Title: Hotels by Motel 6 in Depew from CA $89 | Expedia.ca [Depew Travel Guide](https://expedia.ca/Depew.dx6338362)[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.ca/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.ca/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.ca/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Depew Motel 6 ![Individually furnished, blackout drapes, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/18300/18259/32fdc4c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18300/18259/5eeb423c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18300/18259/be5e54fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18300/18259/33c94b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Buffalo, NY - Airport - Williamsville [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Buffalo.h18259.Hotel-Information) Buffalo 6.2/10 (1,226 reviews) "Roy did a good job checking in. I was surprised the room was clean and no bugs. I stayed twice recently. The price is right. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allen J CA $75 CA $89 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Buffalo.h18259.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5920000/5914200/5914180/2906234a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5920000/5914200/5914180/9dd3b7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5920000/5914200/5914180/fce211b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5920000/5914200/5914180/4c4444c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Hamburg, NY [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Hamburg.h5914180.Hotel-Information) Hamburg 6.6/10 (1,000 reviews) "We stay at this location because it's better then the motel 6 in Buffalo " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane CA $111 CA $126 total includes taxes & fees Apr 9 - Apr 10 [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Hamburg.h5914180.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/6e825f18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/072093a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/e8171ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Television](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/7e380454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Amherst, NY - Buffalo [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) Buffalo 6.4/10 (1,001 reviews) "Clean and roomy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jackson CA $83 CA $95 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23®ionId=6338362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Motel-6.0-0-d6338362--bMotel6.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Motel-6.0-0-d6338362--bMotel6.Travel-Guide-Filter-Hotels) ## Top Depew Hotel Reviews ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Hotel has a nice set up but could really use some upgrades. Bathrooms, walls, beds, hallways. Some upgrades would be nice. " [](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Comfort Inn University](https://images.trvl-media.com/lodging/1000000/70000/66600/66581/2db1a2f1_y.jpg) ### Comfort Inn University 10/10 Excellent "Yes" [](https://expedia.ca/Buffalo-Hotels-Comfort-Inn-University.h66581.Hotel-Information) ![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f_y.jpg) ### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 2/10 Terrible "Clean rooms, friendly staff, good wifi, but the breakfast was terrible. Me and my girlfriend got food poisoning. They really need to step up their breakfast for a hotel. Overall 2.5/5 because of the breakfast. " [](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) ![Hyatt Place Buffalo/Amherst](https://images.trvl-media.com/lodging/10000000/9460000/9456500/9456445/5bccc2ed_y.jpg) ### Hyatt Place Buffalo/Amherst 10/10 Excellent "Hotel is beautiful well maintained friendly staff beautiful rooms " [](https://expedia.ca/Buffalo-Hotels-Hyatt-Place-BuffaloAmherst.h9456445.Hotel-Information) ![Tru by Hilton Williamsville Buffalo Airport](https://images.trvl-media.com/lodging/22000000/21330000/21330000/21329922/9b6ff48b_y.jpg) ### Tru by Hilton Williamsville Buffalo Airport 8/10 Good "Nice no frills hotel for a 1 night stay. " [](https://expedia.ca/Buffalo-Hotels-Tru-By-Hilton-Williamsville-Buffalo-Airport.h21329922.Hotel-Information) ![Aloft Buffalo Airport](https://images.trvl-media.com/lodging/10000000/9280000/9277900/9277828/9352f0af_y.jpg) ### Aloft Buffalo Airport 10/10 Excellent "Awesome " [](https://expedia.ca/Buffalo-Hotels-Aloft-Buffalo-Airport.h9277828.Hotel-Information) ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50_y.jpg) ### Buffalo Airport Hotel 8/10 Good "Rooms were clean" [](https://expedia.ca/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/6499bfe4_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 10/10 Excellent "clean room, breakfast was great, staff was friendly" [](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3_y.jpg) ### Sleep Inn & Suites Buffalo Airport 6/10 Okay "We were told our room would be ready in 45 minutes and when we came back they told us it still wasn't ready. After my Husband got upset they ended up switching us to a room that was ready across the hall. We don't know why it took my husband getting upset for them to not have done that in the first place." 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