A calm lake with mountains in the background.

Find Adults Only Resorts & Hotels in Seneca, SC from CA $129

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Check availability on Seneca Adults Only Resorts & Hotels

Tonight
Sep 22 - Sep 23
Tomorrow
Sep 23 - Sep 24
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Seneca adults-only hotels

A restaurant interior with a counter, seating area, and a TV mounted on the wall.
A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.
A multi-story motel with a central entrance, a flag, and a parking lot with several cars.
A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

1. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
United States
Julie
CA $109
CA $129 total
includes taxes & fees
Sep 24 - Sep 25
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
A multi-story hotel with a prominent entrance, parking area, and a car parked in front.
A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.
A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

2. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
United States
Michelle
CA $136
CA $150 total
includes taxes & fees
Sep 24 - Sep 25
Best Western Seneca-Clemson
An outdoor patio area with a fire pit, seating, and string lights.
A modern restaurant with a central counter, seating area, and a TV displaying news.
A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.
A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

3. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
United States
Curtis
CA $148
CA $163 total
includes taxes & fees
Oct 18 - Oct 19
Tru by Hilton Seneca Clemson
A poolside area with outdoor seating and a view of a lake and forested hills.
A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.
A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.
A modern lobby with a reception desk, seating area, and a vending machine.

4. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
United States
Angela
CA $168
CA $185 total
includes taxes & fees
Sep 27 - Sep 28
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.
A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.
A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.
A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

5. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
United States
kendra
CA $172
CA $189 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn & Suites Seneca-Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.
A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.
A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.
An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

6. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
United States
Christopher
CA $152
CA $189 total
includes taxes & fees
Sep 23 - Sep 24
Lakeside Lodge Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.
A swimming pool with lounge chairs and a fence, surrounded by trees.
A Days Inn reception area with a view of a parking lot and a grassy area.
A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
United States
Rosario
CA $122
CA $134 total
includes taxes & fees
Sep 24 - Sep 25
Days Inn by Wyndham Seneca / Clemson Area
A cabin with a cozy interior, a wooden exterior, and a view of the forest.
A wooden interior with a table, chair, and a hanging lantern.
A small black cabin with large windows, a fire pit, and a gravel ground surrounded by trees.
A small cabin with a fire pit and a table, surrounded by trees.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
United States
Nirumol
CA $131
CA $205 total
includes taxes & fees
Oct 21 - Oct 22
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A lakeside patio with Adirondack chairs, a fire pit, and a dock extending into the water.
A modern building with a glass facade, outdoor seating area, and a flag.
A spacious kitchen with wooden cabinets, a granite countertop, and a view of the lake through large windows.
A spacious kitchen with a large island, a dining area with white furniture, and a living room with a fireplace.

9. Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit

Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
Seneca
CA $544
CA $1,097 total
includes taxes & fees
Sep 27 - Sep 28
Beautiful Lake Keowee Home w/ Boat Dock & Fire Pit
A golf course with a water body, trees, and a distant view of a bridge.
A modern building with a central entrance, surrounded by a well-maintained lawn and trees.
An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.
A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

10. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
United States
Jennifer
CA $156
CA $174 total
includes taxes & fees
Sep 23 - Sep 24
Clemson University's James F. Martin Inn
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Top Seneca Hotel Reviews

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