Title: Book the Best Clemson LUXURY Hotels - Upscale Hotels in Clemson, SC | Expedia.ca [Clemson Travel Guide](https://expedia.ca/Clemson.dx6594)[Hotels in Clemson](https://expedia.ca/Clemson-Hotels.d6594.Travel-Guide-Hotels)[Vacation Rentals in Clemson](https://expedia.ca/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals)[Flights to Clemson](https://expedia.ca/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)[Things to do in Clemson](https://expedia.ca/Things-To-Do-In-Clemson.d6594.Travel-Guide-Activities)[Clemson Car Rentals](https://expedia.ca/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)[Clemson Vacation Packages](https://expedia.ca/Clemson.d6594.Destination-Travel-Guides) ![Sunset on the Docks in Clemson, South Carolina; Shutterstock ID 1068665087; purchase_order: SP-1269 HA 2018 Batch 1; Order: ; client: ; other:](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Clemson, SC - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Clemson Luxury Hotels Tonight [Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-12-29&endDate=2025-12-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 30 - Dec 31](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2025-12-30&endDate=2025-12-31&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6594&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Clemson luxury hotels ![In-room safe, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/ee0e0eea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (745) "Staff was amazing and our room was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda R CA $229 CA $255 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e408dd97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (558) "location is amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) colleen [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a75f160d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/8c83b96e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (78) "The owners are amazing. Comfy rooms, stellar breakfast and good people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee CA $155 CA $241 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | Living room](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/63caaad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/9a24528f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Private kitchen](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/f8ba8fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson [](https://www.expedia.ca/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Anderson CA $168 CA $414 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-12&endDate=2026-01-13®ionId=6594&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Top Clemson Hotel Reviews ![Quality Inn Clemson near University](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/01de7c97_y.jpg) ### Quality Inn Clemson near University 8/10 Good "Yes very" [](https://expedia.ca/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) ![Days Inn by Wyndham Clemson](https://images.trvl-media.com/lodging/1000000/20000/15700/15694/a2328ab3_y.jpg) ### Days Inn by Wyndham Clemson 10/10 Excellent "Everything was up to standards and John was very helpful and polite " [](https://expedia.ca/Clemson-Hotels-Days-Inn-By-Wyndham-Clemson.h15694.Hotel-Information) ## Frequently asked questions ### What are the top-rated luxury hotels in Clemson? > The 4-star Shepherd Hotel Downtown Clemson, with an impressive 9.8 rating, consistently receives praise for its friendly and great staff, beautiful and clean rooms, and convenient location. Guests frequently highlight the comfortable beds and the nice bar. > > > The Abernathy of Clemson, also a 4-star establishment, boasts a 9.6 rating. Customers often praise the clean and spacious rooms, the helpful and friendly staff, and the hotel's excellent location and amenities. The friendly bar is also a recurring positive mention. ### Which area of Clemson is best to stay in for luxury hotels? > For those prioritising convenient access to the university and its amenities, the area directly adjacent to the Clemson University campus offers several premium options. While not a distinct neighbourhood, hotels here are generally modern and cater to university visitors, often featuring high-end fitness equipment and upscale dining. This area suits visitors attending university events, parents visiting students, or alumni wanting to be close to their alma mater. > > > Another excellent choice for luxury hotels is along the US-123 corridor, particularly near the intersection with SC-93\. This area provides easy access to both the university and the broader Clemson region. Hotels here often boast larger grounds, resort-style amenities like outdoor pools and sophisticated dining, and a more expansive feel. ### How much does a luxury hotel in Clemson cost? ### Which luxury hotels in Clemson are good for families? > The Shepherd Hotel Downtown Clemson, a 4-star establishment with a 9.8 rating, offers beautiful and clean rooms, as well as a great and convenient location. Customers frequently comment on the friendly and helpful staff, and the comfortable beds. > > > The 4-star Abernathy of Clemson, rated 9.6, provides big and clean rooms along with amenities such as free self-parking and accessible parking. Reviewers consistently praise the friendly and helpful staff, and the hotel's great location. ### Are there any top luxury hotels near Lake Hartwell? > The 4-star Shepherd Hotel Downtown Clemson, with an impressive 9.8 rating, is frequently praised for its beautiful, clean rooms and convenient location. Guests consistently highlight the friendly staff and the comfortable beds, ensuring a restful stay. > > > The 4-star Abernathy of Clemson, rated 9.6, offers spacious, clean rooms and a great location. Reviewers often praise the helpful and friendly staff, as well as the good amenities available. ### How can I save on a luxury hotel in Clemson with Expedia? ### Is it cheaper to book a luxury Clemson hotel and flights as a package? ### Can I cancel my luxury hotel reservation on Expedia? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Aparthotels in Central ](https://www.expedia.ca/Central-Apart-Hotels.d10503-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Central ](https://www.expedia.ca/Central-Bed-And-Breakfast.d10503-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Boutique Hotels in Central ](https://www.expedia.ca/Central-Hotels-Boutique-Hotel.0-0-d10503-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Central ](https://www.expedia.ca/Central-Hotels-Business-Hotel.0-0-d10503-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Central ](https://www.expedia.ca/Central-Hotels-Golf-Hotel.0-0-d10503-tGolfHotel.Travel-Guide-Filter-Hotels) - 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