Title: Best Seneca Apart hotels from CA $107 | Expedia.ca [Hotels in Seneca](https://expedia.ca/Seneca-Hotels.d6548.Travel-Guide-Hotels)[Vacation Rentals in Seneca](https://expedia.ca/Seneca-Vacation-Rentals.d6548.Travel-Guide-VacationRentals)[Flights to Seneca](https://expedia.ca/Cheap-Flights-To-Seneca.d6548.Travel-Guide-Flights)[Seneca Car Rentals](https://expedia.ca/Car-Rentals-In-Seneca.d6548.Car-Rental-Guide)[Seneca Vacation Packages](https://expedia.ca/Seneca.d6548.Destination-Travel-Guides) ![Lake Keowee South Carolina](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6548/8356140f-bae9-4afc-8d65-c18efc5581aa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=6548&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Seneca ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Queen Bed (View) | Private kitchen](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/cf119645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Seneca 9.8/10 Exceptional (66 reviews) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beonca CA $136 CA $210 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seneca Clemson Area US-123 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) Downtown 8.0/10 Very good (689 reviews) "Everting was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $107 CA $126 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/w1536h2048x0y0-6998e207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/ad885ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/511c9b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave](https://images.trvl-media.com/lodging/123000000/122340000/122332400/122332322/405dd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Clemson TIny House Cabin [](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) Seneca CA $172 CA $299 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Clemson-TIny-House-Cabin.h122332322.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/589bd84f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakeside Lodge Clemson [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) Seneca 9.0/10 Wonderful (1,002 reviews) "Great place and location, great mattress, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey CA $150 CA $186 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/40d3b059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/45872750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/89ea8ad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96160000/96153700/96153668/1da4db10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clemson Cottage - 3.6 mi. to Memorial Stadium [](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) Seneca 10/10 Exceptional (16 reviews) "Seriously comfortable home, the beds and pillows all fantastic, nicely appointed in every way. Can’t wait to stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan CA $247 CA $542 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Seneca-Hotels-The-Clemson-Cottage-36-Mi-To-Memorial-Stadium.h96153668.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/56ab80ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/72b1141f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/79b68f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/14900/14854/0d1cab6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Seneca / Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) Seneca 6.8/10 (733 reviews) "Very nice and helpful at the fronte desk. Nice room and very comfortable bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal CA $97 CA $107 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Seneca-Clemson-Area.h14854.Hotel-Information) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/67979a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/e2588273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/4513793e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100790000/100784300/100784243/424e1883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly! [](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) Seneca 10/10 Exceptional (12 reviews) "Very clean and comfortable - very close to Clemson and easy access. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim A. CA $206 CA $273 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Camper-In-Clemson-Hills-5-Minutes-From-Clemson-University-Pet-Friendly.h100784243.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/81368585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/w3595h2400x2y0-f6b7bf8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/a8e10940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684200/96684171/4ca7222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #5, two King beds. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information) Downtown 9.6/10 Exceptional (15 reviews) "We had a wonderful visit- clean and beautifully decorated. It was a little bit unusual to not have a window but very nice stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel L. CA $192 CA $304 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-5.h96684171.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/d8935835.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/6e60740f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/w3593h2396x0y4-6a05a271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683100/96683053/6cb85c45_edited_39b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Room #3 [](https://www.expedia.ca/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information) Downtown 9.0/10 Wonderful (14 reviews) "Very clean and comfortable! Will stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph K. CA $192 CA $304 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Private-Room-3.h96683053.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/d01661a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/d5db31e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/6a47ad84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96684400/96684378/w3595h2400x2y0-e25c3f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #6, King Bed. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information) Downtown 9.2/10 Wonderful (24 reviews) "Great stay. Super cute decor. Loved the location. Will be staying again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) denise n. CA $192 CA $304 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-6.h96684378.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/62fa3a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/ac7a917f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/b202edd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Seneca Clemson [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) Seneca 9.2/10 Wonderful (817 reviews) "The hotel was very clean staff was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford CA $154 CA $169 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/4221d907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/d4449aba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/w3595h2400x2y0-3b5171a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96690000/96683400/96683303/w3595h2397x0y3-dd9aef5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique hotel in historic downtown Seneca. Room #4, King bed. [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information) Downtown 9.6/10 Exceptional (18 reviews) "Great spot! Have stayed several different times and always come back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashleigh G. CA $192 CA $304 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Boutique-Hotel-In-Historic-Downtown-Seneca-Room-4.h96683303.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/52f82f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/313b57b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/aca2d330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Seneca-Clemson Area [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) Seneca 9.2/10 Wonderful (685 reviews) "Rooms good for the night. No issues with rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sofia CA $173 CA $190 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/74c3a859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/84e2f8d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/fc19a084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/51000000/50270000/50261400/50261396/6f1e18f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tucker Farm Cottage on Century Farm [](https://www.expedia.ca/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information) Seneca 10/10 Exceptional (33 reviews) "Excellent stay, beautiful area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara W. CA $187 CA $498 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Seneca-Hotels-Tucker-Farm-Cottage-On-Century-Farm.h50261396.