Title: Book the Best BUSINESS Hotels in Central in 2025 | Expedia.ca [Hotels in Central](https://expedia.ca/Central-Hotels.d10503.Travel-Guide-Hotels)[Vacation Rentals in Central](https://expedia.ca/Central-Vacation-Rentals.d10503.Travel-Guide-VacationRentals)[Central Car Rentals](https://expedia.ca/Car-Rentals-In-Central.d10503.Car-Rental-Guide)[Central Vacation Packages](https://expedia.ca/Central.d10503.Destination-Travel-Guides) ![A beautiful and relaxing place. Perfect place to unwind.](https://images.trvl-media.com/place/553248635056396940/05df6589-b9be-4432-8fc1-03453cec9796.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Victoria S # Find Business Hotels in Central, SC from CA $89 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Business Hotels Tonight [Nov 12 - Nov 13](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 13 - Nov 14](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-11-13&endDate=2025-11-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Central Business Hotels ## Top Central Hotel Reviews ![Microtel Inn & Suites by Wyndham Anderson/Clemson](//images.trvl-media.com/lodging/3000000/2740000/2739300/2739237/f93d0c73_y.jpg) ### Microtel Inn & Suites by Wyndham Anderson/Clemson 10/10 Excellent "Clean room, attentive staff." [](https://expedia.ca/Anderson-Hotels-Microtel-Inn-Suites-By-Wyndham-AndersonClemson.h2739237.Hotel-Information) ![Baymont by Wyndham Easley/Greenville](//images.trvl-media.com/lodging/1000000/570000/569400/569381/f18cfd05_y.jpg) ### Baymont by Wyndham Easley/Greenville 10/10 Excellent "It wasn't great, but it was better than the other 2 cheaper options on town. Breakfast of eggs, sausage, make your own waffle, yogurt, bagels, etc... small TV in the room." [](https://expedia.ca/Easley-Hotels-Baymont-By-Wyndham-EasleyGreenville.h569381.Hotel-Information) ![Comfort Inn & Suites Clemson - University Area](//images.trvl-media.com/lodging/1000000/20000/19100/19019/e51fff20_y.jpg) ### Comfort Inn & Suites Clemson - University Area 10/10 Excellent "The hotel was amazing with the exception of the front desk clerk. She was rude." [](https://expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Days Inn by Wyndham Anderson](//images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Didn't Eat" [](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Inn @ Clemson](//images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 10/10 Excellent "Good" [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Restaurant connected to hotel" [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](//images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg) ### Quality Inn Seneca Clemson Area US-123 10/10 Excellent "Everything has been very good with staff, the room and the property. Would ask that on the days there is no housekeeping service that the trash and fresh towels would be addressed. " [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Hampton Inn Easley](//images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/65554714_y.jpg) ### Hampton Inn Easley 10/10 Excellent "The girl at the counter was a delight and the hotel is very nice :) " [](https://expedia.ca/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information) ![Clemson University's James F. Martin Inn](//images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/49a2146a_y.jpg) ### Clemson University's James F. Martin Inn 10/10 Excellent "Beautiful hotel, great space in rooms, close to campus yet feels like a secluded resort with the and golf course." [](https://expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ## Frequently asked questions ### How much does a business hotel in Central cost? > Take advantage of staying in a business hotel in Central, with plenty of hotels from CA $89 offering top amenities. If you're leaning toward a little luxury, prices can rise, and vary here depending on the location, season, and hotel amenities. ### Which area of Central is best to stay in for business? > The heart of Central, South Carolina, is an excellent area for business travellers seeking a blend of convenience and Southern charm. This small, yet vibrant town offers easy access to major highways, making it simple to reach nearby cities like Clemson and Anderson. With a variety of hotels equipped with modern amenities, including high-speed internet and meeting facilities, you can stay productive while enjoying a comfortable environment. > > > > For those travelling with colleagues or clients, the downtown area is particularly appealing. Its welcoming atmosphere, coupled with a selection of local restaurants and cafés, creates a great backdrop for informal meetings or post-work relaxation. You can enjoy a meal at places like The Cafe at the Grove, which serves up delicious Southern fare, or unwind at a local brewery. > > > > If you're travelling with family while on a business trip, consider accommodations that offer spacious suites or family-friendly amenities. Central is home to several parks and outdoor spaces, like the picturesque Lake Hartwell, where you can enjoy a leisurely afternoon after a busy day. This area ensures that you can balance work with quality time spent together, making it an ideal choice for professionals who value both business and family time. ### What business amenities should I look for in a hotel in Central? > When choosing a hotel for business travel in Central, it's important to find one that supports both productivity and comfort. Having reliable, high-speed Wi-Fi and a comfortable workspace in your room can make it much easier to stay focused and connected. Many hotels also offer business centres and meeting rooms, which are perfect for networking and hosting meetings. 24/7 front desk service and security provide added convenience and peace of mind, while amenities like an on-site fitness centre, dining options, and laundry services help balance work with relaxation. Additionally, easy access to public transportation or on-site parking ensures a smooth, hassle-free experience. ### How can I save on a business hotel in Central with Expedia? > [One Key™](https://www.expedia.ca/welcome-one-key) members always get our best prices. Find our best Central business hotel deals by joining Expedia's free travel rewards program. As a member, you can unlock instant savings and member perks when you're logged in. Typically, booking in advance will help you save on your business hotel booking. But, if you're making a last-minute reservation, be sure to check for last-minute deals. ### Can I cancel my business hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. 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