
CA $1,386 total
includes taxes & fees
Jul 7 - Jul 8
Marriott's Barony Beach Club

Marriott's Monarch at Sea Pines

Marriott's Monarch at Sea Pines
3.0 star property
Sea Pines
9.2 out of 10, Wonderful, (132 reviews)
"Loved this property "
United States
Sharon
The price is CA $1,021
CA $1,123 total
includes taxes & fees
Jul 12 - Jul 13
Marriott's Monarch at Sea Pines

Marriott's SurfWatch

Marriott's SurfWatch
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (199 reviews)
"Great resort, great room "
United States
Crista
The price is CA $1,266
CA $1,392 total
includes taxes & fees
Jul 7 - Jul 8
Marriott's SurfWatch

Pool Access & Views at Saint Helena Island Condo!

Pool Access & Views at Saint Helena Island Condo!
4.0 star property
Harbor Island
The price is CA $207
CA $667 total
includes taxes & fees
Jul 22 - Jul 23
Pool Access & Views at Saint Helena Island Condo!

Ocean-view Island Condo w/ Pool: Pets Welcome!

Ocean-view Island Condo w/ Pool: Pets Welcome!
3.5 star property
Harbor Island
9.0 out of 10, Wonderful, (2 reviews)
"The stay was really great. The bugs around the marsh and all the dead jelly fish were not so great. No complaints about the property other than unclear instructions on where to put trash. "
United States
Ashley
The price is CA $187
CA $493 total
includes taxes & fees
Jul 20 - Jul 21
Ocean-view Island Condo w/ Pool: Pets Welcome!

Pool Time & Island Vibes! Hilton Head Getaway

Pool Time & Island Vibes! Hilton Head Getaway
3.0 star property
Mid Island
The price is CA $263
CA $671 total
includes taxes & fees
Jul 31 - Aug 1
Pool Time & Island Vibes! Hilton Head Getaway

St Helena Island Condo w/ Pool & Beach Access!

St Helena Island Condo w/ Pool & Beach Access!
4.0 star property
Harbor Island
The price is CA $223
CA $627 total
includes taxes & fees
Jul 12 - Jul 13
St Helena Island Condo w/ Pool & Beach Access!

Poolside Fun & Ocean Strolls: Harbor Island Haven!

Poolside Fun & Ocean Strolls: Harbor Island Haven!
3.0 star property
Beachwalk
The price is CA $267
CA $733 total
includes taxes & fees
Jul 21 - Jul 22
Poolside Fun & Ocean Strolls: Harbor Island Haven!

Walk to Beach: Hilton Head Condo w/ Pool Access

Walk to Beach: Hilton Head Condo w/ Pool Access
3.5 star property
Mid Island
9.6 out of 10, Exceptional, (5 reviews)
"Very clean and easy access to the beach "
United States
LUMINITA
Walk to Beach: Hilton Head Condo w/ Pool Access

Beach Access: Oceanfront Hilton Head Studio

Beach Access: Oceanfront Hilton Head Studio
3.0 star property
South End
8.0 out of 10, Very good, (2 reviews)
"After a couple of bumps resolved, our stay was very good. Location is great also. We would definitely stay here again. Thanks to the owner and his hospitality crew."
United States
Marvin
The price is CA $189
CA $600 total
includes taxes & fees
Jul 18 - Jul 19
Beach Access: Oceanfront Hilton Head Studio

Oceanfront St Helena Island Condo w/ Beach Access!

Oceanfront St Helena Island Condo w/ Beach Access!
4.0 star property
Harbor Island
10.0 out of 10, Exceptional, (1 review)
"Condo is clean and had everything we needed. Very comfortable and easy access to beach! Relaxing!"
United States
Darrell
The price is CA $423
CA $848 total
includes taxes & fees
Jul 25 - Jul 26
Oceanfront St Helena Island Condo w/ Beach Access!

Oceanfront Hilton Head Island Condo w/ Pool!

Oceanfront Hilton Head Island Condo w/ Pool!
3.0 star property
South End
9.0 out of 10, Wonderful, (4 reviews)
"Nice!! Location great, easy instructions on entry access, nice side view of the ocean from the balcony, the host Meagan was so very nice and accommodating, very close to restaurants and stores, would love to stay here again, Thanks a million!!!! ;)"
United States
Beverly
The price is CA $223
CA $532 total
includes taxes & fees
Jul 8 - Jul 9
Oceanfront Hilton Head Island Condo w/ Pool!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Ladys Island Hotel Reviews

Find out more about Ladys Island

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Ladys Island. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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