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/436516e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/9428aa30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/ff2ee17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/345ab4fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Adventures \~ Peaceful Lakefront Home on Keowee \~ 7 Miles from Clemson! [](https://www.expedia.ca/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information) Seneca 9.8/10 Exceptional (59 reviews) "We had a beautiful stay over Thanksgiving in this very cozy lake house. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felicia L. CA $493 CA $848 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c0b82041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/5fc6414e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/b1844261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/118000000/117650000/117644500/117644416/c2f5c321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Enjoy one of our RV units son less of a headache for you this vacation! [](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information) Seneca 8.0/10 Very good (4 reviews) "My partner and I stayed 5 nights and we enjoyed it so much. It's such a convenient place to reside for a get away. If you're looking for that "outback" feeling but want to be cozy; look no further. Communication was always qick with responses and was more than willing to help with anything we needed! We would definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise s. CA $112 CA $229 total includes taxes & fees Apr 1 - Apr 2 [](https://www.expedia.ca/Seneca-Hotels-Cozy-Campground-In-Enchanting-Seneca-With-AC.h117644416.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/81e73e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/2c84c92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (214 reviews) "Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $165 CA $181 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/825f9309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/ce0e5825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/91ac5b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, stereo](https://images.trvl-media.com/lodging/25000000/24160000/24156000/24155990/735219a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger [](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) Serenity Bay 9.8/10 Exceptional (130 reviews) "Beautiful home, well furnished, very clean, easy TV" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan CA $515 CA $983 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Seneca-Hotels-Deepwater-Cove-On-Lake-Keowee-Complete-With-Dock-And-Kayaks-EV-Charger.h24155990.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/0834ba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/ab96edf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/c941d493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/121000000/120090000/120082600/120082534/51bdec15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock [](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) Seneca 8.8/10 Excellent (5 reviews) "Everything was in great condition! Items provided were good quality. You can tell a lot of time and thought has been put into this property. We would love to stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alisa W. CA $225 CA $403 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Seneca-Hotels-Lakefront-Tiny-Home-Retreat-On-Hartwell-Near-CU.h120082534.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/e032590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/9b29fdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/518d0c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/115000000/114550000/114542100/114542071/bc9bfba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom house with WiFi and AC in serene Seneca on Lake Hartwell [](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) Seneca 10/10 Exceptional (9 reviews) "We enjoyed our stay. Had everything we needed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane S. CA $336 CA $722 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Seneca-Hotels-Charming-3-Bedroom-House-With-WiFi-And-AC-In-Serene-Seneca-On-Lake-Hartwell.h114542071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=6548&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT) Condos [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO) Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL) Villas [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VILLA) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.ca/Hotel-Search?destination=Seneca%2C+South+Carolina%2C+United+States+of+America®ionId=6548&latLong=34.685654%2C-82.953201&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Apart-Hotels.d6548-aaApartHotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSeneca-Apart-Hotels.d6548-aaApartHotels.Travel-Guide-Accommodation) ## Top Seneca Hotel Reviews ![New to VRBO! Big water views, private dock, pool table, 15 min Clemson!](https://images.trvl-media.com/lodging/58000000/57950000/57941100/57941024/eb68ea9e_y.jpg) ### New to VRBO! Big water views, private dock, pool table, 15 min Clemson! 10/10 Excellent "We enjoyed our stay at your property very much.Everything was exceptionally clean and well taken care of. Thank you for quickly addressing the issue with the heat pump." [](https://expedia.ca/Anderson-Hotels-Large.h57941024.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 10/10 Excellent "All of the staff we encountered were extremely nice and helpful. The beds were very comfortable thoroughly enjoyed our stay." [](https://expedia.ca/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Lakeside Lodge Clemson](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90_y.jpg) ### Lakeside Lodge Clemson 10/10 Excellent "The unit was terrific. Quiet and clean. only issue is daily train whistle nearby. Nice area with grrat restaurant in hotel. " [](https://expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Loved our time here! Staff was super sweet and helpful. Room was very nice and the bed very cozy. Room felt a little small but the bathroom was larger than expected, and again all nice and clean. No complaints! Great place to stay when in the area! Love the mission to help those differently abled, as well!!" [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Best Western Seneca-Clemson](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/eaa8fc9a_y.jpg) ### Best Western Seneca-Clemson 10/10 Excellent "Clean room! Great staff! " [](https://expedia.ca/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "I enjoyed my stay at the BW Plus. It's super convenient (I walked home from downtown one night - not a short walk but very manageable). The property was clean, the staff was VERY friendly, the room was more than adequate (I had 2 queens and it had a desk/chair and side chair with 'breakfast tray.' The bathroom was just fine. The breakfast area is HUGE and has all you need to get started in the morning, plus they have ping pong and ample seating for groups. I have already booked stays for the fall." [](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Tru by Hilton Seneca Clemson](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283_y.jpg) ### Tru by Hilton Seneca Clemson 10/10 Excellent "Clean room, friendly staff. Great place to stay!" [](https://expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information) ![Fairfield Inn & Suites Seneca Clemson Univ Area ](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5_y.jpg) ### Fairfield Inn & Suites Seneca Clemson Univ Area 10/10 Excellent "Clean room freindly staff and convenient location to stores" [](https://expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!](https://images.trvl-media.com/lodging/34000000/33730000/33728200/33728167/7de7c272_y.jpg) ### 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly! 10/10 Excellent "The home was beautiful, the amenities fantastic, and we especially enjoyed the kayaks! The kitchen was also stocked with all the basics we needed which saved us from additional grocery expense for items we would only be using for a couple of days. The owner was also a delight to work with. Wonderful experience!" [](https://expedia.ca/Anderson-Hotels-Beautiful-43.h33728167.Hotel-Information) ## Find out more about Seneca ## Seneca Aparthotels information | Number of reviews | 3,702 | | ----------------- | ------------- | | Accommodation | 1 Aparthotels | | Lowest Price | CA $107 | | Highest Price | CA $848 | ## Frequently asked questions ### What should I expect during my Seneca aparthotel stay? ### What are the favorite aparthotels for my visit to Seneca? ### How many aparthotels will I find in Seneca? ### What should I see and do in Seneca? ### What is an aparthotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Aparthotels in Central ](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central ](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Boutique Hotels in Central ](https://www.expedia.ca/Central-Hotels-Boutique-Hotel.0-0-d10503-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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