A calm lake with mountains in the background.

Find Adults Only Resorts & Hotels in Seneca, SC from CA $129

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Check availability on Seneca Adults Only Resorts & Hotels

Tonight
Sep 23 - Sep 24
Tomorrow
Sep 24 - Sep 25
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4
No exact matches found, but these alternatives could be just right

Recommended hotels in Seneca

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

1. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
United States
Michelle
CA $142
CA $157 total
includes taxes & fees
Oct 4 - Oct 5
Best Western Seneca-Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A food court with a beverage display, seating area, and a Clemson University sign.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

2. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
United States
Curtis
CA $149
CA $164 total
includes taxes & fees
Oct 18 - Oct 19
Tru by Hilton Seneca Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A hotel room with a bed, desk, TV, and a bathroom visible through an open door.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

3. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
United States
Julie
CA $110
CA $129 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn Seneca US-123
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern lobby with a reception desk, seating area, and a vending machine.
A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

4. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
United States
Angela
CA $181
CA $200 total
includes taxes & fees
Sep 29 - Sep 30
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A reception area with a counter, chairs, and a patterned rug.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

5. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
United States
kendra
CA $173
CA $190 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.
A spacious dining area with a long wooden table and patterned upholstered chairs.

6. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
United States
Christopher
CA $153
CA $190 total
includes taxes & fees
Sep 29 - Sep 30
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A Days Inn reception area with a view of the parking lot and trees.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.
A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
United States
Rosario
CA $120
CA $132 total
includes taxes & fees
Sep 24 - Sep 25
Days Inn by Wyndham Seneca / Clemson Area
A wooden interior with a table, chair, and a hanging lantern.
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A small black cabin with large windows, a fire pit, and a gravel ground surrounded by trees.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
United States
Nirumol
CA $142
CA $218 total
includes taxes & fees
Oct 22 - Oct 23
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.
A modern living room with a sectional sofa, a coffee table, and a television.
A hotel room with two beds, wooden flooring, and a brick wall.
A modern living room with a large dining table, white chairs, a sofa, and a television.

9. Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
United States
Joseph K.
CA $177
CA $287 total
includes taxes & fees
Oct 1 - Oct 2
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
A hallway with a wooden floor, a large mirror, and framed pictures on the walls.
A modern living room with a large dining table, white chairs, a sofa, and a television.
A modern dining area with a large table, wicker chairs, and a television in the background.
A modern living room with a sectional sofa, a coffee table, and a television.

10. Boutique hotel in historic downtown Seneca. Room #4, King bed.

Boutique hotel in historic downtown Seneca. Room #4, King bed.
Downtown
United States
Julie C.
CA $177
CA $285 total
includes taxes & fees
Sep 29 - Sep 30
Boutique hotel in historic downtown Seneca. Room #4, King bed.
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Top Seneca Hotel Reviews

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